1 |
Jean Richa |
Transgenic and Chimeric Mouse Facility |
Jean Richa, Kathleen Moosbrugger, Peifu He, and Douglas Epstein |
Core/Resource Translational Research |
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2 |
Heather Collins |
RIA Biomarker Core |
Dr Michael Rickels, Director; Dr Heather Collins, Technical Director; Brenda Spurgeon, Xiaolan Li |
Core/Resource Translational Research |
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3 |
Jonathan Schug |
Next-Generation Sequencing Core / Functional Genomics Core |
Jonathan Schug, Olga Smirnova, Kyia Rutherford, Klaus Kaestner |
Core/Resource Translational Research |
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4 |
Nicolai Doliba |
Pancreatic Islet Cell Biology Core |
D. A. Stoffers, Director, F. M. Matschinsky, Co-Director, N. M. Doliba, Technical Director, A. V. Rozo, Assistant Technical Director |
Core/Resource Translational Research |
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5 |
Wenyun Lu |
Metabolomics Core |
Wenyun Lu, Joshua D. Rabinowitz |
Core/Resource |
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6 |
Katherine Yerkes |
The Human Metabolic Tissue Resource |
Katerine Yerkes, Raymond Soccio |
Core/Resource Translational Research |
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7 |
John Millar |
IDOM Metabolic Tracer Resource |
Huong-Lan Nguyen, John Millar |
Core/Resource Translational Research |
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8 |
Amy Peleckis |
IDOM Human Metabolism Resource |
Amy Peleckis, Cornelia Dalton-Bakes, Eileen Markmann, Kathryn Gallagher, Huong-Lan Nguyen, Anneliese Flatt, Michael R. Rickels |
Core/Resource Translational Research |
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9 |
Giulia Maurizi |
A physiological role of brain inflammation is to augment counter regulation to prevent hypoglycemia |
Giulia Maurizi1, Kenichi Sakamoto1,2, Claudia Liberini1, Chunxue Zhou1, Jessica Hu1, Bandy Chen1,2, Alice Butera1,2, Dirk Homann1, Christoph Buettner1,2. |
Complications |
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10 |
Xin Sheng |
Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments |
Xin Sheng#, Yuting Guan#, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu, Zhen Miao, Matthew J. Seasock, Matthew Palmer, Myung K. Shin, Kevin L. Duffin, Steven S. Pullen, Todd L. Edwards, Jacklyn N. Hellwege, Adriana M. Hung, Mingyao Li, Benjamin F. Voight, Thomas Coffman, Christopher D. Brown, Katalin Susztak |
Complications |
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11 |
Kun Zhu |
Rhythmic Transcription Regulated by REV-ERBa Condensates in the 3D Genome |
Kun Zhu, Dongyin Guan, Yang Xiao, Wenxiang Hu, Pieterjan Dierickx, Chunjie Jiang, Marine Adlanmerini, Mitchell Lazar |
Complications |
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12 |
Anna Garcia Whitlock |
Loss of FOXO Transcription Factors in the Liver Improves Stress-Induced Hyperglycemia |
Anna E. Garcia Whitlock MD, Jaimarie Sostre Colón BS, Matthew Gavin BA, Niels D. Martin MD, Joseph A. Baur PhD, Carrie A. Sims MD PhD, Paul M. Titchenell PhD |
Complications |
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13 |
Tomoya Sakamoto |
The Nuclear Receptor ERR Cooperates with the Cardiogenic Factor GATA4 to Orchestrate Transcriptional Control of Cardiac Maturation |
Tomoya Sakamoto, Shibiao Wan, Kirill Batmanov, and Daniel P. Kelly |
Complications |
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14 |
Karthikeyani Chellappa |
Fueling Microbial NAD Metabolism |
