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Loretta M. Flanagan-Cato, PhD
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Graduate Group Affiliations
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Contact information
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D18 Psychology Lab Building
35 3720 Walnut Street
Philadelphia, PA 19104
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35 3720 Walnut Street
Philadelphia, PA 19104
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Office: 215-898-4085
32 Fax: 215-898-7301
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32 Fax: 215-898-7301
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Email:
flanagan@.psych.upenn.edu
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flanagan@.psych.upenn.edu
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Publications
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Education:
21 7 BA 17 (Psychology) c
2b Rutgers University, 1985.
21 8 PhD 19 (Neuroscience) c
31 University of Pittsburgh, 1990.
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21 7 BA 17 (Psychology) c
2b Rutgers University, 1985.
21 8 PhD 19 (Neuroscience) c
31 University of Pittsburgh, 1990.
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Links
9f Search PubMed for articles
42 Neuroscience graduate group faculty webpage.
70 Primary Work Website
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Permanent link9f Search PubMed for articles
42 Neuroscience graduate group faculty webpage.
70 Primary Work Website
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7b Neuroendocrinology, estrogen, receptors, adrenal steroids, angiotensin, oxytocin, dendritic spines, neuroplasticity
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1a RESEARCH INTERESTS
67 Steroid-induced plasticity of neural circuits to control reproductive and ingestive behaviors.
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1b RESEARCH TECHNIQUES
76 Neuroanatomical analysis, cell culture, western blot analysis, behavioral molecular pharmacological analysis.
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18 RESEARCH SUMMARY
1c4 Our research focuses on the cellular and molecular effects of steroids on brain networks that modulate behaviors such as mating and ingestion. To study these behaviorally-relevant neuro-hormonal interactions, a multidisciplinary approach is required. Thus, techniques ranging from behavioral analysis, immunocytochemical localization of peptide and steroid receptors, transneuronal tracing, and confocal analysis of cell morphology are employed.
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Description of Research Expertise
1b KEY WORDS:7b Neuroendocrinology, estrogen, receptors, adrenal steroids, angiotensin, oxytocin, dendritic spines, neuroplasticity
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1a RESEARCH INTERESTS
67 Steroid-induced plasticity of neural circuits to control reproductive and ingestive behaviors.
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1b RESEARCH TECHNIQUES
76 Neuroanatomical analysis, cell culture, western blot analysis, behavioral molecular pharmacological analysis.
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18 RESEARCH SUMMARY
1c4 Our research focuses on the cellular and molecular effects of steroids on brain networks that modulate behaviors such as mating and ingestion. To study these behaviorally-relevant neuro-hormonal interactions, a multidisciplinary approach is required. Thus, techniques ranging from behavioral analysis, immunocytochemical localization of peptide and steroid receptors, transneuronal tracing, and confocal analysis of cell morphology are employed.
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39 Griffin, G.D. c8 L.M. Flanagan-Cato. : Ovarian hormone action in the hypothalamic ventromedial nucleus: remodelling to regulate reproduction. J. Neuroendocrinology 23: 465-471, 2011.
e1 Flanagan-Cato, L.M. : Sex differences in the neural circuits mediating female sexual receptivity. Frontiers in Neuroendocrinology 32: 124-136, 2011.
16b Griffin, G.D., S.L. Ferri-Kolwicz, B.S. Reyes, E. J. Van Bockstaele and L.M. Flanagan-Cato. : Ovarian hormone-induced reorganization of oxytocin-labeled dendrites and synapses lateral to the hypothalamic ventromedial nucleus in female rats. J. Comparative Neurology 518: 4531-4545, 2010.
11c LaBelle, D.R., J.M. Cox, A.A. Dunn-Meynell, B.E. Levin, and L.M. Flanagan-Cato. : Genetic and dietary effects on dendrites in the hypothalamic ventromedial nucleus. Physiology and Behavior 98: 511-516, 2009.
fc Griffin, G.D. and L.M. Flanagan-Cato. : Sex differences in the dendritic arbors of neurons in the hypothalamic ventromedial nucleus. Physiology and Behavior 97: 151-156, 2009.
142 Griffin, G.D. and L.M. Flanagan-Cato. : Estradiol and progesterone differentially regulate the dendritic arbor of neurons in the hypothalamic ventromedial nucleus of the female rat (Rattus norvegicus). J. Comparative Neurology 510: 631-640, 2008.
e1 Pfaff, D.W., L.-M. Kow, M. Loose, L.M. Flanagan-Cato. : Reverse engineering the lordosis behavior circuit. Hormones and Behavior 55: 347–354, 2008.
113 Flanagan-Cato, L.M., S.J. Fluharty, E.B. Weinreb, and D.R. LaBelle. : Food restriction alters neuronal morphology in the hypothalamic ventromedial nucleus of male rats. Endocrinology 149: 93-99, 2008.
3e L.M. Flanagan-Cato 10 B.J. Lee, and f7 L.H. Calizo. : Triple labeling analysis of the function and connectivity of progesterone receptor-containing neurons in the hypothalamic ventromedial nucleus of the female rat. Hormones and Behavior 50: 52-60, 2006.
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Selected Publications
37 Ferri, S.L. 57 L.M. Flanagan-Cato. : Oxytocin and dendrite remodeling in the hypothalamus. 41 Hormones and Behavior 61: 251-258, 2012.39 Griffin, G.D. c8 L.M. Flanagan-Cato. : Ovarian hormone action in the hypothalamic ventromedial nucleus: remodelling to regulate reproduction. J. Neuroendocrinology 23: 465-471, 2011.
e1 Flanagan-Cato, L.M. : Sex differences in the neural circuits mediating female sexual receptivity. Frontiers in Neuroendocrinology 32: 124-136, 2011.
16b Griffin, G.D., S.L. Ferri-Kolwicz, B.S. Reyes, E. J. Van Bockstaele and L.M. Flanagan-Cato. : Ovarian hormone-induced reorganization of oxytocin-labeled dendrites and synapses lateral to the hypothalamic ventromedial nucleus in female rats. J. Comparative Neurology 518: 4531-4545, 2010.
11c LaBelle, D.R., J.M. Cox, A.A. Dunn-Meynell, B.E. Levin, and L.M. Flanagan-Cato. : Genetic and dietary effects on dendrites in the hypothalamic ventromedial nucleus. Physiology and Behavior 98: 511-516, 2009.
fc Griffin, G.D. and L.M. Flanagan-Cato. : Sex differences in the dendritic arbors of neurons in the hypothalamic ventromedial nucleus. Physiology and Behavior 97: 151-156, 2009.
142 Griffin, G.D. and L.M. Flanagan-Cato. : Estradiol and progesterone differentially regulate the dendritic arbor of neurons in the hypothalamic ventromedial nucleus of the female rat (Rattus norvegicus). J. Comparative Neurology 510: 631-640, 2008.
e1 Pfaff, D.W., L.-M. Kow, M. Loose, L.M. Flanagan-Cato. : Reverse engineering the lordosis behavior circuit. Hormones and Behavior 55: 347–354, 2008.
113 Flanagan-Cato, L.M., S.J. Fluharty, E.B. Weinreb, and D.R. LaBelle. : Food restriction alters neuronal morphology in the hypothalamic ventromedial nucleus of male rats. Endocrinology 149: 93-99, 2008.
3e L.M. Flanagan-Cato 10 B.J. Lee, and f7 L.H. Calizo. : Triple labeling analysis of the function and connectivity of progesterone receptor-containing neurons in the hypothalamic ventromedial nucleus of the female rat. Hormones and Behavior 50: 52-60, 2006.
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