Welcome to McKay Orthopaedic Research Laboratory

A program in orthopaedic research at the University of Pennsylvania was established in 1960, and in 1979 the McKay Orthopaedic Research Laboratory officially opened, establishing all of the orthopaedic research laboratories in the same physical location. Currently, the McKay Lab is a thriving, multidisciplinary facility that occupies more than 22,000 square feet of space in Stemmler Hall in the Perelman School of Medicine. Our multi-faceted research programs involve the participation of more than 120 research personnel from 17 distinct laboratories. Research expenditures in McKay total more than $15,000,000 per annum, supported largely through extramural funding including grants from the National Institutes of Health, Veteran's Administration, other governmental agencies, private foundations, and industry. We are consistently ranked in the top 5 among Orthopaedic Departments nationally in terms of NIH funding. Our overall mission is to conduct high quality fundamental and translational research and to train the next generation of leaders in our field. Moreover, the McKay Lab serves as the focal point for the NIH-supported Penn Center for Musculoskeletal Disorders, a university-wide Center that provides resources and a forum for scientific exchange through annual symposia, a year-long seminar series, a pilot grant program and other activities. 

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McKay Laboratory News

Congratulations to Dr. Zakary Beach, Courtney Nuss, Stephanie Weiss, and Dr. Soslwosky!
November 22, 2023
Congratulations to Zak, Courtney, Steph, and Dr. Soslowsky for their manuscript, "Neonatal Achilles Tendon Microstructure is Negatively Impacted by Decorin and Biglycan Knockdown After Injury and During Development" accepted for publication in the Annals of Biomedical Engineering!
Soslowsky Laboratory

Congratulations to Dr. Jaclyn Carlson, Snehal Shetye, Mei Sun, Stephanie Weiss, Dr. Birk, and Dr. Soslowsky
November 16, 2023
Congratulations to Jackie, Snehal, Mei, Steph, Dr. Birk, and Dr. Soslwosky for their manuscript "Collagen V haploinsufficiency in female murine patellar tendons results in altered matrix engagement and cellular density, demonstrating decreased healing" accepted for publication in the Journal of Orthopaedic Research!
Soslowsky Laboratory

Congratulations to Dr. Ana Peredo and Coauthors for New STM Cover
November 15, 2023
Congratulations to Dr. Ana Peredo and coauthors on their latest publication "Tension-activated nanofiber patches delivering an anti-inflammatory drug improve repair in a goat intervertebral disc herniation model." Their work was also featured as the cover of Science Translational Medicine's latest issue!
Mauck LaboratoryGullbrand Laboratory

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Congratulations to the new Penn Medicine Achilles Tendon Research Center and the Center founding Director Dr. Lou Soslowsky.  See article at Penn Medicine News

February 7, 2023 - Penn Almanac Press Release

Congratulations to the McKay Orthopaedic Research Laboratory for being Ranked #1 in 2021 for NIH Funding. See article at Penn Medicine News

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