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Publications

Development of a prognostic multiomic biomarker of progression-free survival in advanced non-small cell lung cancer patients treated with first line immunotherapy.
Scientific reports. 2025 Oct 3;15(1):34591; Authors: Singh A, Horng H, Roshkovan L, Hershman M, Cohen EA, Aggarwal C, Carpenter EL, Katz SI, Kontos D
Cell-free DNA methylomics identify tissue injury patterns in pediatric ARDS.
JCI insight. 2025 Oct 22;10(20) Epub 2025 Sep 2; Authors: Yehya N, Till JE, Srivastava N, Zhang D, Christie JD, Carpenter EL, Mangalmurti NS, Zhou W
Next-Generation Sequencing of Intraoperatively Acquired Cerebrospinal Fluid and Matched Tumor Tissue in Patients Undergoing Surgical Resection for Glioblastoma.
JCO precision oncology. 2025 Sep;9:e2500456 Epub 2025 Sep 4; Authors: Carpenter EL, Till JE, Ballinger D, Macia C, Leche C, Yin M, Desai AS, Prior T, Mansour M, McCoy E, Patel T, Shah S, Chen HI, Zager E, Jackson C, Brem S, Binder ZA, O'Rourke DM, Amankulor N, Beaubier N, Bagley SJ
A phase 1 dual-dose escalation study of radiation and nab-paclitaxel in patients with unresectable and borderline resectable pancreatic cancer.
Cancer. 2025 Jun 15;131(12):e35936; Authors: Amit U, Metz JM, Plastaras JP, Gheewala R, Teitelbaum U, Damjanov N, Vollmer C, Schneider CJ, Lee MK 4th, O'Hara M, Reiss-Binder K, Carpenter EL, Karasic TB, Konski A, Wileyto EP, Ben-Josef E
miRNA panel from HER2+ and CD24+ plasma extracellular vesicle subpopulations as biomarkers of early-stage breast cancer.
Breast cancer research : BCR. 2025 May 22;27(1):90; Authors: Spychalski GB, Lin AA, Yang SJ, Shen H, Rosario J, Tien K, French K, Ghali M, Yee S, Yin M, Feldman MD, Conant EF, Weinstein SP, Carpenter EL, Issadore D, Nayak A
Corticosteroid-Dependent Association between Prognostic Peripheral Blood Cell-Free DNA Levels and Neutrophil-Mediated NETosis in Patients with Glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2025 Apr 1;31(7):1292-1304; Authors: Till JE, Seewald NJ, Yazdani Z, Wang Z, Ballinger D, Samberg H, Dandu S, Macia C, Yin M, Abdalla A, Prior T, Shah SS, Patel T, McCoy E, Mansour M, Wills CA, Bochenek V, Serrano J, Snuderl M, Phillips RE, O'Rourke DM, Amankulor NM, Nabavizadeh A, Desai AS, Gollomp K, Binder ZA, Zhou W, Bagley SJ, Carpenter EL
Electronic Medical Record-Based Nudge Intervention to Increase Comprehensive Molecular Genotyping in Patients With Metastatic Non-Small Cell Lung Cancer: Results From a Prospective Clinical Trial.
JCO oncology practice. 2024 Dec;20(12):1620-1628 Epub 2024 Jul 3; Authors: Marmarelis ME, Scholes DG, McWilliams TL, Hwang WT, Kosteva J, Costello MR, Sun L, Singh AP, Lau-Min KS, Doucette A, Gabriel PE, Martella AO, Roy MA, Thompson JC, Cohen RB, Dougherty DW, Shulman LN, Langer CJ, Bekelman JE, Carpenter EL, Aggarwal C
Circulating KRAS G12D but not G12V is associated with survival in metastatic pancreatic ductal adenocarcinoma.
Nature communications. 2024 Jul 9;15(1):5763; Authors: Till JE, McDaniel L, Chang C, Long Q, Pfeiffer SM, Lyman JP, Padrón LJ, Maurer DM, Yu JX, Spencer CN, Gherardini PF, Da Silva DM, LaVallee TM, Abbott C, Chen RO, Boyle SM, Bhagwat N, Cannas S, Sagreiya H, Li W, Yee SS, Abdalla A, Wang Z, Yin M, Ballinger D, Wissel P, Eads J, Karasic T, Schneider C, O'Dwyer P, Teitelbaum U, Reiss KA, Rahma OE, Fisher GA, Ko AH, Wainberg ZA, Wolff RA, O'Reilly EM, O'Hara MH, Cabanski CR, Vonderheide RH, Carpenter EL
Combined JAK inhibition and PD-1 immunotherapy for non-small cell lung cancer patients.
