faculty photo

Sami L. Khella

Professor of Clinical Neurology
Attending Neurologist, Penn Presbyterian Medical Center
Attending Physician, Penn Presbyterian Medical Center
Director of Clinical Electrophysiology, Penn Prebyterian Medical Center
Director Clinical Neurophysiology, Penn Presbyterian Medical Center
Attending Physician, Hospital of the University of Pennsylvania
Chief Department of Neurology Penn Presbyterian , University of Pennsylvania
Department: Neurology

Contact information
Penn Presbyterian Medical Center
Suite 305 Medical Office Building
3900 Market St
Philadelphia, PA 19104
Office: 215-662-8870
Fax: 215-222-1856
B.A. (Biology)
University of Pennsylvania , 1979.
University of Pennsylvania, 1984.
Post-Graduate Training
Intern Internal Medicine, Penn Presbyterian Medical Center, 1984-1985.
Resident Internal Medicine, Penn Presbyterian Medical Center, 1985-1986.
Resident Neurology, University of Pennsylvania, 1986-1989.
MDA Fellow Neuromuscular Diseases, University of Pennsylvania, 1989-1990.
American Academy of Neurology, 1990.
American Board of Electrodiagnostic Medicine, 1993.
Amnerican Academy of Neurology - Added qualifications in Electrophysiology, 1997.
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Description of Research Expertise

I participate in clinical trials on amyloidosis, myasthenia gravis, chronic inflammatory polyneuropathy and guillain barre syndrome

Description of Clinical Expertise

I have more than 20 years experience in diagnosing and treating patients with a variety of neurologic diseases. As a neuromuscular specialist,
I perform electromyography and interpret evoked potentials.

As a treating physician, I focus on the treatment of patients with myasthenia gravis. I am also interested in measuring quality of life in this illness and how it improves with treatment.

I co-founded the Penn Amyloidosis Center. This is one of the largest multidisciplinary programs in the United States treating patients with hereditary and acquired amyloidosis. We are a group that is active in clinical trials and cutting edge therapies for this group of diseases.

My other interests includes treating patients with acquired inflammatory neuropathies, such as chronic inflammatory demyelinating polyneuropathy (CIDP),and myopathies such as polymyositis and dermatomyositis.

Selected Publications

Khella, Sami: Artist's statement: Woe. Academic Medicine 85(9): 1404, Sep 2010.

Souayah, Nizar. Khella, Sami L.: A prospective double-blind, placebo-controlled study of thalidomide sensory symptoms in an elderly population with age-related macular degeneration. Journal of Clinical Neuroscience 17(5): 571-3, May 2010.

Wolraich, D. Vasile Marchis-Crisan, C. Redding, N. Khella, S L. Mirza, N.: Laryngeal tremor: co-occurrence with other movement disorders. Orl; Journal of Oto-Rhino-Laryngology & its Related Specialties 72(5): 291-4, 2010.

Khella, SL: New insights into stroke in chronic kidney disease. Advances in Chronic Kidney Disease 15(4): 338-46, Oct 2008.

Khella, Sami. Bleicher, Melissa B.: Stroke and its prevention in chronic kidney disease. [Review] [105 refs] Clinical Journal of The American Society of Nephrology: CJASN 2(6): 1343-51, Nov 2007.

Khella, Sami L. Souyah, Nizar. Dalmau, Josep.: Thymoma, myasthenia gravis, encephalitis, and a novel anticytoplasmic neuronal antibody. Neurology 69(12): 1302-3, Sep 18 2007.

Prasad, Sashank. El-Haddad, Ghassan. Zhuang, Hongming. Khella, Sami.: Intracranial hypotension following chiropractic spinal manipulation. Headache 46(9): 1456-8, Oct 2006.

Souayah, N. Sander, H W. Menkes, D L. Khella, S L.: Hepatitis C virus acute quadriparetic vasculitic neuropathy responsive to cyclophosphamide. Neurology, Neurophysiology, & Neuroscience Page: 5, 2006.

Souayah, N Khella, S: Neurology: Examination and Board Review. US. McGraw Hill, 2005.

Khella, S L.: Neurologic differential diagnosis in podiatry. [Review] [34 refs] North American Podiatric Clinics 16(1): 49-66, vi, Jan 1999.

Khella, S L. Kozart, D.: Unmasking and exacerbation of myasthenia gravis by ophthalmic solutions: betoxolol, tobramycin, and dexamethasone. A case report. Muscle & Nerve 20(5): 631, May 1997.

Khella, S L. Frost, S. Hermann, G A. Leventhal, L. Whyatt, S. Sajid, M A. Scherer, S S.: Hepatitis C infection, cryoglobulinemia, and vasculitic neuropathy. Treatment with interferon alfa: case report and literature review. [Review] [42 refs] Neurology 45(3 Pt 1): 407-11, Mar 1995.

Huang, J C. Gay, R. Khella, S L.: Sickling crisis, fat embolism, and coma after steroids. Lancet 344(8927): 951-2, Oct 1 1994.

Khella, S. Frederic, M.: Dropped head syndrome. Neurology 43(4): 846; author reply 846-7, Apr 1993.

S. Khella, B. Drachman,P. DiVitom M. Polydefkis, M. Maurerϧ : Neurologic Involvement in V 122 Ile Familial Amyloidosis. IXth International Symposium on Familial Amyloidotic Polyneuropathy 2013.

Iannotti JP, Hennigan S, Herzog R, Khella S, Kelley M, Leggin B, Williams GR: Latissimus dorsi tendon transfer for irreparable posterosuperior rotator cuff tears. Factors affecting outcome. J Bone Joint Surg Am 88(2), 2006.

Khella, SL: Electromyography in Shoulder Disorders. Orthopaedic Journal 2000.

Sagin T, Khella S, Ende J, Morgenstern D: Case #446—Parkinson’s disease. Med Cases online. http://www.medcases.com 2001.

Souyah N, Khella SL.: Low dose cyclosporine in myasthenia gravis. Short Report. Clin Neuromusc Dis 2006.

Khella SL. : Multiple sclerosis. http://www.medcases.com 2008.

Homma et al: Warfarin and Aspirin in Patients with Heart Failure and Sinus Rhythm. NEJM 366(20): 1859-69, May 2012.

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Last updated: 12/11/2023
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