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Perelman School of Medicine at the University of Pennsylvania Advanced Search

Richard J. Schwab, MD

Richard J. Schwab, MD

faculty photo
Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
University of Pennsylvania Medical Center
3624 Market Street, Suite 205
Philadelphia, PA 19104
Office: (215) 662-7772
Fax: (215) 615-4874
Education:
B.A.
Haverford College, 1979.
M.D. (Medicine)
University of Pennsylvania, 1983.
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Description of Research Expertise

Dr. Schwab’s research has focused on the pathogenesis of obstructive sleep apnea utilizing novel upper airway imaging techniques. His studies help elucidate the role of the motion of key structures of the upper airway in mediating airway closure. By examining dynamic state-related changes in the upper airway and soft tissue structures surrounding the upper airway he has begun to understand the biomechanics of apneic events. He has studied patients with both magnetic resonance imaging and electronic beam computed tomography during wakefulness and sleep. Several novel findings have resulted from these studies: 1) the anatomic significance of the lateral pharyngeal walls in mediating airway caliber in normals and apneics; and 2) the characterization of the changes in upper airway caliber during the respiratory cycle and the importance of end-expiratory airway narrowing. Dr. Schwab collaborates closely with members of the Departments of Radiology and Biomechanical and Computer Engineering. They have developed state-of-the-art, computer graphics-based analysis software to help model in three dimensions the biomechanical interrelationships between the soft tissue structures and the upper airway.

Selected Publications

Kim, A, Keenan, BT, Jackson, N, Chan, EL, Staley, B, Poptani, H, Torigian, DA, Pack, AI, Schwab, RJ : Tongue Fat and its Relationship to Obstructive Sleep Apnea. SLEEP 37(6), June 2014, in press.

Keenan BT, Maislin G, Sunwoo BY, Arnardottir ES, Jackson N, Olafsson I, Juliusson S, Scwab RJ, Gislason T, Benedikstdottir B, Pack AI: Obstructive Sleep Apnea Treatment and Fasting Lipids: A Comparative Effectiveness Study. Eur Respir J May 2014, in press.

Chi, L, Comyn, FL, Keenan, BT, Cater, J, Maislin, G, Pack, AI, Schwab, RJ: Heritability of Craniofacial Structures in Normal Subjects and Patients with Sleep Apnea. SLEEP 2014, in press.

Schwab, RJ, Kim, C, Siegel, LC, Keenan, BT, Black, J, Farid-Moayer, M, Podmore, JL, Vaska, M: Examining the Mechanism of Action of a New Device Using Oral Pressure Therapy for the Treatment of Obstructive Sleep Apnea. SLEEP 37(7): 1237-1247, July 2014.

Brennick, M, Delikatny, J, Pack, AI, Pickup, S, Shinde, S, Zhu, J, Roscoe, I, Kim, DY, Buxbaum, LU, Cater, JR, Schwab, RJ : Tongue Fat Infiltration in Obese vs. Lean Zucker Rats. SLEEP 37(6), June 2014.

Kim, AM, Keenan, BT, Jackson, N, Chan, EL, Staley, B, Torigian, DA, Alavi, A, Schwab, RJ: Metabolic Activity of the Tongue in Obstructive Sleep Apnea. A Novel Application of FDG Positron Emission Tomography Imaging. Am J Respir Crit Care Med 189(11): 1416-1425, June 2014.

Senapati S, Gracia CR, Freeman EW, Sammel MD, Lin H, Kim C, Schwab RJ, Pien GW: Hormone variations associated with quantitative fat measures in the menopausal transition. Climacteric 17(2): 183-90, April 2014.

Pien GW, Pack AI, Jackson N, Maislin G, Macones GA, Schwab RJ: Risk factors for sleep-disordered breathing in pregnancy. Thorax 69(4): 371-377, 2014.

Sutherland, K, Schwab, RJ, Maislin, G, Lee, RWW, Benedikstdsottir, B, Pack, AI, Gislason, T, Juliusson, S, Cistulli, PA: Facial Phenotyping by Quantitative Photography Reflects Craniofacial Morphology Measured on MRI in Icelandic Sleep Apnea Patients. SLEEP 37(5): 959-68, 2014.

Koren D, Marcus CL, Kim C, Gallagher PR, Schwab R, Bradford RM, Zemel BS: Anthropometric predictors of visceral adiposity in normal-weight and obese adolescents. Pediatr Diabetes 14(8): 575-84, December 2013.

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Last updated: 07/10/2014
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