Louis J. Soslowsky

faculty photo
Fairhill Professor
Department: Orthopaedic Surgery

Contact information
McKay Orthopaedic Research Laboratory
307A Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104-6081
Office: 215-898-8653
Fax: 215-573-2133
Education:
Diploma
East Brunswick High School , 1982.
B.S. (Engineering Mechanics)
Columbia University, 1986.
M.S. (Engineering Mechanics)
Columbia University, 1987.
M.Phil
Columbia University, 1989.
Ph.D. (Engineering Mech./Biomechanics, Mentor: Van C. Mow)
Columbia University, 1991.
Cert. (Academic Medicine Leadership Program)
Wharton School of the University of Pennsylvania , 2008.
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Description of Research Expertise

orthopaedic research, orthopaedic biomechanics and tissue engineering, tendons and ligaments, shoulder and elbow

Selected Publications

Freedman BR, Rodriguez AB, Hillin CD, Weiss SN, Han B, Han L, Soslowsky LJ: Tendon healing affects the multiscale mechanical, structural and compositional response of tendon to quasi-static tensile loading. J R Soc Interface 15(139), 2018.

Sierra LJ, Brown AG, Barilá GO, Anton L, Barnum CE, Shetye SS, Soslowsky LJ, Elovitz MA: Colonization of the cervicovaginal space with Gardnerella vaginalis leads to local inflammation and cervical remodeling in pregnant mice. PLoS One 2018.

Huegel J, Choi DS, Nuss CA, Minnig MCC, Tucker JJ, Kuntz AF, Waldorff EI, Zhang N, Ryaby JT, Soslowsky LJ: Effects of pulsed electromagnetic field therapy at different frequencies and durations on rotator cuff tendon-to-bone healing in a rat model. J Shoulder Elbow Surg Page: 553-60 2018.

Zhang K, Hast MW, Izumi S, Usami Y, Shetye S, Akabudike N, Philp NJ, Iwamoto M, Nissim I, Soslowsky LJ, Enomoto-Iwamoto M: Modulating Glucose Metabolism and Lactate Synthesis in Injured Mouse Tendons: Treatment With Dichloroacetate, a Lactate Synthesis Inhibitor, Improves Tendon Healing. Am J Sports Med 46(9): 2222-31, 2018.

Freedman BR, Rodriguez AB, Leiphart RJ, Newton JB, Ban E, Sarver JJ, Mauck RL, Shenoy VB, Soslowsky LJ: Dynamic Loading and Tendon Healing Affect Multiscale Tendon Properties and ECM Stress Transmission. Sci Rep 8(1): 10854, 2018.

Barnum CE, Fey JL, Weiss SN, Barila G, Brown AG, Connizzo BK, Shetye SS, Elovitz MA, Soslowsky LJ: Tensile Mechanical Properties and Dynamic Collagen Fiber Re-Alignment of the Murine Cervix are Dramatically Altered Throughout Pregnancy. J Biomechan Eng 139(6), 2017.

Robinson KA, Sun M, Barnum CE, Weiss SN, Huegel J, Shetye SS, Lin L, Saez D, Adams SM, Iozzo RV, Soslowsky LJ, Birk DE: Decorin and biglycan are necessary for maintaining collagen fibril structure, fiber realignment, and mechanical properties of mature tendons. Matrix Biol Page: 81-93, 2017.

Patel S, Caldwell JM, Doty SB, Levine WN, Rodeo S, Soslowsky LJ, Thomopoulos S, Lu HH: Integrating soft and hard tissues via interface tissue engineering. J Orthop Res 2017.

Taylor B, Cheema A, Soslowsky L: Tendon Pathology in Hypercholesterolemia and Familial Hypercholesterolemia. Curr Rheumatol Rep 2017.

Freedman BR, Salka NS, Morris TR, Bhatt PR, Pardes AM, Gordon JA, Nuss CA, Riggin CN, Fryhofer GW, Farber DC, Soslowsky L: Temporal Healing of Achilles Tendons After Injury in Rodents Depends on Surgical Treatment and Activity. J Am Acad Orthop Surg Page: 635-47, 2017.

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Last updated: 03/26/2019
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