Kimberly M Christian, Ph.D.

faculty photo
Research Assistant Professor of Neuroscience
Department: Neuroscience
Graduate Group Affiliations

Contact information
Perelman School of Medicine
Department of Neuroscience
415 Curie Blvd, CRB 105A
1st Floor Clinical Research Building
Philadelphia, PA 19104
Office: 215-573-2147
B.A. (Philosophy)
University of California at Berkeley, 1993.
Ph.D. (Neuroscience)
University of Southern California, 2004.
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Selected Publications

Kim NS, Ringeling FR, Zhou Y, Nguyen HN, Temme SJ, Lin YT, Eacker S, Dawson VL, Dawson TM, Xiao B, Hsu KS, Canzar S, Li W, Worley P, Christian KM, Yoon KJ, Song H, Ming GL.: CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders. Biol Psychiatry May 2021.

Wang X, Ye F, Wen Z, Guo Z, Yu C, Huang WK, Rojas Ringeling F, Su Y, Zheng W, Zhou G, Christian KM, Song H, Zhang M, Ming GL.: Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Mol Psychiatry 26: 1346-1360, Apr 2021.

Kim NS, Wen Z, Liu J, Zhou Y, Guo Z, Xu C, Lin YT, Yoon KJ, Park J, Cho M, Kim M, Wang X, Yu H, Sakamuru S, Christian KM, Hsu KS, Xia M, Li W, Ross CA, Margolis RL, Lu XY, Song H, Ming GL.: Pharmacological rescue in patient iPSC and mouse models with a rare DISC1 mutation. Nat Commun 12: 1398, Mar 2021.

Schnoll JG, Temsamrit B, Zhang D, Song H, Ming GL, Christian KM.: Evaluating Neurodevelopmental Consequences of Perinatal Exposure to Antiretroviral Drugs: Current Challenges and New Approaches. J Neuroimmune Pharmacol 16: 113-129, Mar 2021.

Song G, Lee EM, Pan J, Xu M, Rho HS, Cheng Y, Whitt N, Yang S, Kouznetsova J, Klumpp-Thomas C, Michael SG, Moore C, Yoon KJ, Christian KM, Simeonov A, Huang W, Xia M, Huang R, Lal-Nag M, Tang H, Zheng W, Qian J, Song H, Ming GL, Zhu H.: An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Machinery for ZIKV and DENV Replication. Genomics Proteomics Bioinformatics Feb 2021.

Christian KM, Ming GL, Song H.: Adult neurogenesis and the dentate gyrus: Predicting function from form. Behav Brain Res 379: 112346, Feb 2020.

Jacob F, Salinas RD, Zhang DY, Nguyen PTT, Schnoll JG, Wong SZH, Thokala R, Sheikh S, Saxena D, Prokop S, Liu DA, Qian X, Petrov D, Lucas T, Chen HI, Dorsey JF, Christian KM, Binder ZA, Nasrallah M, Brem S, O'Rourke DM, Ming GL, Song H.: A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity. Cell 180: 188-204, Jan 2020.

Christian KM, Song H, Ming GL.: Using Two- and Three-Dimensional Human iPSC Culture Systems to Model Psychiatric Disorders. Adv Neurobiol 25: 237-257, 2020.

Kang E, Song J, Lin Y, Park J, Lee JH, Hussani Q, Gu Y, Ge S, Li W, Hsu KS, Berninger B, Christian KM, Song H, Ming GL.: Interplay between a Mental Disorder Risk Gene and Developmental Polarity Switch of GABA Action Leads to Excitation-Inhibition Imbalance. Cell Rep 28: 1419-1428, Aug 2019.

Christian KM, Song H, Ming GL.: Pathophysiology and Mechanisms of Zika Virus Infection in the Nervous System. Annu Rev Neurosci 42: 249-269, Jul 2019.

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Last updated: 08/31/2021
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