McKay Orthopaedic Research Laboratory

October 18, 2013

Ben Freedman and Cori Riggin: Dallaudiere et al. (2013) "Acceleration of tendon healing using US guided intratendinous injection of bevacizumab: First pre-clinical study on a murine model" Eur J Radiol (Published online ahead of print). Biercevicz et al. (2013) "In Situ, Noninvasive, T2*-Weighted MRI-Derived Parameters Predict Ex Vivo Structural Properties of an Anterior Cruciate Ligament Reconstruction or Bioenhanced Primary Repair in a Porcine Model" Am J Sports Med 41:560-566.

September 20, 2013

Mike Hast and Andrey Zuskov: Yamazaki et al. (2013) "Assessment of pain-related behavior and pro-inflammatory cytokine levels in the rat rotator cuff tear model" J Orthop Res (Published online ahead of print). Zhang et al. (2012) "The effects of Dexamethasone on human patellar tendon stem cells: Implications for Dexamethasone treatment of tendon injury" J Orthop Res 31:105-110.

July 19, 2013

Lis Evans and Sarah Ilkhani-Pour: Elsaid et al. (2012) "The impact of forced joint exercise on lubricin biosynthesis from articular cartilage following ACL transection and intra-articular lubricin’s effect in exercised joints following ACL transection" Osteoarthritis and Cartilage 20:940-948. Pingel et al. (2013) "No inflammatory gene-expression response to acute exercise in human Achilles tendinopathy" Eur J Appl Physiol (Published online 16 April)

May 24, 2013

Adam Caro and Sarah Yannascoli: Friel et al. (2013) "Rotator cuff healing after continuous subacromial bupivacaine infusion: an in vivo rabbit study" J Shoulder Elbow Surg 22: 489-499. Cacao-Benedini et al. (2012) "Remobilization through stretching improves gait recovery in the rat" Acta Histochemica (Published online ahead of print).

March 29, 2013

Bri Connizzo and Steve Thomas: Rigozzi et al. (2013), "Tendon glycosaminoglycan proteoglycan sidechains promote collagen fibril sliding- AFM observations at the nanoscale" J Biomech 46:813-818. Attia et al. (2013), "Early Events of Overused Supraspinatus Tendons Involve Matrix Metalloproteinases and EMMPRIN/CD147 in the Absense of Inflammation" Am J Sports Med (Published online ahead of print).

March 1, 2013

Mike Hast and Jennica Tucker: Millard et al. (2013), "Flexing Computational Muscle: Modeling and Simulation of Musculotendon Dynamics" J Biomech Eng 135:021004-1-11. Gumucio et al. (2012), "Rotator Cuff Tear Reduces Muscle Fiber Specific Force Production and Induces Macrophage Accumulation and Autophagy" J Orthop Res 30:1963-70.

Januray 11, 2013

Elisabeth Evans and Benjamin Freedman: Medias et al. (2012), "Mechanical loading and TGF-β change the expression of multiple miRNAs in tendon fibroblasts" J Appl Physiol 113:56-62. Veres et al. (2012), "Repeated Subrupture Overload Causes Progression of Nanoscaled Descrete Plasticity Damage in Tendon Collagen Fibrils" J Orthop Res (Published online ahead of print).

December 7, 2012

Adam Caro and Cori Riggin: Buchmann et al. (2012), "Refixation of the Supraspinatus Tendon in a Rat Model--Influence of Continuous Growth Factor Application on Tendon Structure" J Orthop Res, (Published online ahead of print). Chamberlain et al. (2012), "Temporal Healing in Rat Achilles Tendon: Ultrasound Correlations" Ann Biomed Eng (Published online ahead of print).

October 26, 2012

Katie Reuther and Sarah Yannascoli: Samagh et al. (2012), "MRI Quantification of Fatty Infiltration and Muscle Atrophy in a Mouse Model of Rotator Cuff Tears" J Orthop Res, (Published online ahead of print). Cuff et al. (2012), "Prospective randomized study of arthroscopic rotator cuff repair using an early versus delayed postoperative physical therapy protocol" J Shoulder Elbow Surg 21:1450-55.

September 21, 2012

Bri Connizzo and Sarah Ilkhani-Pour: Watanabe et al. (2012), "Concerted and adaptive alignment of decorin dermatan sulfate filaments in the graded organization of collagen fibrils in the equine superficial digital flexor tendon" J Anat, 220:156-63. Andersson et al. (2012), "Low level mechanical stimulation is sufficient to improve tendon healing in rats" J Appl Physiol (Published online ahead of print).

August 10, 2012

Steve Thomas and Jennica Tucker: Kaux et al. (2012), "Eccentric training improves tendon biomechanical properties: A rat model" J Orthop Res (Published online before print). Heinemeier et al. (2012), "Uphill running improves rat Achilles tendon tissue mechanical properties, and alters gene expression without inducing pathological changes" J Appl Physiol (Published online ahead of print).

July 13, 2012

Mike Hast and Mark Buckley: Andarawis-Puri et al. (2012), "Molecular response of the patellar tendon to fatigue loading explained in the context of the initial induced damage and number of fatigue loading cycles" J Orthop Res 30:1327-1334. Svensson et al. (2012), "Mechanical properties of human patellar tendon at the hierarchical levels of tendon and fibril" J Appl Physiol 112:419-426.

June 8, 2012

Pramod Voleti and Ben Freedman: Keating and Will (2011), "Operative versus non-operative treatment of acute rupture of tendo Achillis" J Bone Joint Surg Br 93:1071-78. 
Sereysky et al. (2012), "Structural and Mechanical Effects of In Vivo Fatigue Damage Induction on Murine Tendon" J Orthop Res 30:965-72.

May 11, 2012

Cori Riggin and J Sarver: Duenwald-Kuehl et al. (2012), "Strain-induced damage reduces echo intensity changes in tendon during loading" J Biomech (Published online before print.) Beckett et al. (2012), "Excessive Running Induces Cartilage Degeneration in Knee Joints and Alters Gait of Rats" J Orthop Res (Published online before print.)

April 13, 2012

Katie Reuther and Bri Connizzo: Carroll et al. (2012), "The influence of acetaminophen consumption and exercise on Achilles tendon structural properties in male Wistar rats" Am J Physiol Regul Integr Comp Physiol (Published online before print) Duenwald-Kuehl et al. (2012), "Damage mechanics of porcine flexor tendon: Mechanical evaluation and modeling" Ann Biomed Eng (Published online before print.)

