Laboratory for Individualized Breast Radiodensity Assessment

The Laboratory for Individualized Breast Radiodensity Assessment (LIBRA), a software package developed by the Computational Breast Imaging Group (CBIG) at the University of Pennsylvania, is a fully-automatic breast density estimation software solution based on a published algorithm that works on either raw (i.e., “FOR PROCESSING”) or vendor post-processed (i.e., “FOR PRESENTATION”) digital mammography images from two vendors: GE Healthcare and Hologic. Based on an algorithm published in Medical Physics, LIBRA has been applied to over 30,000 screening exams and is being increasingly utilized in larger studies.

LIBRA has two modes of operations:

  1. An easy-to-use interactive mode with Graphical-User-Interface where the user is prompted to select either a single DICOM image or a folder of DICOM images, an output folder for the results, and whether they wish to save intermediate files.
  2. A command-line interface amenable to batch processing and scripting, where the user can explicitly define the input and output paths.