Description of Research Expertise

The goal of our laboratory is to understand non-calciometabolic effects of vitamin D and to exploit this understanding to design new therapeutic approaches to common diseases such as sarcopenia and obesity. Towards this goal we use large human data sets and mouse physiology combined with high throughput sequencing to drive questions in mouse models of disease and cell culture and results from unbiased screening in cell culture to drive test-of-principle experiments and trials in mice and humans. Additionally, we rely on core principles of improv (“LISTEN” (to your collagues and to the data), say “yes, and…” (if you encounter a fact that doesn’t fit your theory, follow the fact), “find the game” (what is interesting, can you set up your Qs so that any answer is interesting), “If this is true, then what else is true…” (if you find something interesting, does it imply other interesting things), “there are no mistakes” (for well designed experiments, there are no failures)) to drive our science.