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Carlyn Patterson Gentile, MD, PhD

Assistant Professor of Neurology at the Children's Hospital of Philadelphia
Center for Injury Prevention and Recovery Senior Fellow, Children's Hospital of Philadelphia and the University of Pennsylvania
Department: Neurology

Contact information
BA (Neuroscience)
Hamilton College, 2006.
PhD (Neuroscience)
Albert Einstein College of Medicine, 2012.
MD (Medicine)
Albert Einstein College of Medicine, 2014.
Post-Graduate Training
Intern, Pediatrics, Children's Hospital of Philadelphia, 2014-2015.
Resident, Pediatrics, Children's Hospital of Philadelphia, 2015-2016.
Resident, Child Neurology, Children's Hospital of Philadelphia and the University of Pennsylvania, 2016-2019.
Fellow, Headache, Children's Hospital of Philadelphia, 2019-2020.
American Board of Psychiatry and Neurology, Board Certification in Neurology with Special Qualification in Child Neurology, 2019.
United Council of Neurologic Subspecialties, Board Certification in Headache, 2020.
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Description of Clinical Expertise

I have clinical expertise in child neurology and headache. I see a range of primary and secondary headache disorders with a particular focus on post-traumatic headache. I am certified in peripheral nerve block procedures for the acute treatment of headache, and onobotulinum toxin A chemodenervation for the treatment of chronic headache.

Description of Research Expertise

I have research expertise in visual neuroscience including encoding of visual information in neural networks, modeling of neural networks, and visual signal processing using perceptual and electrophysiologic metrics. I have experience in computer software programing using Matlab coding language. I am developing expertise in clinical research, and specifically biomarker study design for clinical trial use, particularly related to concussion and headache in pediatric populations.

Selected Publications

Huber, C.M., Patton, D.A., Round, K.R., Patterson Gentile, C., Master, C.L., Arbogast, K.B.: Neurophysiological effects of repeated soccer heading in youth. ASME Journal of Biomedical Engineering 145, September 2023.

Patterson Gentile, C., Aguirre, G.K., Hershey, A.D. and Szperka, C.L.: Symptoms associated with headache in youth. Cephalalgia 43(7): 03331024231187162, 2023.

Patterson Gentile, C, Spitschan, M, Taskin, HO, Bock, AS, Aguirre, GK: Temporal sensitivity for achromatic and chromatic flicker across the visual cortex. BioRxIV 2023.

Murphy, C., Ladak, A., Marquez De Prado, B., Szperka, C.L., Hershey, A.S., Patterson Gentile, C.: Anxiety, depression and headache-related disability in a large pediatric cohort. American Headache Society 65th Annual Scientific Conference 2023.

Ladak, A., Murphy, C., Marquez De Prado, B., Szperka, C.L., Hershey, A., Patterson Gentile, C.: Characterization of youth with headaches who report neck pain. American Headache Society 65th Annual Scientific Conference 2023.

Patterson Gentile C, Aguirre GK, Hershey AD, Szperka CL.: Comparison of continuous headache features in youth with migraine, new daily persistent headache, and persistent post-traumatic headache. Cephalalgia 43(1), 2023.

Patterson Gentile, C.: Physical Activity Intervention in Youth with Concussion. Pediatrics 2023.

Carlyn Patterson Gentile, Geoffrey K. Aguirre, Andrew D. Hershey, Christina L. Szperka: A case-control study of continuous headache in youth with migraine, persistent post-traumatic headache, and new daily persistent headache. AHS Annual Scientific Conference, Denver, CO June 2022.

Patterson Gentile, C., Aguirre G.K., Arbogast K.B., Master, C.L.: The relationship between visually evoked effects and concussion in youth. Journal of Neurotrauma March 2022 Notes: accepted, publication pending.

Patterson Gentile, C, Aguirre, GK, Hershey, AD, Szperka, CL: Associated Symptom Clusters in Youth with Headache. Annals of Neurology, 147th Annual Meeting 2022.

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Last updated: 07/28/2023
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