Sabrina W. Yum, M.D.
3501 Civic Center Boulevard
Philadelphia, pa 19104
Guangzhou Medical College, 1983.
Postdoctoral Research Fellow, Center for Neural Injury, University of California, San Francisco/Veterans Administration Medical Center, 1985-1989.
Intern in Pediatrics , Albert Einstein College of Medicine/Montefiore Medical Center, NY, 1989-1990.
Resident in Pediatrics, Albert Einstein College of Medicine/Montefiore Medical Center, NY, 1990-1992.
Fellow in Pediatric Neurology, Dept. of Neurology at Johns Hopkins University School of Medicine , 1992-1995.
Fellow in Neuromuscular Diseases and EMG, Dept. of Neurology at University of Pennsylvania, 1995-1996.
USA Educational Commission for Foreign Medical Graduate Certificate ( No. 405-021-7) , 1987.
American Board of Pediatrics (No. 052501), 1993.
American Board of Psychiatry and Neurology, with special qualification in child neurology (No. 1065), 1997.
American Board of Psychiatry and Neurology, in the subspecialty of clinical Neurophysiology (No. 1211), 1999.
American Board of Psychiatry and Neurology, in the subspecialty of clinical Neurophysiology (No. 1211), re-certification , 2009.
American Board of Psychiatry and Neurology, in the subspecialty of Neuromuscular Medicine (No. 626) , 2012.
American Board of Psychiatry and Neurology, with special qualification in Child Neurology (No. 1065), re-certification, 2018.
Description of Research ExpertiseBiology and pathogenesis of connexin mutations associated with Charcot-Marie-Tooth disease, hearing loss
The role of neurofilaments in axonal degeneration
Pediatric neuromuscular disorders
clinical trials in pediatric neuromuscular diseases
Description of Clinical ExpertisePediatric Neurology
Pediatric Neuromuscular diseases
Brachial plexopathy, Erb's palsy
Nerve conduction study and EMG
BOTOX injection for patients with movement disorders and spasticity
Selected PublicationsAhrens-Nicklas RC, Pappas CT, Farman GP, Mayfield RM, Larrinaga TM, Medne L, Ritter A, Krantz ID, Murali C, Lin KY, Berger JH, Yum SW, Carreon CK, Gregorio CC: Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy. Sci Adv 5(9): eaax2066 September 2019.
Estilow T, Glanzman AM, Burns J, Harrington A, Cornett KMD, Menezes MP, Shy R, Moroni I, Foscan M, Pagliano E, Pareyson D, Bhandari T, Muntoni F, Laura M, Reilly MM, Finkel RS, Eichinger K, Herrmann DN, Troutman G, Bray P, Halaki M, Shy ME, Yum SW: Balance impairment in pediatric charcot–marie–tooth disease. Muscle & Nerve 60(3), Sep 2019.
Kim AG, Upah SA, Brandsema JF, Yum SW, Blinman TA: Thoracoscopic thymectomy for juvenile myasthenia gravis. Pediatr Surg Int 35(5): 603–610, May 2019.
Tao F, Beecham GW, Rebelo AP, Blanton SH, Moran JJ, Lopez-Anido C, Svaren J, Morrow JM, Abreu L, Rizzo D, Kirk CA, Wu X, Feely S, Verhamme C, Sporta MA, Herrmann DN, Day JW, Sumner CJ, Lloyd TE, Li J, Yum SW, Toroni F, Baas F, Choi Byung, Pareyson D, Scherer SS, Reilly MM, Shy ME, Zuchner S, for the inherited Neuropathy Consortium: Variation in SIPA1L2 is correlated with phenotype modification in CMT type 1A. Annals of Neurology 85(3): 316-330, Mar 2019.
Glanzman A, Yildiz S, Estilow T, Flickinger J, Brandsema JF, TEnnekoon G, Banwell BL,Yum SW: Retrospective analysis of fractures and factors causing ambulation loss after lower extremity fractures in Duchenne Muscular Dystrophy. AJPMR 2019.
Zingariello C, Brandsema J, Drum E, Henderson, A, Dubow S, Glanzman A, Mayer O, Yum SW, Kichula E : A multidisciplinary approach to dosing nusinersen for spinal muscular atrophy. Neurology 9: 424-432, 2019.
Estilow T, Beam M, Nardone M, Glanzman AM, Yum SW: Sensitivity of Clinically Assessed Measures of Balance and Computerized Dynamic Posturography in Pediatric Charcot-Marie-Tooth Disease. Presented in the 2019 Peripheral Nerve Society Meeting 2019.
Finkel R, Vandenborne KHE, Sweeney HL, Finanger E, Tennekoon G, Shieh P, Willcocks, RJ, Walter G, Rooney W, Forbes, SC, Triplett W, Yum SW, Mancini M, MacDougall J, Fretzen A, Bistra P, Nichols A, Donovan J: Edasalonexent, an NF-kB Inhibitor, Slows Longer-Term Disease Progression on Multiple Functional and MRI Assessments Compared to Control Period in 4 to 7-Year Old Patients with Duchenne Muscular Dystrophy Neurology 92 (15 supp), 2019 Notes: Presented in the 2019 American Academy of Neurology Annual Meeting.
Kichula E, Devanarayan P, Glanzman A, Estilow T, Yum SW, Brandsema J. : Motor Outcomes after Clinical Treatment with Nusinersen: A Single-center Experience. Neurology 92 (15 supp), 2019 Notes: Presented in the 2019 American Academy of Neurology Annual Meeting.
Finanger E, | Vandenborne K, Finkel, RS, Lee Sweeney H, Tennekoon, G, Yum SW, Mancini M, Bista P, Nichols A, Liu H, Fretzen A, Donovan JM: Phase 1 Study of Edasalonexent (CAT-1004), an Oral NF- κB Inhibitor, in Pediatric Patients with Duchenne Muscular Dystrophy. Journal of Neuromuscular Dis 6(1): 43-54 2019.