Faculty

Richard Edmund Phillips, MD PhD

Presidential Assistant Professor of Neurology

Department: Neurology

Graduate Group Affiliations

Contact information

Hospital of the University of Pennsylvania
Department of Neurology
3400 Spruce Street, 3 West Gates
Philadelphia, PA 19104

Education:
BSc (Genetics)
University College London, 2001.
MD (Medicine)
Kings' College London, 2009.
PhD (Immunology)
King's College London, 2009.

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Dáire Gannon, Eimear Lagan, Ademar Jesus Silva, Peter Bibawi, Anthony M. Doherty, Darragh Nimmo, Rachel McCole, Craig Monger, Giovani Genesi, Aurelie Vanderlinden Dibekeme, James A. Innes, Lu Yang, Bryan Chen, Guido van Mierlo, Pascal W.T.C Jansen, Keiran Wynne, Fran-cisco J. Sánchez-Rivera, Yadira M. Soto-Feliciano, Michiel Vermeulen, Giorgio Oliverio, Chun-Wei Chen, Richard E. Phillips, Adrian P. Bracken, Gerard L. Brien: Specific cPRC1 complexes are co-opted to mediate oncogenic gene repression in diffuse midline glioma. Biorxiv December 2023.

Liang R., Tomita D. Sasaki Y., Ginn J,, Michino M., Huggins D., Baxt L., Kargman S., Shahid M., Kazuyoshi A., Duggan M., Stamford A., DeStanchina E., Liverton N., Meinke P., Foley M., Phillips R.E. : A chemical strategy toward brain penetrant EZH2 inhibitors. ACS Medicinal Chemistry Letters 13(3): 377–387, 2022.

Phillips RE, Soshnev AA, Allis CD. : Epigenomic Reprogramming as a Driver of Malignant Glioma. Cancer Cell 38(5): 647-660, 2020.

Phillips, R. E., Yang, Y., Smith, R. C., Thompson, B. M., Yamasaki, T., SotoFeliciano, Y. M., Funato, K., Liang, Y., Garcia-Bermudez, J., Wang, X., Garcia, B. A., Yamasaki, K., McDonald, J. G., Birsoy, K., Tabar, V., & Allis, C. D. : Target identification reveals lanosterol synthase as a vulnerability in glioma. Proceedings of the National Academy of Sciences of the United States of America 116(16): 7957–7962, 2019.

Phillips, R. E., Curran, K. J., & Khakoo, Y : Management of late extraneural recurrence of medulloblastoma without high-dose chemotherapy. Journal of Neuro-Oncology 124(3): 523–524, 2015.

Awosika, O. O., Lyons, J. L., Ciarlini, P., Phillips, R. E., Alfson, E. D., Johnson, E. L., Koo, S., Marty, F., Drew, C., Zaki, S., Folkerth, R. D., & Klein, J. P. : Fatal adenovirus encephalomyeloradiculitis in an umbilical cord stem cell transplant recipient. Neurology 80(18): 1715–1717, 2013.

Bartel, G., Brown, K., Phillips, R., Peng, Q., Zhou, W., Sacks, S. H., & Wong, W. : Donor specific transplant tolerance is dependent on complement receptors. Transplant International 26(1): 99-108, 2013.

Wood, B. R., Klein, J. P., Lyons, J. L., Milner, D. A., Phillips, R. E., Schutten, M., Folkerth, R. D., Ciarlini, P., Henrich, T. J., & Johnson, J. A. : HIV-2 encephalitis: Case report and literature review. AIDS Patient Care and STDs 26 (7): 383–387 2012.

Brown, K., Phillips, R. E., & Wong, W : What have we learnt from experimental renal transplantation? Nephron Experimental Nephrology 115(1): e9-e14, 2010.

Moxham, V. F., Karegli, J., Phillips, R. E., Brown, K. L., Tapmeier, T. T., Hangartner, R., Sacks, S. H., & Wong, W. : Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection. Journal of Immunology 180 (6): 3910–3918, 2008.