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Jay Schneider, PhD
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Adjunct Professor of Pharmacology
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Department: Systems Pharmacology and Translational Therapeutics
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Contact information
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Thomas Jefferson University
39 Department of Pathology, Anatomy and Cell Biology
3e 1020 Locust Street, JAH 521
Philadelphia, PA 19107
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39 Department of Pathology, Anatomy and Cell Biology
3e 1020 Locust Street, JAH 521
Philadelphia, PA 19107
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Education:
21 9 B.A. 17 (Psychology) c
42 State University of New York, Stony Brook, 1977.
21 a Ph.D. 17 (Psychology) c
42 State University of New York, Stony Brook, 1981.
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Permanent link21 9 B.A. 17 (Psychology) c
42 State University of New York, Stony Brook, 1977.
21 a Ph.D. 17 (Psychology) c
42 State University of New York, Stony Brook, 1981.
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1e6 Schneider, J.S., Marshall, C.A., Keibel, L., Snyder, N.W., Hill, M.P., Brotchie, J.M., Johnston, T.H., Waterhouse, B., and Kortagere, S.: A novel Dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson's disease. Experimental Neurology 2021 Notes: https://doi.org/10.1016/j.expneurol.2020.113514.
db Barth, A.L., Schneider, J.S., Johnston, T.H., Hill, M.P., Brotchie, J.M., Moskal, J.R., Cearley, C.N.: NYX-458 improves cognitive performance in a primate Parkinson’s 70 disease model. Movement Disorders January 2020 Notes: https://doi.org/10.1002/mds.27962.
16d Neuwirth, L.S., Lopez, O.E., Schneider, J.S. and Markowitz, M.E.: Low-level lead exposure impairs fronto-executive functions: A call to update the DSM-V with lead poisoning as a neurodevelopmental disorder. Journal of Psychology & Neuroscience, 2020 Notes: https://doi.org/10.1037/pne0000225.
122 Magistretti, P.J., Geisler, F.H., Schneider, J.S., Li, A., Fiumelli, H., Sipione, S.: Gangliosides: Treatment avenues in neurodegenerative disease. Frontiers Neurology August 2019 Notes: doi: 10.3389/fneur.2019.00859.
11b Verma Megha, Schneider Jay S: siRNA-mediated knockdown of B3GALT4 decreases GM1 ganglioside expression and enhances vulnerability for neurodegeneration. Molecular and cellular neurosciences 95: 25-30, Jan 2019.
16e Schneider, J.S., Aras, R., Williams, C.K., Koprich, J.B., Brotchie, J.M., and Singh, V.: GM1 ganglioside modifies a-synuclein toxicity and is neuroprotective in a rat asynuclein model of Parkinson’s disease. Nature - Scientific Reports 2019 Notes: https://doi.org/10.1038/s41598-019-42847-x.
149 Guilarte, T.R., Yeh, C.-L., McGlothan, J.L., Perez, J., Finley, P., Zhou, Y., Wong, D.F.,Dydak, U., and Schneider, J.S.: PET imaging of dopamine release in the frontal cortex of manganese-exposed non-human primates. J. Neurochemistry 150(2): 188-201, 2019.
91 Singh, V., Aras, R., Singh, G., Schneider, J.S: M1 ganglioside as a modifier of alphasynuclein 38 toxicity in vivo and in cell culture. Neuroscience 6e Meeting Planner. Chicago, IL: Society for Neuroscience, Online.(Program No. 213.08), 2019.
86 Schneider, J.S., Singh, V.: Dysregulation of sphingolipid expression and metabolism b7 and its role in the pathogenesis of Parkinson's disease. Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience. Online(Program No. 213.01), 2019.
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Selected Publications
81 Schneider, J.S: A critical role for GM1 ganglioside in the pathophysiology and 94 potential treatment of Parkinson’s disease. Gylcoconjugate Journal 2021 Notes: https://doi.org/10.1007/s10719-021-10002-2.1e6 Schneider, J.S., Marshall, C.A., Keibel, L., Snyder, N.W., Hill, M.P., Brotchie, J.M., Johnston, T.H., Waterhouse, B., and Kortagere, S.: A novel Dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson's disease. Experimental Neurology 2021 Notes: https://doi.org/10.1016/j.expneurol.2020.113514.
db Barth, A.L., Schneider, J.S., Johnston, T.H., Hill, M.P., Brotchie, J.M., Moskal, J.R., Cearley, C.N.: NYX-458 improves cognitive performance in a primate Parkinson’s 70 disease model. Movement Disorders January 2020 Notes: https://doi.org/10.1002/mds.27962.
16d Neuwirth, L.S., Lopez, O.E., Schneider, J.S. and Markowitz, M.E.: Low-level lead exposure impairs fronto-executive functions: A call to update the DSM-V with lead poisoning as a neurodevelopmental disorder. Journal of Psychology & Neuroscience, 2020 Notes: https://doi.org/10.1037/pne0000225.
122 Magistretti, P.J., Geisler, F.H., Schneider, J.S., Li, A., Fiumelli, H., Sipione, S.: Gangliosides: Treatment avenues in neurodegenerative disease. Frontiers Neurology August 2019 Notes: doi: 10.3389/fneur.2019.00859.
11b Verma Megha, Schneider Jay S: siRNA-mediated knockdown of B3GALT4 decreases GM1 ganglioside expression and enhances vulnerability for neurodegeneration. Molecular and cellular neurosciences 95: 25-30, Jan 2019.
16e Schneider, J.S., Aras, R., Williams, C.K., Koprich, J.B., Brotchie, J.M., and Singh, V.: GM1 ganglioside modifies a-synuclein toxicity and is neuroprotective in a rat asynuclein model of Parkinson’s disease. Nature - Scientific Reports 2019 Notes: https://doi.org/10.1038/s41598-019-42847-x.
149 Guilarte, T.R., Yeh, C.-L., McGlothan, J.L., Perez, J., Finley, P., Zhou, Y., Wong, D.F.,Dydak, U., and Schneider, J.S.: PET imaging of dopamine release in the frontal cortex of manganese-exposed non-human primates. J. Neurochemistry 150(2): 188-201, 2019.
91 Singh, V., Aras, R., Singh, G., Schneider, J.S: M1 ganglioside as a modifier of alphasynuclein 38 toxicity in vivo and in cell culture. Neuroscience 6e Meeting Planner. Chicago, IL: Society for Neuroscience, Online.(Program No. 213.08), 2019.
86 Schneider, J.S., Singh, V.: Dysregulation of sphingolipid expression and metabolism b7 and its role in the pathogenesis of Parkinson's disease. Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience. Online(Program No. 213.01), 2019.
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