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Rebecca N. Ichord, MD

Professor of Neurology at the Children's Hospital of Philadelphia
Attending Neurologist, The Children's Hospital of Philadelphia
Director, Pediatric Stroke Fellowship Program, The Children's Hospital of Philadelphia
Director, Pediatric Stroke Program , The Children's Hospital of Philadelphia
Section Chief, ICU Neurology Consultation Service, The Children's Hospital of Philadelphia
Department: Neurology

Contact information
Dept. of Neurology
Children’s Hospital of Philadelphia
3400 Civic Center Blvd., 6th Floor
Philadelphia, PA 19104-4318
Office: 215-590-4142
Fax: 215-590-5120
B.S. (Biology, Magna cum laude)
University of Hawaii , 1975.
George Washington University School of Medicine (with distinction), 1979.
Post-Graduate Training
Resident & Chief Resident in Pediatrics, Children’s National Medical Center, Washington, D.C. , 1979-1983.
Clinical Fellow in Developmental Pediatrics, J.F.Kennedy Institute, Johns Hopkins Hospital, Baltimore, Md. , 1983-1985.
Resident and Chief Resident in Child Neurology, Johns Hopkins Medical Institutions, Baltimore, Md. , 1988-1991.
American Board of Pediatrics, 1984.
American Board of Psychiatry and Neurology, with expertise in Child Neurology, 1992.
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Description of Research Expertise

Clinical research is focused primarily on stroke in childhood, including arterial ischemic stroke, intracranial hemorrhage, cerebral venous thrombosis, and related cerebral vascular disorders. Current active research activities include an NIH-funded multicenter cohort study to evaluate safety/dose-finding for thrombolysis in pediatric stroke (TIPS); vascular effects of infection in pediatric stroke (VIPS); inflammatory coagulation markers in pediatric stroke; neurological manifestations of cerebral ischemic injury in sickle cell anemia (SITT and SWiTCH trials); a two-center cohort study of outcome predictors in childhood spontaneous intracranial hemorrhage; and a pilot study of treadmill training therapy in children recovering from stroke.

Related research activities through collaborations locally at CHOP/Penn and nationally include: hypothermia for pediatric cardiac arrest, and mechanisms of secondary injury in traumatic brain injury in children.

Description of Clinical Expertise

Childhood Stroke & acute brain injury due to cardiac arrest and traumatic brain injury. Primary clinical focus is stroke. As director of the CHOP Stroke Program, I oversee operation of clinical stroke care programs through a 24/7 rapid response neurovascular consultation service and multidisciplinary out-patient stroke follow-up clinic. The Stroke Program team includes expert care in neonatal stroke and cognitive effects of stroke by Dr. Lori Billinghurst, and effects of congenital heart disease on developing brain by Dr. Daniel Licht. Training elements include bedside & didactic teaching activities for physician and nursing staff within CHOP, and community outreach via a CME program for primary ED & pediatric practitioners. A pediatric stroke fellowship was established in July 2008.

Selected Publications

Jordan LC, Hills NK, Fox CK, Ichord RN, Pergami P, deVeber GA, Fullerton HJ, Lo W, and the VIPS Investigators : “Socioeconomic Determinants of Outcome after Childhood Arterial Ischemic Stroke” Neurology 91(6): e509-e516 Aug 2018.

Kirschen MP, Snyder M, Winters M, Ichord R, Berg R, Nadkarni V, Topjian A: “Survey of bedside neurologic assessments in U.S. pediatric intensive care units” Ped Crit Care Med 19(4): 339-344, April 2018.

DuPont-Thibodeau G, Fry M, Kirschen M, Abend NS, Ichord R, Nadkarni VM, Berg R, Alexis Topjian A: “Timing and Causes of Death after Out-of-Hospital Cardiac Arrest Resuscitation” Resuscitation in press, 2018.

Heather J. Fullerton HJ, Stence N, Hills NK, Jiang B, Amlie-Lefond C, Bernard TJ, Neil R. Friedman NR, Ichord R, Mackay MT, Rafay MF, Chabrier S, Steinlin M, Elkind MSV, DeVeber GA, Wintermark M, and the VIPS Investigators : “Focal Cerebral Arteriopathy of Childhood: Novel Severity Score and Natural History” Stroke in press, 2018.

Porcari GS, Beslow LA, Ichord RN, Licht DJ, Kleinman JT, Jordan LC : “Neurologic Outcome Predictors in Pediatric Intracerebral Hemorrhage: A Prospective Study” Stroke in press, 2018.

Ichord R, Silverstein FS, Slomine BS, Telford R, Christensen J, Holubkov R, PhD4, Dean JM, Moler FW for the THAPCA Trial Group : “Neurological Outcomes in Pediatric Cardiac Arrest Survivors Enrolled in the THAPCA Trials” Neurology in press, 2018.

Bosenbark DD, Krivitzky L, Ichord R, Vossough A, Bhatia A, Jastrzab LE, Billinghurst L: Clinical Predictors of Attention and Executive Functioning Outcomes in Children After Perinatal Arterial Ischemic Stroke. Ped Neurol 69: 79-86, Apr 2017.

Uohara MY, Beslow LA, Billinghurst L, Jones BM, Kessler SK, Licht DJ, Ichord, RN: Incidence of Recurrence in Posterior Circulation Childhood Arterial Ischemic Stroke: A Prospective Cohort Study. JAMA Neurology 74(3): 316-323, March 2017.

Petrov D, Uohara MY, Ichord R, Lang S-S, Ali Z, Jastrzab L, Billinghurst L : Pediatric Cerebral Sinovenous Thrombosis Following Cranial Surgery. Child’s Nervous System 33: 491-497, Mar 2017.

Billinghurst LL, Beslow LA, Abend NS, Uohara M, Jastrzab LE, Licht DJ, Ichord RN : Incidence and Predictors of Epilepsy after Pediatric Arterial Ischemic Stroke Neurology 88: 630-637, Feb 2017.

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Last updated: 09/01/2018
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