Dennis J. Dlugos, MD, MSCE
Professor of Neurology at the Children's Hospital of Philadelphia
Director, Pediatric Epilepsy Program, Division of Neurology, The Children's Hospital of Philadelphia
Associate Dean for UME Science and Discovery Curriculum, Perelman School of Medicine at the University of Pennsylvania
Department: Neurology
Contact information
Division of Neurology
Children's Hospital of Philadelphia
34th Street and Civic Center Blvd
The Hub for Clinical Collaboration
10th floor, Room 10537
Philadelphia, PA 19104
Children's Hospital of Philadelphia
34th Street and Civic Center Blvd
The Hub for Clinical Collaboration
10th floor, Room 10537
Philadelphia, PA 19104
Office: 215-590-1719
Email:
dlugos@email.chop.edu
dlugos@email.chop.edu
Education:
B.A. (Theology)
Loyola Marymount University, Los Angeles, CA, 1983.
M.D. (Medicine)
Columbia University College of Physicians & Surgeons, New York, NY, 1988.
M.S.C.E (Clinical Epidemiology)
Master’s of Science in Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, 2002.
B.A. (Theology)
Loyola Marymount University, Los Angeles, CA, 1983.
M.D. (Medicine)
Columbia University College of Physicians & Surgeons, New York, NY, 1988.
M.S.C.E (Clinical Epidemiology)
Master’s of Science in Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, 2002.
Post-Graduate Training
Intern in Pediatrics, National Naval Medical Center, Bethesda, MD, 1988-1989.
Resident in Pediatrics, Thomas Jefferson University & Alfred I. Dupont Institute, Philadelphia, PA & Wilmington, DE, 1993-1994.
Resident in Neurology/Child Neurology, University of Pennsylvania Medical Center & The Children’s Hospital of Philadelphia, Philadelphia , 1994-1997.
Fellow in Epilepsy and Clinical Neurophysiology, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1997-1999.
Intern in Pediatrics, National Naval Medical Center, Bethesda, MD, 1988-1989.
Resident in Pediatrics, Thomas Jefferson University & Alfred I. Dupont Institute, Philadelphia, PA & Wilmington, DE, 1993-1994.
Resident in Neurology/Child Neurology, University of Pennsylvania Medical Center & The Children’s Hospital of Philadelphia, Philadelphia , 1994-1997.
Fellow in Epilepsy and Clinical Neurophysiology, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1997-1999.
Certifications
Pediatrics (1998 - 2012), American Board of Pediatrics, 1998.
Neurology with Special Qualifications in Child Neurology, American Board of Psychiatry and Neurology, 1998.
Clinical Neurophysiology (1999-2009), American Board of Psychiatry and Neurology, 1999.
Clinical Neurophysiology with Special Qualifications in Epilepsy Monitoring, American Board of Clinical Neurophysiology, 1999.
Epilepsy, American Board of Psychiatry and Neurology, 2013.
Permanent linkPediatrics (1998 - 2012), American Board of Pediatrics, 1998.
Neurology with Special Qualifications in Child Neurology, American Board of Psychiatry and Neurology, 1998.
Clinical Neurophysiology (1999-2009), American Board of Psychiatry and Neurology, 1999.
Clinical Neurophysiology with Special Qualifications in Epilepsy Monitoring, American Board of Clinical Neurophysiology, 1999.
Epilepsy, American Board of Psychiatry and Neurology, 2013.
Description of Research Expertise
Epilepsy EpidemiologyEpilepsy Genetics
Clinical Prediction Models
Description of Clinical Expertise
Pediatric EpilepsyEpilepsy Genetics
Epilepsy Surgery
EEG
Clinical Neurophysiology
Selected Publications
Ferrer M, Jandhyala N, Pellinen J, Greenwood H, Thio LL, Dlugos D, Park KL, Kanner AM, French J, for Human Epilepsy Project Investigators : Delayed Diagnosis in Adolescent-Onset Focal Epilepsy: Impact on Morbidity and Mental Health. Epilepsia doi.org/10.1111/epi.18434, 2025.Shah D, Villanueva V, Dlugos J, Benitez A, Taylor Y, Olsen S, Connolly H, Lai S, Andrews JS : Non-Seizure Symptoms and Broader Seizure Impacts in Patients with Dravet Syndrome and Lennox-Gastaut Syndrome in Clinical Practice Settings: Results From a Multi-National Survey. Epilepsia Open in press, 2025.
Dlugos D, Lozano M, DiVentura B, Farfel G, Shellhaas RA, Sullivan JE, Thio LL, Kessler SK, Sadleir L, French J: Appropriate selection of participants in pediatric developmental and epileptic encephalopathy trials: Lessons learned and future opportunities. Epilepsia 66: e121-e126, 2025.
Omurtag A, Abdulbaki S, Thesen T, Waechter R, Landon B, Evans R, Dlugos D, Chari G, LaBeaud AD, Hassan YI, Fernandes M, Blackmon K: Disruption of functional network development in children with prenatal Zika virus exposure revealed by resting-state EEG. Scientific Reports 15: 6346, 2025.
Alkofer M, Yang C, Ganglberger W, Beal J, Hegde M, Kang JY, Yoo JY, Gelfand MA, Thio LL, Kutluay E, Campbell Z, Schmitt S, Gleichgerrcht E, Waterhouse E, Lopez MR, Eisenschenk S, Galanti M, Singh RK, Wills KE, Meulenbrugge EJ, Dlugos D, Dean B, Halford J, Goldenholz D, Jing J, Thomas R, Westover MB: Automated detection of interictal epileptiform discharges with few electroencephalographic channels. Epilepsia 66: e114-e120, 2025.
Greenwood H, Ferrer M, Jandhyala N, Dlugos D, Park K, Thio L, Pellinen J, Kanner A, French J: Prevalence of Suicidality in Adolescents with Newly Diagnosed Focal Epilepsy at Diagnosis and over the Following 36 Months. Neurology 103: e209397, 2024.
Epi4K Consortium (including Dlugos DJ): The role of copy number variants in the genetic architecture of common familial epilepsies. Epilepsia 65: 792-804, 2024.
Perry MS, Scheffer IE, Sullivan J, Brunklaus A, Boronat S, Wheless J, Laux L, Patel AD, Roberts CM, Dlugos D, Holder D, Knupp KG, Lallas1 M, Phillips S, Segal E, Smeyers P, Lal1 D, Wirrell E, Zuberi S, Brünger T, Wojnaroski M, Maru B, O’Donnell P, Morton M, James E, Vila C, Huang N, Gofshteyn JS, Rico S: Severe Communication Delays Are Independent of Seizure Burden and Persist Despite Contemporary Treatments in SCN1A+ Dravet Syndrome: Insights from the ENVISION Natural History Study. Epilepsia 65: 322-337, 2024.
Bozorg A, Beller C, Jensen L, Arzimanoglou A, Chiron C, Dlugos D, Gaitanis J, Wheless J, McClung C: Pitfalls of Using Video-EEG for a Trial Endpoint in Children Aged <4 Years with Focal Seizures. Annals of Clinical and Translational Neurology Page: 10.1002/acn3.51999, 2024.
Jandhyala N, Ferrer Socorro M, Greenwood H, Pellinen J, Dlugos D, Park K, Thio L, French J: Unrecognized Focal Non-Motor Seizures in Adolescents Presenting to Emergency Departments. Neurology 102: e209389, 2024.