11 40 3d 3d 21 12 12 2 8 1c 3b 5b b b 38 74 Lou J. Soslowsky | Faculty | McKay Orthopaedic Research Laboratory | Perelman School of Medicine at the 40 University of Pennsylvania 54 70 6d 76 69 48 49 2 4f 5c 58 d 77 d 5f d 38 3e 40 3d 36 1e 14 17 1f 2 25 d 9 2 8 1e
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Lou J. Soslowsky, Ph.D.

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Fairhill Professor
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Department: Orthopaedic Surgery
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1f Graduate Group Affiliations 8 a
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46 Contact information
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McKay Orthopaedic Research Laboratory
1a 307A Stemmler Hall
3a 3450 Hamilton Walk
Philadelphia, PA 19104-6081
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2e Office: 215-898-8654
32 Fax: 215-573-2133
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18 Publications
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13 Education:
21 c Diploma c
34 East Brunswick High School , 1982.
21 9 B.S. 22 (Engineering Mechanics) c
2c Columbia University, 1986.
21 9 M.S. 22 (Engineering Mechanics) c
2c Columbia University, 1987.
21 b M.Phil c
2c Columbia University, 1989.
21 a Ph.D. 3f (Engineering Mech./Biomechanics, Mentor: Van C. Mow) c
2c Columbia University, 1991.
21 a Cert. 31 (Academic Medicine Leadership Program) c
4b Wharton School of the University of Pennsylvania , 2008.
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Description of Research Expertise

80 orthopaedic research, orthopaedic biomechanics and tissue engineering, tendons and ligaments, shoulder and elbow
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Selected Publications

139 Darrieutort-Laffite C, Weiss SN, Nuss CA, Newton JB, Eekhoff JD, Soslowsky LJ.: Decorin Knockdown Improves Aged Tendon Healing by Enhancing Recovery of Viscoelastic Properties, While Biglycan May Not. Ann Biomed Eng 53(3): 622-33, Mar 2025.

140 Tamburro MK, Bonilla KA, Shetye SS, Leahy TP, Eekhoff JD, Kim MS, Petucci C, Tobias JW, Farber DC, Soslowsky LJ: Moderate- and High-Speed Treadmill Running Exercise Have Minimal Impact on Rat Achilles Tendon. J Orthop Res. 43(3): 519-30, Mar 2025.

132 DiStefano MS, Weiss SN, Nuss CA, Betts RL, Han B, Kuntz AF, Soslowsky LJ: Mature murine supraspinatus tendons demonstrate regional differences in multiscale structure, function and gene expression. PLoS One 20(2): e0318809, Feb 2025.

119 Ye Y, Shetye SS, Birk DE, Soslowsky LJ.: Regulatory Role of Collagen XI in the Establishment of Mechanical Properties of Tendons and Ligaments in Mice Is Tissue Dependent. J Biomech Eng 147: 011003, Jan 2025.

174 Cohen JS, Fung AK, Stein MK, Darrieutort-Laffite C, Weiss SN, Shetye SS, Thurlow NA, Nuss CA, Dyment NA, Soslowsky LJ.: Tendon-targeted knockout of collagen XI disrupts patellar and Achilles tendon structure and mechanical properties during murine postnatal development. Connect Tissue Res Dec 2024.

13d Panebianco CJ, Azar TF, Duffy MP, Nijsure MP, Sharp E, Tamburro MK, Hast M, Shore EM, Mauck RL, Soslowsky LJ, Shuda JR, Gullbrand SE.: Learning on a Limb: An outreach module to engage high school students in orthopaedics. J Orthop Res Nov 2024.

eb Leahy TP, Chenna SS, Soslowsky LJ, Dyment NA.: Focal adhesion kinase regulates tendon cell mechanoresponse and physiological tendon development. FASEB J Sep 2024.

130 Newton JB, Nuss CA, Weiss SN, Betts RL, Sehgal CM, Soslowsky LJ.: In Vivo Photoacoustic Ultrasound (PAUS) Assay for Monitoring Tendon Collagen Compositional Changes during Injury and Healing. Diagnostics (Basel) 14: 1498, Jul 2024.

117 Fung AK, Li Y, Wang J, Leahy TP, Shetye S, Liu XS, Soslowsky LJ: Long-Term effects of reproduction and lactation on the rat supraspinatus tendon and proximal humerus. J Biomech Eng 146(6): 060905, Jun 2024.

149 Carlson JA, Shetye SS, Sun M, Weiss SN, Birk DE, Soslowsky LJ: Collagen V haploinsufficiency in female murine patellar tendons results in altered matrix engagement and cellular density, demonstrating decreased healing. J Orthop Res 42(5): 950-60, May 2024.

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