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Chi Van Dang, MD, PhD
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Adjunct Professor of Medicine (Hematology-Oncology)
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Department: Medicine
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Contact information
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Abramson Cancer Center
23 3400 Civic Center Boulevard
20 South Pavilion Expansion
3b 12th floor, Suite 12-114
Philadelphia, PA 19104
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23 3400 Civic Center Boulevard
20 South Pavilion Expansion
3b 12th floor, Suite 12-114
Philadelphia, PA 19104
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Office: 215-662-3929
32 Fax: 215-662-4020
32 Lab: 215-746-5528
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32 Fax: 215-662-4020
32 Lab: 215-746-5528
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Education:
21 7 BS 16 (Chemistry) c
2f University of Michigan, 1975.
21 8 PhD 16 (Chemistry) c
2e Georgetown University, 1978.
21 7 MD 1e (Internal Medicine) c
44 Johns Hopkins University School of Medicine, 1982.
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Permanent link21 7 BS 16 (Chemistry) c
2f University of Michigan, 1975.
21 8 PhD 16 (Chemistry) c
2e Georgetown University, 1978.
21 7 MD 1e (Internal Medicine) c
44 Johns Hopkins University School of Medicine, 1982.
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16b Fan TWM, Bruntz RC, Yang Y, Song H, Chernyavskaya Y, Deng P, Zhang Y, Shah PP, Beverly LJ, Qi Z, Mahan AL, Higashi RM, Dang CV, Lane AN.: De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues. J Biol Chem 294(36): 13464-13477, Sep 6 2019.
e2 Walton ZE, Brooks RC, Dang CV.: mTOR Senses Intracellular pH through Lysosome Dispersion from RHEB. Bioessays. Wiley (eds.). 41(7): e1800265, Jul 2019.
19e Agarwal E1,2, Altman BJ3,4, Seo JH1,2, Ghosh JC1,2, Kossenkov AV5, Tang HY5, Krishn SR1,6, Languino LR1,6, Gabrilovich DI1,2, Speicher DW1,5,7, Dang CV7,8, Altieri DC9,2.: Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth. J Biol Chem. 294(27): 10407-10414, Jul 5 2019.
16e Agarwal E, Altman BJ, Ho Seo J, Bertolini I, Ghosh JC, Kaur A, Kossenkov AV, Languino LR, Gabrilovich DI, Speicher DW, Dang CV, Altieri DC.: Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis. Mol Cell Biol. 39(14): pii: e00109-19. Jun 27 2019.
c3 Brooks RC, Dang CV.: Autophagy: clocking in for the night shift. EMBO J. Wiley (eds.). 38(12): pii: e102434. Jun 17 2019.
1d2 Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein P, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A.: Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma. Leukemia Mar 26 2019 Notes: doi: 0.1038/s41375-019-0454-4. [Epub ahead of print]
1b7 Yuan J, Hu Z, Mahal BA, Zhao SD, Kensler KH, Pi J, Hu X, Zhang Y, Wang Y, Jiang J, Li C, Zhong X, Montone KT, Guan G, Tanyi JL, Fan Y, Xu X, Morgan MA, Long M, Zhang Y, Zhang R, Sood AK, Rebbeck TR, Dang CV, Zhang L.: Integrated Analysis of Genetic Ancestry and Genomic Alterations across Cancers. Cancer Cell. Elsevier Science (eds.). 34(4): 549-560.e9. Oct 8 2018.
123 Zhang L, Peng D, Sood AK, Dang CV, Zhong X.: Shedding Light on the Dark Cancer Genomes: Long Noncoding RNAs as Novel Biomarkers and Potential Therapeutic Targets for Cancer. Mol Cancer Ther. 17(9): 1816-1823, Sep 2018.
cc Dang CV.: The Half-Lives of Facts, Paradigm Shifts, and Reproducibility in Cancer Research. Cancer Res 78(15): 4105-4106, Aug 2018.
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Selected Publications
199 Gouw AM, Margulis K, Liu NS, Raman SJ, Mancuso A, Toal GG, Tong L, Mosley A, Hsieh AL, Sullivan DK, Stine ZE, Altman BJ, Schulze A, Dang CV, Zare RN, Felsher DW.: The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth. Cell Metab. 30(3): 556-572.e5, Sep 3 2019.16b Fan TWM, Bruntz RC, Yang Y, Song H, Chernyavskaya Y, Deng P, Zhang Y, Shah PP, Beverly LJ, Qi Z, Mahan AL, Higashi RM, Dang CV, Lane AN.: De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues. J Biol Chem 294(36): 13464-13477, Sep 6 2019.
e2 Walton ZE, Brooks RC, Dang CV.: mTOR Senses Intracellular pH through Lysosome Dispersion from RHEB. Bioessays. Wiley (eds.). 41(7): e1800265, Jul 2019.
19e Agarwal E1,2, Altman BJ3,4, Seo JH1,2, Ghosh JC1,2, Kossenkov AV5, Tang HY5, Krishn SR1,6, Languino LR1,6, Gabrilovich DI1,2, Speicher DW1,5,7, Dang CV7,8, Altieri DC9,2.: Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth. J Biol Chem. 294(27): 10407-10414, Jul 5 2019.
16e Agarwal E, Altman BJ, Ho Seo J, Bertolini I, Ghosh JC, Kaur A, Kossenkov AV, Languino LR, Gabrilovich DI, Speicher DW, Dang CV, Altieri DC.: Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis. Mol Cell Biol. 39(14): pii: e00109-19. Jun 27 2019.
c3 Brooks RC, Dang CV.: Autophagy: clocking in for the night shift. EMBO J. Wiley (eds.). 38(12): pii: e102434. Jun 17 2019.
1d2 Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein P, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A.: Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma. Leukemia Mar 26 2019 Notes: doi: 0.1038/s41375-019-0454-4. [Epub ahead of print]
1b7 Yuan J, Hu Z, Mahal BA, Zhao SD, Kensler KH, Pi J, Hu X, Zhang Y, Wang Y, Jiang J, Li C, Zhong X, Montone KT, Guan G, Tanyi JL, Fan Y, Xu X, Morgan MA, Long M, Zhang Y, Zhang R, Sood AK, Rebbeck TR, Dang CV, Zhang L.: Integrated Analysis of Genetic Ancestry and Genomic Alterations across Cancers. Cancer Cell. Elsevier Science (eds.). 34(4): 549-560.e9. Oct 8 2018.
123 Zhang L, Peng D, Sood AK, Dang CV, Zhong X.: Shedding Light on the Dark Cancer Genomes: Long Noncoding RNAs as Novel Biomarkers and Potential Therapeutic Targets for Cancer. Mol Cancer Ther. 17(9): 1816-1823, Sep 2018.
cc Dang CV.: The Half-Lives of Facts, Paradigm Shifts, and Reproducibility in Cancer Research. Cancer Res 78(15): 4105-4106, Aug 2018.
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