Perelman School of Medicine at the University of Pennsylvania

Lipschutz Lab

Lipschutz Lab

Lipschutz Lab Publications

  • Choi S.Y., Fogelgren, B., Zuo, X., Huang, L., McKenna, S., Lingappa, V.R., Lipschutz, J.H. 2012. Exocyst Sec10 is Involved in Basolateral Protein Translation and Translocation in the Endoplasmic Reticulum. Nephron Experimental Nephrology. 2012;120:e134-140
  • Chung, D.C., Fogelgren, B., Park, K.M., Heidenberg, J., Zuo, X., Huang, L., Bennett, J., Lipschutz, J.H. 2011. Adeno-Associated Virus (AAV)-Mediated Gene Transfer to Renal Tubule Cells via a Retrograde Ureteral Approach. Nephron Extra. 1:217-223. PMID: 3290852.
  • Zuo, X., Fogelgren, B., Lipschutz, J.H. 2011. The Small GTPase Cdc42 is Essential for Primary Ciliogenesis In Renal Tubular Epithelial Cells. Journal of Biological Chemistry. 286(25):22469-22477. PMID: 3121392.
  • Fogelgren, B., Lin, S.Y., Zuo, X., Jaffe, K., Park, K.M., Reichert, R.J., Bell, P.D., Burdine, R.D., Lipschutz, J.H. 2011. The Exocyst Protein Sec10 Interacts with Polycystin-2 and Knockdown Causes PKD-Phenotypes. PLoS Genetics. 7(4):1-17 (e1001361). PMID: 3072367.
  • Blosser, C., Ayehu, G., Wu, S., LoMagro, R.M., Mallone, E., Brunelli, S.M., Itkin, M., Golden, M., McCombs, P., Lipschutz, J.H. 2010. High Rate of Fistula Placement in a Cohort of Dialysis Patients in a Single Payer System. Hemodialysis International. 14(4):393-397. PMID: 3082920.
  • Park, K.M, Fogelgren, B., Zuo, X., Kim, J., Chung, D.C., Lipschutz, J.H. 2010. Exocyst Sec10 Protects Epithelial Barrier Integrity and Enhances Recovery Following Oxidative Stress, by Activation of the MAPK Pathway. American Journal of Physiology, Renal Physiology. 298(3): F818-826. PMID: 20053792.
  • Zuo, X., Guo, W., Lipschutz, J.H. 2009. The Exocyst Protein Sec10 is Necessary for Primary Ciliogenesis and Cystogenesis In Vitro. Molecular Biology of the Cell. 20:2522-2529 (highlighted in "MBC Incytes"). PMID: 19297529.
  • Berman, E., Lipschutz, J.M., Bloom, R.D., Lipschutz, J.H. 2008. The Bioethics and Utility of Selling Kidneys for Renal Transplantation. Transplantation Proceedings. 40:1264-1270. PMID: 18589084.
  • Hellman, N.E., Spector, J., Robinson, J., Zuo, X., Saunier, S., Antignac, C., Tobias, J.W., Lipschutz, J.H. 2008. Matrix Metalloproteinase 13 (MMP13) and Tissue Inhibitor of Matrix Metalloproteinase 1 (TIMP1), Regulated by the MAPK Pathway, are Both Necessary for MDCK Tubulogenesis. Journal of Biological Chemistry. 283(7): 4272-4282. PMID: 18039671.
  • Liu, Z., Greco, A. J., Hellman, N. E., Spector, J., Robinson, J., Tang, O. T., Lipschutz, J. H. 2007. Intracellular Signaling via ERK/MAPK Completes the Pathway for Tubulogenic Fibronectin in MDCK Cells. Biochemical and Biophysical Research Communications. 353(3): 793-798. PMID: 17196167.
  • Huber, W.G., Dahman, M.H., Thomas, D., Lipschutz, J.H. 2007. Practical Advance in Obtaining an Emergency Airway via Cricothyroidotomy. Military Medicine. 172(5): 504-506. PMID: 17521098.