March 16, 2012

Mark Buckley and Sarah Ilkhani-Pour: Rigozzi et al. (2011), "Mechanical response of individual collagen fibrils in loaded tendon as measured by atomic force microscopy" J Struct Biol 176:9-15. Buchmann et al. (2011), "Rotator cuff changes in a full thickness tear rat model: verification of the optimal time interval until reconstruction for comparison to the healing process of chronic lesions in humans" Arch Orthop Trauma Surg 131:429-35.

January 13, 2012

Steve Thomas and Jennica Tucker: Mannava et al. (2011), "Evaluation of in vivo rotator cuff muscle function after acute and chronic detachment of the supraspinatus tendon: an experimental study in an animal model" J Bone Joint Surg Am 93:1702-11. 
Su et al. (2011), "Posterosuperior displacement due to rotator cuff tears" Arthroscopy 27:1472-7.

December 16, 2011

Lauren Satchell and Pramod Voleti: Lakemeier et al. (2010), "Expression of matrix metalloproteinases 1, 3, and 9 in degenerated long head biceps tendon in the presence of rotator cuff tears: an immunohistological study" BMC Musculoskelet Disord 11:271. Eliasson et al. (2012), "Achilles tendon healing in rats is improved by intermittent mechanical loading during the inflammatory phase" J Orthop Res, in press.

November 11, 2011

Kristin Miller and Katie Reuther: Liu et al. (2012), "Spatial and temporal expression of molecular markers and cell signals during normal development of the mouse patellar tendon" Tissue Eng Part A, in press. Shindle et al. (2012), "Full-thickness supraspinatus tears are associated with more synovial inflammation and tissue degeneration than partial-thickness tears" J Shoulder Elbow Surg, in press.

September 16, 2011

David Beason and J Sarver: Maeda et al. (2011), "Conversion of Mechanical Force into TGF-β-Mediated Biochemical Signals" Curr Biol 21:933-41. Ng et al. (2011), "Enforced Bipedal Downhill Running Induces Achilles Tendinosis in Rats" Connect Tissue Res, in press.

April 1, 2011

Bri Connizzo and Sarah Ilkhani-Pour: Kishore et al. (2011), "Incorporation of a decorin biomimetic enhances the mechanical properties 3 of electrochemically aligned collagen threads" Acta Biomater, in press. Duenwald et al. (2011), "Ultrasound echo is related to stress and strain in tendon" J Biomech 44:424-9.

March 18, 2011

Mark Buckley and Lydia Pathmanathan: Svensson et al. (2010), "Tensile Properties of Human Collagen Fibrils and Fascicles Are Insensitive to Environmental Salts" Biophys J 99:4020-7. Scott et al. (2011), "Scleraxis Expression Is Coordinately Regulated in a Murine Model of Patellar Tendon Injury" J Orthop Res 29:289-96.

February 11, 2011

Chance Gray and Jennica Tucker:
Andersson et al. (2011), "Tenocyte hypercellularity and vascular proliferation in a rabbit model of tendinopathy: contralateral effects suggest the involvement of central neuronal mechanisms" Br J Sports Med, in press. 
Poulet et al. (2011), "Characterizing a novel and adjustable noninvasive murine joint loading model" Arthritis Rheum 63:137-47.

November 19, 2010

LeAnn Dourte and Chang Soo Lee:
Henninger et al. (2010), "Effect of sulfated glycosaminoglycan digestion on the transverse permeability of medial collateral ligament" J Biomech 43:2567-73. 
Kanno et al. (2010), "Development of a Shoulder Contracture Model in Rats" J Shoulder Elbow Surg 19:700-8.

October 15, 2010

Katie Reuther and Steve Thomas:
Bedi et al. (2010), "The effect of matrix metalloproteinase inhibition on tendon-to-bone healing in a rotator cuff repair model" J Shoulder Elbow Surg 19:384-91. 
Nourissat et al. (2010), "Mesenchymal Stem Cell Therapy Regenerates the Native Bone-Tendon Junction after Surgical Repair in a Degenerative Rat Model" PLoS One 5:e12248.

May 14, 2010

Lena Edelstein and Jason Hsu:
Komolafe and Doehring (2010), "Fascicle-Scale Loading and Failure Behavior of the Achilles Tendon" J Biomech Eng 132:021004. 
Sun et al. (2010), "Cycle-Dependent Matrix Remodeling Gene Expression Response in Fatigue-Loaded Rat Patellar Tendons" J Orthop Res, in press.

April 9, 2010

David Beason and J Sarver: 
Reddy (2003), "Glucose-mediated in vitro glycation modulates biomechanical integrity of soft tissues but not hard tissues" J Orthop Res, 21:738-43. 
Bedi et al. (2010), "Diabetes mellitus impairs tendon-bone healing after rotator cuff repair" J Shoulder Elbow Surg, in press.

February 19, 2010

Kristin Miller and Spence Szczesny: 
Hu et al. (2009), "Characterization of engineered tissue development under biaxial stretch using nonlinear optical microscopy" Tissue Eng Part A, 15:1553-64. 
Cadet et al. (2010), "Improving bone density at the rotator cuff footprint increases supraspinatus tendon failure stress in a rat model" J Orthop Res, in press.

January 22, 2010

Heather Ansorge and Daniel Cortes: 
Mikic et al. (2010), "Sex matters in the establishment of murine tendon composition and material properties during growth" J Orthop Res, in press. 
Fessel and Snedeker (2009), "Evidence against proteoglycan mediated collagen fibril load transmission and dynamic viscoelasticity in tendon" Matrix Biol, 28:503-10.

November 6, 2009

Lena Edelstein and Jason Hsu: 
Gulotta et al. (2009), "Application of Bone Marrow-Derived Mesenchymal Stem Cells in a Rotator Cuff Repair Model" Am J Sports Med, in press. 
Galatz et al. (2009), "Complete removal of load is detrimental to rotator cuff healing" J Shoulder Elbow Surg, 18:669-75.

October 16, 2009

LeAnn Dourte and Kristin Miller: 
Brink et al. (2009), "Fetal dermal fibroblasts exhibit enhanced growth and collagen production in two- and three-dimensional culture in comparison to adult fibroblasts" J Tissue Eng Regen Med, in press. 
Jhun et al. (2009), "Planar biaxial mechanical behavior of bioartificial tissues possessing prescribed fiber alignment" J Biomech Eng, 131:081006.