Karthikeyani Chellappa, Melanie R McReynolds, Timothy Cox, Lev Litichevskiy, Xianfeng Zeng, Yashaswini R Bhat, Siddharth R Lingala, Lixin Ji, Wenyun Lu, Christoph Thaiss, Joshua D Rabinowitz, Joseph A Baur |
Obesity |
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15 |
Jeff Ishibashi |
Large-insert CRISPR gene targeting in mice using in-house purified long ssDNA. |
Jeff Ishibashi, David Merrick, Patrick Seale |
Obesity |
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16 |
Aaron McKnight |
Dissociating the peripheral pathways utilized by glucose and fat to communicate with hypothalamic hunger neurons |
Aaron D. McKnight, Nitsan Goldstein, Jamie R.E Carty, J. Nicholas Betley, Amber L. Alhadeff |
Obesity |
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17 |
Amy Hauck |
Defining the molecular mechanisms of HDAC3 action in vivo |
Amy K. Hauck, Bryce Carpenter, Hannah Richter, Mitchell A. Lazar |
Obesity |
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18 |
Boa Kim |
Altered Lipid Droplet Metabolism in the endothelium links the metabolic syndrome to hypertension |
Boa Kim, Soon Y Tang, Ayon Ibrahim, Jian Li, Garret A FitzGerald, Zoltan Arany |
Obesity |
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19 |
Lauren Woodie |
The vagus nerve regulates circadian gene expression in the liver. |
Lauren N. Woodie, Brianna M. Krusen, Kirill Batmanov, Dongyin Guan, Caroline Geisler, Matthew Hayes, Mitchell A. Lazar |
Obesity |
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20 |
Hannah Richter |
Novel functions for nuclear receptor corepressors in thermogenic adipose tissue |
Hannah J Richter, Amy K Hauck, B Nahri So, Matthew J Emmett, Mindy Kim, Mitchell A Lazar |
Obesity |
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21 |
Delaine Zayas-Bazan |
Circadian REV-ERBalpha Interactome in the Liver |
Delaine M. Zayas-Bazan, Marine Adlanmerini, Amy K. Hauck, Brianna M. Krusen, Mitchell A. Lazar |
Obesity |
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22 |
Tomohito Doke |
Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis. |
Tomohito Doke, Shizheng Huang, Chengxiang Qiu, Hongbo Liu, Yuting Guan, Hailong Hu, Ziyuan Ma, Junnan Wu, Zhen Miao, Xin Sheng, Jianfu Zhou, Aili Cao, Jianhua Li, Lewis Kaufman, Adriana Hung, Christopher D Brown, Richard Pestell and Katalin Susztak. |
Translational Research |
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23 |
Yehuda Shabtai |
Thyroid Hormone Action in Liver: A Coregulator Shift Rather Than the Canonical Switch |
Yehuda Shabtai, Nagaswaroop K. Nagaraj, Kirill Batmanov, Young-Wook Cho, Yuxia Guan, Chunjie Jiang, Jarrett Remsberg, Douglas Forrest and Mitchell A. Lazar |
Translational Research |
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24 |
Stephanie Hanke |
PFOA Exposure Prior to Hepatocyte Differentiation Leads to Gene Expression Changes Implicated in Non-Alcoholic Fatty Liver Disease |
Stephanie Hanke, MD, MS, Apoorva Joshi, MS, Weixuan Fu, MS, Paul Z. Wang, PhD, Pheruza Tarapore, PhD, Rebecca A. Simmons, MD, Sara E. Pinney, MD, MS |
Translational Research |
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25 |
Lucien Turner |
The NAD Salvage Pathway is a Novel Regulator of T Cell Activation |
Lucien Turner, Clemence Queriault, Janet Nguyen, James Davis, Patrick Schaefer, Michael Scaglione, Kelly Rome, Brian Goldspiel, Alice Sukhina, Joseph Baur, Will Bailis |
Translational Research |
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26 |
Pieterjan Dierickx |
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function |
