Carlyn Patterson Gentile, MD, PhD
Assistant Professor of Neurology at the Children's Hospital of Philadelphia
Senior Fellow, Center for Injury Prevention and Recovery, Children's Hospital of Philadelphia
Director, Headache Fellowship, Children's Hospital of Philadelphia
Factuly, Clinical Futures, Children's Hospital of Philadelphia
Department: Neurology
Graduate Group Affiliations
Publications
Links
Search PubMed for articles
For a list of my peer-reviewed publications please see the following link.
Search PubMed for articles
For a list of my peer-reviewed publications please see the following link.
Education:
BA (Neuroscience)
Hamilton College, 2006.
PhD (Neuroscience)
Albert Einstein College of Medicine, 2012.
MD (Medicine)
Albert Einstein College of Medicine, 2014.
BA (Neuroscience)
Hamilton College, 2006.
PhD (Neuroscience)
Albert Einstein College of Medicine, 2012.
MD (Medicine)
Albert Einstein College of Medicine, 2014.
Post-Graduate Training
Intern, Pediatrics, Children's Hospital of Philadelphia, 2014-2015.
Resident, Pediatrics, Children's Hospital of Philadelphia, 2015-2016.
Resident, Child Neurology, Children's Hospital of Philadelphia and the University of Pennsylvania, 2016-2019.
Fellow, Headache, Children's Hospital of Philadelphia, 2019-2020.
Intern, Pediatrics, Children's Hospital of Philadelphia, 2014-2015.
Resident, Pediatrics, Children's Hospital of Philadelphia, 2015-2016.
Resident, Child Neurology, Children's Hospital of Philadelphia and the University of Pennsylvania, 2016-2019.
Fellow, Headache, Children's Hospital of Philadelphia, 2019-2020.
Certifications
American Board of Psychiatry and Neurology, Board Certification in Neurology with Special Qualification in Child Neurology, 2019.
United Council of Neurologic Subspecialties, Board Certification in Headache, 2020.
Permanent linkAmerican Board of Psychiatry and Neurology, Board Certification in Neurology with Special Qualification in Child Neurology, 2019.
United Council of Neurologic Subspecialties, Board Certification in Headache, 2020.
Description of Clinical Expertise
I have clinical expertise in child neurology and headache. I see a range of primary and secondary headache disorders with a particular focus on post-traumatic headache. I am certified in peripheral nerve block procedures for the acute treatment of headache, and onobotulinum toxin A chemodenervation for the treatment of chronic headache.Description of Research Expertise
I have research expertise in the following areas:1. Visual neuroscience including encoding of visual information in neural networks, modeling of neural networks, and visual signal processing using perceptual and electrophysiologic metrics.
2. Application of model-based fitting to analysis of symptom clusters in youth with headache.
3. Biomarker clinical research, particularly related to concussion and headache in pediatric populations.
4. Use of biosensors to continuously monitor real-world light exposure.
5. Computer software programing using Matlab and R coding languages.
Selected Publications
Patterson Gentile, C., Shah, R., Marquez de Prado, B., Raj, N., Szperka, C.L., Hershey, A.D., Aguirre, G.K.: Daily Light Exposure Habits of Youth with Migraine and the Association with Headache Frequency. American Academy of Neurology, Chicago, IL April 2026.Patterson Gentile, C., Grady, M.: In-Office Management of Concussion, Acute and Persistent Postconcussion Symptoms, Including Management of Posttraumatic Headache. Neurology Clinics 2026.
Patterson Gentile, C.: Should my Child Play Contact Sports? Headache: The Journal of Head and Face Pain 2026.
Sehgal, R., Szperka, C.L., Hershey, A.D., Patterson Gentile, C.: Patient reported trigger, not the speed of transition to continuous headache, is associated with headache-related disability in children: Results of a cross-sectional clinic-based study. Cephalalgia 2026.
Patterson Gentile, C., Aguirre, G.K., Hershey, A.D., Szperka, C.L.: Headache-associated photophobia is more prevalent during winter: a cross-sectional study from a pediatric headache registry. Headache: The Journal of Head and Face Pain 2026.
Patterson Gentile, C., Thomas, A., Shah, R., Marquez de Prado, B., Raj, N., Szperka, C.L., Aguirre, G.K.: Evaluating chest-worn light logger adherence: development and application of a wear/non-wear model. Scientific Reports 2026.
Abuhalaweh, N., Gelfand, A., Evans, M., Marquez de Prado, B., Patterson Gentile, C., Raj, N., Hershey, A.D., Szperka, C.L.: Treatment outcomes in new daily persistent headache in children and adolescents. Cephalalgia 46(6): 3331024261426562, 2026.
Jenkins, C., Vossough, A., Tucker, A., Patterson Gentile, C., Szperka, C.L.: “Defining Normative Physiologic Parameters of Cerebellar Tonsil Position in the Pediatric Population” American Headache Society, Scottsdale, AZ December 2025.
Patterson Gentile, C.: Should my child play contact sports? Vumedi Learning Platform December 2025.
Gentile, C. P., Shah, R., Marquez de Prado, B., Raj, N., Szperka, C. L., Hershey, A. D., & Aguirre, G. K.: Daily light exposure habits of youth with migraine: A prospective pilot study Biological Timing and Sleep November 2025.