September 25, 2019

Cathy Peltz and Spence Szczesny: 
Keener et al. (2009), "Proximal Humeral Migration in Shoulder with Symptomatic and Asymptomatic Rotator Cuff Tears" J Bone Joint Surg Am, 91:1405-13. 
Cousineau-Pelletier and Langelier (2009), "Relative Contributions of Mechanical Degradation, Enzymatic Degradation, and Repair of the Extracellular Matrix on the Response of Tendons When Subjected to Under- and Over- Mechanical Stimulations In Vitro" J Orthop Res, in press.

April 13, 2009

Heather Ansorge and Kristin Miller: 
Pearse et al. (2009), "Genome-Wide Expression Analysis of Intra- and Extraarticular Connective Tissue" J Orthop Res, 27(4):427-34. 
Yang et al. (2009), "Biomechanical analysis of bursal-sided partial thickness rotator cuff tears" J Shoulder Elbow Surg,in press.

March 9, 2009

David Beason and Mike Dishowitz: 
Nirmalanandhan et al. (2009), "Combined Effects of Scaffold Stiffening and Mechanical Preconditioning Cycles on Construct Biomechanics, Gene Expression, and Tendon Repair Biomechanics" Tissue Eng Part A, in press. 
Spalazzi et al. (2008), "In vivo evaluation of a multiphased scaffold designed for orthopaedic interface tissue engineering and soft tissue-to-bone integration" J Biomed Mater Res A, 86(1):1-12.

February 16, 2009

Cathy Peltz and Spence Szczesny: 
Singaraju et al. (2008), "Biceps tendinitis in chronic rotator cuff tears: A histologic perspective" J Shoulder Elbow Surg, 17(6):898-904. 
Rainis et al. (2009), "Material Properties of the Axillary Pouch of the Glenohumeral Capsule: Is Isotropic Material Symmetry Appropriate?" J Biomech Eng, 131(3):in press.

January 12, 2009

Spence Lake and J Sarver: 
DeFrate et al. (2006), "The measurement of the variation in the surface strains of Achilles tendon grafts using imaging techniques" J Biomech, 39(3):399-405. 
Couppé et al. (2008), "Habitual loading results in tendon hypertrophy and increased stiffness of the human patellar tendon" J Appl Physiol, 105(3):805-10.

December 8, 2008

Heather Ansorge and Kristin Miller: 
Hasslund et al. (2008), "Adhesions in a Murine Flexor Tendon Graft Model: Autograft versus Allograft Reconstruction" J Orthop Res, 26(6):824-33. 
Nirmalanandhan et al. (2007), "Effect of length of the engineered tendon construct on its structure–function relationships in culture" J Biomech, 40(11):2523-9.

November 10, 2008

Cathy Peltz and Milt Zgonis: 
Fung et al. (2008), "Subrupture Tendon Fatigue Damage" J Orthop Res, in press. 
Thomopoulos et al. (2007), "PDGF-BB Released in Tendon Repair Using a Novel Delivery System Promotes Cell Proliferation and Collagen Remodeling" J Orthop Res, 25(10):1358-68.

October 13, 2008

David Beason and LeAnn Dourte: 
Bolt et al. (2007), "BMP-14 Gene Therapy Increases Tendon Tensile Strength in a Rat Model of Achilles Tendon Injury" J Bone Joint Surg Am, 89(6):1315-20. 
Abreu et al. (2008), "Effect of Altered Mechanical Load Conditions on the Structure and Function of Cultured Tendon Fascicles" J Orthop Res, 26(3):364-73.

September 15, 2008

Mike Dishowitz and J Sarver: 
Thomopoulos et al. (2008), "The Effect of Muscle Loading on Flexor Tendon-to-Bone Healing in a Canine Model" J Orthop Res, in press. 
Sundar et al. (2008), "Tendon bone healing can be enhanced by demineralized bone matrix: A functional and histological study" J Biomed Mater Res B Appl Biomater, in press.

May 2, 2008

Mike Dishowitz and LeAnn Dourte: 
Joshi and Webb (2008), "Variation of Cyclic Strain Parameters Regulates Development of Elastic Modulus in Fibroblast/Substrate Constructs" J Orthop Res, in press. 
Galatz et al. (2007), "Development of the Supraspinatus Tendon-to-Bone Insertion: Localized Expression of Extracellular Matrix and Growth Factor Genes" J Orthop Res, 25(12):1621-8.

April 4, 2008

Nelly Andarawis and Heather Ansorge: 
Lujan et al. (2007), "Effect of ACL Deficiency on MCL Strains and Joint Kinematics" J Biomech Eng, 129(3):386-92. 
Miyatake et al. (2008), "Local Administration of Interleukin-1 Receptor Antagonist Inhibits Deterioration of Mechanical Properties of the Stress-Shielded Patellar Ttendon" J Biomech, 41(4):884-9.

February 1, 2008

David Beason and Spence Lake: 
Shearn et al. (2007), "Mechanical Stimulation of Tendon Tissue Engineered Constructs: Effects on Construct Stiffness, Repair Biomechanics, and Their Correlation" J Biomech Eng, 129(6):848-54. 
Thomopoulos et al. (2007), "Collagen Fiber Alignment Does Not Explain Mechanical Anisotropy in Fibroblast Populated Collagen Gels" J Biomech Eng, 129(5):642-50.

November 30, 2007

Andy Kuntz and Cathy Peltz: 
Large et al. (2007), "A Biomechanical Comparison of 2 Ulnar Collateral Ligament Reconstruction Techniques" Arthroscopy 23(2):141-50. 
Silva et al. (2006), "Early Healing of Flexor Tendon Insertion Site Injuries: Tunnel Repair Is Mechanically and Histologically Inferior to Surface Repair in a Canine Model" J Orthop Res, 24(5):990-1000.

October 19, 2007

David Glaser and Steph Perry: 
Walton et al. (2007), "Restore Orthobiologic Implant: Not Recommended for Augmentation of Rotator Cuff Repairs" J Bone Joint Surg Am 89:786-91. 
Schlegel et al. (2006), "The Effects of Augmentation With Swine Small Intestine Submucosa on Tendon Healing Under Tension: Histologic and Mechanical Evaluations in Sheep" Am J Sports Med, 34(2):275-80.

March 28, 2007

Cathy Peltz and Jen Kadlowec: 
Hatakeyama et al. (2001), "Effect of Arm Elevation and Rotation on the Strain in the Repaired Rotator Cuff Tendon: A Cadaveric Study" Am J Sports Med 29:788-94. 
Gladstone et al. (2007), "Fatty Infiltration and Atrophy of the Rotator Cuff Do Not Improve After Rotator Cuff Repair and Correlate With Poor Functional Outcome" Am J Sports Med, in press.

