University of Pennsylvania Health System

Department of Ophthalmology

Ophthalmology Faculty

Faculty Overview

Albert M. Maguire, MD

faculty photo
F.M. Kirby Professor of Molecular Ophthalmology
Co-Director, Fellowship Program, Vitreoretinal Surgery, University of Pennsylvania
Co-Director, Center for Retinal and Ocular Therapeutics (CAROT), University of Pennsylvania Perelman School of Medicine
Department: Ophthalmology

Contact information
Scheie Eye Institute
Department of Ophthalmology
University of Pennsylvania
51 North 39th Street
Philadelphia, PA 19104
Education:
B.A.
Princeton University (magna cum laude), 1982.
M.D.
Harvard University, 1986.
Post-Graduate Training
Intern in Surgery, Yale-New Haven Hospital, Department of Surgery, Yale University School of Medicine, New Haven, CT, 1986-1987.
Resident in Ophthalmology, The Wilmer Ophthalmological Institute, The Johns Hopkins Hospital, Baltimore, MD, 1987-1990.
Fellowship, Associated Retinal Consultants, William Beaumont Hospital, Royal Oak, MI, 1990-1991.
Certifications
American Board of Ophthalmology, 1991.
SOCA Eligible and Certified Personnel, 2002.
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Description of Research Expertise

Gene therapy for retinal degeneration, gene therapy for ocular neovascularization, Subretinal surgery; Animal models; Recombinant Adeno-Associated Virus (AAV); Retinal Function and Functional Vision Outcome Measures

Description of Clinical Expertise

diabetic retinopathy, retinopathy of prematurity, macular degeneration, sickle cell disease, gene therapy, retinal degeneration; von Hippel-Lindau Syndrome

Selected Publications

Pierce, EA, Aleman, TS, Jayasundera, KT, Ashimaley, BS, Kim, E, Rashid, A, Jaskolka, MC, Myers, RL, Lam, BL, Bailey, ST, Comander, JI, Lauer, AK, Maguire, AM and Pennesi, ME: Gene Editing for CEP290-Associated Retinal Degeneration. New England Journal of Medicine Page: Published online May 6, 2024, May 2024 Notes: DOI: 10.1056/NEJMoa2309915.

Tsui, JC, Huang, V, Kolmeyer, AM, Miller, CG, Mishkin, A and Maguire, AM: Efficacy of maribavir in valganciclovir-resistant cytomegalovirus retinitis. Retina Cases Brief Rep 18(2): 164-167, March 2024 Notes: DOI: 10.1097/ICB.0000000000001372.

Tsui JC, Wong, MB, Kim, BJ, Maguire, AM, Scoles, D, VanderBeek, BL, Brucker, AJ : Appropriateness of ophthalmic symptoms triage by a popular online artificial intelligence chatbot. Eye (Lond) 37(17): 692-3693, December 2023 Notes: Doi: 10.1038/s41433-023-02556-2.

Ashtari, M, Cook, P, Lipin, M, Yu, Y, Ying, G-S, Maguire, AM, Bennett, J, Gee, J, Zhang, H: Dynamic structural remodeling of the human visual system prompted by bilateral retinal gene therapy. Current Research in Neurobiology 4: online 4 June 2023, June 2023 Notes: https://doi.org/10.1016/j.crneur.2023.100089.

Bennett, J and Maguire, AM: Lessons Learned from the Development of the First FDA-Approved Gene Therapy Drug, Voretigene Neparvovec-rzyl; Cold Spring Harb Perspect Med 13: a041307, May 2023 Notes: https://pubmed.ncbi.nlm.nih.gov/36167727/

Tsui, JC, Wong, MB, Kim, BJ, Maguire, AM, Scoles, D, VanderBeek, BL, Brucker, AJ: Appropriateness of ophthalmic symptoms triage by a popular online artifician intelligence chatbot. Eye (Lond) 32(e24), Apr 2023.

Silson, EH, Baker, CI, Aleman, TS, Maguire, AM, Bennett, J and Ashtari, M: Motion-selective areas V5/MT and MST appear resistant to deterioration in choroideremia. Neuroimage Clin 38: 103384, March 2023 Notes: doi:10.1016/j.nicl.2023.103384.

Andersen, T, Miller, CG, Xia, T, Pulido, JS, Brucker, AJ, Maguire, AM: Vitreoretinal lymphoma presenting as frosted branch angiitis in a patient with diffuse large B-cell lymphoma. Am J Ophthalmol Case Rep 30: 101838, Mar 2023.

Andersen T, Miller CG, Xia T, Pulido JS, Brucker AJ, Maguire AM: Vitreoretinal lymphoma presenting as frosted branch angiitis in a patient with diffuse large B-cell lymphoma. Am J Ophthalmol Case Rep 30: 101838, March 2023 Notes: doi: 10.1016/j.ajoc.2023.101838.

Bennett, J, Aleman, EMM, Maguire, HK, Weber, ML, Maguire, WM, Maja, A, O'Neil, EC, Maguire, AM, Miller, AJ and Aleman, TS: Optimization and validation of a virtual reality orientation and ombility test for inherited retinal degenerations. Transl Vis Sci Technol 12(1): 28, Jan 2023.

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Last updated: 05/12/2024
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