John E. Biaglow, Ph.D.

faculty photo
Department: Radiation Oncology

Contact information
Philadelphia, PA 19104
Office: 2158980062
B.S. (Chemistry)
John Carroll University , 1959.
MS (Biochemistry)
Loyola University , 1961.
Ph.D. (Biochemistry)
Loyola University , 1964.
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Selected Publications

Ttttle SW, Miller, RA, Biaglow, JE: Glucose-6-phosphate dehydrogenase protects cells against PDT-induced apoptosis Photochemistry and Photobiology 2003.

Biaglow, JE, Lee, I., Donahue, J., Held, K., Mieyal, J., Dewhirst, M., and Tuttle, S. : Glutathione depletion or radiation treatment alters respiration and indues apoptosis in R323OAC Mammary carcinoma. Papst publishing Co. Germany, 2003.

Biaglow JE, Ayene, I., Koch, CJ., Donahue, J., Stomato, T., Mieyal, J, and Tuttle, SW: Radiation response during altered protein thiol redox Radiation Research 2003.

203. Lee , I., Glickson, J.D., Dewhirst, M.W., Leeper, D. Burd, A, Poptoni, H., Nadar, L, McKenna, W.G., and Biaglow, J.E.: Effect of mild hyperglycemia: Meta-Iodo-benzylguanidine on the radiation response of two solid tumors in vivo. ISSOT meeting, 1999. H. Swartz, ed (eds.). 2003.

Magda, D., Geraincscuk, Lauren, P, Miller, RM., Biaglow, J.E., and Sessler, J. : Motexaphin gadolinium reacts with ascorbate to produce reactive oxygen species Chem. Comm Page: 2739-2731, 2002.

Ayene, I, Stomato, T., TUTTLE, SW., KOCH, CJ., Biaglow, J.E.: Mutation in the glucose-6-phosphate dehydrogenase gene lerads to inactivation of Ku DNA binding during oxidative stress. J. Biol. Chem 277: 9929-35, 2002.

Willson, D., Evans, S., . and Biaglow, J. : Oxygen Measurements in the 21st Century. Kluwer Pub, N.Y, 2002.

Burd, R.,Weisber, , Biaglow, JE., Whal, M., Lee, I. Leeper, D., : Absence of Crabtree effect in human melanoma cells adapted to growth at low pH: Reversal by respiratory inhibitors. Cancer Res 14: 5630-5. 2001.

Synder, SA, Lanzen, JL, Braun, RD., Rosner, G, Secomb, TW., Biaglow, J., Brizel DM, Dewhirst MW: Simultaneous administration of glucose and hyperoxic gas achieves greater improvement of tumor oxygenation than hyperoxic gas alone. Int. J. Radiat. Oncol. Biol. Phys Page: 494-506, 2001.

Magda, D., Lepp, C., Gerasimchuck, N., Lee, I.,Sessler. J., Lin. A., Biaglow, J., Miller, R. : Redox cycling by motexaphin gadolinium enhances cellular response to radiation by forming reactive oxygen species. Int. J. Radiat., Oncol. Biol. And Phys 4: 1025-36, 2001.

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Last updated: 07/12/2006
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