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R. Nick Bryan, M.D., Ph.D

R. Nick Bryan, M.D., Ph.D

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Emeritus Professor of Radiology
Department: Radiology

Contact information
Department of Radiology
Perelman School of Medicine
University of Pennsylvania Health System
3600 Market Street, Suite 370
Philadelphia, PA 19104-4283
Office: 215-662-3660
Fax: 215-615-3681
M.D. (Medicine)
University of Texas Medical Branch, Galveston, Texas, 1969.
Ph.D. (Anatomy)
University of Texas Medical Branch, Galveston, TX, 1973.
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Description of Research Expertise

Cerebral MRI findings and cognitive functioning; applications of perfusion MRI for neurological studies; development of spatially-oriented databases for digital brain images; nuclear magnetic resonance evaluation of stroke; physiologic imaging of human brain tumors.

Description of Clinical Expertise


Selected Publications

Rapp SR, Espeland ME, Manson JE, Resnick SM, Bryan NR, Smoller S, Coker LH, Phillips LS, Stefanick ML, and Sarto GE for the Women’s Health Initiative Memory Study.: Educational attainment, MRI changes and cognitive function in older postmenopausal women from the Women’s Health Initiative Memory Study. International J Psychiatry in Medicine 46(2): 119-141, 2014.

Mark D. Sullivan, MD, PhD;Wayne J. Katon, MD; Laura C. Lovato, MA; Michael E. Miller, PhD; Anne M. Murray, MD; Karen R. Horowitz, MD; R. Nick Bryan, MD; Hertzel C. Gerstein, MD; Santica Marcovina, MD; Basil E. Akpunonu, MD; Janice Johnson, BA; Jean Francois Yale, MD; Jeff Williamson, MD; Lenore J. Launer, PhD: Association of Depression With Accelerated Cognitive Decline Among Patients With Type 2 Diabetes in the ACCORD-MIND Trial. JAMA Psychiatry 70(10): 1041-1047, October 2013.

Laura H Coker, Mark A Espeland, Patricia E Hogan, Susan M Resnick, R Nick Bryan, Jennifer G Robinson, Joseph S Goveas, Christos Davatzikos, Lewis H Kuller, Jeff D Williamson, Cheryl D Bushnell, and Sally A Shumaker : Change in Brain and Lesion Volumes Following CEE Therapies: The WHIMS MRI Studies NEUROLOGY September 2013.

A statement about authorship from individual members of the International Society for Strategic Studies in Radiology (IS3R). European radiology 23(1): 1-2, Jan 2013.

Espeland Mark A, Bryan R Nick, Goveas Joseph S, Robinson Jennifer G, Siddiqui Mustafa S, Liu Simin, Hogan Patricia E, Casanova Ramon, Coker Laura H, Yaffe Kristine, Masaki Kamal, Rossom Rebecca, Resnick Susan M: Influence of type 2 diabetes on brain volumes and changes in brain volumes: results from the Women's Health Initiative Magnetic Resonance Imaging studies. Diabetes care 36(1): 90-7, Jan 2013.

Na Zhu, David R Jacobs, Pamela J Schreiner, Kristine Yaffe, R Nick Bryan, Lenore J Launer, Rachel A Whitmer, Stephen Sidney, Ellen Demerath, William Thomas, Claude Bouchard, Ka He, Jared Reis, and Barbara Sternfeld: Cardiorespiratory Fitness and Cognitive function in Middle-Age: The CARDIA Study. NEUROLOGY 539072, 2013.

Hendee William, Bosma Jennifer L, Bresolin Linda B, Berlin Leonard, Bryan R Nick, Gunderman Richard B: Web modules on professionalism and ethics. Journal of the American College of Radiology: JACR 9(3): 170-3, Mar 2012.

Espeland MA, Bryan RN, Casanova R, Coker LH, Goveas JS, Hogan PE, Liu S, Masaki K, Resnick SM, Robinson J, Rossom R, Siddiqui MS, Yaffe K.: Influence of type 2 diabetes mellitus on brain volumes and changes in brain volumes. Diabetes 61S(1): A348, 2012.

Launer Lenore J, Miller Michael E, Williamson Jeff D, Lazar Ron M, Gerstein Hertzel C, Murray Anne M, Sullivan Mark, Horowitz Karen R, Ding Jingzhong, Marcovina Santica, Lovato Laura C, Lovato James, Margolis Karen L, O'Connor Patrick, Lipkin Edward W, Hirsch Joy, Coker Laura, Maldjian Joseph, Sunshine Jeffrey L, Truwit Charles, Davatzikos Christos, Bryan R Nick: Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy. Lancet neurology 10(11): 969-77, Nov 2011.

Gaonkar Bilwaj, Erus Guray, Pohl Kilian M, Tanwar Manoj, Margiewicz Stefan, Bryan R Nick, Davatzikos Christos: AUTOMATED SEGMENTATION OF CORTICAL NECROSIS USING A WAVELET BASED ABNORMALITY DETECTION SYSTEM. Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical Imaging 2011: 1391-1395, 3 2011.

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Last updated: 03/03/2014
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