Weljie Lab

Selected Publications

Lee P, Malik D, Perkons N, Huangyang P, Khare S, Rhoades S, Gong YY, Burrows M, Finan JM, Nissim I, Gade TPF, Weljie AM, Simon MC. Targeting glutamine metabolism slows soft tissue sarcoma growth. Nat Commun. 2020 Jan 24;11(1):498. doi:10.1038/s41467-020-14374-1

Sengupta A, Weljie AM. Metabolism of sleep and aging: Bridging the gap using metabolomics. Nutr Healthy Aging. 2019 Dec 19;5(3):167-184. Review. doi:10.3233/NHA-180043

Sengupta A, Weljie AM. NMR Spectroscopy-Based Metabolic Profiling of Biospecimens. Curr Protoc Protein Sci. 2019 Dec;98(1):e98. doi:10.1002/cpps.98

Malik DM, Rhoades S, Weljie A. Extraction and Analysis of Pan-metabolome Polar Metabolites by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS). Bio Protoc. 2018 Feb 5;8(3). pii: e2715. doi:10.21769/BioProtoc.2715

Gehrman P, Sengupta A, Harders E, Ubeydullah E, Pack AI, Weljie A. Altered diurnal states in insomnia reflect peripheral hyperarousal and metabolic desynchrony: a preliminary study. Sleep. 2018 May 1;41(5). doi:10.1093/sleep/zsy043

Rhoades SD, Nayak K, Zhang SL, Sehgal A, Weljie AM. Circadian- and Light-driven Metabolic Rhythms in Drosophila melanogaster. J Biol Rhythms. 2018 Apr;33(2):126-136. doi:10.1177/0748730417753003

Skarke C, Lahens NF, Rhoades SD, Campbell A, Bittinger K, Bailey A, Hoffmann C, Olson RS, Chen L, Yang G, Price TS, Moore JH, Bushman FD, Greene CS, Grant GR, Weljie AM, FitzGerald GA. A Pilot Characterization of the Human Chronobiome. Sci Rep. 2017 Dec 7;7(1):17141. doi:10.1038/s41598-017-17362-6

Sengupta A, Rhoades SD, Kim EJ, Nayak S, Grant GR, Meerlo P, Weljie AM. Sleep restriction induced energy, methylation and lipogenesis metabolic switches in rat liver. Int J Biochem Cell Biol. 2017 Dec;93:129-135. doi:10.1016/j.biocel.2017.08.014

Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM. Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism. Cell Metab. 2017 May 2;25(5):1206. doi:10.1016/j.cmet.2017.04.023

Rhoades SD, Weljie AM. Comprehensive Optimization of LC-MS Metabolomics Methods Using Design of Experiments (COLMeD). Metabolomics. 2016 Dec;12(12). pii:183. doi:10.1007/s11306-016-1132-4

Rhoades SD, Sengupta A, Weljie AM. Time is ripe: maturation of metabolomics in chronobiology. Curr Opin Biotechnol. 2017 Feb;43:70-76. Review. doi:10.1016/j.copbio.2016.09.007

Sengupta A, Krishnaiah SY, Rhoades S, Growe J, Slaff B, Venkataraman A, Olarerin-George AO, Van Dang C, Hogenesch JB, Weljie AM. Deciphering the Duality of Clock and Growth Metabolism in a Cell Autonomous System Using NMR Profiling of the Secretome. Metabolites. 2016 Jul 27;6(3). pii: E23. doi:10.3390/metabo6030023

Hao D, Sarfaraz MO, Farshidfar F, Bebb DG, Lee CY, Card CM, David M, Weljie AM. Temporal characterization of serum metabolite signatures in lung cancer patients undergoing treatment. Metabolomics. 2016;12:58. doi:10.1007/s11306-016-0961-5

Weljie AM, Meerlo P, Goel N, Sengupta A, Kayser MS, Abel T, Birnbaum MJ, Dinges DF, Sehgal A. Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt. Proc Natl Acad Sci USA. 2015 Feb 24;112(8):2569-74. doi:10.1073/pnas.1417432112

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