Orthopaedic Research Laboratory Departmental Seminars

McKay Orthopaedic Research Laboratory Seminars

March 21, 2024

Kyriacos Athanasiou, PhD, Distinguished Professor of Biomedical Engineering; the Director of DELTAi (Driving Engineering & Life-science Translational Advances and the Samueli Endowed Chair from the University of California, Irvine, "Translating Cartilage Regeneration Research"

June 27, 2023

Eli Zelzer, PhD, Professor, Weizmann Institute of Science Israel, "From Flat to Form: A 3D Perspective on Bone Growth Plates"

April 18, 2023

McKay DEI Seminar: "Conversation About Diversity: How We Process, Engage, and Support Our Community"
Vincent Walford, Ph.D., Embedded Psychologist at Penn Medicine/BGS
Alaina Spiegel, Psy.D., Staff Psychologist, Coordinator of Prevention Programs

November 30, 2022

L. Scott Levin, MD, FACS, Chair of the Department of Orthopaedic Surgery and Professor of Plastic Surgery in Surgery and the Paul B. Magnuson Professor of Bone and Joint Surgery, "Leadership"

November 4, 2022

Kathryn Song Eng Cheah, PhD, Professor, School of Biomedical Sciences, Hong Kong University, "The Physiological Significance of the Chondrocyte to Osteoblast Lineage Continuum"

May 12, 2022

Amato J. Giaccia, PhD, Director, MRC Oxford Institute for Radiation Oncology University of Oxford, "Regulation of Bone Metastasis by Hypoxia"

December 18, 2020

Scott Levin, MD, FACS, Chair of the Department of Orthopaedic Surgery and Professor of Plastic Surgery in Surgery and the Paul B. Magnuson Professor of Bone and Joint Surgery, University of Pennsylvania,
"The Next Twelve Years - Culture, Leadership, Innovation and Growth"

October 13, 2020

Batsirai Bvunzawabaya, PhD Director of Outreach and Prevention Services, Psychologist
Eva Wilson, MA Psychology Doctoral Intern
Jazmyne Peters, PhD Post Doctoral Psychology Fellow
Eddie Chong, PhD Post Doctoral Psychology Fellow

CAPS (Counseling and Psychological Services) Workshop on Microaggressions and Mental Health
• Review common microaggressions and themes
• Describe the impact of microaggressions on mental health
• Practice skills on how to address microaggressions

July 13, 2020

Malik Muhammad, Associate Director of the LGBT Center
Broadening Your Perspectives Workshop

January 16, 2020

Andrew Carr, DSc, FRCS, FMedSci, University of Oxford, UK, "Using biophysical cues to influence inflammation, fibrosis and repair in human tendon disease"

November 25, 2019

Ernestina Schipani, MD, PhD, University of Michigan, "The Hypoxia-driven pathway and reprogramming of metabolism in skeletal development"

November 14, 2019

Do-Gyoon Kim, PhD, Ohio State University, "Multiscale Characterizations of Dental and Orthopaedic Bone"

July 10, 2019

Rachel Miller, PhD, Rush University, "Investigating Mechanosensitive Ion Channel Signaling in Osteoarthritis"

May 23, 2019

Elazar Zelzer, PhD, Weizmann Institute of Science, "The  importance  of  cross-tissue  regulation  for musculoskeletal  assembly  and  function"

May 21, 2019

Anne-Marie Malfait, MD, PhD, Rush Medical College, "Joint pathology and neuroplasticity in the development of osteoarthritis pain"

April 12, 2019

Jay Jiang, PhD, University of Maryland, "The Role of CCN in Tendon, Cartilage and Bone Development"

March 28, 2019

Wei Hsu, PhD, University of Rochester, "Skeletal stem cells: from development & disease to regenerative medicine"

January 10, 2019

L. Scott Levin, MD, FACS, University of Pennsylvania, "Value and Import of Research in Academic Medicine"

December 17, 2018

Tamara Alliston, PhD, University of California, San Francisco, "The Central Role of Osteocytes in Skeletal and Systemic Homeostasis and Disease"

November 19, 2018

Karl Lewis, PhD, Indiana University School of Medicine, "The development of intravital imaging techniques for the study of osteocyte calcium signaling in vivo"

April 26, 2018

Jesús Delgado-Calle, PhD, Indiana University, "Osteocytes as Targets for the Treatment of Multiple Myeloma"

January 25, 2018

Teresita Bellido, PhD, Indiana University, "Osteocyte-regulated pathways in bone: from biology to pathophysiology"

December 18, 2017

Elise Morgan, PhD, Boston University, "Weak links aren’t always weak: The mechanics of spine fractures"

March 13, 2017

Denitsa Docheva, PhD, University of Regensburg Medical Centre, "Stem Cells: Players in tendon physiology, disease and repair"

June 14, 2016

Lidan You, PhD, University of Toronto, "Bone cell cross talk under mechanical loading"

June 13, 2016

Ryan Tomlinson, PhD, Johns Hopkins University, "The Role of Sensory Nerves in Bone"

May 2, 2016

Kyu-Sang Joeng, PhD, Baylor College of Medicine, "WNT1-related Osteogenesis Imperfecta: Pathogenic mechanism and potential therapeutics"

April 25, 2016

Kurt Hankenson, DVM, PhD, Laboratory for Comparative Orthopedic Research, "Translating basic science discoveries to regenerative therapeutics: Notch signaling regulation of bone formation"

March 14, 2016

Michael Albro, PhD, Imperial College London, "Mechanical Regulation of Growth Factors in Native and Engineered Tissues of the Synovial Joints"

January 21, 2016

Eve Donnelly, PhD, Cornell University, "Multiscale Mechanical and Compositional Characterization of Bone Tissue in Health and Disease"

November 23, 2015

Louis DeFrate, PhD, Duke University "In Vivo Joint Function and Dysfunction: Implications for Early Onset Osteoarthritis"

September 10, 2015

Nat Dyment, PhD, UConn Health "Defining the tendon lineage to improve tissue engineering strategies"

May 20, 2014

Sarah E. Linley, PhD candidate, Rensselaer Polytechnic Institute, "Enhancing Transport into the Intervertebral Disc In Vivo: The Effects of Loading Induced Convection and Alterations to the Vertebral Endplate Vasculature"

February 13, 2014

Shashank Nawathe, PhD candidate, University of California, Berkeley, "Micromechanics of the Human Proximal Femur"

February 6, 2014

Jennifer L. Puetzer, PhD candidate, Cornell University, "Development of Self-Organizing Tissue Engineered Menisci"

January 16, 2014

Karin Grävare Silbernagel PT, ATC, PhD, University of the Sciences, "Exercise as Treatment for Achilles Tendon Injury: A Clinical Research Perspective"

June 24, 2013

Foteini Mourkioti, PhD, Stanford University, "Stem Cells, Short Telomeres and Oxidative Stress in Regeneration: Insights from a New Musculoskeletal Disease Model"

December 20, 2012

John T. Connelly, Ph.D., Blizard Institute, "Insights into the biophysical regulation of epidermal cell fate using engineered micro-environments"

December 10, 2012    

Nadeen O. Chahine, Ph.D., Hofstra North Shore LIJ, "Identifying Mechanisms of Injury and Repair in the Intervertebral Disc"

December 4, 2012

Kimberly Cooper, Ph.D., Harvard Medical School, "Development and Evolution of Form in the Vertebrate Limb"

November 29, 2012

Frank Beier, Ph.D., The University of Western Ontario, "Signaling Pathways in Skeletal Development and Osteoarthritis"

October 24, 2012

Joel D. Boerckel, Ph.D., Cleveland Clinic, "Mechanical and Biological Regulation of Tissue Regeneration"

May 9, 2012

Christian Gerber, Prof. Dr. med., University of Zurich - Uniklinik Balgrist, "The Effect of Tendon Tearing on the Rotator Cuff Muscles"

December 5, 2011

Jenna Galloway, PhD, Harvard Medical School, "Regulation of Progenitor Cell Specification and Patterning in the Musculoskeletal System"

October 21, 2011

Stavros Thomopoulos, PhD, Washington University, "Structure, Biomechanics, and Mechanobiology in the Attachment of Tendon to Bone"

October 20, 2011

James L. Cook, PhD, University of Missouri, "Translational Modeling of Joint Disease"

May 26, 2011

Leesa Galatz, MD, Washington University School of Medicine, "Rotator Cuff Muscle Degeneration

April 25, 2011

Jean B. Regard, PhD, National Institutes of Health, "G Protein Signaling in Skeletal Development and Disease"

October 25, 2010

Ryan M. Porter, PhD, Harvard Medical School, "Proinflammatory Challenge to Chondrogenesis in situ"

July 13, 2010

Xiaowei Sherry Liu, PhD, Columbia University Medical Center, "Clinical Imaging and the Mechanical Modeling of Bone"

June 3, 2010

Evan L. Flatow, MD, The Mount Sinai School of Medicine, "Understanding Tendon Fatigue Damage"

