Perelman School of Medicine at the University of Pennsylvania

Penn Institute for Immunology

John R. Stanley

faculty photo
Emeritus Professor of Dermatology
Department: Dermatology

Contact information
University of Pennsylvania School of Medicine
Department of Dermatology
421 Curie Boulevard
Philadelphia, PA 19104
B.A. (Physics)
Cornell University, 1970.
Harvard Medical School, 1974.
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Selected Publications

Chen J, Zheng Q, Hammers CM, Ellebrecht CT, Mukherjee EM, Tang HY, Lin C, Yuan H, Pan M, Langenhan J, Komorowski L, Siegel DL, Payne AS, Stanley JR: Proteomic analysis of pemphigus autoantibodies indicates a larger, more diverse, and more dynamic repertoire than determined by B-cell genetics. Cell Reports 18: 237-247, 2017.

Yoshida K, Ishii K, Shimizu A, Yokouchi M, Amagai M, Shiraishi K, Shirakata Y, Stanley JR, Ishiko A: Non-pathogenic pemphigus foliaceus (PF) IgG acts synergistically with a directly pathogenic PF IgG to increase blistering by p38MAPK-dependent desmoglein 1 clustering. J Dermatol Sci 85: 197-207, 2017.

Hammers CM, Stanley JR: Mechanisms of Disease: Pemphigus and bullous pemphigoid. Annual Review of Pathology: Mechanisms of Disease 11: 175-197, 2016.

Hammers CM, Chen J, Lin C, Kacir S, Siegel DL, Payne AS, Stanley JR: Persistence of anti-desmoglein 3 IgG B-cell clones in pemphigus patients over years. J. Invest. Dermatol. 135: 742-749, 2015.

Toumi A, Saleh MA, Yamagami J, Abida O, Kallel M, Masmoudi A, Makni S, Turki H, Hachiya T, Kuroda K, Stanley JR, Masmoudi H, Amagai M: Autoimmune reactivity against precursor form of desmoglein 1 in healthy Tunisians in the area of endemic pemphigus foliaceus. J Dermatol Sci doi: 10.1016/j.jdermsci.2013.02.002. Epub 2012 Feb 19, 70(1): 19-25 April 2013.

Kouno K, Lin C, Schechter N, Siegel D, Yang X, Seykora JT, Stanley JR: Targeted delivery of tumor necrosis factor-related apoptosis-inducing ligand to keratinocytes with a pemphigus monoclonal antibody. J Invest Dermatol February 2013 Notes: Advance online publication 4 April 2013; doi: 10.1038/jid.2013.85.

Hammers CM, Stanley JR: Antibody phage display: Technique and applications J. Invest. Dermatol. 134:e17(doi:10.1038/jid 2013.521), 2013.

Hammers CM, Stanley JR: Desmoglein-1, differentiation, and disease. J. Clin. Invest. Doi:10.1172/JCI69071, 2013.

Lunardon L, Tsai KJ, Propert KJ, Fett N, Stanley JR, Werth VP, Tsai DE, Payne AS: Adjuvant rituximab therapy of pemphigus: A single center experience with 31 patients. Arch Dermatol 148: 1031-1036, 2012.

Yamagami J, Payne AS, Kacir S, Ishii K, Siegel DL, Stanley JR: Homologous regions of heavy chain complementarity determining region 3 (H-CDR3) of pemphigus antibodies cause pathogenicity. J Clin Invest 120: 4111-4117, 2010.

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Last updated: 07/12/2017
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