February 28, 2007

J Sarver and Jason Zappacosta: 
Werner et al. (2006), "The biomechanical role of the subscapularis in latissimus dorsi transfer for the treatment of irreparable rotator cuff tears" J Shoulder Elbow Surg 15:736-42. 
Yamamoto et al. (2006), "Why is the humeral retroversion of throwing athletes greater in dominant shoulders than in nondominant shoulders?" J Shoulder Elbow Surg 15:571-5.

February 7, 2007

Jon Van Kleunen and Mike Dishowitz: 
Chong et al. (2007), "Bone Marrow-Derived Mesenchymal Stem Cells Influence Early Tendon-Healing in a Rabbit Achilles Tendon Model" J Bone Joint Surg 89-A(1):74-81. 
Fu et al. (2006), "Enhanced wound-healing quality with bone marrow mesenchymal stem cells autografting after skin injury" Wound Repair Regen 14(3):325-35.

December 6, 2006

Nelly Andarawis and Steph Perry:
Parsons et al. (2002), "The effect of rotator cuff tears on reaction forces at the glenohumeral joint" J Orthop Res 20:439-46. 
Iannotti et al. (1996), "Postoperative assessment of shoulder function: A prospective study of full-thickness rotator cuff tears" J Shoulder Elbow Surg 5:449-57.

November 8, 2006

Spence Lake and David Beason: 
Tower et al. (2002), "Fiber Alignment Imaging During Mechanical Testing of Soft Tissues" Ann Biomed Eng 30(10):1221-33. 
Sacks et al. (1997), "A Small Angle Light Scattering Device for Planar Connective Tissue Microstructural Analysis" Ann Biomed Eng 25(4):678-89.

October 11, 2006

Heather Ansorge and LeAnn Dourte: 
Molloy et al. (2006), "Microarray Analysis of Healing Rat Achilles Tendon: Evidence for Glutamate Signaling Mechanisms and Embryonic Gene Expression in Healing Tendon Tissue" J Orthop Res 24:842-55. 
Blaine et al. (2005), "The molecular pathophysiology of subacromial bursitis in rotator cuff disease" J Shoulder Elbow Surg 14:84S-89S.

June 14, 2006

David Beason and Eric Ricchetti: 
Alaseirlis et al. (2005), "Decreasing Inflammatory Response of Injured Patellar Tendons Results in Increased Collagen Fibril Diameters" Connect Tissue Res 46:12-7. 
Kobayashi et al. (2006), "Expression of growth factors in the early phase of supraspinatus tendon healing in rabbits" J Shoulder Elbow Surg 15: 371-7.

May 25, 2006

Michele Favata and Milt Zgonis: 
Juncosa-Melvin et al. (2006), "The Effect of Autologous Mesenchymal Stem Cells on the Biomechanics and Histology of Gel-Collagen Sponge Constructs Used for Rabbit Patellar Tendon Repair" Tissue Eng 12(2):369-79. 
Voloshin et al. (2005), "Proinflammatory Cytokines and Metalloproteases Are Expressed in the Subacromial Bursa in Patients With Rotator Cuff Disease" Arthroscopy 21(9):1076.e1-1076.e9.

April 26, 2006

Steph Perry and Cathy Peltz: 
Crawford and Sauers (2006), "Glenohumeral joint laxity and stiffness in the functional throwing position of high school baseball pitchers" J Athl Train 41(1):52-9. 
Borsa et al. (2005), "Correlation of range of motion and glenohumeral translation in professional baseball pitchers" Am J Sports Med 33(9):1392-9.

February 22, 2006

Nelly Andarawis and LeAnn Dourte: 
Hansen et al. (2006), "Mechanical properties of the human patellar tendon, in vivo" Clin Biomech (Bristol, Avon) 21(1):54-8. 
Drace and Pelc (1994), "Elastic deformation in tendons and myotendinous tissue: measurement by phase-contrast MR imaging" Radiology 191(3):835-9.

January 17, 2006

Wade Johannessen: 
Tsantrizos et al. (2005), "Internal strains in healthy and degenerated lumbar intervertebral discs" Spine 30(19):2129-37.

December 14, 2005

Eric Ricchetti and David Beason: 
Massy-Westropp et al. (2004), "Measuring grip strength in normal adults: reference ranges and a comparison of electronic and hydraulic instruments" J Hand Surg[Am] 29(3):514-9. 
Lehtinen et al. (2003), "Practical assessment of rotator cuff muscle volumes using shoulder MRI" Acta Orthop Scand 74(6):722-9.

November 4, 2005

Steve Nicoll: 
Wang et al. (2003), "Cyclic Mechanical Stretching of Human Tendon Fibroblasts Increases the Production of Prostaglandin E2 and Levels of Cyclooxygenase Expression: A Novel In Vitro Model Study Connective Tissue Research" 44:128-33.

October 7, 2005

Jason Burdick: 
Elisseeff et al. (2000), "Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi-interpenetrating networks" J Biomed Mater Res 51:164-71.

September 1, 2005

Wade Johannessen: 
Benneker et al. (2005), "2004 Young Investigator Award Winner: vertebral endplate marrow contact channel occlusions and intervertebral disc degeneration" Spine 30(2):167-73.

August 15, 2005

Grace O'Connell: 
Kroeber et al. (2005), "Effects of controlled dynamic disc distraction on degenerated intervertebral discs: an in vivo study on the rabbit lumbar spine model" Spine 30(2):181-7.

July 18, 2005

Heather Ansorge and Cathy Peltz: 
Li et al. (2005), "A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells" Biomaterials 26(6):599-609. 
Deitzel et al. (2001), "The effect of processing variables on the morphology of electrospun nanofibers and textiles" Polymer 42:261-72.

June 23, 2005

Spence Lake and Sudheer Reddy: 
Martinek et al. (2002), "Enhancement of tendon-bone integration of anterior cruciate ligament grafts with bone morphogenetic protein-2 gene transfer" J Bone Joint Surg 84(A):1123-31. 
Lou et al. (2001), "BMP-12 gene transfer augmentation of lacerated tendon repair" J Orthop Res 19:1199-1202.

May 16, 2005

David Beason and Milt Zgonis: 
Lavagnino et al. (2003), "Effect of amplitude and frequency of cyclic tensile strain on the inhibition of MMP-1 mRNA expression in tendon cells: an in vitro study" Connect Tissue Res 44(3-4):181-7. 
Lavagnino et al. (2005), "Collagen fibril diameter distribution does not reflect changes in the mechanical properties of in vitro stress-deprived tendons" J Biomech 38(1):69-75.

