faculty photo

Katheryn Alexandra Quilico Cousins-Gershenson, PhD

Research Assistant Professor of Neurology
Research Education Component (REC) Co-Leader, Penn Alzheimer’s Disease Research Center (ADRC)
Biomarker Core Co-Lead, Penn Alzheimer’s Disease Research Center (ADRC)
Department: Neurology

Contact information
Richards Medical Building, Suite 600B
3700 Hamilton Walk
Philadelphia, PA 19104
Graduate Group Affiliations
Education:
BA ( Biological Sciences)
University of Chicago, 2007.
PhD (Neuroscience)
Brandeis University, 2015.
Post-Graduate Training
Postdoctoral Fellow in Neurology, University of Pennsylvania, 2014-2018.
Postdoctoral Research in Neuroscience, Washington University, 2018-2019.
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Description of Research Expertise

Biofluid markers of neuropathology

Selected Publications

Cousins KAQ, Korecka M, Wan Y, Vulaj A, Brown C, Tropea TF, Lee EB, Tosun D, Landau SM, Okonkwo OC, Mindt MR, Weiner MW, Irwin DJ, Wolk DA, Shaw LM; and the Alzheimer's Disease Neuroimaging Initiative.: Comparison of plasma p-tau217/Aβ42, p-tau217, and Aβ42/Aβ40 biomarkers by race to detect Alzheimer's disease. Alzheimers Dement Aug 2025.

Stirland LE, Choate R, Zanwar PP, Zhang P, Watermeyer TJ, Valletta M, Torso M, Tamburin S, Saeed U, Ridgway GR, Moukaled S, Lusk JB, Loi SM, Littlejohns TJ, Kuźma E, James SN, Grande G, Foote IF, Cousins KAQ, Butler J, AbuHamdia A, Avelino-Silva TJ, Suryadevara V.: Multimorbidity in dementia: Current perspectives and future challenges. Alzheimers Dement 21(8), Aug 2025.

Brown CA, Mundada NS, Cousins KAQ, Sadeghpour N, Lyu X, McGrew E, Korecka M, Chen-Plotkin A, Xie L, Wisse LEM, Detre JA, McMillan CT, Lee EB, Nasrallah IM, Das SR, Mechanic-Hamilton D, Yushkevich PA, Shaw LM; Alzheimer’s Disease Neuroimaging Initiative; Wolk DA.: Tau-Clinical Mismatch Identifies Individuals with Co-Pathology and Predicts Clinical Trajectory. medRxiv Jul 2025.

Kim BJ, Aleman TS, Cousins KAQ, Daniel E, Smith E, Iacobucci E, Kolomeyer A, Hwang CK, McMillan CT, Van Deerlin VM, Phillips JS, Yu Y, Ying GS, Irwin DJ.: Choroidal evaluation of FTLD-Tau and biomarker-determined Alzheimer's disease. Sci Rep 15: 22290, Jul 2025.

Brown CA, Das SR, Cousins KAQ, Tropea TF, Plotkin AC, Detre JA, Yushkevich PA, McMillan CT, Lee EB, Shaw LM, Nasrallah IM; Alzheimer's Disease Neuroimaging Initiative; Wolk DA.: Tau burden is best captured by magnitude and extent: Tau-MaX as a measure of global tau. Alzheimers Dement 21(7), Jul 2025.

Stites SD, Kuz C, Halberstadter K, Humphreys V, Cousins KAQ, Mechanic-Hamilton D.: Societal gender norms and their influence on Late Life Cognition. Neurodegener Dis Jun 2025.

Zhao AT, Nair RM, Lee EB, Cousins KAQ, Irwin DJ, Kim BJ.: Retinal imaging and tissue analysis for frontotemporal degeneration: recent advances and challenges for biomarker development. J Neurol Neurosurg Psychiatry Jun 2025.

Boyle, Xu, Cousins, Dehghani, Morse, Verma, Shaw, Massimo, Zhou, Wolk, McMillan, & the Penn Medicine Biobank: Epigenetic age acceleration is faster in Black adults and is associated with plasma amyloid (Invited talk) Penn Population Aging Research Center Aging Retreat – Limits of Chronological Age May 2025.

Boyle R, Dehghani N, Emrani S, Wadhwani AR, Matyi M, Cousins KAQ, Rhodes E, Nelson B, Stites SD, Xie SX, Dratch L, Van Deerlin VM, Snyder A, Irwin D, McMillan CT, Massimo L.: Neighborhood deprivation moderates prognosis in behavioral-variant frontotemporal degeneration. medRxiv May 2025.

Kac, Cousins, Shaw, Karikari, Turton, van Deerlin, Harrison, McMillan, Kvartsberg, Zetterberg, Wolk, Lee, Irwin, & Blennow: MTBR-Tau368 improves diagnostic accuracy for FTLD-TAU from FTLD-TDP. International Conference on Alzheimer’s and Parkinson’s Diseases and Related Neurological Disorders (AD/PD), Vienna, Austria April 2025.

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Last updated: 08/16/2025
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