June 1, 2010

Michael L. Sohaskey, PhD, University of California, "Novel Molecular Pathways in Skeletal Development, Homeostasis and Repair"

May 6, 2010

Frank Beier, PhD, University of Western Ontario, "TGFa Signaling in Cartilage Development and Osteoarthritis"

April 29, 2010

Joseph M. Wallace, PhD, University of Michigan, "Quantitative In Situ Ultrastructural Analysis of Type I Collagen-Based Tissues in Health and Disease"

April 8, 2010

Mark Buckley, Cornell University, "Mapping the Functional Properties of Articular Cartilage under Shear Loading"

September 9, 2009

Gil Navon, PhD, Tel Aviv University, "New MRI Techniques for the Study of Connective Tissues"

July 14, 2009

Johnna Temenoff, PhD, Georgia Institute of Technology, "Biomaterial-Based Approaches to Engineering the Ligament-Bone Interface"

June 29, 2009

Valerie Siclari, PhD, University of Virginia, "The Role of Adrenomedullin in Breast Cancer Bone Metastasis"

May 7, 2009

Martin I. Boyer, MD, Washington University, "Flexor Tendon Biology and Biomechanics"

April 30, 2009

Christopher Harner, MD, University of Pittsburgh, "New Developments in the Sports Medicine Biomechanics Lab at the University of Pittsburgh"

December 11, 2008

Jon J.P. Warner, MD, Massachusetts General Hospital and Brigham and Women's Hospitals and Harvard Medical School, "In Vivo Shoulder Kinematics: What Lies Beneath"

October 28, 2008

Daniel Cortes, West Virginia University, "Guided Waves and Their Trends"

October 21, 2008

Arturo Valentin, Texas A & M University, "Complementary Vasoactivity and Matrix Remodeling: Theoretical Foundations and Predicted Trends"

September 24, 2008

Bridget Deasy, Ph.D., University of Pittsburgh School of Medicine, "Sex-differences in Stem Cells and Muscle Repair"

July 17, 2008

Mark Randolph, M.A.S., Harvard Medical School, Massachusetts General Hospital, "Engineered Cartilage to Integrate and Repair Meniscal Tears"

June 16, 2008

Kurt Spindler, Ph.D., Vanderbilt University, "Translational Animal Models for Clinical Outcomes"

April 16, 2008

Ling Qin, Ph.D., Robert Wood Johnson Medical School, "EGF Receptor Signaling in Bone Metabolism and Cancer Bone Metastasis"

February 25, 2008

Kingston Mak, Ph.D., National Human Genome Research Institute/NIH, "Roles of Hedgehog Signaling in Postnatal Skeletal System"

February 14, 2008

David Komatsu, Ph.D., Indiana University/Eli Lilly, "Impairing and Improving Bone Regeneration: Genetic, Mechanical and Pharmacological Approaches"

January 10, 2008

Regis O'Keefe, M.D., Ph.D., University of Rochester Medical Center, "The Pathogenesis of Osteoarthritis: Molecular Targets for Potential Therapeutics"

May 24, 2007

Richard Gelberman, M.D., Washington University, "Advances in Tendon Repair"

February 8, 2007

Kurt Spindler, M.D., Vanderbilt University, "Intraarticular Healing of the ACL"

March 7, 2006

Rocky Tuan, Ph.D., NIAMS/NIH, "Developmental Paradigms for Cell-Based Tissue Engineering"

February 21, 2006

X. Edward Guo, Ph.D., Columbia University, "Mechanobiology of Bone"

December 13, 2005

Jeffrey Lotz, Ph.D., University of California, San Francisco, "Biomechanics of Back Pain"

November 29, 2005

Bob Pignolo, M.D., Ph.D., "Lab poster session"

November 8, 2005

David Birk, Ph.D., Thomas Jefferson University, "Development of Tendon Extracellular Matrix Structure and Function: Regulation by Collagen and Proteoglycan Interactions"

September 15, 2005

Steven Arnoczky, Ph.D., "Mechanotransduction in Tendon Cells: Implications for Rehabilitation and Overuse Injuries"

September 6, 2005

Rob Mauck, Ph.D., "Lab poster session"

July 26, 2005

Richard Lieber, Ph.D., University of California, San Diego, "Intraoperative Laser Diffraction Studies of Human Muscle in Hand Surgery

May 17, 2005

Jeff Weiss, Ph.D., University of Utah, "Angiogenesis and the Extracellular Matrix"

April 19, 2005

Kai-Nan An, Ph.D., Mayo Clinic, "Tendon Biomechanics and Clinical Applications"

March 8, 2005

Louis Soslowsky, Ph.D., "Lab poster session"

February 15, 2005

Matthew Silva, Ph.D., Washington University, "The SAMP6 Mouse Model of Senile Osteoporosis: Biomechanics and Mechanobiology"

November 30, 2004

Carl Brighton, M.D., Ph.D. and Chris Clark, Ph.D., "Lab poster session"

October 21, 2004

Don Chaffin, Ph.D., University of Michigan, "Human Motions at Work and Their Biomechanical Implications"

October 12, 2004

Katrin McGowen, Ph.D., University of Pennsylvania, "Obstacles to Good Time Management"

September 21, 2004

Dawn Elliott, Ph.D., "Lab poster session"

June 24, 2004

Timothy Baradet, Ph.D. "Orthopaedic Histology at The McKay Laboratory"

May 3, 2004

Jay Humphery, Ph.D., Texas A&M University, "Biomechanics of Arterila Growth and Remodeling"

April 20, 2004

Louis Soslowsky, Ph.D., "Lab poster session"

February 17, 2004

Fred Kaplan, M.D., Eileen Shore, Ph.D., "Lab poster session"

January 19, 2004

Rob Mauck, Ph.D., Columbia University, "Functional Tissue Engineering of Articular Cartilage: Challenges and Opportunities"

December 16, 2003

James Goh, Ph.D., National University of Singapore, "Tissue Engineering Approaches to Tendon and Ligament Repair and Regeneration"

September 16, 2003

Richard Brand M.D., Editor, Clinical Orthopaedics and Related Research, "How to write a Research Paper"

May 6, 2003

Steve Nicoll, Ph.D., "Regulating Cellular Phenotype for Connective Tissue Engineering Applications"

April 10, 2003

Rob Mauck, Ph.D., Columbia University, "Functional Approaches to Articular Cartilage Tissue Engineering and Repair"

February 20, 2003

Jason A. Burdick, Ph.D., Massachusetts Institute of Technology, "Utilizing Photopolymerization in the Field of Tissue Engineering: Specific Applications in Bone Regeneration"

January 7, 2003

Donna Dean, Ph.D., Deputy Director, NIBIB, NIH, "Exciting New Research Funding Opportunities in Bioengineering and Imaging"

December 19, 2002

Scott Boden, M.D., Emory University, "Gene Therapy for Spine Disorders"

December 9, 2002

Joe Iannotti, M.D., Ph.D., Cleveland Clinic Foundation, "Glenohumeral Kinematics and Prosthetic Design"

October 7, 2002

Lisa Belincampi, Ph.D, Orthovita Inc., "Biomedical Engineering and Orthopaedics in Industry"

April 30, 2002

Vivian Cheung, M.D., Assistant Professor Children's Hospital of Philadelphia, "Expression Phenotyping Using cDNA Microarrays"

April 11, 2002

Dr. Barrack, M.D., Faculty Tulane University, "Implant Bearing Surfaces"

March 21, 2002

Andy Putnam Ph.D., University of Michigan, "Materials for Tissue Engineering"

February 5, 2002

Prasad Shastri, Ph.D., CHOP, "Tissue Engineering Fundamentals for Connective Tissue Repair"

November 11, 2001

John Emery, Ph.D., GlaxoSmithKline, "Characterization of BMPs, receptors, and signalling intermediates during human mesenchymal stem cell differentiation"

October 23, 2001

Haidi Zhang, M.D., Ph.D., Research Associate, Rheumatology, "Development of molecular synovectomy using 'gene scalpels' for the treatment of rheumatoid arthritis and other arthropathies"

September 25, 2001

David L. Diefenderfer, V.M.D., Ph.D., University of Pennsylvania, "BMP-Induced Osteogenesis in Human Marrow Stromal Cells"

McKay Young Investigator Seminars

This seminar series was designed to highlight the research and achievements of up and coming young scientists in the McKay Orthopaedic Research Lab. The goal of this seminar series is to provide a forum for senior graduate students, post docs and research associates who are poised to embark on the next stage of their careers to present their work to the department, and to stimulate discussion and collaboration between individual McKay labs.

