faculty photo

Delia Maria Talos, MD

Research Assistant Professor of Neurology
Department: Neurology

Contact information
University of Pennsylvania
Perelman School of Medicine
263 Clinical Research Building
415 Curie Boulevard
Philadelphia, PA 19104
Office: 215-573-8328
Fax: 215-662-3362
Education:
MD (Medicine)
University of Cologne, Germany, 1992.
Post-Graduate Training
Resident in Surgery, Clinic for Surgery and Reconstructive Surgery, Aachen, Germany, 1994-1996.
Research Fellow in Neurophysiology, University of Muenster, Germany, 1998-2000.
Research Fellow in Neurology and Neuroscience, Boston Children's Hospital, Boston, MA, 2001-2006.
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Description of Research Expertise

basic mechanisms of epilepsy, epilepsy biomarkers, neuroinflammation, epilepsy pre-clinical trials

Selected Publications

Puneet Bagga, Damodara Reddy, Delia Talos, Kimberly Sansalone, Leah Jacobs, Gaurav Verma, Hari Hariharan, Ravinder Reddy: Imaging the effect of high protein diet on the brain Glutaryl-CoA dehydrogenase deficient mice using GluCEST MRI. International Society for Magnetic Resonance in Medicine, Paris/ France 2018 Notes: Poster.

Sarah Gourmaud, Kimberly Sansalone, David J. Irwin, Delia M. Talos and Frances E. Jensen: Excitation: inhibition imbalance associates with increased pathology in Alzheimer's disease. Society for Neuroscience, San Diego, CA. Neuroscience Meeting Planner. Program No. 738.10. Online. 2018 Notes: Poster.

Alejandro Salah, Delia Talos, Kimberly Sansalone, Pelin Dilsiz, Werner Doyle, Howard Weiner, Richard W. Tsien, Orrin Devinsky : IL-1beta is proconvulsive and dependent of the Src pathway in human brain slices from refractory epilepsy patients. American Epilepsy Society Meeting, New Orleans, LA. Abstract Viewer Abst. 2018 Notes: Poster.

Kimberly Sansalone, Pelin Dilsiz, Howard L. Weiner, Orrin Devinsky, Delia M. Talos: Neoangiogenesis and Blood-Brain Barrier Dysfunction in Human TSC Brain Lesions American Epilepsy Society Meeting, New Orleans, LA. Abstract Viewer Abst. 3.075 2018 Notes: Poster.

Karbi L. Choudhury, Kimberly Sansalone, Frances E Jensen, Delia M. Talos: Potential loss of astrocyte synaptogenic function in human TSC cortical tubers American Epilepsy Society Meeting, New Orleans, LA. Abstract Viewer Abst. 2018 Notes: Poster.

Sarah Gourmaud, Delia M. Talos, Frances E. Jensen: Stress-activated pathways may contribute to Alzheimer’s disease (AD)-like pathology in human drug-resistant epilepsy. American Epilepsy Society Meeting, New Orleans, LA. Abstract Viewer Abst. 2018 Notes: Poster.

Talos, DM, Jacobs LM, Gourmaud, S, Coto, CA, Sun, H, Lim, KC, Lucas TH, Davis, KA, Martinez-Lage, M, Jensen, FE: Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy. Ann Neurol 83(2): 311-327, 2018.

Jacobs L, Gourmaud S, Dichter M, Kolson D, Jensen FE, Talos DM. : Perturbed regulation of redox signaling and inflammation in human therapy-resistant epilepsy: new opportunities for therapeutic interventions. American Epilepsy Society Meeting, Washington, DC. Abstract Viewer Abst. 2.059 2017 Notes: Poster.

Gourmaud S, Talos D, Jacobs L, Handy M, Vassar RJ, Jensen FE. : Interactions between epilepsy and Alzheimer's disease: novel therapeutic strategies. Society for Neuroscience, Washington, DC. Neuroscience Meeting Planner. Program No. 358.08. Online. 2017 Notes: Nanosymposium “Synaptic Signaling Deficits in Alzheimer's Disease I”

Gourmaud S, Jacobs L, Talos DM, Jensen FE. : Dysregulation of the amyloid precursor protein processing in human drug-resistant epilepsy. American Epilepsy Society Meeting, Washington, DC. Abstract Viewer Abst. 3.046 2017 Notes: Poster.

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Last updated: 10/16/2018
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