Andrea L. Stout

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Director C, Perelman School of Medicine, Dept. of Cell & Developmental Biology
Department: Cell and Developmental Biology

Contact information
421 Curie Boulevard
1107 Biomedical Research Building II/III
Philadelphia, PA 19104
Office: 215-573-3942
Education:
BA (Physics)
Lawrence University, 1986.
Ph.D. (Biophysics)
The University of Michigan, Ann Arbor, 1993.
Post-Graduate Training
Post-doctoral fellow in Applied and Engineering Physics, Cornell University, 1993-1996.
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Description of Research Expertise

My expertise is in light microscopy, with special emphasis on confocal and super-resolution microscopy. My background is in physics and biophysics, specifically using optical methods to probe cellular and molecular dynamics. As Director of the CDB Microscopy Core, I combine these skills with my experience and interest in science education to provide training and imaging services on a variety of cutting-edge commercial microscopes to the Penn research community.

Selected Publications

Huang Jianhe, Min Lu Min, Cheng Lan, Yuan Li-Jun, Zhu Xiaoquing, Stout Andrea L, Chen Mary, Li Jian, Parmacek Michael S: Myocardin is required for cardiomyocyte survival and maintenance of heart function. Proceedings of the National Academy of Sciences of the United States of America 106(44): 18734-9, Nov 2009.

Liu Fang, Levin Mark D, Petrenko Nataliya B, Lu Min Min, Wang Tao, Yuan Li Jun, Stout Andrea L, Epstein Jonathan A, Patel Vickas V: Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin. Journal of molecular and cellular cardiology 45(6): 715-23, Dec 2008.

Granger Anne, Abdullah Ibrahim, Huebner Faith, Stout Andrea, Wang Tao, Huebner Thomas, Epstein Jonathan A, Gruber Peter J: Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22(10): 3549-60, Oct 2008.

Stout Andrea L, Wang Jushuo, Sanger Jean M, Sanger Joseph W: Tracking changes in Z-band organization during myofibrillogenesis with FRET imaging. Cell motility and the cytoskeleton 65(5): 353-67, May 2008.

Sanger Joseph W, Kang Songman, Siebrands Cornelia C, Freeman Nancy, Du Aiping, Wang Jushuo, Stout Andrea L, Sanger Jean M: How to build a myofibril. Journal of muscle research and cell motility 26(6-8): 343-54, 2005.

Stout A L: Detection and characterization of individual intermolecular bonds using optical tweezers. Biophysical journal 80(6): 2976-86, Jun 2001.

Stout A L, Webb W W: Optical force microscopy. Methods in cell biology 55: 99-116, 1998.

Stout A L, Axelrod D: Spontaneous recovery of fluorescence by photobleached surface-adsorbed proteins. Photochemistry and photobiology 62(2): 239-44, Aug 1995.

Stout A L, Axelrod D: Reversible binding kinetics of a cytoskeletal protein at the erythrocyte submembrane. Biophysical journal 67(3): 1324-34, Sep 1994.

Stout A L, Axelrod D: Evanescent field excitation of fluorescence by epi-illumination microscopy. Applied optics 28(24): 5237-42, Dec 1989.

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Last updated: 08/17/2018
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