April 2, 2024

Elena Sabini, MD Research Associate, Schipani Lab “ Loss of TFAM impairs cortical bone accrual, and HIF1 activation corrects the defect”

April 2, 2024

Erin Berlew, PhD Research Associate, Boerckel Lab “Optogenetics for mechanobiology using BcLOV4”

April 2, 2024

Jonathan Marcelin, B.E. Graduate Student, Dyment Lab “Localized Delivery of a Hedgehog Agonist to Enhance Tendon-to-Bone Integration”

February 13, 2024

Loreilys Mejías Rivera PhD Student, Shore Lab “Periosteal Pdgfra-lineage Cells Contribute To Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva”

February 13, 2024

Elisabeth Lemmon VMD-PhD student, Mauck Lab “Interleukin Receptor Therapeutics Attenuate Synovial Inflammation in Canines following Cruciate Ligament Injury. ”

December 5, 2023

Georgios Kotsaris, Ph.D. Postdoctoral Researcher, Mourkioti Lab “The NF-κB pathway regulates muscle stem cells’ regenerative potential in injury”

December 5, 2023

Katy Strand Graduate Student, Hast Lab “Exploring the Efficacy of Additively Manufactured PLGA Implants for Fracture Repair at Early Time Points”

December 5, 2023

Zizhao (Molly) Li, M.S. Graduate Student, Heo Lab “Tunable Extracellular Matrix-Based Multiphasic Scaffold Systems for Rotator Cuff Repair”

October 10, 2023
Xiaoyu Xu, Ph.D. Postdoctoral Fellow, Liu Lab “Conditional Deletion of PTH/PTHrP Receptor 1 in Osteocytes Abolishes Lactation-induced Alterations in Canalicular Pericellular Space and Increases Bone Microstructure Deterioration”
June 20, 2023

Giulia Lanzolla, M.D. Postdoctoral Researcher, Schipani Lab “Pharmacologic inhibition of HIF2 prevents trabecular bone loss in ovariectomized mice”

June 20, 2023

Rashad Madi, M.D. Postdoctoral Researcher, Dyment Lab “Localized Release of a Hedgehog Signaling Agonist for Improving Tendon-to-Bone Integration”

June 20, 2023

Eon Zhang Graduate Student, Heo Lab “Epigenetic Regulation of Meniscus Cell Migration and its Zonal Dependency in Response to Inflammatory Conditions”

April 11, 2023

Michael DiStefano, B.S. Graduate Student, Soslowsky Lab “Mouse Supraspinatus Tendon Mechanical and Structural Properties Are Dependent on Region and Age”

April 11, 2023

Michael Duffy, Ph.D. Postdoctoral Fellow, Qin Lab “Transcriptomic profiling of human bone marrow and the characterization of mesenchymal progenitor cells”

April 11, 2023

Maggie Wagner, B.S Graduate Student, Baxter Lab “Ti3C2 MXene-based high-density surface electromyography arrays for sensing and recording plantar flexor muscle activity”

February 7, 2023

Yasaman Moharrer Ph.D. Student, Boerckel Lab “Yap and Taz Mediate Mechanoregulation Of Embryonic Bone Formation and Bone Growth”

February 7, 2023

Sereen Assi Ph.D. Student, Mauck Lab “Superficial Meniscus Cells are Highly Proliferative and Migratory and Generate Functional Tissue”

February 7, 2023

Brendan Stoeckl Ph.D. Student, Mauck Lab “Regional Multi-Scale Analysis of Osteoarthritis Progression Across the Human Trapezium”

December 6, 2022

Ke Song, Ph.D. Postdoctoral fellow, Baxter Lab “Patellofemoral joint loading progression across 35 rehabilitation exercises and activities of daily living”

December 6, 2022

Jiawei Lu, Ph.D. Visiting student, Qin Lab “Tracking PRG4 positive cells in the healing process after long bone fracture and interveterbral disc injury. ”

December 6, 2022

Joe Ulsh, Ph.D. Master student, Hast Lab “Functionally Graded Lattices in Additively Manufactured Rib Implants Do Not Change Failure Mechanisms”

October 4, 2022

Ji-Hyung Lee, Ph.D. Postdoctoral fellow, Mourkioti Lab “An essential telomere protein for muscle stem cell function and regeneration during homeostasis, disease, and aging”

October 4, 2022

Karthikeyan Rajagopal, Ph.D. Postdoctoral fellow, Smith/Malhotra Lab “Physiological assessment of the nucleus pulposus microenvironment in a large animal model of disc degeneration: preliminary findings”

June 7, 2022

Jaime Santillan, Ph.D. Postdoctoral fellow, Soslowsky Lab “Assessment of Mouse Cervix under Dynamic Loading at Different Gestational Stages”

June 7, 2022

Se-Hwan Lee, Ph.D. Postdoctoral fellow, Heo Lab “Development of Age-dependent Extracellular Matrix-Based Hydrogel Systems for Meniscus Repair”

June 7, 2022

Annemarie Lang, Ph.D. Postdoctoral fellow, Boerckel Lab “Heterogeneity of cellular hypoxia in murine bone marrow”

April 19, 2022

Tala Azar, B.E. Graduate Student, Liu Lab “Dynamics of New Bone Formation in a Cyclic Treatment Regimen of Parathyroid Hormone-related Peptide (PTHrP)”

April 19, 2022

Elena Sabini, M.D. Postdoctoral fellow, Schipani Lab “Role of TFAM in Development and Energy Metabolism in Chondrocytes of the Fetal Growth Plate”

April 19, 2022

Mary Kate Evans, B.S. Graduate Student, Dyment Lab “Non-muscle Myosins are Critical Regulators of Skeletal and Connective Tissue Formation”

February 22, 2022

Hannah Zlotnick, B.S. Graduate Student, Mauck Lab “Reimagining conferences as platforms to provide early research exposure and networking to diverse undergraduates”

February 22, 2022

Christelle Darrieutort-Laffite, Ph.D. Postdoctoral fellow, Soslowsky Lab “The injury response of aged tendons after induced knockdown of decorin and biglycan during the proliferative and remodeling phases of healing”

February 22, 2022

Yeonju Lee, Ph.D. Postdoctoral fellow, Joeng Lab “The regulation of tenocyte differentiation and morphological maturation by mTORC1 signaling”

December 7, 2021

Madhura Nijsure, B.S. Graduate Student, Boerckel Lab “YAP mediated transcriptional regulation of periosteal cell proliferation”

December 7, 2021

Richa Gupta, B.S. Research Specialist, Hast Lab “Double Cortical Button and Docking Techniques for Ulnar Collateral Ligament Reconstruction Result in Similar Biomechanics: A Cadaveric Evaluation”

December 7, 2021

Ryan Leiphart, B.S. Graduate Student, Soslowsky Lab “The Pericellular Matrix is Implicated in Regional Development of "WrapAround" Tendons”

October 19, 2021

Sienna Pyle, B.S. Graduate Student, Mourkioti Lab "The role of telomeric repeat binding factor 2 (TRF2) in cardiac health and development”

October 19, 2021

Mohd Khan, Ph.D. Postdoctoral Research Fellow, Schipani Lab “Role of mitochondrial transcription factor A (TFAM) and hypoxia inducible factor1alpha (HIF-1a) in bone mass accrual”

October 19, 2021

Ellen (Yujia) Zhang B.S. Graduate Student, Heo Lab "Epigenetic strategies for preserving chondrocyte phenotype during in vitro expansion"

September 21, 2021

Todd Hullfish, B.S. Research Specialist, Baxter Lab “Defining Mechanical Loading as a Therapeutic Tool to Rehabilitate Achilles Tendon Injuries”

September 21, 2021

Matthew Fainor, B.S. Research Engineer, Gullbrand Lab “Optimizing a total tissue engineered disc for improved osseointegration”

September 21, 2021

Chenghao Zhang, Ph.D. Postdoctoral Researcher, Smith Lab “Single-cell transcriptomics of the intervertebral disc nucleus pulposus”

August 24, 2021

Ryan Locke, Ph.D. Postdoctoral Research Fellow, Mauck Lab "Mechano-instructive material inclusions to direct meniscus repair”

August 24, 2021

Vitali Lounev, Ph.D. Research Specialist, Shore/Kaplan Lab “MMP-9 deficiency confers resilience in Fibrodysplasia Ossificans Progressiva”

August 24, 2021

Yilu Zhou, Ph.D. Postdoctoral Research Fellow, Liu Lab “Structural and cellular responses of supraspinatus tendon enthesis and subchondral bone to reproductive cycles and estrogen deficiency”

May 18, 2021

Jaclyn Carlson, B.S. Graduate Student, Soslowsky Lab "Collagen V Haploinsufficiency Results in Delayed Healing and Altered Wound Matrix Post-Injury in Murine Tendons”

May 18, 2021

Tao Gui, B.S. Visiting Student, Qin Lab “Novel ROS-scavenging nanoparticles attenuate mouse osteoarthritis”

May 18, 2021

Tonia Tsinman, B.S. Graduate Student, Mauck/Dyment Lab “Impact of non-muscle myosins on meniscus development”

April 20, 2021

Ryan Daniels, B.S. Graduate Student, Mauck Lab “Cytoskeletal regulation of chondrogenic homeostasis”

April 20, 2021

Tim Kamalitdinov, B.S. Graduate Student, Dyment Lab “Leveraging hedgehog signaling to improve tendon-to-bone repair”

April 20, 2021

Na Rae Park, Ph.D. Postdoctoral research fellow, Joeng Lab "Stat3 mediates the function of mTORC1 in fibrovascular scar formation during postnatal tendon development”


December 1st, 2020

Mohd Parvez Khan, Ph.D. Postdoctoral research fellow, Schipani Lab “Role of Energy Metabolism in Bone Mass Accrual”

December 1st, 2020

Elisia D. Tichy, Ph.D. Instructor, Mourkioti Lab “Poor muscle regeneration and aberrant muscle stem cell function in fibrodysplasia ossificans progressiva”

December 1st, 2020

Jerahme Martinez, Ph.D. Postdoctoral research fellow, Dodge and Scanzello Lab "Discovery of novel post-traumatic osteoarthritis therapeutic compounds using a high throughput mechanical injury platform”

October 6th, 2020

Nuoying Ma, B.S. Graduate Student, Mourkioti Lab “Novel specialized properties of adult muscle stem cells”

October 6th, 2020

Joe Collins, B.S. Graduate Student, Boerckel Lab “A single cell transcriptome analysis of YAP and TAZ in embryonic skeletal development”

October 6th, 2020

Yeonju Lee, Ph.D. Postdoctoral Fellow, Joeng Lab "Scaffold-free 3D tendon cell culture using mouse tendon cells”

August 25th, 2020

Joseph Newton, B.S. Graduate Student, Soslowsky Lab “LabArchives and You: Maximizing the capabilities of our online lab notebooks.”