  • Christensen, M., Su, A.W., Snyder, R.W., Greco, A., Lipschutz, J.H., Madaio, M.P. 2006. Simvastatin Protection Against Acute Immune-Mediated Glomerulonephritis in Mice. Kidney International. 69(3): 457-463. PMID: 16407885.
  • Hellman, N.E., Greco, A.J., Rogers, K.K., Balkovetz, D.F., Lipschutz, J.H. 2005. Activated Extracellular Signal Regulated Kinases (ERKs) are Necessary and Sufficient to Initiate Tubulogenesis in Renal Tubular MDCK Strain I Cell Cysts. American Journal of Physiology, Renal Physiology. 289(4): F777-785. PMID: 15900019.
  • Lipschutz, J.H., Li, S., Arisco, A., Balkovetz, D.F. 2005. Extracellular-Signal-Regulated Kinases 1/2 Control Claudin-2 Expression in Madin-Darby Canine Kidney Strain I and II Cells. Journal of Biological Chemistry. 280(5): 3780-3788. PMID: 15569684.
  • Berman, E., Merz, J.F, Rudnick, M., Snyder, R.W., Rogers, K.K., Lee, J., Johnson, D., Mosenkis, A., Israni, A., Wolpe, P.R., Lipschutz, J.H. 2004. Religiosity in a Hemodialysis Population and Its Relationship to Satisfaction with Medical Care, Satisfaction with Life, and Adherence. American Journal of Kidney Diseases. 44(3): 488-497. PMCID: 15332222.
  • Snyder, R.W., Ruhe, J., Kobrin, S., Wasserstein, A., Nachamkin, I., Lipschutz, J.H. 2004. Asaia Bogorensis Peritonitis, Identified by 16S Ribosomal RNA Sequence Analysis in a Patient Receiving Peritoneal Dialysis. American Journal of Kidney Diseases. 44: E15-17. PMID: 15264206.
  • O'Brien, L.E., Tang, K., Kats, E.S., Schutz-Geschwender, A., Lipschutz, J.H., Mostov, K.E. 2004. ERK and MMPs Sequentially Regulate Distinct Stages of Epithelial Tubule Development. Developmental Cell. 7:21-32. PMID: 15239951.
  • Rogers, K.K., Wilson, P.D., Zhang, X., Guo, W., Burrow, C.R., Lipschutz, J.H. 2004. The Exocyst Localizes to the Primary Cilium in MDCK Cells. Biochemical and Biophysical Research Communications. 319: 138-143. PMID: 15158452.
  • Balkovetz, D.F., Gerrard, Jr., E.R., Shixiong, L., Johnson, D., Lee, J., Tobias, J.W., Rogers, K.K., Snyder, R.W., Lipschutz, J.H. 2004. Gene Expression Alterations During HGF-Induced Dedifferentiation of a Renal Tubular Epithelial Cell Line (MDCK) Using a Novel Canine DNA Microarray. American Journal of Physiology, Renal Physiology. 286 F702-F710. PMID: 14665430.
  • Lipschutz, J.H., Lingappa, V.R., Mostov, K.E. 2003. The Exocyst Affects Protein Synthesis by Acting on the Translocation Machinery of the Endoplasmic Reticulum. Journal of Biological Chemistry. 278 (23): 20954-20960 (highlighted in Nature Reviews Molecular and Cell Biology, 2003, 4: 344). PMID: 12665531.
  • Rogers, K.K., Jou, T., Guo, W., Lipschutz, J.H. 2003. The Rho Family of Small GTPases is Involved in Epithelial Cystogenesis and Tubulogenesis. Kidney International. 63: 1632-1644. PMID: 12675838.
  • Zhang, X., Bi, E., Novick, P., Du, L., Kozminski, K.G., Lipschutz, J.H., and Guo, W. 2001. Cdc42 Interacts with the Exocyst and Regulates Polarized Exocytosis. Journal of Biological Chemistry. 276: 46745-46750. PMID: 11595741.