Science (New York, N.Y.). 2024 Jun 21;384(6702):eadf1329; Authors: Mathew D, Marmarelis ME, Foley C, Bauml JM, Ye D, Ghinnagow R, Ngiow SF, Klapholz M, Jun S, Zhang Z, Zorc R, Davis CW, Diehn M, Giles JR, Huang AC, Hwang WT, Zhang NR, Schoenfeld AJ, Carpenter EL, Langer CJ, Wherry EJ, Minn AJ
Brief Report: Impact of Reflex Testing on Tissue-Based Molecular Genotyping in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer.
Clinical lung cancer. 2024 May;25(3):262-265.e2 Epub 2024 Mar 12; Authors: Marmarelis ME, Scholes DG, McGrath CM, Priore SF, Roth JJ, Feldman M, Morrissette JJD, Litzky L, Deshpande C, Thompson JC, Doucette A, Gabriel PE, Sun L, Singh AP, Cohen RB, Langer CJ, Carpenter EL, Aggarwal C
Inflammatory and tissue injury marker dynamics in pediatric acute respiratory distress syndrome.
The Journal of clinical investigation. 2024 Apr 4;134(10); Authors: Yehya N, Booth TJ, Ardhanari GD, Thompson JM, Lam LKM, Till JE, Mai MV, Keim G, McKeone DJ, Halstead ES, Lahni P, Varisco BM, Zhou W, Carpenter EL, Christie JD, Mangalmurti NS
Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer.
20a4 Gut. 2024 Mar 7;73(4):639-648; Authors: Ben-Ami R, Wang QL, Zhang J, Supplee JG, Fahrmann JF, Lehmann-Werman R, Brais LK, Nowak J, Yuan C, Loftus M, Babic A, Irajizad E, Davidi T, Zick A, Hubert A, Neiman D, Piyanzin S, Gal-Rosenberg O, Horn A, Shemer R, Glaser B, Boos N, Jajoo K, Lee L, Clancy TE, Rubinson DA, Ng K, Chabot JA, Kastrinos F, Kluger M, Aguirre AJ, Jänne PA, Bardeesy N, Stanger B, O'Hara MH, Till J, Maitra A, Carpenter EL, Bullock AJ, Genkinger J, Hanash SM, Paweletz CP, Dor Y, Wolpin BM
The Clinical Implications of Reversions in Patients with Advanced Pancreatic Cancer and Pathogenic Variants in BRCA1, BRCA2, or PALB2 after Progression on Rucaparib.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Dec 15;29(24):5207-5216; Authors: Brown TJ, Yablonovitch A, Till JE, Yen J, Kiedrowski LA, Hood R, O'Hara MH, Teitelbaum U, Karasic TB, Schneider C, Carpenter EL, Nathanson K, Domchek SM, Reiss KA
Molecular response assessment using circulating tumor DNA (ctDNA) in advanced solid tumors.
British journal of cancer. 2023 Dec;129(12):1893-1902 Epub 2023 Oct 3; Authors: Thompson JC, Scholes DG, Carpenter EL, Aggarwal C
Modeling and optimization of parallelized immunomagnetic nanopore sorting for surface marker specific isolation of extracellular vesicles from complex media.
Scientific reports. 2023 Aug 16;13(1):13292; Authors: Lin AA, Shen H, Spychalski G, Carpenter EL, Issadore D
Association Between Availability of Molecular Genotyping Results and Overall Survival in Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer.
JCO precision oncology. 2023 Jul;7:e2300191; Authors: Aggarwal C, Marmarelis ME, Hwang WT, Scholes DG, McWilliams TL, Singh AP, Sun L, Kosteva J, Costello MR, Cohen RB, Langer CJ, Doucette A, Gabriel PN, Shulman LN, Rendle KA, Thompson JC, Bekelman JE, Carpenter EL
Distinguishing Progression from Pseudoprogression in Glioblastoma Using (18)F-Fluciclovine PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2023 Jun;64(6):852-858 Epub 2022 Dec 22; Authors: Nabavizadeh A, Bagley SJ, Doot RK, Ware JB, Young AJ, Ghodasara S, Zhao C, Anderson H, Schubert E, Carpenter EL, Till J, Henderson F Jr, Pantel AR, Chen HI, Lee JYK, Amankulor NM, O'Rourke DM, Desai A, Nasrallah MP, Brem S
Parallelized immunomagnetic nanopore sorting: modeling, scaling, and optimization of surface marker specific isolation of extracellular vesicles from complex media.
Research square. 2023 May 16; Authors: Lin AA, Shen H, Spychalski G, Carpenter EL, Issadore D
Outcomes and clinicopathologic characteristics associated with disseminated tumor cells in bone marrow after neoadjuvant chemotherapy in high-risk early stage breast cancer: the I-SPY SURMOUNT study.