August 25th, 2020

Zhirui Jiang, Ph.D. Postdoctoral Fellow, Smith Lab “Pathogenesis of delayed endochondral ossification in Mucopolysaccharidosis”

August 25th, 2020

Lutian Yao, M.D. Visiting Scholar, Qin Lab "Gli1 defines a subset of fibro-adipogenic progenitors that promotes skeletal muscle regeneration with less fat accumulation”

June 30, 2020

Ashley Fung, B.S. Graduate Student, Soslowsky Lab “Determining the Roles of Decorin and Biglycan in Tendon Healing”

June 30, 2020

Will Towler, Ph.D. Postdoctoral Fellow, Shore Lab “Regulation of Skeletal and Joint Development by ACVR1”

June 30, 2020

Rebecca Chung, Ph.D. Postdoctoral Fellow, Liu Lab "Delineating the Effects of Pregnancy and Lactation on Maternal Responses to Future Estrogen Deficiency”

May 5, 2020

Wei Yu, MD, Visiting Scholar, Qin Lab "Marrow adipogenic lineage precursors (MALPs) controls bone resorption"

May 5, 2020

John Drazan Ph.D., Postdoctoral Fellow, Baxter Lab "The validation of a novel dynamometer to assess joint level function outside of biomechanics laboratories"

May 5, 2020

Hannah Zlotnick B.S., Ph.D. Student, Mauck Lab "Non-invasive cell and biofactor patterning for improved orthopaedic tissue regeneration"

April 21, 2020

Catherine Bautista Sc.M., Ph.D. Student, Dyment Lab "F4/80 tendon resident macrophages and potential cross-talk with tendon fibroblasts during growth"

April 21, 2020

Brittany Taylor Ph.D., Postdoctoral Fellow, Soslowsky Lab "Localized delivery of Ibuprofen for supraspinatus tendon repair in a rat model"

April 21, 2020

Sonia Bansal B.S., Ph.D. Student, Mauck Lab "Multi-scale changes in meniscus and cartilage in a large animal model of meniscal unloading"

December 3, 2019

Wei-Ju Tseng MS, PhD Student, Liu Lab "Differences in Material Properties of Trabecular Bone Tissue from Modeling- and Remodeling-Based Bone Formation in Rats"

December 3, 2019

Thomas Leahy BS, PhD Student, Soslowsky Lab "The Effect of Age on Achilles Tendon Healing"

December 3, 2019

Na-Rae Park PhD, Postdoctoral Fellow, Joeng Lab "Rcn3 Is Involved In Postnatal Tendon Maturation By Regulating Collagen Fibrillogenesis"

October 8, 2019

Chenghao Zhang PhD, Postdoctoral Fellow, Smith/Malhotra Lab "Stem cell-based intervertebral disc regeneration: progress and challenges in a preclinical large animal model"

October 8, 2019

Ryan Leiphart BS, PhD Student, Soslowsky Lab "Collagen V deficiency during healing mitigates the quasi-static mechanical deficits of injured tendons"

October 8, 2019

Elisia Tichy PhD, Postdoctoral Fellow, Mourkioti Lab "Telomere length regulation of muscle stem cells in chronic injuries"

August 13, 2019

Timur Kamalitdinov, PhD Student, Dyment Lab "Alpha smooth muscle actin-expressing progenitors produce zonal insertion sites in tendon-to-bone repair"

August 13, 2019

Wenzheng Wang MD, Postdoctoral Researcher, Liu Lab "Dynamics of Modeling- and Remodeling-Based Bone Formation in response to intermittent parathyroid hormone"

August 13, 2019

Niambi Brewer, PhD Student, Shore Lab "Gnas inactivation alters adipose tissue properties during progression to heterotopic ossification”

June 18, 2019

Yulong Wei MD, Visiting Graduate Student, Qin Lab "The Regulatory Role of EGFR Signaling in Adult Cartilage Homeostasis and Osteoarthritis"

June 18, 2019

Jay Patel PhD, Postdoctoral Fellow, Mauck Lab ""Biomaterial-Mediated Reprogramming of Cartilage Defects to Localize and Direct Stem Cell Therapies"

April 23, 2019

Tonia Tsinman BS, PhD Student, Mauck/Dyment Labs "Temporal evolution of cell phenotype and biophysical cues in the developing murine meniscus microenvironment"

April 23, 2019

Ana Paula Peredo BS, PhD Student, Mauck/Dodge Labs "Mechanically-Activated Microcapsules for On-Demand Drug Delivery"

April 23, 2019

Joseph Collins BS, PhD Student, Boerckel Lab "YAP and TAZ regulate the formation of the primary ossification center in embryonic limbs"

February 26, 2019

Robyn Allen BA, VMD/PhD Student, Mullins/Shore Labs "BMP-Smad1/5 signaling interactions in a zebrafish model of FOP"

February 26, 2019

Chris Kegelman BS, PhD Student, Boerckel Lab "YAP and TAZ mediate osteocyte perilacunar/canalicular remodeling"

February 26, 2019

Leilei Zhong PhD, Postdoctoral Fellow, Qin Lab "Deciphering the in vivo heterogeneity of mouse bone marrow mesenchymal progenitors at single cell resolution"

December 4, 2018

Cheng Zhou PhD, Postdoctoral Fellow, Scanzello/Dodge Labs "Elucidating the role of inflammatory cells in osteoarthritis"

December 4, 2018

Danielle Rux PhD, Postdoctoral Fellow, Pacifici Lab, "Understanding Roles for the Primary Cilium During
Postnatal Articular Cartilage Morphogenesis"

October 9, 2018

Alexandra Stanley, PhD Student Mourkioti/Shore Labs, "Aberrant muscle tissue repair by mutant ACVR1/ALK2 FOP progenitor cells – implications for heterotopic ossification"

October 9, 2018

Edward Bonnevie PhD, Postdoctoral Fellow Mauck Lab, "Disruption of boundary constraints activates aberrant mechano-sensing in injured intervertebral discs"

August 14, 2018

Hongbo Zhao, Visiting PhD Student, Liu Lab, "Cyclic and Alternating Parathyroid Hormone (PTH) and Alendronate Treatment Regimens Further Improve Bone Microarchitecture and Strength Beyond Daily and Cyclic PTH Regimens"

August 14, 2018

Catherine Bautista, Graduate Student, Dyment Lab, "Identifying a Novel Subset of Tendon Cells"

June 5, 2018

Will Towler, Graduate Student, Shore Lab, "Regulation of phalangeal joint development by ACVR1 in fibrodysplasia ossificans progressiva"

June 5, 2018

Su Chin Heo, Research Associate, Mauck Lab, "Nuclear Softening Expedites Interstitial Cell Migration in Dense Connective Tissues"

April 10, 2018

Zak Beach, Graduate Student, Soslowsky Lab, "The Surprising Roles of Decorin and Biglycan during Tendon Homeostasis"

April 10, 2018

Luqiang Wang, Graduate Student, Qin Lab, "Prior focal radiation causes atrophic nonunion fracture in mice"

February 27, 2018

Devon Mason, Graduate Student, Boerckel Lab, "Persistent cell motility requires transcriptional feedback of cytoskeletal-focal adhesion equilibrium by YAP/TAZ"

February 27, 2018

Justin Bendigo, Graduate Student, Smith Lab, "Preconditioning of mesenchymal stem cells to enhance survival and extracellular matrix production in the intervertebral disc"

October 10, 2017

Yihan Li, Graduate Student, Liu Lab, "Effects of Reproduction and Lactation on Maternal Bone Mechano-Sensitivity"

October 10, 2017

Maryam Sharifi-Sanjani, Postdoctoral Fellow, Mourkioti Lab, "Telomere Dynamics in Cardiac Muscle"

