Edward F. Attiyeh, M.D.

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Adjunct Assistant Professor of Pediatrics (Oncology)
Department: Pediatrics

Contact information
Education:
A.B. (Molecular Biology)
Princeton University, 1995.
M.D.
Albert Einstein College of Medicine, 1999.
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Selected Publications

Ambros IM, Tonini GP, Pötschger U, Gross N, Mosseri V, Beiske K, Berbegall AP, Bénard J, Bown N, Caron H, Combaret V, Couturier J, Defferrari R, Delattre O, Jeison M, Kogner P, Lunec J, Marques B, Martinsson T, Mazzocco K, Noguera R, Schleiermacher G, Valent A, Van Roy N, Villamon E, Janousek D, Pribill I, Glogova E, Attiyeh EF, Hogarty MD, Monclair TF, Holmes K, Valteau-Couanet D, Castel V, Tweddle DA, Park JR, Cohn S, Ladenstein R, Beck-Popovic M, De Bernardi B, Michon J, Pearson ADJ, Ambros PF.: Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable MYCN-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group. J Clin Oncol 38: 3685-3697, Nov 2020.

Depuydt P, Boeva V, Hocking TD, Cannoodt R, Ambros IM, Ambros PF, Asgharzadeh S, Attiyeh EF, Combaret V, Defferrari R, Fischer M, Hero B, Hogarty MD, Irwin MS, Koster J, Kreissman S, Ladenstein R, Lapouble E, Laureys G, London WB, Mazzocco K, Nakagawara A, Noguera R, Ohira M, Park JR, Pötschger U, Theissen J, Tonini GP, Valteau-Couanet D, Varesio L, Versteeg R, Speleman F, Maris JM, Schleiermacher G, De Preter K.: Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients. J Natl Cancer Inst 110: 1084-1093, Oct 2018.

Chang X, Zhao Y, Hou C, Glessner J, McDaniel L, Diamond MA, Thomas K, Li J, Wei Z, Liu Y, Guo Y, Mentch FD, Qiu H, Kim C, Evans P, Vaksman Z, Diskin SJ, Attiyeh EF, Sleiman P, Maris JM, Hakonarson H.: Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk. Nat Commun 8: 569, Sep 2017.

Vujkovic M, Attiyeh EF, Ries RE, Goodman EK, Ding Y, Kavcic M, Alonzo TA, Wang YC, Gerbing RB, Sung L, Hirsch B, Raimondi S, Gamis AS, Meshinchi S, Aplenc R.: Genomic architecture and treatment outcome in pediatric acute myeloid leukemia: a Children's Oncology Group report. Blood 129: 3051-3058, Jun 2017.

Liu Z, Lam N, Wang E, Virden RA, Pawel B, Attiyeh EF, Maris JM, Thiele CJ.: Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma. Oncogene 36: 97-109, Jan 2017.

Schnepp Robert W, Khurana Priya, Attiyeh Edward F, Raman Pichai, Chodosh Sara E, Oldridge Derek A, Gagliardi Maria E, Conkrite Karina L, Asgharzadeh Shahab, Seeger Robert C, Madison Blair B, Rustgi Anil K, Maris John M, Diskin Sharon J: A LIN28B-RAN-AURKA Signaling Network Promotes Neuroblastoma Tumorigenesis. Cancer cell 28(5): 599-609, Nov 2015.

Attiyeh Edward F, Maris John M, Lock Richard, Reynolds C Patrick, Kang Min H, Carol Hernan, Gorlick Richard, Kolb E Anders, Keir Stephen T, Wu Jianrong, Landesman Yosef, Shacham Sharon, Lyalin Dmitry, Kurmasheva Raushan T, Houghton Peter J, Smith Malcolm A: Pharmacodynamic and Genomic Markers Associated With Response to the XPO1/CRM1 Inhibitor Selinexor (KPT-330): A Report From the Pediatric Preclinical Testing Program. Pediatric blood & cancer Sep 2015.

Eleveld Thomas F, Oldridge Derek A, Bernard Virginie, Koster Jan, Daage Leo Colmet, Diskin Sharon J, Schild Linda, Bentahar Nadia Bessoltane, Bellini Angela, Chicard Mathieu, Lapouble Eve, Combaret Valérie, Legoix-Né Patricia, Michon Jean, Pugh Trevor J, Hart Lori S, Rader JulieAnn, Attiyeh Edward F, Wei Jun S, Zhang Shile, Naranjo Arlene, Gastier-Foster Julie M, Hogarty Michael D, Asgharzadeh Shahab, Smith Malcolm A, Guidry Auvil Jaime M, Watkins Thomas B K, Zwijnenburg Danny A, Ebus Marli E, van Sluis Peter, Hakkert Anne, van Wezel Esther, van der Schoot C Ellen, Westerhout Ellen M, Schulte Johannes H, Tytgat Godelieve A, Dolman M Emmy M, Janoueix-Lerosey Isabelle, Gerhard Daniela S, Caron Huib N, Delattre Olivier, Khan Javed, Versteeg Rogier, Schleiermacher Gudrun, Molenaar Jan J, Maris John M: Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations. Nature genetics 47(8): 864-71, Aug 2015.

Vujkovic Marijana, Attiyeh Edward F, Ries Rhonda E, Horn Michelle, Goodman Elizabeth K, Ding Yang, Kavcic Marko, Alonzo Todd A, Gerbing Robert B, Hirsch Betsy, Raimondi Susana, Gamis Alan S, Meshinchi Soheil, Aplenc Richard: Concordance of copy number alterations using a common analytic pipeline for genome-wide analysis of Illumina and Affymetrix genotyping data: a report from the Children's Oncology Group. Cancer genetics 208(7-8): 408-13, Jul-Aug 2015.

Mandriota Stefano J, Valentijn Linda J, Lesne Laurence, Betts David R, Marino Denis, Boudal-Khoshbeen Mary, London Wendy B, Rougemont Anne-Laure, Attiyeh Edward F, Maris John M, Hogarty Michael D, Koster Jan, Molenaar Jan J, Versteeg Rogier, Ansari Marc, Gumy-Pause Fabienne: Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism. Oncotarget 6(21): 18558-76, Jul 2015.

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Last updated: 08/04/2021
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