Faculty

Scott M. Damrauer, MD

faculty photo
William Maul Measey Associate Professor of Surgery II
Department: Surgery
Graduate Group Affiliations

Contact information
Division of Vascular Surgery
Hospital of the University of Pennsylvania
3400 Spruce Street, 14th Floor South Perelman Center
Philadelphia, PA 19104
Office: 215-615-1698
Fax: 215-614-0463
Education:
AB
Harvard College, Cambridge, MA, 1999.
MD
Harvard Medical School, Cambridge, MA, 2004.
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Selected Publications

1. Lee DSM, Cardone KM, Zhang DY, Tsao NL, Abramowitz S, Sharma P, DePaolo JS, Conery M, Aragam KG, Biddinger K, Dilitikas O, Hoffman-Andrews L, Judy RL, Khan A, Kullo IJ, Puckelwartz MJ, Reza N, Satterfield BA, Singhal P; Penn Medicine Biobank; Arany Z, Cappola TP, Carruth ED, Day SM, Do R, Haggerty CM, Joseph J, McNally EM, Nadkarni G, Owens AT, Rader DJ, Ritchie MD, Sun YV, Voight BF, Levin MG, Damrauer SM.: Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum. Nat Genet., Epub ahead of print. PMID: 40195560. April 2025.

Abramowitz SA, Levin MG, Damrauer SM.: Performance and Agreement of Coronary Heart Disease Polygenic Risk Scores-Reply. JAMA April 2025 Notes: Epub ahead of print. PMID: 40193127.

Murdock DR, Guo DC, DePaolo JS, Schwarze U, Duan XY, Cecchi AC, Marin IC, Tang Y, Chong JX, Bamshad MJ, Leppig KA, Byers PH, Damrauer SM, Milewicz DM. : Non-canonical splice variants in thoracic aortic dissection cases and Marfan syndrome with negative genetic testing. NPJ Genom Med. 10(1): 25, March 2025.

Neylan CJ, Levin MG, Hartmann K, Beigel K, Khodursky S, DePaolo JS, Abramowitz S, Furth EE, Heuckeroth RO, Damrauer SM, Maguire LH. : Genome-wide association meta-analysis identifies 126 novel loci for diverticular disease and implicates connective tissue and colonic motility. medRxiv [Preprint] March 2025.

Richardson TG, Urquijo H, Howe LJ, Hawkes G, DePaolo J, Damrauer SM, Frayling TM, Davey Smith G.: Effects of childhood and adult height on later life cardiovascular disease risk estimated through Mendelian randomization. Eur J Epidemiol. Epub ahead of print. PMID: 40106116 March 2025.

Suglia SF, Hidalgo B, Baccarelli AA, Cardenas A, Damrauer S, Johnson A, Key K, Liang M, Magnani JW, Pate B, Sims M, Tajeu GS; American Heart Association Social Determinants of Health Committee of the Council on Epidemiology and Prevention and Council on Quality of Care and Outcomes Research; Council on Cardiovascular and Stroke Nursing; Council on Genomic and Precision Medicine;Council on Hypertension; Council on Lifestyle and Cardiometabolic Health; and Council on Peripheral Vascular Disease.: Improving Cardiovascular Health Through the Consideration of Social Factors in Genetics and Genomics Research: A Scientific Statement From the American Heart Association. Circulation. Cardiovascular quality and outcomes Page: e000138, March 2025.

Yuan S, Chen J, Geng J, Zhao SS, Yarmolinsky J, Arkema EV, Abramowitz S, Levin MG, Tsilidis KK, Burgess S, Damrauer SM*, Larsson SC*.: GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosis. Nat Commun. 16(1): 2481, March 2025.

Yuan S, Khodursky S, Geng J, Sharma P, Spin JM, Tsao P, Levin MG, Damrauer SM.: Identifying Circulating Protein Mediators in the Link Between Smoking and Abdominal Aortic Aneurysm: An Integrated Analysis of Human Proteomic and Genomic Data. medRxiv [Preprint] 2025.02.27.25322973 March 2025.

Choi SH, Jurgens SJ, Xiao L, Hill MC, Haggerty CM, Sveinbjörnsson G, Morrill VN, Marston NA, Weng LC, Pirruccello JP, Arnar DO, Gudbjartsson DF, Mantineo H, von Falkenhausen AS, Natale A, Tveit A, Geelhoed B, Roselli C, Van Wagoner DR, Darbar D, Haase D, Soliman EZ, Davogustto GE, Jun G, Calkins H, Anderson JL, Brody JA, Halford JL, Barnard J, Hokanson JE, Smith JD, Bis JC, Young K, Johnson LSB, Risch L, Gula LJ, Kwee LC, Chaffin MD, Kühne M, Preuss M, Gupta N, Nafissi NA, Smith NL, Nilsson PM, van der Harst P, Wells QS, Judy RL, Schnabel RB, Johnson R, Smit RAJ, Gabriel S, Knight S, Furukawa T, Blackwell TW, Nauffal V, Wang X, Min YI, Yoneda ZT, Laksman ZWM, Bezzina CR, Alonso A, Psaty BM, Albert CM, Arking DE, Roden DM, Chasman DI, Rader DJ, Conen D, McManus DD, Fatkin D, Benjamin EJ, Boerwinkle E, Marcus GM, Christophersen IE, Smith JG, Roberts JD, Raffield LM, Shoemaker MB, Cho MH, Cutler MJ, Rienstra M, Chung MK, S Olesen M, Sinner MF, Sotoodehnia N, Kirchhof P, Loos RJF, Nazarian S, Mohanty S, Damrauer SM, Kaab S, Heckbert SR, Redline S, Shah SH, Tanaka T, Ebana Y; Regeneron Genetics Center; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Holm H, Stefansson K, Ruff CT, Sabatine MS, Lunetta KL, Lubitz SA, Ellinor PT.: Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk. Nature genetics 57(3): 548–562, March 2025.

Georgakis MK, Malik R, Bounkari OE, Hasbani NR, Li J, Huffman JE, Shakt G, Tack RWP, Kimball TN, Asare Y, Morrison AC, Tsao NL, Judy R, Mitchell BD, Xu H, Montasser ME, Do R, Kenny EE, Loos RJF, Terry JG, Carr JJ, Bis JC, Psaty BM, Longstreth WT, Young KA, Lutz SM, Cho MH, Broome J, Khan AT, Wang FF, Heard-Costa N, Seshadri S, Vasan RS, Palmer ND, Freedman BI, Bowden DW, Yanek LR, Kral BG, Becker LC, Peyser PA, Bielak LF, Ammous F, Carson AP, Hall ME, Raffield LM, Rich SS, Post WS, Tracy RP, Taylor KD, Guo X, Mahaney MC, Curran JE, Blangero J, Clarke SL, Haessler JW, Hu Y, Assimes TL, Kooperberg C, Bernhagen J, Anderson CD, Damrauer SM, Zand R, Rotter JI, de Vries PS, Dichgans M.: Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk. Genome Med. 17(1): 27, March 2025.

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Last updated: 04/21/2025
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