Faculty

Alanna Strong, MD, PhD

Assistant Professor of Pediatrics (Human Genetics)

Department: Pediatrics

Graduate Group Affiliations

Cell and Molecular Biology

Contact information

Children's Hospital of Philadelphia
Division of Human Genetics
3615 Civic Center Blvd
Abramson Research Center, Room 1016D
Philadelphia, PA 19104

Office: 267-582-0429

Email:
strong.alanna@gmail.com

Education:
BA (Biology)
University of Pennsylvania, 2005.
PhD (Cellular and Molecular Biology)
University of Pennsylvania, 2012.
MD
University of Pennsylvania, 2014.

Permanent link

> Perelman School of Medicine > Faculty > Details

Description of Clinical Expertise

Genetics, genetic liver diseases, genetic kidney diseases, ciliopathy

Description of Research Expertise

Ciliopathy, cilium, hepatobiliary disease, kidney disease

Selected Publications

Cardinale CJ, Liu Y, Kevadia A, Strong A, Watts VJ, Hakonarson H: The ulcerative colitis risk gene adenylyl cyclase 7 restrains the T helper 2 phenotype and Class II antigen presentation. J Crohns Colitis 2025.

Watson D, Mentch F, Billings J, Ostberg K, March ME, Kalish JM, Li D, Cannon I, Guay-Woodford LM, Hartung E, Strong, A. : Elucidating the Molecular Landscape of Cystic Kidney Disease: Old Friends, New Friends and Some Surprises. Am J Med Genet A 2025.

Gold JI, Strong A, Gold NB, Yudkoff M, Szalda D, Jan S, Schwartz LA, Ganetzky R: Executive and adaptive function impacts long-term outcomes for adults with maple syrup urine disease. Journal of Inherited Metabolic Disease 2025.

Pingault V, Neiva-Vaz C, de Oliveira J, Martínez-Gil N, Lasa-Aranzasti A, Campos B, Lakeman IMM, Nibbeling EAR, Stoeva R, Jayakar P, Dabir T, Elloumi HZ, Strong A, Hanein S, Picard A, Ochsenbein F, Blanc P, Amiel J : Chromatin assembly factor subunit CHAF1A as a monogenic cause for oculo-auriculo-vertebral spectrum. European Journal of Human Genetics 2025.

Landau-Prat D, Marshall R, Strong A, Katowitz JA, Katowitz WR: Punctal Atresia As a Clinical Indicator of Systemic Genetic Anomalies. Semin Ophthalmol. Page: 1-4, April 2024 Notes: doi: 10.1080/08820538.2024.2345291. Online ahead of print.

Stanley HM, White BR, LaRosa CJ, Cocalis MW, Gaynor JW, Strong A, Gangaram B.: Patent ductus arteriosus and coarctation of the aorta in association with PRDM6 variants. Am J Med Genet A. 194(4): e63500, April 2024 Notes: doi: 10.1002/ajmg.a.63500. Epub 2023 Dec 9.

Brunet T, Zott B, Lieftüchter V, Lenz D, Schmidt A, Peters P, Kopajtich R, Zaddach M, Zimmermann H, Hüning I, Ballhausen D, Staufner C, Bianzano A, Hughes J, Taylor RW, McFarland R, Devlin A, Mihaljević M, Barišić N, Rohlfs M, Wilfling S, Sondheimer N, Hewson S, Marinakis NM, Kosma K, Traeger-Synodinos J, Elbracht M, Begemann M, Trepels-Kottek S, Hasan D, Scala M, Capra V, Zara F, van der Ven AT, Driemeyer J, Apitz C, Krämer J, Strong A, Hakonarson H, Watson D, Mayr JA, Prokisch H, Meitinger T, Borggraefe I, Spiegler J, Baric I, Paolini M, Gerstl L, Wagner M.: De novo variants in RNF213 are associated with a clinical spectrum ranging from Leigh syndrome to early-onset stroke. Genet Med. 26(2): 101013, Feb 2024 Notes: doi: 10.1016/j.gim.2023.101013. Epub 2023 Nov 1.

Zhou MS, Lee CD, Lerman BJ, Strong A, LaRosa C.: An Adolescent Boy With Hypoxia, Microscopic Hematuria, and Hypertension. Cureus 16(1): e52738, Jan 2024 Notes: doi: 10.7759/cureus.52738. eCollection 2024 Jan.

Strong A, March ME, Cardinale CJ, Liu Y, Battig MR, Finoti LS, Matsuoka LS, Watson D, Sridhar S, Jarrett JF, Cannon I, Li D, Bhoj E, Zackai EH, Rand EB, Wenger T, Lerman BB, Shikany A, Weaver KN, Hakonarson H.: Novel insights into the phenotypic spectrum and pathogenesis of Hardikar syndrome. Genetics In Medicine 2024.

Marshall RF, Landau-Prat D, Strong A, Katowitz JA, Katowitz WR. : Ocular and Systemic Abnormalities in Punctal Agenesis. Ophthalmic Plast Reconstr Surg 2024.