  • Mangravite, L.M., Lipschutz, J.H., Mostov, K.E., Giacomini, K.M. 2001. Localization of GFP-Tagged Concentrative Nucleoside Transporters, SPNT1-GFP and CNT1-GFP, in Renal Polarized Epithelial Cells. American Journal of Physiology. 280: F879-885. PMID: 11292631.
  • Lipschutz, J.H., Guo, W., O'Brien, L.E., Nguyen, Y.H., Novick, P., Mostov, K.E. 2000. The Exocyst is Involved in Epithelial Cystogenesis and Tubulogenesis and Acts by Modulating Synthesis and Delivery of Basolateral Plasma Membrane and Secretory Proteins. Molecular Biology of the Cell. 11: 4259-4275. PMID: 11102522.
  • Lipschutz, J.H. 1999. To Clone or Not to Clone: A Jewish Perspective. Journal of Medical Ethics. 25: 105-107. PMID: 10226913.
  • Lipschutz, J.H., Tatematsu, M., Kusakabe, M., Fukami, H., Yamamoto, M., Cunha, G.R. 1999. Clonality of Urogenital Organs as Determined by Analysis of Chimeric Mice. Cells Tissues Organs. 165: 57-66. PMID: 10516418.
  • Lipschutz, J.H., Kissil, J.L. 1998. Expression of b-catenin and g-catenin in Epithelial Tumor Cell Lines and Characterization of a Unique Cell Line. Cancer Letters. 126: 33-41. PMID: 9563646.
  • Baskin, L.S., Sutherland, R.S., DiSandro, M.J., Hayward, S.W., Lipschutz, J.H., Cunha, G.R. 1997. The Effect of Testosterone on Androgen Receptors and Human Penile Growth. Journal of Urology. 158: 1113-1118. PMID: 9258152.
  • Lipschutz, J.H., Foster, B.A., Cunha, G.R. 1997. Differentiation of Rat Neonatal Ventral Prostates Grown in Organ Culture. Prostate. 32: 35-42. PMID: 9207955.
  • Sugimura, Y., Foster, B.A., Hom, Y., Lipschutz, J.H., Rubin, J.S., Finch, P.W., Aaronson, S.A., Hayashi, N., Kawamura, J., Cunha, G.R. 1996. Keratinocyte Growth Factor (KGF) Can Replace Testosterone in the Ductal Branching Morphogenesis of the Rat Ventral Prostate. International Journal of Developmental Biology. 40: 941-951. PMID: 8946242.
  • Lipschutz, J.H., Samid, D., Cunha, G.R. 1996. Phenylacetate is an Inhibitor of Prostatic Growth and Development in Organ Culture. Journal of Urology. 155: 1762-1770. PMID: 8627880.
  • Lipschutz, J.H., Young, P., Taguchi, O., Cunha, G.R. 1996. Urothelial Transformation into Functional Glandular Tissue In Situ by Instructive Mesenchymal Induction. Kidney International, 49: 59-66. PMID: 8770949.
  • Lipschutz, J.H., Miller, T., Yen, T.S., Vartanian, R.K., Graber, M.L., Damon, L. 1995. Unreliability of the Abdominal Fat Pad Biopsy in the Evaluation of Nephrosis. American Journal of Nephrology, 15;5: 431-435. PMID: 7503144.
  • Lipschutz, J.H., Arieff, A.I. 1994. Reset Osmostat in a Healthy Patient. Annals of Internal Medicine, 120;7: 574-576. PMID: 8116995.
  • Lipschutz, J.H., Canal, D.F., Hawes, R.H., Ruffolo, T.A., Besold, M.A., Lehman, G.A. 1992. Laparoscopic Cholecystectomy and ERCP with Sphincterotomy in an Elderly Patient with Situs Inversus. American Journal of Gastroenterology, 2: 218-220. PMID: 1531164.
  • Lipschutz, J.H., Pascuzzi, R.M., Bognanno, J.R., Putty, T.K. 1991. Bilateral Anterior Cerebral Artery Infarction Resulting from Explosion Type Injury to the Head and Neck. Stroke, 22: 813-815. PMID: 2057983.