April 5, 2005

Jesse Beckstein and Alykhan Kurji: 
Masuda et al. (2004), "Growth Factors and Treatment of Intervertebral Disc Degeneration" Spine 29(23):2757-69. 
Shimer et al. (2004), "Gene Therapy Approaches for intervertebral Disc Degeneration" Spine 29(23):2770-8.

March 21, 2005

Michele Favata and Steph Perry: 
Uchida et al. (2005), "Stress deprivation simultaneously induces over-expression of inter-leukin-1beta, tumor necrosis factor-alpha, and transforming growth factor beta in fibroblasts and mechanical deterioration of the tissue in the patellar tendon" J Biomech 38:791-8. 
Riley et al. (2002), "Matrix metalloproteinase activities and their relationship with collagen remodelling in tendon pathology" Matrix Biol 21:185-95.

February 1, 2005

Cindy Chung and Annie Reza: 
Mizuno et al. (2004), "Tissue-engineered composites of anulus fibrosus and nucleus pulposus for intervertebral disc replacement" Spine 29:1290-8. 
Wong et al. (2003), "Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertrophic markers in primary chondrocytes" Bone 33:685-93.

January 24, 2005

Heather Ansorge and Cathy Peltz: 
Chen et al. (2004), "Extracorpreal shock waves promote healing of collagenase-induced Achilles tendonitis and increase TGF-B1 and IGF-1 expression" J Orthop Res 22:854-61. 
Hsu et al. (2004), "Effect of shock-wave therapy on patellar tendinopathy in a rabbit model" J Orthop Res 22:221-7.

December 8, 2004

Ehren Carine and Kyle Quinn: 
Battie et al. (2004), "Lumbar disc degeneration" Spine 29(23):2679-90. 
Urban et al. (2004), "Nutrition of the Intervertebral Disc" Spine 29(23):2700-9.

November 20, 2004

John Boxberger and Steph Perry: 
Riggs (2002), "Fractures - A Preventable Hazard of Racing Thoroughbreds?" Vet J 163:19-29. 
Donahue et al. (2000), "Bone Strain and Microcracks at Stress Fracture Sites in Human Metatarsals" Bone 27(6):827-33.

October 20, 2004

Spence Lake and Milt Zgonis: 
West et al. (2004), "Characterization of in vivo Achilles tendon forces in rabbits during treadmill locomotion at varying speeds and inclinations" J Biomech 37:1647-53. 
Meyer et al. (2004), "A pathomechanical concept explains muscle loss and fatty muscular changes following surgical tendon release" J Orthop Res 22:1004-7.

September 2, 2004

Michele Favata and Heather Lynch: 
Arnoczky et al. (2004), "Ex Vivo Static Tensile Loading Inhibits MMP-1 Expression in Rat Tail Tendon Cells Through a Cytoskeletally Based Mechanotransduction Mechanism" J Orthop Res 22:328-33. 
Trickey et al. (2004), "The Role of the Cytoskeleton in the Viscoelastic Properties of Human Articular Chondrocytes" J Orthop Res 22:131-9.

June 10, 2004

Hallie Brink and Alice Chou: 
Alini et al. (2003), "The Potential and Limitations of a Cell-Seeded Collagen/Hyaluronan Scaffold to Engineer an Intervertebral Disc-Like Matrix" Spine 28(5):446-54. 
Altman et al. (2001), "Cell Differentiation by Mechanical Stress" FASEB Journal. online December 28, 2001.

May 6, 2004

Charlie Hee and Greg Miller: 
Kasra et al. (2003), "Effect of dynamic hydrostatic pressure on rabbit intervertebral disc cells" J Orthop Res 21:597-603. 
Van Gaalen et al. (2004), "Bone tissue engineering for spine fusion: an experimental study on ectopic and orthotopic implants in rats" Tissue Eng 10(1/2):231-9.

March 4, 2004

John Boxberger and Spence Lake: 
Yamamoto et al. (2003), "Effects of cyclic stress on the mechanical perperties of cultered collagen fascicles from the rabbit patellar tendon" J Biomech Eng 125:893-901. 
Hannafin et al. (1995), "Effect of stress deprivation and cylclic tensile laoding on the material and morphologic properties of canine flexor digitorum profundus tendon: An in vitro study" J Orthop Res 13:907-14.

February 5, 2004

Nelly Andarawis and Simone Stalling: 
Musahl et al. (2004), "The use of porcine small intestinal submucosa to enhance the healing of the medial collateral ligament--a functional tissue engineering study in rabbits" J Orthop Res 22(1):214-20. 
Meaney Murray et al. (2003), "The effect of selected growth factors on human anterior cruciate ligament cell interactions with a three-dimensional collagen-GAG scaffold" J Orthop Res 21(2):238-44.

January 22, 2004

Steph Perry and Jon Van Kleunen: 
Perry et al. (1995), "The effects of anabolic steroids on rat tendon an ultrastructural, biomechanical and biochemical analysis" Am J Sports Med 23(2):227-32. 
Almekinders et al. (1995), "An in vitro investigation into the effects of repetitive motion and nosteroidal anti-inflammatory medication on human tendon fibroblasts" Am J Sports Med 23:119-23.

November 20, 2003

Wade Johannessen and Chandra Yerramalli: 
Wilke et al. (1999), "New in vivo measurements of pressures in the intervertebral disc in daily life" Spine 24:755-62. 
Ledet et al. (2000), "Real-time in vivo loading in the lumbar spine - Part 1. Interbody implant: Load cell design and preliminary results" Spine 25(20):2595-600.

October 16, 2003

Jon Gimbel and J Sarver: 
Murrell et al. (1994), "Effect of immobilization on achilles tendon healing in a rat model" J Orthop Res 12(4):582-90. 
Jozsa et al. (1990), "The effect of tenotomy and immobilization on itramuscular connective tissue: A morphometric and microscopic study in rat calf muscles" J Bone Joint Surg 72-B(2):293-7.

June 19, 2003

Alice Chou and Chandra Yerramalli: 
Sato et al. (2003), "An experimental study of the regeneration of the intervertebral disc with an allograft of cultured annulus fibrosus cells using a tissue-engineering method" Spine 28(6):548-53. 
Norcross et al. (2003), "An in vivo model of degenerative disc disease" J Orthop Res 21(1):183-8.

May 22, 2003

Nelly Andarawis and Charlie Hee: 
Chen et al. (2003), "Matrix fixed-charge density as determined by magnetic resonance microscopy of bioreactor-derived hyaline cartilage correlates with biochemical and biomechanical properties" Arthritis Rheum 48:1047-56. 
Legare et al. (2002), "Detection and analysis of cartilage degeneration by spatially resolved streaming potentials" J Orthop Res 20:819-26.

