Rebecca N. Ichord, MD
Children’s Hospital of Philadelphia
3501 Civic Ctr Blvd
Philadelphia, PA 19104-4318
B.S. (Biology, Magna cum laude)
University of Hawaii , 1975.
George Washington University School of Medicine (with distinction), 1979.
Resident & Chief Resident in Pediatrics, Children’s National Medical Center, Washington, D.C. , 1979-1983.
Clinical Fellow in Developmental Pediatrics, J.F.Kennedy Institute, Johns Hopkins Hospital, Baltimore, Md. , 1983-1985.
Resident and Chief Resident in Child Neurology, Johns Hopkins Medical Institutions, Baltimore, Md. , 1988-1991.
American Board of Pediatrics, 1984.
American Board of Psychiatry and Neurology, with expertise in Child Neurology, 1992.
Description of Research ExpertiseClinical research is focused primarily on stroke in childhood, including arterial ischemic stroke, intracranial hemorrhage, cerebral venous thrombosis, and related cerebral vascular disorders. Current active research activities include an NIH-funded multicenter cohort study to evaluate safety/dose-finding for thrombolysis in pediatric stroke (TIPS); vascular effects of infection in pediatric stroke (VIPS); inflammatory coagulation markers in pediatric stroke; neurological manifestations of cerebral ischemic injury in sickle cell anemia (SITT and SWiTCH trials); a two-center cohort study of outcome predictors in childhood spontaneous intracranial hemorrhage; and a pilot study of treadmill training therapy in children recovering from stroke.
Related research activities through collaborations locally at CHOP/Penn and nationally include: hypothermia for pediatric cardiac arrest, and mechanisms of secondary injury in traumatic brain injury in children.
Description of Clinical ExpertiseChildhood Stroke & acute brain injury due to cardiac arrest and traumatic brain injury. Primary clinical focus is stroke. As director of the CHOP Stroke Program, I oversee operation of clinical stroke care programs through a 24/7 rapid response neurovascular consultation service and multidisciplinary out-patient stroke follow-up clinic. The Stroke Program team includes expert care in neonatal stroke and cognitive effects of stroke by Dr. Lori Billinghurst, and effects of congenital heart disease on developing brain by Dr. Daniel Licht. Training elements include bedside & didactic teaching activities for physician and nursing staff within CHOP, and community outreach via a CME program for primary ED & pediatric practitioners. A pediatric stroke fellowship was established in July 2008.
Selected PublicationsMeert K, Slomine BS, Silverstein FS, Christensen J, Ichord R, Telford R, Holubkov R, Dean JM, Moler FW; Therapeutic Hypothermia after Paediatric Cardiac Arrest (THAPCA) Trial Investigators : ”One-year cognitive and neurologic outcomes in survivors of paediatric extracorporeal cardiopulmonary resuscitation.” Resuscitation 139: 299-307, June 2019.
Guilliams KP, Kirkham FJ, Holzhauer S, Pavlakis S, Philbrook B, Amlie-Lefond C, Noetzel MJ, Dlamini N, Sharma M, Carpenter JL, Fox CK, Torres M, Ichord RN, Jordan LC, Dowling MM : “Arteriopathy influences pediatric ischemic stroke presentation, but sickle cell disease influences stroke management” Stroke 50(5): 1089-1094, May 2019.
Kirschen MP, Snyder M, Smith K, Lourie K, Agarwal K, DiDonato P, Doll A, Zhang B, Mensinger J, Ichord R, Shea JA, Berg RA, Nadkarni V, Topjian A : “Inter-Rater Reliability Between Critical Care Nurses Performing a Pediatric Modification to the Glasgow Coma Scale.” Pediatr Crit Care Med Page: Epub ahead of print, Apr 2019.
Krivitzky L, Bosenbark DD, Ichord R, Jastrzab L, Billinghurst L.: “Brief report: Relationship between performance testing and parent report of attention and executive functioning profiles in children following perinatal arterial ischemic stroke.” Child Neuropsychol 25: 1-9, March 2019.
Kirschen MP, Francoeur C, Murphy M, Traynor D, Zhang B, Mensinger JL, Ichord R, Topjian A, Berg RA, Nishisaki A, Morrison W. : “Epidemiology of Brain Death in Pediatric Intensive Care Units in the United States.” JAMA Pediatr Page: epub ahead of print, Mar 2019.
Kirschen MP, Blinder J, Dewitt A, Snyder M, Ichord R, Berg RA, Nadkarni V, Topjian A: “Bedside clinical neurologic assessment utilisation in paediatric cardiac intensive care units.” Cardiol Young 28(12): 1457-1462, Dec 2018.
Heather J. Fullerton HJ, Stence N, Hills NK, Jiang B, Amlie-Lefond C, Bernard TJ, Neil R. Friedman NR, Ichord R, Mackay MT, Rafay MF, Chabrier S, Steinlin M, Elkind MSV, DeVeber GA, Wintermark M, and the VIPS Investigators : “Focal Cerebral Arteriopathy of Childhood: Novel Severity Score and Natural History” Stroke 49(11): 2590-96, Nov 2018.
Jordan LC, Hills NK, Fox CK, Ichord RN, Pergami P, deVeber GA, Fullerton HJ, Lo W, and the VIPS Investigators : “Socioeconomic Determinants of Outcome after Childhood Arterial Ischemic Stroke” Neurology 91(6): e509-e516 Aug 2018.
DuPont-Thibodeau G, Fry M, Kirschen M, Abend NS, Ichord R, Nadkarni VM, Berg R, Alexis Topjian A: “Timing and Causes of Death after Out-of-Hospital Cardiac Arrest Resuscitation” Resuscitation 133: 160-166, Aug 2018.
Porcari GS, Beslow LA, Ichord RN, Licht DJ, Kleinman JT, Jordan LC : “Neurologic Outcome Predictors in Pediatric Intracerebral Hemorrhage: A Prospective Study” Stroke 49(7): 1755-1758, July 2018.