Jillian McKee, MD, PhD
Instructor A of Neurology
Instructor of Neurology, University of Pennsylvania
Department: Neurology
Contact information
The HUB Center for Clinical Collaboration
Children's Hospital of Philadelphia
3500 Civic Center Blvd
Philadelphia, PA 19104
Children's Hospital of Philadelphia
3500 Civic Center Blvd
Philadelphia, PA 19104
Education:
BSc (Honours Physiology)
McGill University, 2007.
PhD (Computational Neuroscience)
University of Chicago, 2014.
MD (Medicine)
University of Chicago, 2016.
BSc (Honours Physiology)
McGill University, 2007.
PhD (Computational Neuroscience)
University of Chicago, 2014.
MD (Medicine)
University of Chicago, 2016.
Post-Graduate Training
Pediatrics Resident, Children's Hospital of Philadelphia, 2016-2018.
Neurology Resident, Children's Hospital of Philadelphia, 2018-2021.
Epilepsy Genetics Fellow, Children's Hospital of Philadelphia, 2021-2022.
Pediatric Epilepsy Fellowship, Children's Hospital of Philadelphia, 2022-2023.
Health Services Research Academy, Tier 1 Participant, Children’s Hospital Association, 2022-2022.
Pediatrics Resident, Children's Hospital of Philadelphia, 2016-2018.
Neurology Resident, Children's Hospital of Philadelphia, 2018-2021.
Epilepsy Genetics Fellow, Children's Hospital of Philadelphia, 2021-2022.
Pediatric Epilepsy Fellowship, Children's Hospital of Philadelphia, 2022-2023.
Health Services Research Academy, Tier 1 Participant, Children’s Hospital Association, 2022-2022.
Certifications
American Board of Psychiatry and Neurology, 2021.
American Board of Psychiatry & Neurology - Pediatric Epilepsy, 2024.
Permanent linkAmerican Board of Psychiatry and Neurology, 2021.
American Board of Psychiatry & Neurology - Pediatric Epilepsy, 2024.
Selected Publications
McKee JL, Magielski J, Xian J, Cohen S, Toib J, Harrison A, Chen C, Kim D, Rathod A, Brimble E, Fitter N, Graglia JM, Helde KA, Ruggiero SM, Boland MJ, Prosser BL, Sederman R, Helbig I.: Clinical signatures of SYNGAP1-related disorders through data integration. Genetics in Medicine 27(6), June 2025 Notes: https://doi.org/10.1016/j.gim.2025.101419.Mondragon E, Magielski JH, Bane B, Nolan J, Ruggiero SM, Armstrong D, Arnold S, Sirsi D, Helbig I, McKee JL.: Clinical trajectories and medication response in TBC1D24-related epilepsies. Epilepsia (under review) June 2025.
Magielski J, Cohen S, Kaufman M, Parthasarathy S, Xian J, Brimble E, Fitter N, Furia F, Gardella E, Moller R, Helbig I, and McKee JL.: Deciphering the Natural History of SCN8A-Related Disorders. Neurology 104(9), May 2025.
Harrison AG, Magielski JH, McSalley I, Ganesan S, Prentice AJ, Cunningham KG, Pierce SR, Boland MJ, Prosser BL, Helbig I, McKee JL.: Familial SYNGAP1 variants define the boundaries of a complex neurodevelopmental disorder with epilepsy. Epilepsia May 2025.
Magielski J, Cohen S, Kaufman M, Parthasarathy S, Xian J, Brimble E, Fitter N, Furia F, Gardella E, Moller R, Helbig I, and McKee JL. : Deciphering the dynamic clinical patterns in SCN8A-related disorders using real-world data. medRxiv (accepted to Neurology) March 2025.
Magielski J, Ruggiero SM, Xian J, Parthasarathy S, Galer P, Ganesan S, Back A, McKee J, McSalley I, Gonzalez AK, Morgan A, Donaher J, Helbig I.: The clinical and genetic spectrum of paediatric speech and language disorders in 52,143 individuals. Brain February 2025.
Ganesan S, Ruggiero SM, Parthasarathy S, Galer PD, Lewis-Smith D, McSalley I, Cohen SR, Lusk L, Prentice AJ, McKee JL, Pendziwiat M, Smith L, Weber Y, Mefford HC, Poduri A, Helbig I.: Phenotypic analysis of 11,125 trio exomes in neurodevelopmental disorders. bioRxiv (submitted to Nature Neuroscience) 2025 Notes: doi: https://doi.org/10.1101/2025.03.11.642649.
Galer PD, McKee JL, Ruggiero SM, Kaufman MC, McSalley I, Ganesan S, Ojemann WKS, Gonzalez AK, Cao Q, Litt B, Helbig I, Conrad EC.: Quantitative EEG Spectral Features Differentiate Genetic Epilepsies and Predict Neurologic Outcomes. medrxiv (accepted to Neurology) 2025 Notes: https://doi.org/10.1101/2024.10.09.24315105.
Pierce S, Cunningham K, Coyne J, Decampo D, Demarest S, Graglia M, Goss J, Harrison A, Helde K, McKee JL, Son Rigby C, Sullivan K, Tefft S, Chao HT, Grinspan Z, Miele A, Boland M, Ruggerio S, Helbig I: STXBP1 and SYNGAP1 Related Disorders: Assessing the Feasibility of Developmental Outcome Measures. AES, Los Angeles, CA December 2024 Notes: poster.
Galer P, McKee JL, Ruggerio S, Kaufman M, Mcsalley I, Ganesan S, Ojemann W, Pattnaik A, Gonzalez A, Litt B, Helbig I, Conrad E: Genetic Epilepsies Demonstrate Distinct Electrographic Signatures in STXBP1, SCN1A, and SYNGAP1. AES, Los Angeles, CA December 2024 Notes: poster.