August 15, 2017

Salin Chakkalakal, Senior Research Investigator, Shore Lab, "Development and application of novel FOP mouse models for investigating heterotopic ossification and drug development"

August 15, 2017

Cheng Zhou, Postdoctoral Fellow, Dodge Lab, "Enhanced phagocytic capacity endows chondrogenic progenitor cells with a novel scavenger function within injured cartilage"

June 6, 2017

Xiaoyuan Ma, Postdoctoral Fellow, Qin Lab, "Subchondral bone plate sclerosis during late osteoarthritis is mediated by loading-induced decrease in Sclerostin amount"

June 6, 2017

Robert Mauck, Mary Black Ralston Professor for Education and Research in Orthopaedic Surgery, "Mechanistic insight into renovations and relocations: from single cells to systems"

April 11, 2017

Sarah Gullbrand, Postdoctoral Fellow, Smith and Mauck Labs, "Stem cell and hydrogel-based therapeutics for intervertebral disc regeneration"

April 11, 2017

Bhavana Mohanraj, Graduate Student, Mauck and Dodge Labs, "High Throughput and Mechano-Active Platforms to Promote Cartilage Regeneration and Repair"

February 14, 2017

Julianne Heugel, Senior Researcher, Soslowsky Lab, "Pre-Clinical Rotator Cuff Study: Effects of PEMF on Rotator Cuff Repair in a Rodent Model"

February 14, 2017

Haitao Wang, Senior Researcher Investigator, Kaplan/Shore Lab, "Cellular Hypoxia Promotes Heterotopic Ossification by Amplifying BMP Signaling Pathway"

December 6, 2016

Brian Cosgrove, Graduate Student, Mauck Lab, "N-Cadherin adhesive interactions modulate ECM mechanosensing and fate commitment of mesenchymal stem cells"

October 11, 2016

Cori Riggin, Graduate Student, Soslowsky Lab, "Augmentation of Vascular Response in the Rat Achilles Tendon after Injury"

October 11, 2016

Chantel de Bakker, Graduate Student, Liu Lab, "Structural Adaptations of the Maternal Skeleton in Response to Reproduction and Lactation"

August 16, 2016

Wei Tong, Graduate Student, Qin Lab, "Dynamic vessel and bone formation: a coupled journey"

August 16, 2016

Claire McLeod, Graduate Student, Mauck Lab, "Differentiating Stem Cells Exhibit Molecular and Microenvironmental Heterogeneity"

May 10, 2016

Elisia Tichy, Postdoctoral Fellow, Mourkioti Lab, "Stem cell regulation in chronic muscle injuries"

April 12, 2016

Girish Ramaswamy, Postdoctoral Fellow, Shore Lab, "Gs-alpha Impacts Bone Quality by Regulating Osteoclast Activity During Bone Remodeling"

April 12, 2016

Sun Peck, Postdoctoral Fellow, Smith Lab, "Elucidating the Molecular Mechanisms Behind Failed Bone Formation in Mucopolysaccharidosis VII"

February 2, 2016

Ben Freedman, Graduate Student, Soslowsky Lab, "Surgical treatment and return to activity timing affects Achilles tendon healing in rodents"

February 2, 2016

Michael Convente, Graduate Student, Shore Lab, "The Immunologic Contribution to Heterotopic Ossification Disorders - Insights from FOP"

Penn Center for Musculoskeletal Disorders Seminars

View Seminars »

Orthopaedic Research Club (ORC) Seminars

ORC is a platform for promoting cooperative interaction among investigators who engage in musculoskeletal research at the University of Pennsylvania and neighboring institutes.

June 26, 2024

Reyad Elbarbary, PhD, Associate Professor of Orthopaedics and Rehabilitation, Biochemistry and Molecular Biology, Penn State University, "The potential therapeutic use of cannabinoids in fracture healing"

May 22, 2024

Sebastian Vega, PhD, Assistant Professor of Biomedical Engineering and Orthopaedic Surgery, Rowan University, "Injectable Hydrogels for Biomedical Applications"

April 24, 2024

Brianne Connizzo, PhD, Assistant Professor of Biomedical Engineering and Mechanical Engineering, Boston University, "Bridging the Gap: Understanding Local Tissue Crosstalk in the Rotator Cuff"

March 27, 2024

John Collins, PhD, Assistant Professor of Orthopaedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, "Sirtuin 6 (SIRT6) as a potential therapeutic for osteoarthritis"

February 24, 2024

Lesley Chow, PhD, Associate Professor of Materials Science and Engineering & Bioengineering, Lehigh University, "Spatially controlling biomaterial properties to direct osteochondral tissue formation"

January 24, 2024

Jason (Joohyun) Lim, PhD, Assistant Professor of Biological Sciences, University of Delaware, "Ectopic ossification of the temporomandibular joint (TMJ) in a murine model of Osteogenesis Imperfecta"

October 25, 2023

Koen Van De Wetering, DVM, PhD, Assistant Professor of Orthopaedic Surgery, Thomas Jefferson University, "Endogenous small molecule mineralization regulators: differential effects on bone and soft connective tissues?"

September 27, 2023

Kyra Smith, PhD Student, Department of Bioengineering, University of Pennsylvania, and Department of Surgery, Children's Hospital of Philadelphia, "In vivo Validation of a Continuous Gradient Porous Scaffold for Osteochondral Defect Repair in a Rabbit Model"

September 27, 2023

Gongsheng Yuan, Postdoc Fellow, Department of Basic and Translational Sciences, Penn Dental Medicine, "The Role of Regulator of G Protein Signaling 12 (RGS12) in Inflammatory Arthritis"

July 26, 2023

Casey Humbyrd, MD, MBE, Associate Professor of Orthopaedic Surgery, University of Pennsylvania, "Current translational research and ethics work in foot and ankle"

June 28, 2023

Kyle Vining, DDS, PhD, Assistant Professor of Preventive and Restorative Sciences, Penn Dental Medicine, and Materials Science and Engineering, Penn Engineering, University of Pennsylvania, "Mechanical regulation of monocyte fate in fibrotic niches"

May 24, 2023

Fadia Kamal, PharmD, Msc, PhD, Assistant Professor of Orthopedics and Rehabilitation and Pharmacology, Penn State University, College of Medicine, "Regulating GPCR signaling in cartilage development and disease"

April 26, 2023

Bin Wang, PhD, Associate Professor of Medicine, Center for Translational Medicine, Thomas Jefferson University Medical College, "PTH and PTHrP analog: actions on bone biomarkers"

March 22, 2023

Pallavi Bhattaram, PhD, Assistant Professor of Orthopaedics, Emory University School of Medicine, "Synovial fibroblasts: their roles in joint health and disease"

February 22, 2023

Ambika Bajpayee, PhD, Assistant Professor of Bioengineering, Northeastern University, "Bioelectricity for Cartilage Drug delivery and Imaging"

January 25, 2023

Colleen Wu, PhD, Assistant Professor of Orthopaedic Surgery, Pharmacology and Cancer Biology, and Cell Biology, Duke University School of Medicine, "Novel Strategies to Prevent Radiation Induced Bone Loss"

December 7, 2022

Jennifer Jonason, PhD, Associate Professor of Orthopaedics and Rehabilitation, University of Rochester Medical Center, "The impact of aging on joint homeostasis: inflammation and cell death as mediators of cartilage degeneration"

October 26, 2022

Hang Lin, PhD, Assistant Professor of Orthopaedic Surgery & Bioengineering, University of Pittsburgh, "Emerging Applications of the Miniature Joint System in Studying Osteoarthritis and Developing Treatments"

September 28, 2022

Xiaobin Huang, PhD, Postdoctoral Fellow, Department of Oral and Maxillofacial Surgery, School of Dental Medicine, University of Pennsylvania, "Mandibular condyle contains a unique chondrocyte progenitor population to maintain mandibular bone homeostasis"

September 28, 2022

Minwook Kim, PhD, Postdoctoral Fellow, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, "Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs"

August 17, 2022

Mona Al Mukaddam, MD, Associate Professor of Medicine, University of Pennsylvania, "Managing Fibrodysplasia Ossificans Progressiva (FOP): Therapeutic Advances"

June 29, 2022

Ottman Tertuliano PhD, Assistant Professor of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, "Probing site-specific nanoscale mechanics of mineralized tissue"

May 25, 2022

Dirk Hubmacher PhD, Assistant Professor of Orthopaedics, Icahn School of Medicine at Mount Sinai, "Extracellular regulation of Wnt signaling by ADAMTS-like 2 in skeletal muscle"

April 27, 2022

Dongsu Park, PhD, Assistant Professor of Molecular and Human Genetics, Baylor College of Medicine, University of Pennsylvania, "Stem Cell Heterogeneity and Specific Regulation For Bone and Tendon Regeneration"

March 23, 2022

Kyla Ovtved, DVM, PhD, DACVS, DACVSMR, Jacques Jenny Endowed Term Chair of Orthopedic Surgery, Department of Clinical Studies-New Bolton Center, University of Pennsylvania, "Using cell and gene-based therapies to prevent posttraumatic osteoarthritis"