April 17, 2003

Hallie Brink and Michele Favata: 
Hsieh et al. (2000), "Time-dependent increases in type-III collagen gene expression in medical collateral ligament fibroblasts under cyclic strains" J Orthop Res 18(2):220-7. 
Arnoczky et al. (2002), "In situ cell nucleus deformation in tendons under tensile load; a morphological analysis using confocal laser microscopy" J Orthop Res 20(1):29-35.

March 20, 2003

Jeff Cartmell and Tony Lin: 
Drzewiecki et al. (1991), "Usefulness of a new technique for hind limb immobilization in rats for the study of tendon healing. Arch Orthop Trauma Surg 111:39-42. 
Palms et al. (2002), "Achilles tendon healing: Long-term biomechanical effects of postoperative mobilization and immobilization in a new mouse model" J Orthop Res 20:939-46.

February 20, 2003

Steph Perry and Jon Van Kleunen: 
Tillander et al. (2002), "Fibronectin, MMP-1 and histologic changes in rotator cuff disease" J Orthop Res 20(6):1358-64. 
Yuan et al. (2002), "Apoptosis in rotator cuff tendonopathy" J Orthop Res 20(6):1372-9.

December 19, 2002

Greg Miller and Paul Robinson: 
Jepsen et al. (2002), "A syndrome of joint laxity and impaired tendon integrity in lumican- and fibromodulin-deficient mice" J Biol Chem 277(38):35532-40. 
Mikic et al. (2001), "GDF-5 deficiency in mice alters the ultrastructure, mechanical properties, and composition of the Achilles tendon" J Orthop Res 19(3):365-71.

November 14, 2002

Wade Johannessen and Heather Lynch: 
Nishida et al. (1999), "Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: an in vivo study of adenovirus-mediated transfer of the human transforming growth factor beta 1 encoding gene" Spine 24(23):2419-25. 
Suh et al. (2002), "Delivery of recombinant human bone morphogenetic protein-2 using a compression-resistant matrix in posterolateral spine fusion in the rabbit and in the non-human primate" Spine 27(4):353-60.

October 17, 2002

Jon Gimbel and Samir Mehta: 
Jackson et al. (2001), "Spontaneous repair of full-thickness defects of articular cartilage in a goat model. A preliminary study. J Bone Joint Surg 83-A(1):53-64. 
O'Driscoll (1998), "The healing and regeneration of articular cartilage" J Bone Joint Surg 80(12):1795-812.

April 24, 2002

Jeff Cartmell and Michele Favata: 
Spindler et al. (2002), "Collagen expression and biomechanical response to human recombinant transforming growth factor beta (rhTGF-beta2) in the healing rabbit MCL" J Orthop Res 20:318-24. 
Fenwick et al. (2001), "Expression of transforming growth factor-beta isoforms and their receptors in chrnoic tendinosis" J Anat 199:231-40.

March 20, 2002

Paul Robinson and Sam Young: Thompson et al. (1996), "A Biomechanical Analysis of Rotator Cuff Deficiency in a Cadaveric Model" Am J Sports Med 24(3):286-92. 
Harryman et al. (1991), "Repairs of the Rotator Cuff: Correlation of Functional Results With Integrity of the Cuff" J Bone Joint Surg 73-A(7):982-9.

February 27, 2002

Wade Johannessen and Heather Lynch: 
Adams et al. (1996), "Stress Distributions Inside Intervertebral Discs: The Effects of Age and Degeneration" J Bone Joint Surg 78(6):965-72. 
Hutton et al. (1999), "The Effect of Hydrostatic Pressure on Intervertebral Disc Metabolism" Spine 24(15):1507-15.

January 23, 2002

Tony Lin and J Sarver: 
Woo et al. (1981), "The Time and History-Dependent Viscoelastic Properties of the Canine Medial Collateral Ligament" J Biomech Eng 103:293-8. 
Provenzano et al. (2001), "Nonlinear Ligament Viscoelasticity" Ann Biomed Eng 29:908-14.

November 8, 2001

Tony Lin and Paul Robinson: 
Caprise et al. (2001), "The Effect of NKISK on tendon in an in vivo model" J Orthop Res 19:858-61. 
Thornton et al. (2001), "Altering ligament water content affects ligament pre-stress and creep behaviour" J Orthop Res 19:845-51.

October 23, 2001

Jon Gimbel and Steph Perry: 
Dejardin et al. (2001), "Tissue-Engineered Rotator Cuff Tendon Using porcine Small Intestine Submucosa" Am J Sports Med 29(2):175-84. 

Badylak et al. (1995), "The use of xenogeneic small intestinal submucosa as a biomaterial for Achille's tendon repair in a dog model" J Biomed Mater Res 29:977-85.

 

 

 

 

 

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February 13, 2012    

Wosczyna MN, Biswas AA, Cogswell CA, Goldhamer DJ. Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification.

January 16, 2012

Hsiao EC, Millard SM, Louie A, Huang Y, Conklin BR, Nissenson RA. Ligand-Mediated Activation of an Engineered Gs G Protein-Coupled Receptor in Osteoblasts Increases Trabecular Bone Formation.

December 12, 2011

Shimono K, Tung WE, Macolino C, Chi AH, Didizian JH, Mundy C, Chandraratna RA, Mishina Y, Enomoto-Iwamoto M, Pacifici M, Iwamoto M. Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-gamma agonists.

November 14, 2011

Li G, Zheng B, Meszaros LB, Vella JB, Usas A, Matsumoto T, Huard J. Identification and characterization of chondrogenic progenitor cells in the fascia of postnatal skeletal muscle.

October 10, 2011

Zaiss MM, Axmann R, Zwerina J, Polzer K, Guckel E, Skapenko A, Schulze-Koops H, Horwood N, Cope A, Schett G. Treg cells suppress osteoclast formation: a new link between the immune system and bone.

September 12, 2011

Liu Y, Wang L, Fatahi R, Kronenberg M, Kalajzic I, Rowe D, Li Y, Maye P. Isolation of murine bone marrow derived mesenchymal stem cells using Twist2 Cre transgenic mice.

February 27, 2006

Reem Kanaan, Steven Lietman, Changlin Ding, David Cooke, Michael Levine. Reduction in Gsa induces osteogenic differentiation in human mesenchymal stem cells. Clinical Orthopaedics and Related Research 434: 231-238, 2005.

