faculty photo

Charles E. Leonard, PharmD, MSCE, FISPE

Associate Professor of Epidemiology in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Department: Biostatistics and Epidemiology

Contact information
Perelman School of Medicine at the University of Pennsylvania
807 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Office: 215-573-2663
Fax: 215-573-5315
Lab: 215-573-2663
Education:
PharmD (Clinical Pharmacy)
Duquesne University, 2001.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2011.
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Selected Publications

Dhopeshwarkar N, Yang W, Hennessy S, Rhodes JM, Cuker A, Leonard CE: SuperLearner with high-dimensional propensity score to improve confounding adjustment: A real-world application in chronic lymphocytic leukemia. Pharmacoepidemiol Drug Saf 33(1): e5678, Jan 2024.

Dhopeshwarkar N, Yang W, Hennessy S, Rhodes JM, Cuker A, Leonard CE.: Bleeding with concomitant ibrutinib and oral anticoagulant therapy: A population-based cohort study. Am J Hematol 98(3): E49-E52, Mar 2023.

Chen C, Hennessy S, Brensinger CM, Bilker WB, Dublin S, Chung S, Horn J, Bogar K, Leonard CE: Antidepressant drug-drug-drug interactions associated with unintentional traumatic injury: Screening for signals in real-world data. Clin Transl Sci 16(2): 326-337, Feb 2023.

Bogar K, Brensinger CM, Hennessy S, Flory JH, Bell ML, Shi C, Bilker WB, Leonard CE.: Climate change and ambient temperature extremes: Association with serious hypoglycemia, diabetic ketoacidosis, and sudden cardiac arrest/ventricular arrhythmia in persons with type 2 diabetes. Diabetes Care 45(11): e171-e173, Nov 2022.

Dawwas GK, Hennessy S, Brensinger CM, Acton EK, Bilker WB, Chung S, Dublin S, Horn JR, Manis MM, Miano TA, Oslin DW, Pham Nguyen TP, Soprano SE, Wiebe DJ, Leonard CE.: Signals of Muscle Relaxant Drug Interactions Associated with Unintentional Traumatic Injury: A Population-Based Screening Study. CNS Drugs 36(4): 389-400, Apr 2022.

Medaglio D, Stephens-Shields AJ, Leonard CE.: Research and scholarly methods: Propensity scores. J Am Coll Clin Pharm 5(4): 467-475, Apr 2022.

Dawwas GK, Leonard CE, Lewis JD, Cuker A.: Risk for Recurrent Venous Thromboembolism and Bleeding With Apixaban Compared With Rivaroxaban: An Analysis of Real-World Data. Ann Intern Med 175(1): 20-28, Jan 2022.

Dawwas GK, Flory JH, Hennessy S, Leonard CE, Lewis JD.: Comparative Safety of Sodium-Glucose Cotransporter 2 Inhibitors Versus Dipeptidyl Peptidase 4 Inhibitors and Sulfonylureas on the Risk of Diabetic Ketoacidosis. Diabetes Care 45(4): 919-927, Apr 2022.

Dawwas GK, Dietrich E, Cuker A, Barnes GD, Leonard CE, Lewis JD.: Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial Fibrillation : A Population-Based Cohort Study. Ann Intern Med 174(4): 910-919, Jul 2021.

Leonard CE, Flory JH, Likić R, Ogunleye OO, Wei L, Wong I.: Spotlight commentary: A role for real-world evidence to inform the clinical care of patients with diabetes mellitus. Br J Clin Pharmacol 87(12): 4549-4551, Dec 2021.

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Last updated: 07/05/2024
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