Mark P Fitzgerald, MD PhD
Associate Professor of Clinical Neurology
Attending Physician, Children's Hospital of Philadelphia, University of Pennsylvania
Department: Neurology
Contact information
3401 Civic Center Blvd
Division of Neurology
The Hub for Clinical Collaboration, 10553
Philadelphia, PA 19104
Division of Neurology
The Hub for Clinical Collaboration, 10553
Philadelphia, PA 19104
Office: 2155901719
Fax: 2155901771
Fax: 2155901771
Email:
fitzgeraldmp@chop.edu
fitzgeraldmp@chop.edu
Publications
Education:
BS (Psychology, Philosophy, Neuroscience)
University of Scranton, 2002.
PhD (Neuroscience)
University of Virginia, 2010.
MD (Medicine)
University of Virginia, 2011.
BS (Psychology, Philosophy, Neuroscience)
University of Scranton, 2002.
PhD (Neuroscience)
University of Virginia, 2010.
MD (Medicine)
University of Virginia, 2011.
Post-Graduate Training
Resident - Pediatrics, Children's Hospital of Philadelphia, 2011-2013.
Resident - Child Neurology, Children's Hospital of Philadelphia, 2013-2016.
Fellow - Epilepsy, Children's Hospital of Philadelphia, 2016-2017.
Resident - Pediatrics, Children's Hospital of Philadelphia, 2011-2013.
Resident - Child Neurology, Children's Hospital of Philadelphia, 2013-2016.
Fellow - Epilepsy, Children's Hospital of Philadelphia, 2016-2017.
Certifications
American Board of Psychiatry and Neurology - Child Neurology, 2016.
American Board of Psychiatry and Neurology – Epilepsy, 2017.
Permanent linkAmerican Board of Psychiatry and Neurology - Child Neurology, 2016.
American Board of Psychiatry and Neurology – Epilepsy, 2017.
Description of Clinical Expertise
Neonatal and early life epilepsies, Genetic epilepsyDescription of Research Expertise
I am interested in neurodevelopmental and epilepsy outcomes in patients with neonatal and early-onset epilepsy, particularly epilepsies with a genetic etiology.Selected Publications
Asadollahi R, Ahmad A, Boonsawat P, Shahanoor Hinzen J, Lohse M, Bouazza-Arostegui B, Sun S, Utesch T, Sommer JD, Ilic D, Padmanarayana M, Fischermanns K, Ranjan M, Boll M, Ka C, Piton A, Mattioli F, Isidor B, Õunap K, Reinson K, Wojcik MH, Marshall CR, Mercimek-Andrews S, Matsumoto N, Miyake N, Stephan BO, Honjo RS, Bertola DR, Kim CA, Yusupov R, Mefford HC, Christodoulou J, Lee J, Heath O, Brown NJ, Baker N, Stark Z, Delatycki M, Lake NJ, Zeidler S, Zuurbier L, Maas SM, de Kruiff CC, Rajabi F, Rodan LH, Coury SA, Platzer K, Oppermann H, Abou Jamra R, Beblo S, Maxton C, Śmigiel R, Underhill H, Dubbs H, Rosen A, Helbig KL, Helbig I, Ruggiero SM, Fitzgerald MP, Kraemer D, Prada CE, Tenney J, Jayakar P, Redon S, Lefranc J, Uguen K, Race S, Efthymiou S, Maroofian R, Houlden H, Coppens S, Deconinck N, Ashokkumar B, Varalakshmi P, Gowda K VR, Eghbal F, Ghayoor Karimiani E, Heidari M, Neidhardt J, Owczarek-Lipska M, Korenke GC, Bamshad MJ, Campeau PM, Lehman A, Hendon LG, Wentzensen IM, Monaghan KG, Chen Y, Szuto A, Cohn RD, Au PYB, Hübner C, Boschann F, Manickam K, Koboldt DC, Rad A, Oprea G, Bachman KK, Seeley AH, Agolini E, Terracciano A, Carmelo P, Bupp C, Grysko B, Rein-Rothschild A, Ben Zeev B, Margolin A, Morrison J, Dagli A, Stolerman E, Louie RJ, Washington C, Stevens SJC, Heijligers M, Alkuraya FS, Lisfeld J, Neu A, Paoli Monteiro F, Santos Pessoa AL, Camelo-Filho AE, Kok F, Koeberl D, Riley K, Burglen L, Doummar D, Héron B, Mignot C, Keren B, Charles P, Nava C, Bernhard FP, Kühn AA, Thoms S, Morrie RD, Mekhoubad S, Green EM, Barmada SJ, Gitler AD, Jahn O, Rhee JS, Rosenmund C, Mitkovski M, Sticht H, Sun H, Le Gac G, Taschenberger H, Brose N, Dittman JS, Rauch A, Lipstein N.: Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function. Nat Genet. Page: doi: 10.1038/s41588-025-02361-5, Oct 2025.Dekker J, Schot R, Aldinger KA, Everman DB, Washington C, Jones JR, Sullivan JA, Spillmann RC, Shashi V, Vitobello A, Denommé-Pichon AS, Mosca-Boidron AL, Perrin L, Auvin S, Zaki MS, Gleeson JG, Meave N, Wallace C, Nambot S, Delanne J, Ruggiero SM, Helbig I, Fitzgerald MP, Leventer RJ, Grange DK, Argilli E, Sherr EH, Prakash S, Neilson DE, Nicita F, Sferra A, Bertini ES, Aiello C, Brockmann K, Kuranov AB, Kaulfuss S, Basit S, Alluqmani M, Almatrafi A, Friedman JM, Guimond C, Mohammed F, Sharma P, Goel D, Wirth T, Anheim M, Bahena P, Koparir A, Kolokotronis K, Vona B, Haaf T, Kunstmann E, Maroofian R, Sczakiel HL, Boschann F, Misra-Isrie M, Louie RJ, Stolerman ES, Sanchez-Lara PA, Mergler S, Oegema R, Zarate YA, Kariminejad A, Tajsharghi H, Zeidler S, Kievit AJA, Bouman A, Cappuccio G, Brunetti-Pierri N, Stuurman KE, Swols DM, Tekin M, Upadia J, Martin DM, Craven D, Hiatt SM, van de Pol LA, D'Arco F, Margot H, Wilke M, Yousefi S, Barakat TS, van Veghel-Plandsoen MM, Aronica E, Anink J, Rogers SL, Slep KC, Doherty D, Dobyns WB, Mancini GMS.: A clinical and genotype-phenotype analysis of MACF1 variants. Am J Hum Genet. 112(10): 2363-2380, Oct 2025.