Breast cancer research and treatment. 2023 Apr;198(2):383-390 Epub 2023 Jan 23; Authors: Magbanua MJM, van 't Veer L, Clark AS, Chien AJ, Boughey JC, Han HS, Wallace A, Beckwith H, Liu MC, Yau C, Wileyto EP, Ordonez A, Solanki TI, Hsiao F, Lee JC, Basu A, Brown Swigart L, Perlmutter J, Delson AL, Bayne L, Deluca S, Yee SS, Carpenter EL, Esserman LJ, Park JW, Chodosh LA, DeMichele A
Clinical utility of plasma cell-free DNA in gliomas.
Neuro-oncology advances. 2022 Nov;4(Suppl 2):ii41-ii44 Epub 2022 Nov 11; Authors: Carpenter EL, Bagley SJ
Correction: THBS2 as a prognostic biomarker for patients diagnosed with metastatic pancreatic ductal adenocarcinoma.
Oncotarget. 2022 Nov 2;13:1187; Authors: Gimotty PA, Till JE, Udgata S, Takenaka N, Yee SS, LaRiviere MJ, O'Hara MH, Reiss KA, O'Dwyer P, Katona BW, Herman D, Carpenter EL, Zaret KS
Extracellular Vesicle-Based Multianalyte Liquid Biopsy as a Diagnostic for Cancer.
Annual review of biomedical data science. 2022 Aug 10;5:269-292 Epub 2022 May 13; Authors: Lin AA, Nimgaonkar V, Issadore D, Carpenter EL
Changes in Circulating Tumor DNA Reflect Clinical Benefit Across Multiple Studies of Patients With Non-Small-Cell Lung Cancer Treated With Immune Checkpoint Inhibitors.
JCO precision oncology. 2022 Aug;6:e2100372; Authors: Vega DM, Nishimura KK, Zariffa N, Thompson JC, Hoering A, Cilento V, Rosenthal A, Anagnostou V, Baden J, Beaver JA, Chaudhuri AA, Chudova D, Fine AD, Fiore J, Hodge R, Hodgson D, Hunkapiller N, Klass DM, Kobie J, Peña C, Pennello G, Peterman N, Philip R, Quinn KJ, Raben D, Rosner GL, Sausen M, Tezcan A, Xia Q, Yi J, Young AG, Stewart MD, Carpenter EL, Aggarwal C, Allen J
Biomarker Testing, Treatment Uptake, and Survival Among Patients With Urothelial Cancer Receiving Gene-Targeted Therapy.
JAMA oncology. 2022 Jul 1;8(7):1070-1072; Authors: Nimgaonkar V, Hubbard RA, Carpenter EL, Mamtani R
Transcriptional profiling of single tumour cells from pleural effusions reveals heterogeneity of epithelial to mesenchymal transition and extra-cellular matrix marker expression.
Clinical and translational medicine. 2022 Jul;12(7):e888; Authors: Sen M, Hausler RM, Dulmage K, Black TA, Murphy W, Pletcher CH Jr, Wang L, Chen C, Yee SS, Bornheimer SJ, Maxwell KN, Stanger BZ, Moore JS, Thompson JC, Carpenter EL
Multianalyte Prognostic Signature Including Circulating Tumor DNA and Circulating Tumor Cells in Patients With Advanced Pancreatic Adenocarcinoma.
JCO precision oncology. 2022 Jul;6:e2200060; Authors: Chapin WJ, Till JE, Hwang WT, Eads JR, Karasic TB, O'Dwyer PJ, Schneider CJ, Teitelbaum UR, Romeo J, Black TA, Christensen TE, Redlinger Tabery C, Anderson A, Slade M, LaRiviere M, Yee SS, Reiss KA, O'Hara MH, Carpenter EL
Development of a robust radiomic biomarker of progression-free survival in advanced non-small cell lung cancer patients treated with first-line immunotherapy.
2066 Scientific reports. 2022 Jun 15;12(1):9993; Authors: Singh A, Horng H, Roshkovan L, Weeks JK, Hershman M, Noël P, Luna JM, Cohen EA, Pantalone L, Shinohara RT, Bauml JM, Thompson JC, Aggarwal C, Carpenter EL, Katz SI, Kontos D
Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance.
The EMBO journal. 2022 Apr 19;41(8):e108272 Epub 2022 Feb 25; Authors: Çoku J, Booth DM, Skoda J, Pedrotty MC, Vogel J, Liu K, Vu A, Carpenter EL, Ye JC, Chen MA, Dunbar P, Scadden E, Yun TD, Nakamaru-Ogiso E, Area-Gomez E, Li Y, Goldsmith KC, Reynolds CP, Hajnoczky G, Hogarty MD
PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial.
