New Alzheimer's Animal Model More Closely Mimics Human Disease
Penn study of amyloid plaques and tau tangles aims to accelerate discovery of new therapies
By injecting human Alzheimer's disease brain extracts of pathological tau protein (from postmortem donated tissue) into mice with different amounts of amyloid-β (Aβ) plaques in their brains, researchers from the Perelman School of Medicine at the University of Pennsylvania found that amyloid-β facilitates the interaction between the plaques and abnormal tau. This relationship promotes the spread of mutated tau proteins in neurons, which is the hallmark of long-term Alzheimer’s disease.Read More
ADCC IN THE NEWS
03/06/18The epigenomic landscape of Alzheimer’s disease brains is profiled in a new study from from the Perelman School of Medicine.
01/19/18During President Trump’s medical exam this week, he was given a cognitive test and passed with a perfect score.
12/14/17Researchers have long searched for an explanation for why there is so much variety in how abnormal aggregates of the protein tau occur in the brains of…
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