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Rebecca L Ashare, Ph.D.

Rebecca L Ashare, Ph.D.

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Research Assistant Professor of Psychology in Psychiatry
Department: Psychiatry

Contact information
Center for Interdisciplinary Research on Nicotine Addiction
3535 Market St, Suite 4100
Philadelphia, PA 19104
Office: (215) 746-5789
B.A (Psychology)
State University of New York at Buffalo, 2003.
M.A (Clinical Psychology)
State University of New York at Buffalo, 2007.
Ph.D. (Clinical Psychology)
State University of New York at Buffalo, 2011.
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Description of Research Expertise

My research focuses on evaluating more effective treatments for nicotine dependence, with a specific focus on pharmacotherapies that reduce nicotine withdrawal-related cognitive deficits. Through the use of human laboratory studies my work has emphasized psychophysiological, cognitive, and stress responses related to smoking behavior. Since joining the Center for Interdisciplinary Research on Nicotine Addiction (CIRNA), we have begun research on the potential therapeutic benefits of pro-cognitive medications for nicotine dependence. Current projects are aimed at understanding how genetic factors, pre-treatment cognitive function, and neural substrates affect treatment response.

Selected Publications

Ashare Rebecca L, Schmidt Heath D: Optimizing treatments for nicotine dependence by increasing cognitive performance during withdrawal. Expert opinion on drug discovery 9(6): 579-94, Jun 2014.

Ashare Rebecca, Strasser Andrew A, Wileyto E Paul, Cuevas Jocelyn, Audrain-McGovern Janet: Cognitive deficits specific to depression-prone smokers during abstinence. Experimental and clinical psychopharmacology 22(4): 323-31, Aug 2014.

Ashare Rebecca L, Wileyto E Paul, Ruparel Kosha, Goelz Patricia M, Hopson Ryan D, Valdez Jeffrey N, Gur Ruben C, Loughead James, Lerman Caryn: Effects of tolcapone on working memory and brain activity in abstinent smokers: a proof-of-concept study. Drug and alcohol dependence 133(3): 852-6, Dec 2013.

Ashare Rebecca L, Norris Catherine J, Wileyto E Paul, Cacioppo John T, Strasser Andrew A: Individual differences in positivity offset and negativity bias: Gender-specific associations with two serotonin receptor genes. Personality and individual differences 55(5): 469-473, Sep 2013.

Ashare Rebecca L, Valdez Jeffrey N, Ruparel Kosha, Albelda Benjamin, Hopson Ryan D, Keefe John R, Loughead James, Lerman Caryn: Association of abstinence-induced alterations in working memory function and COMT genotype in smokers. Psychopharmacology 230(4): 653-62, Jul 2013.

Ashare Rebecca L, Wileyto E Paul, Perkins Kenneth A, Schnoll Robert A: The first 7 days of a quit attempt predicts relapse: validation of a measure for screening medications for nicotine dependence. Journal of addiction medicine 7(4): 249-54, Jul-Aug 2013.

Ashare Rebecca L, Falcone Mary, Lerman Caryn: Cognitive function during nicotine withdrawal: Implications for nicotine dependence treatment. Neuropharmacology 76 Pt B: 581-91, Apr 2013.

Ashare Rebecca L, Ray Riju, Lerman Caryn, Strasser Andrew A: Cognitive effects of the acetylcholinesterase inhibitor, donepezil, in healthy, non-treatment seeking smokers: A pilot feasibility study. Drug and alcohol dependence 126(1-2): 263-7, May 2012.

Ashare R L, Karlawish J H, Wileyto E P, Pinto A, Lerman C: APOE ɛ4, an Alzheimer's disease susceptibility allele, and smoking cessation. The pharmacogenomics journal 13(6): 538-43, Dec 2012.

Ashare Rebecca L, Hawk Larry W: Effects of smoking abstinence on impulsive behavior among smokers high and low in ADHD-like symptoms. Psychopharmacology 219(2): 537-47, Jan 2012.

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Last updated: 07/16/2015
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