Nature medicine. 2022 Apr;28(4):724-734 Epub 2022 Mar 21; Authors: Narayan V, Barber-Rotenberg JS, Jung IY, Lacey SF, Rech AJ, Davis MM, Hwang WT, Lal P, Carpenter EL, Maude SL, Plesa G, Vapiwala N, Chew A, Moniak M, Sebro RA, Farwell MD, Marshall A, Gilmore J, Lledo L, Dengel K, Church SE, Hether TD, Xu J, Gohil M, Buckingham TH, Yee SS, Gonzalez VE, Kulikovskaya I, Chen F, Tian L, Tien K, Gladney W, Nobles CL, Raymond HE, Prostate Cancer Cellular Therapy Program Investigators, Hexner EO, Siegel DL, Bushman FD, June CH, Fraietta JA, Haas NB
Plasma Genotyping at the Time of Diagnostic Tissue Biopsy Decreases Time-to-Treatment in Patients With Advanced NSCLC-Results From a Prospective Pilot Study.
JTO clinical and research reports. 2022 Apr;3(4):100301 Epub 2022 Mar 8; Authors: Thompson JC, Aggarwal C, Wong J, Nimgaonkar V, Hwang WT, Andronov M, Dibardino DM, Hutchinson CT, Ma KC, Lanfranco A, Moon E, Haas AR, Singh AP, Ciunci CA, Marmarelis M, D'Avella C, Cohen JV, Bauml JM, Cohen RB, Langer CJ, Vachani A, Carpenter EL
MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma.
Cancer discovery. 2022 Feb;12(2):542-561 Epub 2021 Sep 22; Authors: Maddipati R, Norgard RJ, Baslan T, Rathi KS, Zhang A, Saeid A, Higashihara T, Wu F, Kumar A, Annamalai V, Bhattacharya S, Raman P, Adkisson CA, Pitarresi JR, Wengyn MD, Yamazoe T, Li J, Balli D, LaRiviere MJ, Ngo TC, Folkert IW, Millstein ID, Bermeo J, Carpenter EL, McAuliffe JC, Oktay MH, Brekken RA, Lowe SW, Iacobuzio-Donahue CA, Notta F, Stanger BZ
Impact of Interobserver Variability in Manual Segmentation of Non-Small Cell Lung Cancer (NSCLC) Applying Low-Rank Radiomic Representation on Computed Tomography.
Cancers. 2021 Nov 28;13(23); Authors: Hershman M, Yousefi B, Serletti L, Galperin-Aizenberg M, Roshkovan L, Luna JM, Thompson JC, Aggarwal C, Carpenter EL, Kontos D, Katz SI
Racial Disparities in 30-Day Outcomes Following Index Admission for COVID-19.
Frontiers in medicine. 2021;8:750650 Epub 2021 Nov 2; Authors: Nimgaonkar V, Thompson JC, Pantalone L, Cook T, Kontos D, McCarthy AM, Carpenter EL
EUS-based Pancreatic Cancer Surveillance in BRCA1/BRCA2/PALB2/ATM Carriers Without a Family History of Pancreatic Cancer.
Cancer prevention research (Philadelphia, Pa.). 2021 Nov;14(11):1033-1040 Epub 2021 Aug 2; Authors: Katona BW, Long JM, Ahmad NA, Attalla S, Bradbury AR, Carpenter EL, Clark DF, Constantino G, Das KK, Domchek SM, Dudzik C, Ebrahimzadeh J, Ginsberg GG, Heiman J, Kochman ML, Maxwell KN, McKenna DB, Powers J, Shah PD, Wangensteen KJ, Rustgi AK
Optimization of Sources of Circulating Cell-Free DNA Variability for Downstream Molecular Analysis.
The Journal of molecular diagnostics : JMD. 2021 Nov;23(11):1545-1552 Epub 2021 Aug 25; Authors: Till JE, Black TA, Gentile C, Abdalla A, Wang Z, Sangha HK, Roth JJ, Sussman R, Yee SS, O'Hara MH, Thompson JC, Aggarwal C, Hwang WT, Elenitoba-Johnson KSJ, Carpenter EL
THSB2 as a prognostic biomarker for patients diagnosed with metastatic pancreatic ductal adenocarcinoma.
Oncotarget. 2021 Oct 26;12(22):2266-2272; Authors: Gimotty PA, Till JE, Udgata S, Takenaka N, Yee SS, LaRiviere MJ, O'Hara MH, Reiss KA, O'Dwyer P, Katona BW, Herman D, Carpenter EL, Zaret KS
Plasma Cell-Free DNA Genotyping: From an Emerging Concept to a Standard-of-Care Tool in Metastatic Non-Small Cell Lung Cancer.