January 26, 2006

David Glaser, Toshiyuki Matsuoka, Per E. Ahlberg, Nicoletta Kessaris, Palma Iannarelli, Ulla Dennehy, William D. Richardson, Andrew P. McMahon and Georgy Koentges. Neural crest origins of the neck and shoulder. Nature 436: 347-355, 2005.

December 19, 2005

Jennifer Fiori, Stephen E. Kendall, Chiara Battelli, Sarah Irwin, Jane G. Mitchell, Carlotta A. Glackin, and Joseph M. Verdi. NRAGE mediates p38 activation and neural progenitor apoptosis via the bone morphogenetic protein signaling cascade. Molecular and Cellular Biology 25(17): 7711-7724, 2005.

November 3, 2005

Paul Billings, Didier Montarras, Jennifer Morgan, Charlotte Collins, Frederic Relaix, Stephane Zaffran, Ana Cumano, Terence Partridge, Margaret Buckingham. Direct isolation of satellite cells for skeletal muscle regeneration. Science 309: 2064-2067, 2005.

October 24, 2005

George Feldman, Laurie A. Boyer, et al (2005). Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122: 1-10.

August 11, 2005

Berangere Saucy, A. Afshan Ali, Robert S. Weinstein, Scott A. Stewart, A. Michael Parfitt, Stavros C. Manolagas, and Robert L. Jilka. Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation. Endocrinology 146(3): 1226-1235, 2005.

April 28, 2005

Paul Billings, Trina K. Jeffery, Paul D. Upton, Richard C. Trembath and Nicholas W. Morrell. BMP4 inhibits proliferation and promotes myocyte differentiation of lung fibroblasts via Smad1 and JNK pathways. Am J Physiol Lung Cell Mol Physiol 288:L370-L378, 2005.

February 22, 2005

Reem Kanaan, Jie Liu, Julie G. Nealon and Lee S. Weinstein (2005). Distinct patterns of abnormal GNAS imprinting in familial and sporadic pseudohypoparathyroidism type 1B. Human Molecular Genetics 14 (1): 95-102.

January 25, 2005

George Feldman, Ritsert C. Jansen and Jan-Peter Nap (2004). Regulating gene expression: surprises still in store. Trends Genet 20(5):223-225. Gael Yvert, et al (2003). Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. Nature Genetics 35(1): 57-64.

December 14, 2004

Gisela Melcon, M.D., Research Associate: Jan Hellemans et al (2004). Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis. Nature Genetics 36(11): 1213-1218.

November 16, 2004

Jennifer Fiori, Graduate Student:Hui-Kuan Lin, Stephan Bergmann & Pier Paolo Pandolfi (2004). Cytoplasmic PML function in TGF-Beta signalling. Nature 431:205-211. Christine LeRoy and Jeffrey L. Wrana (2004). An unexpected social servant Nature 431:142.

October 26, 2004

Paul Billings, Ph.D., Research Associate:Lixin Kan, Min Hu, William A. Gomes, and John A. Kessler Transgenic Mice Overexpressing BMP4 Develop a Fibrodysplasia Ossificans Progressiva (FOP)-Like Phenotype. American Journal of Pathology 165: 1107-1115, 2004

July 28, 2004

Reem Kanaan, PhD, Research Associate:Piero Crespo, Teresa G. Cachero, Ningzhi Xu, and J. Silvio Gutkind. Dual Effect of Adrenergic Receptors on Mitogen-activated Protein Kinase. Journal of Biological Chemistry 270: (42) 25259-25265, 1995.

June 23, 2004

George Feldman, D.M.D., Ph.D., Research Associate: Peter Bialek, et al. A Twist Code Determines the Onset of Osteoblast Differentiation. Developmental Cell 6: 423-435, 2004.

May 27, 2004

Brett Gibson, M.D., Orthopaedic Resident:Joanna L. Ford, Derek E. Robinson, Brigitte E. Scammell. (2004) Endochondral ossification in fracture callus during long bone repair: the localisation of 'cavity-lining cells' within the cartilage. Journal of Orthopaedic Research 22, 368-375.

April 28, 2004

XiangYang Jaio, M.D., Research Associate: William F. Pendergraft, Gloria A. Preston, Ruchir R. Shah, Alexander Tropsha, Charles W. Carter, J. Charles Jennette, Ronald J. Falk. Autoimmunity is triggered by cPR-3 (105-201), a protein complementary to human autoantigen proteinase-3. Nature Medicine 10(1):72-79, 2004.

March 24, 2004

Paul Billings, Ph.D., Research Associate:Seto, H., Kamekura, S., Miura, T., Yamamoto, A. Chikuda, H., Ogata, T., Hiraoka, H., Oda, H., Nakamura, K., Kurosawa, H., Chug, U.I., Kawaguchi, H. and Tanaka, S. Distinct roles of Smad pathways and p38 pathways in cartilage-specific gene expression in synovial fibroblasts. Journal of Clinical Investigation 113: 718-726, 2004 Byfield, S.D. and Roberts, A.B. Lateral signaling enhances TGF-b response complexity. Trends in Cell Biology 14: 107-111, 2004

February 18, 2004

Reem Kanaan, Ph.D., Research Associate: Spinella-Jaegle, S. Roman-Roman, C. Faucheu, F.-W. Dunn, S. Kawai, S. Gallea, V. Stiot, A.M. Blanchet, B. Courtois, R. Baron, and G. Rawadi. Opposite effects of bone morphogenetic protein-2 and transforming growth factor-1 on osteoblast differentiation. Bone 29(4):323-330, 2001.

January 28, 2004

Paul Billings, Ph.D., Research Associate:Rajiv D. Machado, Nung Rudarakanchana, Carl Atkinson, Julia A. Flanagan, Rachel Harrison, Nicholas W. Morrell and Richard C. Trembath. Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension. Human Molecular Genetics, Vol. 12(24): 3277-3286, 2003.Marcos Gonzalez-Gaitan and Harald Stenmark. Endocytosis and Signaling: A Relationship under Development. Cell, 115:513-521, November 26, 2003.

December 23, 2003

George Feldman, D.M.D., Ph.D. Research Associate:Frank B. Dean, Seiyu Hosono, Linhua Fang, Xiaohong Wu, A. Fawad Faruqi, Patricia Bray-Ward, Zhenyu Sun, Qiuling Zong, Yuefen Du, Jing Du, Mark Driscoll, Wanmin Song, Stephen F. Kingsmore, Michael Egholm, and Roger S. Lasken. Comprehensive human genome amplification using multiple displacement amplification. PNAS 99(8): 5261-5266, April 16, 2002.