Pieterjan Dierickx, Kun Zhu, Chunjie Jiang, Yang Xiao, Timothy S. Luongo, Bryce J. Carpenter, Marit W. Vermunt, Sobuj Mia, Mary Latimer, Abhinav Diwan, Juanjuan Zhao, Amy K. Hauck, Brianna Krusen, Hoang C.B. Nguyen, Gerd A. Blobel, Daniel P. Kelly, Liming Pei, Joseph A. Baur, Martin E. Young, Mitchell A. Lazar |
Translational Research |
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27 |
Amin Abedini |
CUrinary single cell profiling captures the cellular diversity of the kidney |
Amin Abedini, Yuan O. Zhu, Shatakshee Chatterjee, Gabor Halasz, Kishor Devalaraja-Narashimha, Rojesh Shrestha, Michael Balzer, Jihwan Park, Tong Zhou, Ziyuan Ma, Katie Marie Sullivan, Hailong Hu, Xin Sheng, Hongbo Liu, Yi Wei, Carine M Boustany-Kari, Uptal Patel, Salem Almaani, Matthew Palmer, Raymond Townsend, Shira Blady, Jonathan Hogan, and The TRIDENT Study Investigators, Lori Morton and Katalin Susztak |
Translational Research |
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28 |
Katie Sullivan |
Glutathione Specific Gamma-Glutamylcyclotransferase 1 (CHAC-1) is a Chronic Kidney Disease Risk Gene |
Sullivan KM, Guan Y, Gu X, Sheng X, Susztak K |
Translational Research |
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29 |
Michael S. Balzer |
Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets |
Balzer MS, Miao Z, Ma Z, Liu H, Wu J, Shrestha R, Aranyi T, Kwan A, Kondo A, Pontoglio M, Kim J, Li M, Kaestner KH, Susztak K |
Translational Research |
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30 |
Junnan Wu |
African American-specific APOL1 risk variants in endothelial cells exacerbate sepsis and COVID19 severity |
Junnan Wu, Ziyuan Ma, Archana Raman, Pazit Beckerman, Matthew Palmer, Hua Chang Chen, Cassiane Robinson Cohen, Thomas Dunn, John Reilly, Nuala Meyer, Michael Shahaty, Zoltan Arany, György Haskó, Krzysztof Laudanski, Adriana Hung, Katalin Susztak |
Translational Research |
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31 |
Poonam Dhillon |
The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation |
Poonam Dhillon, Jihwan Park, Carmen Hurtado del Pozo, Tomohito Doke, Shizheng Huang, Juanjuan Zhao, Hyun Mi Kang, Rojesh Shrestra, Patricia Prado, Seung Yub Han, Hongbo Liu, Xin Sheng, Pieterjan Dierickx, Kirill Batmanov, Mingyao Li, Liming |
Translational Research |
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32 |
Joshua Benjet |
A Zebrafish Model of Hyperinsulinism |
Christine Juliana, Joshua Benjet, Christoph Seiler, and Diva D. De Leon |
Translational Research |
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33 |
Hailong Hu |
METTL10 is a kidney disease risk gene by altering protein methylation |
Hailong Hu, Katalin Susztak |
Translational Research |
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34 |
Christine Juliana |
Evaluation of the capacity of ion channels, Kv7.1 and TMEM16A, to modulate insulin secretion in pancreatic islets |
Christine A. Juliana, Pan Chen, Jinghua Chai, Toshinori Hoshi, Diva D. De León |
Translational Research |
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35 |
Kara Boodhansingh |
High frequency dominant KATP channel mutations in children with hypoglycemia: Is Congenital Hyperinsulinism more common than we thought? |
Kara E. Boodhansingh, Lauren Mitteer, Stacey Kleinman, Amanda Ackermann, Diva D. DeLeon, Arupa Ganguly, Charles A. Stanley |
Translational Research |
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36 |
Elizabeth Rosenfeld |
Characterizing the Brain Phenotype in Hyperinsulinism Hyperammonemia Syndrome Utilizing a Novel Neuroimaging Technique |
Elizabeth Rosenfeld, Ravi P.R. Nanga, Alfredo Lucas, Andy Revell, Ravinder Reddy, Kathryn A. Davis, Diva D. De Leon-Crutchlow |
Translational Research |