The oncologist. 2021 Oct;26(10):e1812-e1821 Epub 2021 Jul 26; Authors: Gray J, Thompson JC, Carpenter EL, Elkhouly E, Aggarwal C
Blood-based gene expression signature associated with metastatic castrate-resistant prostate cancer patient response to abiraterone plus prednisone or enzalutamide.
Prostate cancer and prostatic diseases. 2021 Jun;24(2):448-456 Epub 2020 Oct 2; Authors: Haas NB, LaRiviere MJ, Buckingham TH, Cherkas Y, Calara-Nielsen K, Foulk B, Patel J, Gross S, Smirnov D, Vaughn DJ, Amaravadi R, Wellen KE, Savitch SL, Majmundar KJ, Black TA, Yee SS, He M, Min EJ, Long Q, Jones JO, Pal SK, Carpenter EL
Combining radiomic phenotypes of non-small cell lung cancer with liquid biopsy data may improve prediction of response to EGFR inhibitors.
Scientific reports. 2021 May 11;11(1):9984; Authors: Yousefi B, LaRiviere MJ, Cohen EA, Buckingham TH, Yee SS, Black TA, Chien AL, Noël P, Hwang WT, Katz SI, Aggarwal C, Thompson JC, Carpenter EL, Kontos D
Serial Monitoring of Circulating Tumor DNA by Next-Generation Gene Sequencing as a Biomarker of Response and Survival in Patients With Advanced NSCLC Receiving Pembrolizumab-Based Therapy.
JCO precision oncology. 2021;5 Epub 2021 Mar 19; Authors: Thompson JC, Carpenter EL, Silva BA, Rosenstein J, Chien AL, Quinn K, Espenschied CR, Mak A, Kiedrowski LA, Lefterova M, Nagy RJ, Katz SI, Yee SS, Black TA, Singh AP, Ciunci CA, Bauml JM, Cohen RB, Langer CJ, Aggarwal C
Systemic inflammation is a determinant of outcomes of CD40 agonist-based therapy in pancreatic cancer patients.
JCI insight. 2021 Mar 8;6(5); Authors: Wattenberg MM, Herrera VM, Giannone MA, Gladney WL, Carpenter EL, Beatty GL
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Plasma Tumor Mutation Burden and Response to Pembrolizumab-Response.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2021 Mar 1;27(5):1581; Authors: Aggarwal C, Thompson JC, Carpenter EL
THBS2/CA19-9 Detecting Pancreatic Ductal Adenocarcinoma at Diagnosis Underperforms in Prediagnostic Detection: Implications for Biomarker Advancement.
Cancer prevention research (Philadelphia, Pa.). 2021 Feb;14(2):223-232 Epub 2020 Oct 16; Authors: Udgata S, Takenaka N, Bamlet WR, Oberg AL, Yee SS, Carpenter EL, Herman D, Kim J, Petersen GM, Zaret KS
A Pilot Study of Galunisertib plus Stereotactic Body Radiotherapy in Patients with Advanced Hepatocellular Carcinoma.
Molecular cancer therapeutics. 2021 Feb;20(2):389-397 Epub 2020 Dec 2; Authors: Reiss KA, Wattenberg MM, Damjanov N, Prechtel Dunphy E, Jacobs-Small M, Lubas MJ, Robinson J, Dicicco L, Garcia-Marcano L, Giannone MA, Karasic TB, Furth EE, Carpenter EL, Wojcieszynski AP, Vonderheide RH, Beatty GL, Ben-Josef E
Association of plasma cell-free DNA with survival in patients with IDH wild-type glioblastoma.
Neuro-oncology advances. 2021 Jan-Dec;3(1):vdab011 Epub 2021 Jan 16; Authors: Bagley SJ, Till J, Abdalla A, Sangha HK, Yee SS, Freedman J, Black TA, Hussain J, Binder ZA, Brem S, Desai AS, O'Rourke DM, Long Q, Nabavizadeh SA, Carpenter EL
CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study.
The Lancet. Oncology. 2021 Jan;22(1):118-131; Authors: O'Hara MH, O'Reilly EM, Varadhachary G, Wolff RA, Wainberg ZA, Ko AH, Fisher G, Rahma O, Lyman JP, Cabanski CR, Mick R, Gherardini PF, Kitch LJ, Xu J, Samuel T, Karakunnel J, Fairchild J, Bucktrout S, LaVallee TM, Selinsky C, Till JE, Carpenter EL, Alanio C, Byrne KT, Chen RO, Trifan OC, Dugan U, Horak C, Hubbard-Lucey VM, Wherry EJ, Ibrahim R, Vonderheide RH
Type 1 conventional dendritic cells are systemically dysregulated early in pancreatic carcinogenesis.