February 23, 2022

Elizabeth Bradley, PhD, Assistant Professor of Orthopaedics, University of Minnesota, "Macrophages in Bone Remodeling"

January 26, 2022

Whasil Lee, PhD, Assistant Professor of Biomedical Engineering, University of Rochester Medical Center, "Multifaceted Roles of Piezo Mechanosensitive Channels in Chondrocytes"

December 8, 2021

Zhiliang Cheng, PhD, University of Pennsylvania, "Engineering Nanoparticles for the Treatment of Osteoarthritis"

October 27, 2021

Nadeen Chahine, PhD, Columbia University, "Inflammation in the Degeneration and Repair of the Intervertebral Disc"

September 22, 2021

Prashant Chandrasekaran, PhD, Children’s Hospital of Philadelphia, "Indispensable roles of type V collagen in regulating TMJ condylar cartilage matrix growth and remodeling"

September 22, 2021

Chao Song, PhD, Children’s Hospital of Philadelphia, "Fatty acid metabolism in osteoclasts"

July 28, 2021

Philipp Leucht, MD, PhD, NYU Langone Health, "Hox Genes and Skeletal Stem Cell Maintenance"

June 30, 2021

Nelly Andarawis-Puri, PhD, Cornell University, "Reversing Accumulation of Tendon Damage and Enhancing Healing of Ruptured Tendons"

May 26, 2021

Benjamin Sinder, PhD, Children’s Hospital of Philadelphia, "Two strategies to cure (treat) one rare bone disease:  Can we be unbreakable?"

April 28, 2021

Spencer Szczesny, PhD, Pennsylvania State University, "The Role of Mechanical Stimulation in Late Tendon Development"

March 24, 2021

Sarah Gullbrand, PhD, University of Pennsylvania, "Intervertebral Disc Degeneration and Regeneration: A Motion Segment Perspective"

February 24, 2021

Bing Wang, MD, PhD, University of Pittsburgh, "Gene- and Cell-Activated Biomaterial Scaffold for Bone Tissue Engineering"

January 27, 2021

Makarand Risbud, PhD, Thomas Jefferson University, "Insights into intervertebral disc degeneration phenotypes - Lessons learned from inbred mouse strains"

December 2, 2020

Alesha Castillo, PhD, New York University, "Regulatory mechanisms in load-induced osteogenesis"

October 28, 2020

Jing Du, PhD, Penn State University, "Imaging-based experiments and modeling for bone-implant biomechanics"

September 23, 2020

Kang Ko, University of Pennsylvania, "NF-κB dysregulation in skeletal stem cells prevents resolution of inflammation during diabetic fracture healing"

September 23, 2020

Marco Angelozzi, PhD, Children’s Hospital of Philadelphia, "Key roles for SOXC transcription factors in calvariogenesis"

August 26, 2020

Kyu-Sang Joeng, PhD, University of Pennsylvania, "The function of mTORC1 signaling in postnatal tendon development and healing"

June 25, 2020

Kristy Weber, MD, University of Pennsylvania, "Bone Sarcomas: Kids, Dogs, and the Future"

May 27, 2020

Su Chin Heo, PhD, University of Pennsylvania, "Nuclear Mechanobiology: Why it Matters to Musculoskeletal Repair"

April 22, 2020

Alice Huang, PhD, Icahn School of Medicine at Mount Sinai, "Regulation of tendon regeneration"

March 25, 2020

Kyu-Sang Joeng, PhD, University of Pennsylvania, "The function of mTORC1 signaling in postnatal tendon development and healing"

February 26, 2020

Chitra Dahia, PhD, Weill Cornell Medicine, Hospital for Special Surgery, "Role of Sonic Hedgehog Signaling in the Regulation of Intervertebral Disc Growth and Differentiation"

January 29, 2020

Eileen Shore, PhD, University of Pennsylvania, "Heterotopic ossification and FOP: How does one tissue become another?"

December 11, 2019

Warren Grayson, PhD, Johns Hopkins University, "Functional Regeneration of Craniofacial Bone and Skeletal Muscle"

October 30, 2019

Sarah E. Catheline, PhD, Children's Hospital of Philadelphia, "Sustained IKKβ activation in postnatal chondrocytes accelerates the onset of age-associated murine osteoarthritis"

October 30, 2019

Ranjan Kc, PhD, Children's Hospital of Philadelphia, "Maintenance of growth plate and articular chondrocyte phenotype by SOX9"

September 25, 2019

George Dodge, PhD, University of Pennsylvania, "New Approaches to Therapeutic Discovery & Delivery"

August 28, 2019

Riccado Gottardi, PhD, Children's Hospital of Philadelphia, "Loads and signaling for cartilage regeneration"

July 31, 2019

Megan Killian, PhD, University of Delaware, "Growth and remodeling of musculoskeletal interfaces"

May 29, 2019

Josh Baxter, PhD, University of Pennsylvania, "Applied biomechanics to improve treatment options for Achilles tendon ruptures"

April 24, 2019

Fanxin Long, PhD, Children's Hospital of Philadelphia, "Growth factor and metabolic regulation of bone formation"

March 27, 2019

Mary Barbe, PhD, Temple University, "Blocking Substance P signaling reduces tissue fibrosis and improves sensorimotor declines in a rat model of overuse injury"

February 27, 2019

Michael Hast, PhD, University of Pennsylvania, "Macroscopic In Vitro, In Silico, and In Vivo Models of Shoulder Reconstructions"

January 23, 2019

Veronique Lefebvre, PhD, Children’s Hospital of Philadelphia, "Deciphering the molecular basis of SOXopathies, developmental
syndromes due to mutations affecting SOX transcription factor activities"

November 28, 2018

Xin Li, PhD, New York University, "Altered bone metabolism by hyperglycemia: a new function of an old metabolite"

October 31, 2018

Jormay Lim, PhD, University of Pennsylvania, "Primary cilia are essential for cell alignment and polarity during bone development through regulating Ceramide-PKCz apicobasal polarity signaling"

Christina Mundy, PhD, Children’s Hospital of Philadelphia, "Potential therapeutic targets to reduce osteochondromas in patients with Hereditary Multiple Exostoses"

October 4, 2018

Brya Matthews, PhD, University of Auckland, "Identification of periosteal progenitors involved in bone healing"

September 26, 2018

Anh Le, DDS, PhD, Penn Dental Medicine, "Large Gap Peripheral Nerve Regeneration with Orofacial Stem Cells Based Nerve Guidance Conduits"

August 29, 2018

David Paglia, PhD, Rutgers University, "Insulin-mimetic salt induces of bone formation and inhibits osteoclast differentiation and fusion to restore cortical porosity in a type I diabetic-induced osteolysis rat model"

June 19, 2018

Andrew Kuntz, MD, University of Pennsylvania, "Rotator Cuff Repair - From Bench to Bedside, Challenges and Opportunities"

May 30, 2018

Noriaki Ono, DDS, PhD, University of Michigan School of Dentistry, "Skeletal/mesenchymal stem cells: how much do we know about them? A lineage-tracing perspective"

April 25, 2018

Joel Boerckel, PhD, University of Pennsylvania, "Forceful feedback: mechanosensation in cell motility and morphogenesis"

March 28, 2018

Christopher Price, PhD, University of Delaware, "New Therapeutic Strategies for Preventing Cartilage Degeneration and Post-Traumatic Osteoarthritis"

February 21, 2018

Maurizio Pacifici, PhD, Children’s Hospital of Philadelphia, "Morphogenesis of articular cartilage: implications for repair strategies"

January 17, 2018

Scott Levin, MD, FACS, University of Pennsylvania, "Hand transplantation: current challenges and future prospects"

November 29, 2017

Nancy Pleshko, PhD, Temple University, "Novel Spectroscopic Imaging Tools for Assessment of Musculoskeletal Tissues"

October 25, 2017

Ryan Tomlinson, PhD, Thomas Jefferson University, "Inflammatory Signals in Stress Fracture Risk and Repair"

September 28, 2017

Danielle Rux, PhD, Children’s Hospital of Philadelphia, "Hox Genes in the Adult Skeleton: Patterning Cues Beyond Embryonic Development"

September 28, 2017

Xia Zhao, University of Pennsylvania, "In vivo Bone Quality Assessment by Phosphorus and Proton MRI"

August 30, 2017

Michael Levine, MD, MACE, FAAP, FACP, Children’s Hospital of Philadelphia, "Vitamin D deficiency in the 21st Century: New Insights into an Old Problem"

June 28, 2017

Mei Wan, PhD, Johns Hopkins University School of Medicine, "Mechanisms of PTH Bone Anabolic Action - New Perspectives On An Old Topic"

May 24, 2017

Li-Hsin (Leo) Han, PhD, Drexel University, College of Engineering, "Micro-noodles" for Cartilage Repair: A Strategy to Achieve Tunable Cell shape, Mechanosensing, and ECM organization in 3-D"

April 14, 2017

Li Zeng, PhD, Tufts University School of Medicine, "Regulators of cartilage development and maintenance"

