Faculty
Brian R White, MD, PhD
Assistant Professor of Pediatrics (Cardiovascular Medicine)
Department: Pediatrics
Graduate Group Affiliations
Contact information
Children's Hospital of Philadelphia
Abramson Research Center, 907C
3615 Civic Center Blvd.
Philadelphia, PA 19104
Abramson Research Center, 907C
3615 Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-283-7835
Fax: 215-590-5825
Lab: 215-590-3548
Fax: 215-590-5825
Lab: 215-590-3548
Email:
brian.white@post.harvard.edu
brian.white@post.harvard.edu
Publications
Education:
BA (Physics)
Harvard University, 2004.
MD
Washington University School of Medicine in St. Louis, 2012.
PhD (Physics)
Washington University School of Medicine in St. Louis, 2012.
Permanent linkBA (Physics)
Harvard University, 2004.
MD
Washington University School of Medicine in St. Louis, 2012.
PhD (Physics)
Washington University School of Medicine in St. Louis, 2012.
Description of Clinical Expertise
I am a pediatric cardiologist with expertise in both general cardiology outpatient care as well as echocardiography. I treat pediatric patients with both congenital and acquired heart disease.Description of Research Expertise
My laboratory is interested in developing novel optical neuroimaging techniques to better understand pediatric neurodevelopment and its disruption by pediatric diseases (congenital heart disease, prematurity, stroke). Namely, we use optical intrinsic signal (OIS) imaging and diffuse optical tomography (DOT) along with resting-state methods such as functional connectivity. This combination of methods allows true bench-to-bedside neuroimaging. Specifically, my laboratory is interested in analytical technique development, animal models of pediatric disease, and translational studies in humans.Selected Publications
WB Baker, AM Hurlock, C Mcintosh, H Zhao, C Davis, D Anderson, B Bayle, R Goto, RM Forti, TS Ko, BR White, JM Lynch: Non-invasive Optical Biomarker Central Venous Pressure in Children with Single Ventricle Heart Defects. SPIE European Conferences on Biomedical Optics June 2025.HB Fisher, BR White: Ensemble Machine Learning Segmentation of Widefield Optical Imaging Using Spectral and Temporal Information. Optica Biophotonics Congress Apr 2025.
R Forti, BR White: Accuracy and Crosstalk of Hemoglobin Spectroscopy in Widefield Optical Imaging. Optica Biophotonics Congress Apr 2025.
Y Hao, S Vandekar, MT Jones, RT Shinohara, BR White: Addressing Missingness with Multiple Imputation in Optical Neuroimaging. Optica Biophotonics Congress Apr 2025.
Y He, JB Majeski, BR White, WB Baker, RM Forti: Monte-Carlo-based Lookup Table Method to Improve Frequency-Domain Diffuse Optical Spectroscopy Accuracy at Short Source-Detector Separations. Optica Biophotonics Congress Apr 2025.
WB Baker, AM Hurlock, H Zhao, D Anderson, B Bayle, R Goto, RM Forti, TS Ko, BR White, JM Lynch: Optical Monitoring Reveals Increased Intracranial Pressure After the Glenn Surgery in Children with Single-Ventricle Heart Defects. Optica Biophotonics Congress Apr 2025.
Y Hao, S Vandekar, MT Jones, RT Shinohara, BR White: Addressing Missing Data in Widefield Optical Neuroimaging of Functional Connectivity in Mice. ENAR Spring Meeting March 2025.
A Asadian, D Derman, T Adepoju, BR White, SL Ferradal: Anesthetic effects on functional connectivity fingerprinting in mice. SPIE Photonics West Jan 2025.
H Zhao, B Scammon, J Wu, TS Ko, BR White, RM Forti, JM Kainerstorfer, WB Baker: Estimating intracranial pressure with optically-measured cerebral blood flow cardiac waveforms in pigs. SPIE Photonics West Jan 2025.
RM Forti, LJ Hobson, SL Morton, A Hurlock, R Goto, D Andersona MK Weeks, K Senthil, BR White, TS Ko, KD Browne, DK Cullen, AG Yodh, TJ Kilbaugh, WB Baker: Non-invasive diffuse optical monitoring of cerebral physiology after severe closed-head diffuse injury in swine. SPIE Photonics West Jan 2025.
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