The Journal of experimental medicine. 2020 Aug 3;217(8); Authors: Lin JH, Huffman AP, Wattenberg MM, Walter DM, Carpenter EL, Feldser DM, Beatty GL, Furth EE, Vonderheide RH
A Multianalyte Panel Consisting of Extracellular Vesicle miRNAs and mRNAs, cfDNA, and CA19-9 Shows Utility for Diagnosis and Staging of Pancreatic Ductal Adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Jul 1;26(13):3248-3258 Epub 2020 Apr 16; Authors: Yang Z, LaRiviere MJ, Ko J, Till JE, Christensen T, Yee SS, Black TA, Tien K, Lin A, Shen H, Bhagwat N, Herman D, Adallah A, O'Hara MH, Vollmer CM, Katona BW, Stanger BZ, Issadore D, Carpenter EL
Plasma Tumor Mutation Burden and Response to Pembrolizumab-Response.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Jul 1;26(13):3492; Authors: Aggarwal C, Thompson JC, Carpenter EL
Baseline Plasma Tumor Mutation Burden Predicts Response to Pembrolizumab-based Therapy in Patients with Metastatic Non-Small Cell Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 May 15;26(10):2354-2361 Epub 2020 Feb 26; Authors: Aggarwal C, Thompson JC, Chien AL, Quinn KJ, Hwang WT, Black TA, Yee SS, Christensen TE, LaRiviere MJ, Silva BA, Banks KC, Nagy RJ, Helman E, Berman AT, Ciunci CA, Singh AP, Wasser JS, Bauml JM, Langer CJ, Cohen RB, Carpenter EL
Plasma cfDNA in Glioblastoma-Response.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 May 1;26(9):2276; Authors: Bagley SJ, Carpenter EL
Highly specific enrichment of rare nucleic acid fractions using Thermus thermophilus argonaute with applications in cancer diagnostics.
Nucleic acids research. 2020 Feb 28;48(4):e19; Authors: Song J, Hegge JW, Mauk MG, Chen J, Till JE, Bhagwat N, Azink LT, Peng J, Sen M, Mays J, Carpenter EL, van der Oost J, Bau HH
Clinical Utility of Plasma Cell-Free DNA in Adult Patients with Newly Diagnosed Glioblastoma: A Pilot Prospective Study.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Jan 15;26(2):397-407 Epub 2019 Oct 30; Authors: Bagley SJ, Nabavizadeh SA, Mays JJ, Till JE, Ware JB, Levy S, Sarchiapone W, Hussain J, Prior T, Guiry S, Christensen T, Yee SS, Nasrallah MP, Morrissette JJD, Binder ZA, O'Rourke DM, Cucchiara AJ, Brem S, Desai AS, Carpenter EL
Imaging and histopathologic correlates of plasma cell-free DNA concentration and circulating tumor DNA in adult patients with newly diagnosed glioblastoma.
Neuro-oncology advances. 2020 Jan-Dec;2(1):vdaa016 Epub 2020 Feb 27; Authors: Nabavizadeh SA, Ware JB, Guiry S, Nasrallah MP, Mays JJ, Till JE, Hussain J, Abdalla A, Yee SS, Binder ZA, O'Rourke DM, Brem S, Desai AS, Wolf R, Carpenter EL, Bagley SJ
Correction: Flow based single cell analysis of the immune landscape distinguishes Barrett's esophagus from adjacent normal tissue.
Oncotarget. 2019 Aug 20;10(49):5119; Authors: Sen M, Hahn F, Black TA, DeMarshall M, Porter W, Snowden E, Yee SS, Tong F, Ferguson M, Fleshman EN, Nakagawa H, Falk GW, Ginsberg GG, Kochman ML, Blaesius R, Rustgi AK, Carpenter EL
Flow based single cell analysis of the immune landscape distinguishes Barrett's esophagus from adjacent normal tissue.
200e Oncotarget. 2019 Jun 4;10(38):3592-3604; Authors: Sen M, Hahn F, Black TA, DeMarshall M, Porter W, Snowden E, Yee SS, Tong F, Ferguson M, Fleshman EN, Nakagawa H, Falk GW, Ginsberg GG, Kochman ML, Blaesius R, Rustgi AK, Carpenter EL
Hepatocytes direct the formation of a pro-metastatic niche in the liver.
