University of Pennsylvania Health System

Department of Ophthalmology

Ophthalmology Faculty

Faculty Overview

Gui-shuang Ying, MD, PhD

faculty photo
Associate Professor of Ophthalmology at the Hospital of the University of Pennsylvania
Department: Ophthalmology

Contact information
3535 Market Street, Suite 700
Philadelphia, PA 19104
Graduate Group Affiliations
MD (Preventive Medicine)
Zhejiang Medical University, 1993.
MPH (Toxicology)
Zhejiang Medical University, 1996.
MS (Biostatistics)
University of Michigan-Ann Arbor, 2000.
PhD (Biostatistics)
University of Pennsylvania, 2004.
Post-Graduate Training
Research Assistant, Zhejiang Medical University, Department of Toxicology, 1993-1996.
Research Assistant, University of Michigan, Department of Environmental Health Sciences, School of Public Health, 1993-1993.
Research Assistant, University of Illinois at Chicago, Department of Disability and Human Development, 1996-1998.
Teacher Assistant, University of Michigan, Department of Biostatistics, School of Public Health, 1998-1998.
Biostatistician Internship, Department of Biostatistics, STATPROBE, Inc., 1999-1999.
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Description of Research Expertise

Dr. Ying is an Associate Professor of Ophthalmology, Associate Scholar in Biostatistics, and Director of the Biostatistical Consulting Service in the Center for Preventive Ophthalmology and Biostatistics. Dr. Ying received his MD from P.R. China and Ph.D. in Biostatistics from University of Pennsylvania in 2004. Dr. Ying is the Principal Investigator or the Director of the Data Coordinating Center for several NIH-funded studies on retinopathy of prematurity (ROP), age-related macular degeneration, and the co-investigator or senior biostatistician for several NIH-funded multi-center clinical trials or observational studies. Dr. Ying collaborates with investigators for the study design, data management, statistical analysis, data interpretation and manuscript writing for the multi-center clinical studies. Dr. Ying has extensive experience in proving biostatistical consulting service to the biomedical investigators, mostly in vision and ophthalmology community. Dr. Ying’s statistical methodologic research interest is the development of risk prediction models for eye diseases and statistical analysis for correlated data. Dr. Ying has authored and co-authored 230+ papers in peer-reviewer journals.

Key words
Biostatistics consulting, prediction model, correlated data analysis

Description of Other Expertise

Biostatistical consulting, prediction in clinical trials, risk prediction models for eye diseases, statistical analysis of clustered data, statistics in diagnostic testing

Selected Publications

Ying GS, Dobson V, Quinn G, Maguire M, Kulp MT, Cyert L and Vision in Preschoolers (VIP) Study Group.: Impact of Confidence Number on the Accuracy of SureSight Vision Screener. Optom Vis Sci 87: 96-103, 2010.

Simonelli F, Maguire AM, Testa F ,Pierce EA, Mingozzi F, Bennicelli J, Rossi S, Marshall K, Banfi S, Surace EM, Sun J, Redmond M, Zhu X, Shindler KS, Ying GS, Ziviello C, Acerra C, Wright JF, DcDonnel JW, High KA, Bennett J, Auricchio A.: Gene therapy for Leber’s congenital amaurosis is safe and effective through 1.5 years after vector administration. Molecular Therapy 18: 643-50, 2010.

Maguire AM, High KA, Auriccho A, Wright JF, Pierce EA, Testa F, Mingozzi F, Bennicelli J, Ying GS, Rossi S, Marshall KA, Banfi S, Chung D, Morgan JA, Hauck B, Zelanaia O, Zhu X, Raffini L, Coppieters F, Elfride DB, Schindler K, Volpe N, Surace EM, Acerra C, Lyubarsky A, Redmond TM, Stone E, Sun J, , McDonnell JW, Leroy BP, Simonelli F, Bennett J.: Phase I gene therapy shows reversal of congenital blindness: Age-dependent effect of treatment. Lancet 374: 1597-605, 2009.

Ying GS, Maguire MG, Alexander J, Martin R, Antoszyk A: Description of the AREDS 9-step severity scale applied to participants in CAPT. Archives of Ophthalmology 127: 1147-51, 2009.

Maguire MG, Ying GS, McCannel C, Liu CC. Dai Y.: Statin use and the incidence of advanced age-related macular degeneration in the Complications of Age-related Macular Degeneration Prevention Trial (CAPT). Ophthalmology 116: 2381-5, 2009.

Ying GS, Maguire MG, Liu C, Antoszyk AN, and the CAPT Research Group: Night Vision Symptoms and Progression of Age-Related Macular Degeneration in the Complications of Age-related macular degeneration Prevention Trial. Ophthalmology 115(11): 1876-1882, 2008.

Ying GS, Heitjan DF: Weibull Prediction of Event Times in Randomized Clinical Trials. Pharmaceutical Statistics 7: 107-120, 2008.

Ying GS, Heitjan DF, Chen T. Nonparametric prediction of event times in randomized clinical trials. Clinical Trials 2004; 1:352-61: Nonparametric prediction of event times in randomized clinical trials. Clinical Trials 1: 352-61, 2004.

Schenk M, Schwartz AG, O’Neal E, Kinnard M, Greenson JK, Fryzek JP, Ying GS, Garabrant DH: Familial risk of pancreas cancer. J Natl Cancer Inst 93: 640-4, 2001.

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Last updated: 08/29/2018
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