Sarah Woodson, William D. James, Rudolf Roth, John S. Barbieri, Sherry Ershadi, Debby Cheng, and Mark P. Fitzgerald: Mosaic Ring 20 Syndrome: A Meta Analysis. Neurology: Genetics 16(11(4)): e200282. doi: 10.1212/NXG.0000000000200282, August 2025.
The SCN8A Research Consortium. : A research roadmap for SCN8A-related disorders: addressing knowledge gaps and aligning research priorities across stakeholders. Orphanet J Rare Dis 20(444): https://doi.org/10.1186/s13023-025-03672-w, August 2025.
Laura Jolitz Ingo Helbig, Mark P Fitzgerald, Sarah McKeown Ruggiero, Stacey Cohen, Chloe Angelini, Elena Vallespin, Vincent Michaud, Anna Gerasimenko, Benjamin Cogne, Bertrand Isidor, Boris Keren, David Dyment, Delphine Heron, Helena Gásdal Karstensen, Inge Cuppen, John Christodoulou, Meredith Wilson, Nicole J Lake, Saskia Biskup, Steffen Syrbe, Takayasu Mori, Lena-Luise Becker, Angela M Kaindl: Phenotype Spectrum of TRPM3-Associated Disorders. Ann Neurol 97(3): 561-570, Mar 2025.
Jolitz L, Helbig I, Fitzgerald MP, McKeown Ruggiero S, Cohen S, Angelini C, Vallespin E, Michaud V, Gerasimenko A, Cogne B, Isidor B, Keren B, Dyment D, Heron D, Karstensen HG, Cuppen I, Christodoulou J, Wilson M, Lake NJ, Biskup S, Syrbe S, Mori T, Becker LL, Kaindl AM: Phenotype Spectrum of TRPM3-Associated Disorders. Ann Neurol. 97(3): 561-570, March 2025.
Shavonne L. Massey; Amanda G. Sandoval Karamian; Mark P. Fitzgerald; France W. Fung; Abigail Abramson; Mandy K. Salmon; Darshana Parikh; Nicholas S. Abend: Development of a model to predict electroencephalographic seizures in neonates with hypoxic ischemic encephalopathy treated with therapeutic hypothermia. Epilepsia 66(2): 518-530, Feb 2025.
Gabrielle Conecker, Maya Y Xia, JayEtta Hecker, Christelle Achkar, Cristine Cukiert, Seth Devries, Elizabeth Donner, Mark Fitzgerald, Elena Gardella, Michael Hammer, Anaita Hegde, Chunhui Hu, Mitsuhiro Kato, Tian Luo, John M. Schreiber, Yi Wang, Tammy Kooistra, Madeleine Oudin, Kayla Waldrop, J. Tyler Youngquist, Dennis Zhang, Elaine Wirrell, M. Scott Perry: Global modified Delphi consensus on diagnosis, phenotypes, and treatment of SCN8A-related epilepsy and/or neurodevelopmental disorders. Epilepsia Page: https://doi.org/10.1111/epi.17992, May 2024.
Gabrielle Conecker, Maya Y Xia, JayEtta Hecker, Christelle Achkar, Cristine Cukiert, Seth Devries, Elizabeth Donner, Mark Fitzgerald, Elena Gardella, Michael Hammer, Anaita Hegde, Chunhui Hu, Mitsuhiro Kato, Tian Luo, John M. Schreiber, Yi Wang, Tammy Kooistra, Madeleine Oudin, Kayla Waldrop, J. Tyler Youngquist, Dennis Zhang, Elaine Wirrell, M. Scott Perry: Global Modified-Delphi Consensus on Comorbidities and Prognosis of SCN8A-Related Epilepsy and/or Neurodevelopmental Disorders. Epilepsia Page: https://doi.org/10.1111/epi.17992, May 2024.
France W Fung, Darshana S Parikh, Kathleen Walsh, Mark P Fitzgerald, Shavonne L Massey, Alexis A Topjian, Nicholas S Abend: Late-Onset Findings During Extended EEG Monitoring Are Rare in Critically Ill Children. J Clin Neurophysiol Page: doi: 10.1097/WNP.0000000000001083, April 2024.