Nature. 2019 Mar;567(7747):249-252 Epub 2019 Mar 6; Authors: Lee JW, Stone ML, Porrett PM, Thomas SK, Komar CA, Li JH, Delman D, Graham K, Gladney WL, Hua X, Black TA, Chien AL, Majmundar KS, Thompson JC, Yee SS, O'Hara MH, Aggarwal C, Xin D, Shaked A, Gao M, Liu D, Borad MJ, Ramanathan RK, Carpenter EL, Ji A, de Beer MC, de Beer FC, Webb NR, Beatty GL
Clinical Implications of Plasma-Based Genotyping With the Delivery of Personalized Therapy in Metastatic Non-Small Cell Lung Cancer.
JAMA oncology. 2019 Feb 1;5(2):173-180; Authors: Aggarwal C, Thompson JC, Black TA, Katz SI, Fan R, Yee SS, Chien AL, Evans TL, Bauml JM, Alley EW, Ciunci CA, Berman AT, Cohen RB, Lieberman DB, Majmundar KS, Savitch SL, Morrissette JJD, Hwang WT, Elenitoba-Johnson KSJ, Langer CJ, Carpenter EL
Measurement and immunophenotyping of pleural fluid EpCAM-positive cells and clusters for the management of non-small cell lung cancer patients.
Lung cancer (Amsterdam, Netherlands). 2019 Jan;127:25-33 Epub 2018 Nov 19; Authors: Thompson JC, Fan R, Black T, Yu GH, Savitch SL, Chien A, Yee SS, Sen M, Hwang WT, Katz SI, Feldman M, Vachani A, Carpenter EL
Rare Event Phenotyping and Molecular Characterization: Circulating Tumor Cells.
Methods in molecular biology (Clifton, N.J.). 2019;2032:213-226; Authors: Sen M, Wang L, Yu L, Carpenter EL
An integrated enrichment system to facilitate isolation and molecular characterization of single cancer cells from whole blood.
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2018 Dec;93(12):1226-1233; Authors: Yu L, Sa S, Wang L, Dulmage K, Bhagwat N, Yee SS, Sen M, Pletcher CH Jr, Moore JS, Saksena S, Dixon EP, Carpenter EL
miRNA Profiling of Magnetic Nanopore-Isolated Extracellular Vesicles for the Diagnosis of Pancreatic Cancer.
Cancer research. 2018 Jul 1;78(13):3688-3697 Epub 2018 May 7; Authors: Ko J, Bhagwat N, Black T, Yee SS, Na YJ, Fisher S, Kim J, Carpenter EL, Stanger BZ, Issadore D
An integrated flow cytometry-based platform for isolation and molecular characterization of circulating tumor single cells and clusters.
Scientific reports. 2018 Mar 22;8(1):5035; Authors: Bhagwat N, Dulmage K, Pletcher CH Jr, Wang L, DeMuth W, Sen M, Balli D, Yee SS, Sa S, Tong F, Yu L, Moore JS, Stanger BZ, Dixon EP, Carpenter EL
Feasibility of monitoring advanced melanoma patients using cell-free DNA from plasma.
Pigment cell & melanoma research. 2018 Jan;31(1):73-81 Epub 2017 Oct 23; Authors: Gangadhar TC, Savitch SL, Yee SS, Xu W, Huang AC, Harmon S, Lieberman DB, Soucier D, Fan R, Black TA, Morrissette JJD, Salathia N, Waters J, Zhang S, Toung J, van Hummelen P, Fan JB, Xu X, Amaravadi RK, Schuchter LM, Karakousis GC, Hwang WT, Carpenter EL
Influence of TP53 Mutation on Survival in Patients With Advanced EGFR-Mutant Non-Small-Cell Lung Cancer.
JCO precision oncology. 2018;2018 Epub 2018 Aug 31; Authors: Aggarwal C, Davis CW, Mick R, Thompson JC, Ahmed S, Jeffries S, Bagley S, Gabriel P, Evans TL, Bauml JM, Ciunci C, Alley E, Morrissette JJD, Cohen RB, Carpenter EL, Langer CJ
Combining Machine Learning and Nanofluidic Technology To Diagnose Pancreatic Cancer Using Exosomes.
ACS nano. 2017 Nov 28;11(11):11182-11193 Epub 2017 Oct 17; Authors: Ko J, Bhagwat N, Yee SS, Ortiz N, Sahmoud A, Black T, Aiello NM, McKenzie L, O'Hara M, Redlinger C, Romeo J, Carpenter EL, Stanger BZ, Issadore D
A magnetic micropore chip for rapid (<1 hour) unbiased circulating tumor cell isolation and in situ RNA analysis.
Lab on a chip. 2017 Sep 12;17(18):3086-3096; Authors: Ko J, Bhagwat N, Yee SS, Black T, Redlinger C, Romeo J, O'Hara M, Raj A, Carpenter EL, Stanger BZ, Issadore D
Flow Cytometric Methods for Circulating Tumor Cell Isolation and Molecular Analysis.