March 28, 2017

Louis Soslowsky, PhD, University of Pennsylvania, "Tendon Healing in a Rotator Cuff Animal Model"

February 22, 2017

Noreen Hickok, PhD, Thomas Jefferson University, "Infections in synovial fluid: new challenges"

January 24, 2017

Nat Dyment, PhD, University of Pennsylvania, "Defining the lineage of tendon and ligament cells"

December 7, 2016

Shuying Yang, PhD, University of Pennsylvania, School of Dental Medicine, "Mechanism of Ciliary Intraflagellar Transport Protein in Bone Formation"

November 2, 2016

Simon Tang, PhD, Washington University in St. Louis, "Multiscale Mechanisms of Low Back Pain"

September 28, 2016

Chamith Rajapske, PhD, University of Pennsylvania, "Recent Developments in Imaging Techniques for Evaluation of Bone Disorders"

July 27, 2016

Harvey Smith, MD, University of Pennsylvania, "Applied MRI Quantitative Imaging Sequences and Tissue Engineering for the Treatment of Intervertebral Disc Degeneration"

June 6, 2016

Chi-der Chen, PhD, University of Pennsylvania, School of Dental Medicine, "Mesenchymal stem cell transplantation identifies miR151-5p as a therapeutic target for systemic sclerosis"

June 6, 2016

Satoru Otsuru, PhD, Nationwide Children's Hospital, "Understanding the mechanism of bone growth after MSC infusion"

May 25, 2016

Carla Scanzello, MD, PhD, University of Pennsylvania, "Inflammatory pathway activation in osteoarthritis: insights from patients and animal models"

April 27, 2016

Andrzej Fertala, PhD, Thomas Jefferson University, "Prevention of the Post-traumatic Fibrotic Response in Joints"

March 23, 2016

Herb Sun, PhD, Albert Einstein College of Medicine, "The role of CITED2 in cartilage and tendon: A basic study searching for translation"

February 24, 2016

Eiki Koyama, DDs, PhD, Children's Hospital of Philadelphia, "The roles of Indian hedgehog in temporo-mandibular joint (TMJ) development and postnatal function"

January 27, 2016

Jason Burdick, PhD, University of Pennsylvania, "Engineering Hydrogels for Cartilage Repair"

Dec 2, 2015

Yeijia Zhang, PhD, University of Pennsylvania, "Intervertebral disc degeneration and repair"

October 28, 2015

Foteini Mourkioti, PhD, University of Pennsylvania, "Regenerative stem cell therapies to restore diseased skeletal muscles"

September 23, 2015

Yu Usami, Children's Hospital of Philadelphia, "Contribution of Wnt/b-catenin-Responsive Cells to Articular and Growth Plate Cartilage Growth"

September 23, 2015

Jason Ashley, PhD, University of Pennsylvania, "Modulation of osteoclast function: finding a niche in Notch signaling"

August 26, 2015

Samir Mehta, MD, University of Pennsylvania, "Trying to Make Sense of it All:The Regulation of Fracture Healing in a Trauma Setting"

July 29, 2015

Lin Han, PhD, Drexel University, "Nanomechanics: A Novel Interdisciplinary Tool to Uncover the Pathogenesis of Osteoarthritis"

June 24, 2015

Abhishek Chandra, PhD, University of Pennsylvania, "Radiotherapy Induced Bone Damage: Basics to Therapeutics"

June 24, 2015

Chantal de Bakker, University of Pennsylvania, "Effects of Pregnancy, Lactation, and Weaning on Maternal Bone Quality"

May 27, 2015

Sunday Akintoye, BDS, DDS, MS, University of Pennsylvania, School of Dental Medicine, " Skeletal Stem Cells: is the jaw bone connected to the hip bone?"

April 22, 2015

Lacklan Smith, PhD, University of Pennsylvania, "Unraveling the Etiology of Spine Disease in Mucopolysaccharidosis Disorders"

March 18, 2015

Mindy George-Weinstein, PhD, Cooper Medical School of Rowan University, "Roles of Myo/Nog Cells in Embryogenesis, Wound Healing and Neuroprotection"

Februay 25, 2015

Liyun Wang, PhD, University of Delaware, "Osteocyte’s hairy pericellular matrix in mechanosensing"

December 10, 2014    

Songtao Shi, DDS, MS, PhD, University of Pennsylvania, School of Dental Medicine, "Mesenchymal stem cells: from clinics to bench-top and back"

October 22, 2014

Federica Sgariglia, PhD, Children’s Hospital of Philadelphia, "Previously unsuspected defects in the cranial base of a mouse model of Hereditary Multiple Exostoses"

October 22, 2014

Brianne Connizzo, University of Pennsylvania, "In situ fibril stretch and sliding is location-dependent in mouse supraspinatus tendons"

September 24, 2014 

X. Lucas Lu, PhD, University of Delaware, "Prevention and Treatment of Post-traumatic Osteoarthritis"

August 13, 2014  

Jaimo Ahn, MD, PhD, FACS, University of Pennsylvania, "Enhancing fracture healing: lessons from our rodent friends"

June 25, 2014 

Girish Ramaswamy, PhD, University of Pennsylvania, "GNAS inactivation in Progressive Osseous Heteroplasia (POH) and skeletal development"

June 25, 2014 

Spencer Szczesny, University of Pennsylvania, "GNAS inactivation in Progressive Osseous Heteroplasia (POH) and skeletal development"

May 28, 2014  

Masahiro Iwamoto, PhD, DDS, Children's Hospital of Philadelphia, "Specification and maintenance of permanent articular cartilage"

April 30, 2014    

Elisabeth Barton, PhD, University of Pennsylvania, School of Dental Medicine, "Forces and factors from muscle that modulate bone"

March 26, 2014  

Dana Graves, DDS, DMSc, University of Pennsylvania, School of Dental Medicine, "Osteoblastic cells regulate the response of bone to inflammation"

Februay 26, 2014  

Theresa Freeman, PhD, Thomas Jefferson University, "Regeneration - ASK1, can it provide some answers?"

January 15, 2014    

Robert Mauck, PhD, University of Pennsylvania, "Material and Mechanobiologic Considerations for Engineering Dense Connective Tissues"

Institute for Regenerative Medicine (IRM) Advances in Musculoskeletal Regeneration Seminars

June 7, 2024

Will Wang Ph.D., Assistant Professor at the Sanford Burnham Prebys Medical Discovery Institute, San Diego, “Spatial-omics revelations in muscle regeneration and aging"

March 19, 2024

Alexander Robling, MA, Ph.D., Chair of Anatomy, Cell Biology & Physiology. Acting Chair of Pharmacology & Toxicology, and Vincent H. Gattone II Professor of Anatomy & Cell Biology from Indiana University, School of Medicine, “Bone Building Molecular Targets: Lessons from Mechanical Signaling in Skeletal Tissues"

February 16, 2024

Elizabeth Barton, Ph.D., Associate Dean for Faculty and Staff Affairs, Professor of Applied Physiology and Kinesiology, University of Florida, “Requirements of Insulin-like growth factor I sources and forms for skeletal muscle regeneration

January 23, 2024

Se-Jin Lee, Ph.D., Professor, The Jackson Laboratory and a Presidential Distinguished Professor from the University of Connecticut School of Medicine, “Myostatin: A Molecular Rheostat for Muscle Mass”

December 15, 2023

Yangzi Yang, Ph.D., Associate Dean of Research, Professor of Developmental Biology, Harvard School of Dental Medicine, “A central role of mechanotransduction in controlling Shh expression via Yap activation in both regeneration and embryonic development

November 17, 2023

Woojin Hang, Ph.D., Assistant Professor of Orthopaedic Surgery at Icahn School of Medicine, Mount Sinai, “Bioengineering Strategies for Augmenting Skeletal Muscle Function in Rotator Cuff Injuries

October 27, 2023

Young Jang, Ph.D., Associate Professor of Orthopaedics at Emory School of Medicine and Georgia Institute of Technology, “Integrative bioengineering approaches to rejuvenate aging skeletal muscle

September 19, 2023

Tristan Maerz, Ph.D., Assistant Professor of Orthopaedic Surgery and Biomedical Engineering, University of Michigan, “Mechanisms of synovial fibrosis in post-traumatic osteoarthritis.

May 23, 2023

Michael Zuscik, M.D., Ph.D. University of Colorado, “Thinking Outside the Joint: Can Targeting the Intestine Support OA Disease Modification?”

April 14, 2023

Gabrielle Kardon, PhD, University of Utah, “From stem cells to a functional muscle: cellular dynamics of muscle regeneration”

March 31, 2023

Dianne Little BVSc PhD MRCVS DACVS, Associate Professor, Department of Basic Medical Sciences, Purdue University College of Veterinary Medicine, “Non-Wovens for Rotator Cuff Tendon Tissue Engineering, but for Whom?