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37 |
Anneliese Flatt |
Evaluation of Clinical Metrics for Identifying Defective Physiologic Responses to Hypoglycemia in Long-standing Type 1 Diabetes |
Anneliese J.S. Flatt, Elizabeth Chen, Amy J. Peleckis, Cornelia Dalton-Bakes, Huong-Lan Nguyen, Michael R. Rickels |
Type 1 Diabetes |
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38 |
Matthew Haemmerle |
RNA binding proteins PCBP1 and PCBP2 promote postnatal β cell survival |
Matthew Haemmerle, Kirill Batmanov, Andrea Scota, Austin Good, Caroline Philpott, Stephen Liebhaber, Louis Ghanem, Doris Stoffers |
Type 1 Diabetes |
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39 |
Xiaodun Yang |
PDX1 directs a core developmentally and evolutionarily conserved gene program in the pancreatic islet |
Xiaodun Yang1,2*, Jeffrey C. Raum1,2*, Junil Kim3, Reynold Yu1, Juxiang Yang4, Gabriella Rice5, Changhong Li4, Kyoung-Jae Won3, Doris A. Stoffers1,2& and Diana E. Stanescu4,6& |
Type 1 Diabetes |
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40 |
Natasha Jaiswal |
Differential Role of Skeletal Muscle AKT Signaling in the Regulation of Glucose Metabolism and Muscle Growth |
Natasha Jaiswal, Matthew Gavin, William Quinn , Emanuele Loro, Rebecca Gefler, Joseph Baur, Tejvir S. Khurana and Paul M. Titchenell |
Type 2 Diabetes |
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41 |
Meghan Craven |
Endocrine Manifestations of Pediatric HNFB-MODY (MODY 5) |
Meghan E. Craven, Vaneeta Bamba, Andrew C. Calabria, and Sara E. Pinney |
Type 2 Diabetes |
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42 |
Patrick Van Hoose |
Phosphoglucomutase 1 deficiency induces hypoglycemia due to lower threshold for glucose-stimulated insulin secretion |
Patrick M. Van Hoose, Changhong Li, Miao He, Eva Morava, Hudson H. Freeze, Can Ficicioglu, Franz M. Matschinsky, Klaus H. Kaestner, Charles A. Stanley, Amanda M. Ackermann |
Type 2 Diabetes |
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43 |
Dominic Santoleri |
A new role for hepatic glucokinase and its regulatory protein in the direct regulation of cholesterol gene transcription and synthesis |
Dominic Santoleri, Matthew Gavin, Hee Woong Lim, Ben Garcia, David Merrick, David Steger, Paul Titchenell |
Type 2 Diabetes |
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44 |
Kahealani Uehara |
Activation of Hepatic mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De novo Lipogenesis |
Kahealani Uehara, Jaimarie Sostre, Anna E. Garcia Whitlock, Matthew Gavin, Paul M. Titchenell |
Type 2 Diabetes |
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45 |
Jaimarie Sostre-Colón |
Hepatic AKT regulates adipose tissue thermogenesis via catecholamine-induced lipolysis and circulating FGF21 |
Jaimarie Sostre-Colón, Kahealani Uehara, Anna E. Garcia Whitlock, Matthew J. Gavin, Jeff Ishibashi, Matthew J. Potthoff, Patrick Seale and Paul M. Titchenell |
Type 2 Diabetes |
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46 |
Varun Bahl |
Genetic activation of α-cell glucokinase in mice causes enhanced glucose-suppression of glucagon secretion during normal and diabetic states |
Varun Bahl, Catherine Lee May, Alanis Perez, Benjamin Glaser, and Klaus Kaestner |
Type 2 Diabetes |
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47 |
Long Gao |
Mapping effector genes at Type II Diabetic loci for human pancreatic alpha cells |
Long Gao, Chun Su, Matthew E. Johnson, Catherine L. May, Andrew D. Wells, Struan F. A. Grant, Klaus H. Kaestner |
Type 2 Diabetes |
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