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Welcome to the Kim Innovation Laboratory for Image-Guided Interventions. At the “KIMNOVATION” lab we are at the forefront of cerebrovascular research, conducting investigations into a diverse range of disorders affecting both intracranial and extracranial vessels, including brain aneurysms, congenital malformations, and strokes.

The heart of our lab is a state-of-the-art neurointerventional facility, led by Dr. Visish Srinivasan, committed to translational research in cerebrovascular diseases. Established in 2022 through the generous support of the Kim Family, KIMNOVATION is located on the 7th floor of the Smilow Center for Translational Research at the University of Pennsylvania's Perelman School of Medicine.

Members of Visish Srinivasan, MD's Kim Innovation Lab. — Lab team (left to right): Sandeep Kandregula, MD; Oleg Shekhtman, MD; Visish Srinivasan, MD; Sai Mannam, BS and Michael Cowell, BS

The lab, comprising 700 sq. ft. of wet lab space along with an animal prep area, facilitates a wide spectrum of experiments, covering both microsurgical and interventional radiology techniques. It is fully equipped with endovascular and microsurgical tools.

Currently, the lab boasts a cutting-edge operative suite featuring a Siemens high-definition mobile C-arm, a Siemens Sequoia ultrasound, a Mindray WATO anesthesia machine, and a Leica oeprating microscope. Additionally, a new Siemens ARTIS Pheno imaging system is scheduled for installation later this year as part of the upcoming renovation. The Pheno system offers robotic movements, advanced non-circular orbits, HD fluoroscopy, and advanced angiographic cone beam CT imaging capabilities. All imaging data collected during experiments is securely stored on the web-based FlyWheel platform, a proprietary neuroimaging informatics platform, providing encrypted cloud-based storage.

KIMNOVATION shares space with the Penn Image-Guided Interventions (PIGI) Lab, a part of the Departments of Radiology and Cancer Biology led by Dr. Terence Gade.