January 24, 2023

Ralph Marcucio PhD, Professor of Orthopaedic Surgery and Director for the Laboratory for Skeletal Regeneration; Orthopaedic Trauma Institute, San Francisco General Hospital, from University of California San Francisco, “Life, Death and Transformation in the Transition Zone, Implications for Bone Healing”

December 9, 2022

Ben Cosgrove PhD, Associate Professor of Biomedical Engineering, Cornell University, “Multi-cellular coordination of stem cell regulation in skeletal muscle regeneration and aging

November 4, 2022

Robert Bowles PhD, Research Director of Orthopaedic Surgery, Associate Professor of Biomedical Engineering, University of Utah, “CRISP for Discovery, Design, and Development of Musculoskeletal Therapeutics

October 7, 2022

Pathak Medha PhD, Assistant Professor at the Department of Physiology and Biophysics, Sue and Bill Gross Stem Cell Research Center, University of California Irvine, “Molecular Choreography of Piezo1 in Development and Repair

May 6, 2022

Teresa Zimmers, PhD, HH Greg Professor of Cancer Research, at Richard L. Roudebush, VA Medical Center, Indianapolis, “Mechanisms of skeletal muscle wasting in reparative and pathological regeneration

April 15, 2022

Brendon Baker, PhD, Department of Biomechanical Engineering, University of Michigan, Ann-Arbor, “Emerging models and mechanism of pulmonary fibrosis

March 4, 2022

Jason Doles, PhD, Mayo Clinic , “Impaired regeneration in models of skeletal muscle wasting”

February 18, 2022

April Pyle, PhD, UCLA , “Regulation of Human Myogenesis in Development and Disease”

December 14, 2021

Yunzhi (Peter) Yang, PhD, Stanford University, “Combining heat, light, and sound based biofabrications to address musculoskeletal tissue engineering challenges”

November 5, 2021

Niamh Nowlan, PhD, University College in Dublin, “How to grow an elbow?”

October 12, 2021

Joe Chakkalakal, PhD, University of Rochester Medical Center, “Skeletal muscle postnatal growth and regenerative decline with age”

September 14, 2021

George Christ, PhD, University of Virginia, “Biomanufacturing, Biomaterials and Biomechanics for Improved Treatment of Volumetric Muscle Loss Injuries”

May 21, 2021

Nadia Rosenthal, PhD, FMedSci, FAAHMS, Scientific Director of the Jackson Laboratories, “New strategies for accelerating regeneration”

April 23, 2021

Karyn Esser, PhD, University of Florida, "Clocks in muscle: why muscles care about time"

February 19, 2021

Alayna Loiselle, PhD, University of Rochester Medical Center, "Multi-modal and multi-scale identification of pro-fibrotic mechanisms of tendon healing"

November 6, 2020

Dada Pisconti, PhD,  Stony Brook University "No cell is an island: muscle stem cells and their niche in health and disease"

October 16, 2020

Chris Ward, PhD, University of Maryland "Functional deficits in skeletal muscle: A focus on microtubules and myofibrils"

February 25, 2020

Joseph Stains, PhD, University of Maryland "Microtubules, Osteocyte Mechanotransduction, and the Surprising Regulation of Sclerostin"

January 21, 2020

Corey Neu, PhD, University of Colorado, Boulder, "Imaging across scales: visualizing tissue to subcellular mechanobiology in cartilage health and disease"

December 6, 2019

Dawn Cornelison, PhD, University of Missouri, "A pillar of community (effect): Eph reverse signaling promotes myogenic differentiation during development and regeneration"

October 24, 2019

Tim Woodfield, PhD, University of Otago, "Designing Bioink and Bioreactor Platforms for Musculoskeletal Regenerative Medicine"

April 30, 2019

Michael Longaker, MD, MBA, FACS, Stanford University School of Medicine and Hagey Laboratory for Pediatric Regenerative Medicine, "Skeletal Stem Cells"

March 12, 2019

Johnna Temenoff, PhD, Georgia Institute of Technology and Emory University, "Biomaterials based strategies for repair of rotator cuff tendon and muscle"

February 12, 2019

Karl Kadler, PhD, University of Manchester, UK, "Circadian clock regulation of collagen homeostasis"

January 18, 2019

Pura Munoz-Canoves, PhD, Universitat Pompeu Fabra and ICREA, "Understanding muscle stem cell regenerative decline with aging"

December 7, 2018

Robert Krauss, PhD, Mount Sinai, "Niche regulation of muscle stem cell quiescence and activation"

November 9, 2018

Vittorio Sartorelli, MD, PhD, NIH/NIAMS, "Enhancing Expression by Enhancer RNAs"

May 8, 2018

Sara Wickström, MD, PhD, University of Helsinki, "Regulation of stem cell fate through niche-derived signals and mechanical forces"

April 24, 2018

Christopher Evans, PhD, Mayo Clinic, "Orthopedic Applications of Gene Therapy"

March 27, 2018

Eben Alsberg, PhD, Case Western Reserve University, "Modular inductive high-density cell culture systems for engineering complex tissues"

February 23, 2018

Nat Dyment, PhD, University of Pennsylvania, "Tenocytes, Tenoblasts, and Tenoclasts(?): Defining the Cell Types within Tendons"

February 23, 2018

Alex Hughes, PhD, University of Pennsylvania, "Testing the design rules of tissue curvature in development"

January 26, 2018

Bradley Olwin, PhD, University of Colorado, "How are Muscle Stem Cells Numbers Maintained?"

December 15, 2017

Ivo Kalajzic, PhD, University of Connecticut Health Center, "Identifying different Osteoprogenitors and Understanding Their Role in Bone Repair"

November 10, 2017

Jenna Galloway, PhD, Massachusetts General Hospital, Harvard Stem Cell Institute, "Insights into tendon developmental plasticity and regenerative biology using zebrafish and mice"

October 27, 2017

Srihari Sampath, MD, PhD, MPhil, Genomics Institute of the Novartis Research Foundation, "Skeletal muscle, from generation to regeneration"

September 12, 2017

Linda Sandell, PhD, Washington University, "Cartilage Repair and Osteoarthritis in Genetic Mouse Models"

June 7, 2017

Nidhi Bhutani, PhD, Stanford University, "Unlocking the Secrets of Young Cartilage to Enhance Regeneration and Repair"

May 9, 2017

Denis Guttridge, PhD, The Ohio State University College of Medicine, "NF-kB Signaling in Muscle Growth and Disease"

April 4, 2017

Laurie Goodrich, DVM, PhD, Colorado State University, College of Veterinary Medicine, "MSC’s and immunomodulation: are we moving closer to allogeneic use?"

February 17, 2017

Douglas Millay, PhD, University of Cincinnati, "Mechanisms and applications of muscle stem cell fusions"

January 20, 2017

April Craft, PhD, Boston Children's Hospital, "Potential Therapeutics Applications of Human Pluripotent Stem Cell-Derived Cartilage"

December 2, 2016

Steve Thomopoulos, PhD, Columbia University, "Biologically inspired solutions for attaching dissimilar materials"

November 4, 2016

Megan Killian, PhD, University of Delaware, "FGF signaling during development of musculoskeletal interfaces"

November 4, 2016

Evangelia Bellas, PhD, Temple University, "Adipose Tissue Engineering: The Big Picture"

October 12, 2016

Michael A. Rudnicki, OC, PhD, FRSC,University of Ottawa, "Molecular regulation of muscle stem cell function"

June 24, 2016

Andrew Brack, PhD, University of California, "Skeletal muscle stem cells: Regeneration and Aging"

May 17, 2016

Alessandra Sacco, PhD, Sanford Burnham Medical Research Institute, "Microenvironmental regulation of skeletal muscle stem cell function"

April 19, 2016

Charles Gershach, PhD, Duke University, "Genome and Epigenome Editing for Gene Therapy and Programming Cell Fate"

March 11, 2016

Eileen M. Shore, PhD, University of Pennsylvania and Maurizio Pacifici, PhD, Children’s Hospital of Philadelphia
"Heterotopic ossification, a disorder of mis-directed cell fates: pathogenesis and possible treatments"

January 29, 2016

Dennis E. Discher, PhD, University of Pennsylvania, "Matrix, Contractility, & Nucleus as a Polymeric Continuum: from striated muscle to immune therapy for solid tumors"

December 11, 2015

Penney Gilbert, PhD, University of Toronto, “Molecular consequences of biophysical changes in the muscle stem cell niche”

November 6, 2015

Fabio Rossi, MD, PhD, University of British Columbia, Vancouver, Canada, "Innate Immune Control of Fibrogenesis during Tissue Regeneration"

October 12, 2015

Robert E. Guldberg, PhD, Georga Institue of Technology, "The Perils and Promise of Regenerative Medicine: Emerging Trends"

Center for Molecular Biology Laboratory Seminars

All seminars are scheduled at the McKay Orthopaedic Research Laboratory Library 426A Stemmler Hall at 12:00 noon, unless otherwise noted. This seminar series is sponsored by the Center for Research in FOP and Related Disorders at the University of Pennsylvania. *Some speakers were supported through the Department of Genetics and the Department of Cell and Developmental Biology seminar program. Links to additional relevant seminars can be found at:


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