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Norbert Pardi, PhD

Assistant Professor of Microbiology
Vaccines Group Lead, Penn Institute for RNA Innovation, Perelman School of Medicine, University of Pennsylvania
Department: Microbiology

Contact information
476A Stemmler Hall
Philadelphia, PA 19104
Office: 215 746 6552
Graduate Group Affiliations
Education:
MSc (Biochemistry and Genetics)
University of Szeged, Hungary, 2004.
PhD (Biochemistry and Genetics)
University of Szeged, Hungary, 2011.
Post-Graduate Training
Research Fellow, Young Investigator Research Fellowship of the Hungarian Academy of Sciences, 2007-2011.
Fellow in mRNA-based vaccine development, University of Pennsylvania, 2011-2016.
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Description of Research Expertise

mRNA therapeutics

Selected Publications

Hogan MJ, Maheshwari N, Begg BE, Nicastri A, Hedgepeth EJ, Muramatsu H, Pardi N, Miller MA, Reilly SP, Brossay L, Lynch KW, Ternette N, Eisenlohr LC: Cryptic MHC-E epitope from influenza elicits a potent cytolytic T cell response. Nat Immunol. 11(24): 1933-1946, Nov 2023.

Zhang L, More KR, Ojha A, Jackson CB, Quinlan BD, Li H, He W, Farzan M, Pardi N, Choe H.: Effect of mRNA-LNP components of two globally-marketed COVID-19 vaccines on efficacy and stability. NPJ Vaccines 1(8): 156, Oct 2023.

Pine M, Arora G, Hart TM, Bettini E, Gaudette BT, Muramatsu H, Tombácz I, Kambayashi T, Tam YK, Brisson D, Allman D, Locci M, Weissman D, Fikrig E, Pardi N.* *corresponding author: Development of an mRNA-lipid nanoparticle vaccine against Lyme disease. Mol Ther 9(31): 2702-2714, Sep 2023.

Chung C, Kudchodkar SB, Chung CN, Park YK, Xu Z, Pardi N, Abdel-Mohsen M, Muthumani K.: Expanding the Reach of Monoclonal Antibodies: A Review of Synthetic Nucleic Acid Delivery in Immunotherapy. Antibodies (Basel) 3(12): 46, Jul 2023.

Matias J, Cui Y, Tang X, Sajid A, Arora G, Wu MJ, DePonte K, Muramatsu H, Tam YK, Narasimhan S, Pardi N, Weissman D, Fikrig E: Specific mRNA lipid nanoparticles and acquired resistance to ticks. Vaccine 34(41): 4996-5002, Jul 2023.

Deak C, Pardi N, Miklosi A: The fire of research: Katalin Kariko's legacy. Biol Futur. 74(1-2), Jun 2023.

Deak C, Pardi N, Miklosi A: Innovation in the 21st century: following the footsteps of Katalin Kariko. Biol Futur 74(1-2): 101-108, Jun 2023.

Cable J, Graham BS, Koup RA, Seder RA, Karikó K, Pardi N, Barouch DH, Sharma B, Rauch S, Nachbagauer R, Forsell MNE, Schotsaert M, Ellebedy AH, Loré K, Irvine DJ, Pilkington E, Tahtinen S, Thompson EA, Feraoun Y, King NP, Saunders K, Alter G, Moin SM, Sliepen K, Karlsson Hedestam GB, Wardemann H, Pulendran B, Doria-Rose NA, He WT, Juno JA, Ataca S, Wheatley AK, McLellan JS, Walker LM, Lederhofer J, Lindesmith LC, Wille H, Hotez PJ, Bekker LG.: Progress in vaccine development for infectious diseases-a Keystone Symposia report. Ann N Y Acad Sci 1(154): 65-86, Jun 2023.

Cesaro A, Lin S, Pardi N, de la Fuente-Nunez C: Advanced delivery systems for peptide antibiotics. Adv Drug Deliv Rev(196), 114733, May 2023.

Amanat F, Clark J, Carreno JM, Strohmeier S, Yellin T, Meade PS, Bhavsar D, Muramatsu H, Sun W, Coughlan L, Pardi N, Krammer F: Immunity to Seasonal Coronavirus Spike Proteins Does Not Protect from SARS-CoV-2 Challenge in a Mouse Model but Has No Detrimental Effect on Protection Mediated by COVID-19 mRNA Vaccination. J Virol. online, 3(97): e0166422, Mar 2023.

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Last updated: 12/01/2023
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