Alice S. Chen-Plotkin, MD

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Parker Family Professor of Neurology
Department: Neurology

Contact information
Hospital of the University of Pennsylvania
150 Johnson Pavilion
Philadelphia, PA 19104
Office: 215-829-6500
Lab: 215-746-8191
AB (English)
Harvard-Radcliffe College, 1996.
MSc (Biology)
University of Oxford, 1998.
Harvard Medical School, 2003.
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Description of Research Expertise

The over-arching goal of our research is to better understand the mechanisms of neurodegenerative disease in order to intervene in these disease processes.

Our general approach is to use unbiased genomic- or proteomic-scale screens in human-derived materials to generate leads, which are then followed mechanistically in relevant systems including neuronal culture and in vivo animal models. The pace of technology development is allowing us to acquire more data, faster, than ever before, but this does not always translate into biological understanding. We believe that to unlock the true potential of leads generated in this way, computational methods must work hand-in-hand with bench-based manipulative experiments.

Description of Clinical Expertise

Movement disorders
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Last updated: 06/27/2023
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