Selected Publications

Brown CA, Mundada NS, Cousins KAQ, Sadeghpour N, Lyu X, McGrew E, Korecka M, Chen-Plotkin A, Xie L, Wisse LEM, Detre JA, McMillan CT, Lee EB, Nasrallah IM, Das SR, Mechanic-Hamilton D, Yushkevich PA, Shaw LM, Wolk DA; Alzheimer’s Disease Neuroimaging Initiative.: Evaluation of Copathology and Clinical Trajectories in Individuals With Tau-Clinical Mismatch. JAMA Neurol 83: 126-136, Feb 2026.

Lyu X, Mundada NS, Brown CA, Sadeghpour N, McGrew E, Xie L, Li Y, Wuestefeld A, Duong MT, Cook P, Gee J, Nasrallah IM, Chen-Plotkin AS, Shaw LM, Mechanic-Hamilton D, Wisse LEM, Yushkevich PA, Das SR, Wolk DA, for the Alzheimer’s Disease Neuroimaging Initiative: Medial temporal lobe Tau-Neurodegeneration mismatch from MRI and plasma biomarkers. Brain 2026 Notes: in press.

Brown CA, Cousins KAQ, Korecka M, McGrew E, Chen-Plotkin A, Detre JA, McMillan CT, Lee EB, Das SR, Mechanic-Hamilton D, Yushkevich PA, Nasrallah IM, Shaw LM, Alzheimer’s Disease Neuroimaging Initiative, Wolk DA: Temporal Modeling of Amyloid and Tau Trajectories in Alzheimer’s Disease using PET and Plasma Biomarkers. Ann Neurol 2026 Notes: in press.

Brown CA, Das SR, Detre JA, Nasrallah IM, Yushkevich PA, McMillan CT, Wolk DA.: Fully individualized models for cross-sectional and longitudinal network-based tau spread. Imaging Neurosci (Camb) 3: IMAG, Dec 2025.

Mundada NS, Lyu X, Brown CA, Sadeghpour N, McGrew E, Xie L, Cook PA, Gee J, Yushkevich PA, Das SR, Wolk DA; Alzheimer's Disease Neuroimaging Initiative.: Enrichment of patients with concomitant limbic-predominant age-related TDP-43 encephalopathy (LATE) on the Alzheimer's disease continuum using hippocampal volume. Alzheimers Dement 21(12): e70970, Dec 2025.

Shakibajahromi B, Dolui S, Brown CA, Taghvaei M, Sadaghiani S, Khandelwal P, Das S, Yushkevich PA, Nasrallah IM, Xie SX, Wolk DA, Detre JA.: Clinical correlates of perfusion and diffusion MRI metrics in cognitively unimpaired older adults. J Cereb Blood Flow Metab Dec 2025 Notes: doi: 10.1177/0271678X251389043. Online ahead of print.

Li Y, Xie L, Khandelwal P, Wisse LEM, Brown CA, Prabhakaran K, Tisdall MD, Mechanic-Hamilton D, Detre JA, Das SR, Wolk DA, Yushkevich PA.: Automatic Segmentation of Medial Temporal Lobe Subregions in Multi-Scanner, Multi-Modality Magnetic Resonance Imaging of Variable Quality. Hippocampus 35(6): e70036, Nov 2025.

Sreepada LP, Brown CA, Das SR, Yushkevich PA, Wolk DA, McMillan CT: Biological age acceleration in Alzheimer's disease modulates relative cortical to medial temporal lobe neurodegeneration Neurobiol Aging 153: 21-29, Sep 2025.

Cousins KAQ, Boyle R, Morse C, Verma A, Brown CA, O'Brien KS, Serper M, Dehghani N; Penn Medicine BioBank; McMillan CT, Lee EB, Shaw LM, Wolk DA.: Electronic Health Records to Test Multimorbidity Influences to Plasma Biomarker Interpretation for Alzheimer's Disease. Ann Neurol Aug 2025 Notes: doi: 10.1101/2025.08.16.25333799. Online ahead of print.

Cousins KAQ, Korecka M, Wan Y, Vulaj A, Brown C, Tropea TF, Lee EB, Tosun D, Landau SM, Okonkwo OC, Mindt MR, Weiner MW, Irwin DJ, Wolk DA, Shaw LM: Comparison of plasma p-tau217/Aβ42, p-tau217, and Aβ42/Aβ40 biomarkers by race to detect Alzheimer's disease Alzheimers Dement 21(8): e70469, Aug 2025.