Advances in experimental medicine and biology. 2017;994:105-118; Authors: Bhagwat N, Carpenter EL
Enumeration, Dielectrophoretic Capture, and Molecular Analysis of Circulating Tumor Cells.
Methods in molecular biology (Clifton, N.J.). 2017;1634:193-202; Authors: Yee SS, Carpenter EL
Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2016 Dec 1;22(23):5772-5782 Epub 2016 Sep 6; Authors: Thompson JC, Yee SS, Troxel AB, Savitch SL, Fan R, Balli D, Lieberman DB, Morrissette JD, Evans TL, Bauml J, Aggarwal C, Kosteva JA, Alley E, Ciunci C, Cohen RB, Bagley S, Stonehouse-Lee S, Sherry VE, Gilbert E, Langer C, Vachani A, Carpenter EL
A novel approach for next-generation sequencing of circulating tumor cells.
Molecular genetics & genomic medicine. 2016 Jul;4(4):395-406 Epub 2016 Feb 28; Authors: Yee SS, Lieberman DB, Blanchard T, Rader J, Zhao J, Troxel AB, DeSloover D, Fox AJ, Daber RD, Kakrecha B, Sukhadia S, Belka GK, DeMichele AM, Chodosh LA, Morrissette JJ, Carpenter EL
Circulating Tumor Cells, DNA, and mRNA: Potential for Clinical Utility in Patients With Melanoma.
207e The oncologist. 2016 Jan;21(1):84-94 Epub 2015 Nov 27; Authors: Xu MJ, Dorsey JF, Amaravadi R, Karakousis G, Simone CB 2nd, Xu X, Xu W, Carpenter EL, Schuchter L, Kao GD
Dielectrophoretic capture and genetic analysis of single neuroblastoma tumor cells.
Frontiers in oncology. 2014;4:201 Epub 2014 Jul 31; Authors: Carpenter EL, Rader J, Ruden J, Rappaport EF, Hunter KN, Hallberg PL, Krytska K, O'Dwyer PJ, Mosse YP
Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 Nov 15;19(22):6173-82 Epub 2013 Sep 17; Authors: Rader J, Russell MR, Hart LS, Nakazawa MS, Belcastro LT, Martinez D, Li Y, Carpenter EL, Attiyeh EF, Diskin SJ, Kim S, Parasuraman S, Caponigro G, Schnepp RW, Wood AC, Pawel B, Cole KA, Maris JM
Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma.
Nature genetics. 2012 Oct;44(10):1126-30 Epub 2012 Sep 2; Authors: Diskin SJ, Capasso M, Schnepp RW, Cole KA, Attiyeh EF, Hou C, Diamond M, Carpenter EL, Winter C, Lee H, Jagannathan J, Latorre V, Iolascon A, Hakonarson H, Devoto M, Maris JM
Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma.
Science translational medicine. 2011 Nov 9;3(108):108ra114; Authors: Bresler SC, Wood AC, Haglund EA, Courtright J, Belcastro LT, Plegaria JS, Cole K, Toporovskaya Y, Zhao H, Carpenter EL, Christensen JG, Maris JM, Lemmon MA, Mossé YP
Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation.
Journal of translational medicine. 2009 Nov 11;7:93; Authors: Carpenter EL, Mick R, Rüter J, Vonderheide RH
Collapse of the CD27+ B-cell compartment associated with systemic plasmacytosis in patients with advanced melanoma and other cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 Jul 1;15(13):4277-87 Epub 2009 Jun 23; Authors: Carpenter EL, Mick R, Rech AJ, Beatty GL, Colligon TA, Rosenfeld MR, Kaplan DE, Chang KM, Domchek SM, Kanetsky PA, Fecher LA, Flaherty KT, Schuchter LM, Vonderheide RH
Functional analysis of CD8+ T cell responses to the onconeural self protein cdr2 in patients with paraneoplastic cerebellar degeneration.
Journal of neuroimmunology. 2008 Jan;193(1-2):173-82 Epub 2007 Nov 28; Authors: Carpenter EL, Vance BA, Klein RS, Voloschin A, Dalmau J, Vonderheide RH
Telomerase-specific T-cell immunity in breast cancer: effect of vaccination on tumor immunosurveillance.
Cancer research. 2007 Nov 1;67(21):10546-55; Authors: Domchek SM, Recio A, Mick R, Clark CE, Carpenter EL, Fox KR, DeMichele A, Schuchter LM, Leibowitz MS, Wexler MH, Vance BA, Beatty GL, Veloso E, Feldman MD, Vonderheide RH
Telomerase-based immunotherapy of cancer.
Expert opinion on biological therapy. 2006 Oct;6(10):1031-9; Authors: Carpenter EL, Vonderheide RH