Michael Aaron Silverman

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations

Contact information
3615 Civic Center Blvd
Philadelphia, PA 19104
Education:
BS (Biology)
Cornell University, 1998.
MD, PhD (Medicine and Immunology)
University of Pennsylvania School of Medicine, 2007.
Permanent link
 
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Description of Clinical Expertise

Immunocompromised patients

Description of Research Expertise

Microbiome, Immunology, HLA, MHC, antibiotics, intestinal immune system, autoimmune (type I) diabetes

Selected Publications

Silverman M, Kua L, Tanco A, Pala M, Palomba A,Tanes C, Bittenger K, Uzzau S, Benoist C, and Mathis D: Protective major histocompatibility complex allele prevents type 1 diabetes by shaping the intestinal microbiota early in ontogeny. Proceedings of the National Academy of Sciences 114(36): 9671-9676, September 2017.

Alessandro Tanca, Valeria Manghina, Cristina Fraumene, Antonio Palomba, Marcello Abbondio, Massimo Deligios, Michael Silverman, Sergio Uzzau: Metaproteogenomics reveals taxonomic and functional changes between cecal and fecal microbiota in mouse. Frontiers in Microbiology 8(391), March 2017.

Michael A Silverman, Liza Konnikova, Jeffrey Gerber: Impact of antibiotics on necrotizing enterocolitis and antibiotic-associated diarrhea. Gastroenterology Clinics of North America 46(1): 61-76, March 2017.

Dixit A, Alexandrescu S, Boyer D, Graf, EH, Vargas SO, Silverman M: Mycoplasma hominis empyema in an 18 year-old stem cell and lung transplant recipient: Case report and review of the literature. J Pediatric Infect Dis Soc Page: in press, 2017.

Silverman MA, Misasi J, Smole S, Feldman HA, Cohan AB, Santagata S, McManus M, Ahmed AA: Pediatric Eastern Equine encephalitis in Massachussettes and New Hampshire, 1970-2010. Emerging Infectious Diseases 19(2): 194-201, Feb 2013.

Kambayashi T, Larosa DF, Silverman MA, Koretzky GA: Cooperation of adapter molecules in proximal signaling cascades during allergic inflammation. Immunol Rev 232(1): 99-114, Nov 2009.

Michael Aaron Silverman: "SLP-76: Complex regulation of FcepsilonRI signaling in mast cells" Dissertations available from ProQuest. (eds.). January 2007 Notes: Paper AAI3260992. 
http://repository.upenn.edu/dissertations/AAI3260992.

Olenchock BA, Guo R, Silverman MA, Wu JN, Carpenter JH, Koretzky GA, Zhong XP.: Impaired degranulation but enhanced cytokine production after FcepsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells. J Exp Med 205(5), May 2006.

Silverman MA, Shoag J, Wu J, Koretzky GA: Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcepsilonRI signaling in mast cells. Mol Cell Biol 26(5): 1826-38, 2006.

Koretzky GA, Abtahian F, Silverman MA.: SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond. Nat Rev Immunol 6(1): 67-78, 2006.

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Last updated: 10/05/2017
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