October 29, 2003

Jennifer Fiori, Graduate Student:Shepherd T. and Nachtigal, M. Identification of a Putative Autocrine Bone Morphogenetic Protein Signaling Pathway in Human Ovarian Surface Epithelium and Ovarian Cancer Cells. Endocrinology 2003; 144(8):3306-3314. Fu, Y., O'Connor, L., Shepherd, T., Nachtigal, M. The p38 Inhibitor, PD169316, Inhibits Transforming Growth Factor Beta Induced Smad Signaling in Human Ovarian Cancer Cells. Biochemical and Biophysical Research Communications 2003; 310:391-397.

August 27, 2003

Chuanzhao Li, Ph.D., Research Associate: Haleem J. Issaq, Timothy D. Veenstra, Thomas P. Conrads, and Donna Felschow. The SELDI-TOF MS Approach to Proteomics: Protein Profiling and Biomarker Identification. Biochemical and Biophysical Research Communications 2002; 292: 587-592. Lisa H. Cazares, Bao-Ling Adam, Michael D. Ward, Suhail Nasim, Paul F. Schellhammer, O. John Semmes and George L. Wright, Jr. Normal, Benign, Preneoplastic, and Malignant Prostate Cells Have Distinct Protein Expression Profiles Resolved by Surface Enhanced Laser Desorption/Ionization Mass Spectrometry. Clinical Cancer Research 2002; 8: 2541-2552.

July 30, 2003

XiangYang Jaio, M.D., Research Associate: Warren, S.M., Burnet, L.J., Harland, R.M., Economides, A.N., Longaker, M.T. The BMP antagonist noggin regulates cranial suture fusion. Nature 2003; 422:625-629.

May 28, 2003

George Feldman, D.M.D., Ph.D., Research Associate: Y.Kanzaki, F. Onoue, H. Sakurai, and T. Ide (2003). Telomerase upregulates expression levels of interleukin (IL)-1 alpha, IL-1 beta, IL-6, IL-8 and granulocyte-macrophage colony-stimulating factor in normal human fibroblasts. BBRC 305: 150-154.C. Lindvall, M. Hou, T. Komurasaki, C. Zheng, M. Henriksson, J. Sedivy, M. Bjorkholm, B.T. Teh, M. Nordenskjold, and D. Xu (2003). Molecular Characterization of Human Telomerase Reverse Transcriptase-immortalized Human Fibroblasts by Gene Expression Profiling: Activation of the Epiregulin Gene1,2. Cancer Research 63, 1743-1747.D.Aisner, W. Wright, and J. Shay (2002). Telomerase regulation: not just flipping the switch. Oncogenes and cell proliferation, 80-85.

February 11 , 2003

Jen Fiori, Graduate Student: G. Praveen Raju, Neviana Dimova, Peter S. Klein, and Hui-Chuan Huang (2003). SANE, a Novel LEM Domain Protein, Regulates Bone Morphogenetic Protein Signaling through Interaction with Smad1. Journal of Biological Chemistry 278(1): 428-437.

December 17, 2002

Shelby Blythe, Graduate Student:Shu Takeda, Florent Elefteriou, Regis Levasseur, Xiuyun Liu, Liping Zhao, Keith L. Parker, Dawna Armstrong, Patricia Ducy and Gerard Karsenty (2002). Leptin regulates bone formation via the sympathetic nervous system. Cell 111, 305-317.

November 26, 2002

Bob Pignolo, M.D., Ph.D. Research Fellow:Transdifferentiation Into Osteoblasts: Jeremy Skillington, Lisa Choy and Rik Derynck (2002). Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes. The Journal of Cell Biology 159 (1):135-146.

October 15, 2002

George Feldman, D.M.D., Ph.D. Research Associate: Gerald R. Crabtree and Eric N. Olson (2002). NFAT Signaling: Choreographing the Social Lives of Cells. Cell 109:S67-S79.Ann M. Ranger, Louis C. Gerstenfeld, Jinxi Wang, Tamiyo Kon, Hyunsu Bae, Ellen M. Gravallese, Melvin J. Glimcher, and Laurie H. Glimcher (2000). The Nuclear Factor of Activated T Cells (NFAT) Transcription Factor NFATp (NFATc2) Is a Repressor of Chondrogenesis. J. Exp. Med 191:9-21.Masuhiro Tomita, Martina I. Reinhold, Jeffery D. Molkentin, Michael C. Naski (2002). Calcineurin and NFAT4 Induce Chondrogenesis. JBC Papers in Press. Published on September 17, 2002.

July 30, 2002

Deyu Zhang, Research Associate:X. Han and S. Amar (2002). Identification of Genes Differentially Expressed in Cultured Human Periodontal Ligament Fibroblasts vs. Human Gingival Fibroblasts by DNA Microarray Analysis. J Dent Res 81(6):399-405.

July 2, 2002

Chuanzhao Li, Ph.D., Research Associate:Nakashima K., Zhou X., Kunkel G., Zhang Z., Deng JM., Behringer RR., and de Crombrugghe B (2002). The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 108(1):17-29, 2002 Jan 11.

June 4, 2002

Yangguan Wu, M.D., Research Associate:Kenneth W. Liechty, Tippi C. MacKenzie, Aimen F. Shaaban, Antoneta Radu, AnneMarie B. Moseley, Robert Deans, Daniel R. Marshak and Alan W. Flake (2000). Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nature Medicine 6(11):1282-1286.William M. Rideout III, Konrad Hochedlinger, Michael Kyba, George Q Daley, and Rudolf Jaenisch (2002). Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy. Cell 109: 17-27.

April 23, 2002

Lourdes Serrano de la Pena, Ph.D. Post Doc:Anja Nohe, Sylke Hassel, Marcelo Ehrlich, Florian Neubauer, Walter Sebald, Yoav I. Henis, and Petra Knaus (2002). The Mode of Bone Morphogenetic Protein (BMP) Receptor Oligomerization Determines Different BMP-2 Signaling Pathways. Journal of Biological Chemistry, 277(7): 5330-5338.

March 26, 2002

George Feldman, D.M.D., Ph.D., Research Associate:Trey Ideker, Vesteinn Thorsson, Jeffrey A. Ranish, Rowan Christman, Jeremy Buhler, Jimmy K. Eng, Roger Bumgarner, David R. Goodlett, Ruedi Aebersold, Leroy Hood (2001). Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network. Science, Vol. 292:929-933.

March 5, 2002

Paul Billings, Ph.D., Research Associate:Askew GR, Doetschman T and Lingrel JB (1993). Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy Mol Cell Biol 13, 4115-4124. Stem cells: A primer. National Institutes of Health May 2000.

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