Greg Maislin

faculty photo

Greg Maislin, M.S., M.A.

Adjunct Professor of Medicine (Sleep Medicine)
Senior Fellow, School of Nursing, University of Pennsylvania
Department: Medicine

Contact information
Biomedical Statistical Consulting
1357 Garden Road
Wynnewood, PA 19096
Office: 610-645-5708
Fax: 610-645-5734
B.S. (Economics)
Wharton School, University of Pennsylvania, 1980.
M.S. (Operations Research)
Wharton School, University of Pennsylvania, 1982.
M.A. (Statistics)
Wharton School, University of Pennsylvania, 1984.
ABD (Statistics– completed Ph.D. coursework and exams)
Wharton School, University of Pennsylvania , 1986.
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Description of Research Expertise

Mr. Maislin has served as director of the biostatistics core for the Center for Sleep and Respiratory Neurobiology since 1990. He has collaborated with Dr. Pack and other center investigators for many years and has been involved in applying statistical methods to address sleep research questions since 1988. His current areas of interest in statistics include methods for randomized clinical trials, Bayesian biostatistics, propensity methods for non-randomized comparisons, and non-linear mixed models for longitudinal data. He is currently active in sleep research involving efficacy of CPAP treatment for apnea, population screening for apnea, excessive daytime sleepiness and insomnia in the elderly, differential vulnerability to partial and total sleep deprivation, and in the heritability of differential vulnerability to sleep deprivation and other sleep-related phenotypes.

Selected Publications

Brakenridge SC, Wilfret DA, Maislin G, Andrade KE, Walker V, May AK, Dankner WM, Bulger EM: Resolution of organ dysfunction as a predictor of long-term survival in necrotizing soft tissue infections: analysis of the AB103 clinical composite endpoint study in necrotizing soft tissue infections trial and a retrospective claims database-linked chart study. J Trauma Acute Care Surg 91(2): 384-392, Aug 2021.

Pack AI, Magalang UJ, Singh B, Kuna ST, Keenan BT, Maislin G: To RCT or not to RCT? Depends on the question. A response to McEvoy et al. Sleep 44(4): zsab042, Apr 2021 Notes: doi: 10.1093/sleep/zsab042.

Goldschmied JR, Lacourse K, Maislin G, Delfrate J, Gehrman P, Pack FM, Staley B, Pack AI, Younes M, Kuna ST, Warby SC: Spindles are highly heritable as identified by different spindle detectors. Sleep 44(4): zsaa230, Apr 2021 Notes: doi: 10.1093/sleep/zsaa230.

Mack CD, Pavesio A, Kelly K, Irwin DE, Maislin G, Jones J, Wester T, Zura R: Breaking barriers: studying fracture healing in the BONES program. J Orthop Trauma 35(Suppl 1): S22-S27, Mar 2021.

Xu L, Keenan BT, Maislin D, Gislason T, Benediktsdóttir B, Gudmundsdóttir S, Gardarsdottir M, Staley B, Pack FM, Guo X, Feng Y, Chahwala J, Manaktala P, Hussein A, Reddy-Koppula M, Hashmath Z, Lee J, Townsend RR, Schwab RJ, Pack AI, Kuna ST, Chirinos JA: Effect of obstructive sleep apnea and positive airway pressure therapy on cardiac remodeling as assessed by cardiac biomarker and magnetic resonance imaging in nonobese and obese adults. Hypertension 77(3): 980-992, Mar 2021.

Pack AI, Magalang UJ, Singh B, Kuna ST, Keenan BT, Maislin G: Randomized clinical trials of cardiovascular disease in obstructive sleep apnea: understanding and overcoming bias. Sleep 44(2): zsaa229, Feb 2021 Notes: doi: 10.1093/sleep/zsaa229.

Rizzatti FG, Mazzotti DR, Mindel J, Maislin G, Keenan BT, Bittencourt L, Chen NH, Cistulli PA, McArdle N, Pack FM, Singh B, Sutherland K, Benediktsdottir B, Fietze I, Gislason T, Lim DC, Penzel T, Sanner B, Han F, Li QY, Schwab R, Tufik S, Pack AI, Magalang UJ: Defining extreme phenotypes of OSA across international sleep centers. Chest 158(3): 1187-1197, Sep 2020.

Bulger EM, May AK, Robinson BRH, Evans DC, Henry S, Green JM, Toschlog E, Sperry JL, Fagenholz P, Martin ND, Dankner WM, Maislin G, Wilfret D, Bernard AC: A novel immune modulator for patients with necrotizing soft tissue infections (NSTI): results of a multicenter, phase 3 randomized controlled trial of Reltecimod (AB 103). Ann Surg 272(3): 469-478, Sep 2020.

Singh B, Maislin G, Keenan BT, McArdle N, Mazzotti DR, Magalang U, Pack AI: CPAP treatment and cardiovascular prevention: an alternate study design that includes excessively sleepy patients. Chest 157(4): 1046-1047, Apr 2020.

Kuna ST, Townsend RR, Keenan BT, Maislin D, Gislason T, Benediktsdóttir B, Gudmundsdóttir S, Arnardóttir ES, Sifferman A, Staley B, Pack FM, Guo X, Schwab RJ, Maislin G, Chirinos JA, Pack AI: Blood pressure response to treatment of obese vs non-obese adults with sleep apnea. J Clin Hypertens 21(10): 1580-1590, Oct 2019.

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Last updated: 08/23/2021
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