Edward F. Attiyeh, M.D.
Edward F. Attiyeh, M.D.
Assistant Professor of Pediatrics
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
3501 Civic Center Blvd., CTRB 3050
Philadelphia, PA 19104
3501 Civic Center Blvd., CTRB 3050
Philadelphia, PA 19104
Office: (267) 426-5534
Fax: (267) 426-0685
Fax: (267) 426-0685
Email:
attiyeh@email.chop.edu
attiyeh@email.chop.edu
Education:
A.B. (Molecular Biology)
Princeton University, 1995.
M.D.
Albert Einstein College of Medicine, 1999.
Permanent linkA.B. (Molecular Biology)
Princeton University, 1995.
M.D.
Albert Einstein College of Medicine, 1999.
Selected Publications
Nguyễn Lễ B, Diskin Sharon J, Capasso Mario, Wang Kai, Diamond Maura A, Glessner Joseph, Kim Cecilia, Attiyeh Edward F, Mosse Yael P, Cole Kristina, Iolascon Achille, Devoto Marcella, Hakonarson Hakon, Li Hongzhe K, Maris John M: Phenotype Restricted Genome-Wide Association Study Using a Gene-Centric Approach Identifies Three Low-Risk Neuroblastoma Susceptibility Loci. PLoS genetics 7(3): e1002026, Mar 2011.Cole Kristina A, Huggins Jonathan, Laquaglia Michael, Hulderman Chase E, Russell Mike R, Bosse Kristopher, Diskin Sharon J, Attiyeh Edward F, Sennett Rachel, Norris Geoffrey, Laudenslager Marci, Wood Andrew C, Mayes Patrick A, Jagannathan Jayanti, Winter Cynthia, Mosse Yael P, Maris John M: RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America 108(8): 3336-41, Feb 2011.
Wang Kai, Diskin Sharon J, Zhang Haitao, Attiyeh Edward F, Winter Cynthia, Hou Cuiping, Schnepp Robert W, Diamond Maura, Bosse Kristopher, Mayes Patrick A, Glessner Joseph, Kim Cecilia, Frackelton Edward, Garris Maria, Wang Qun, Glaberson Wendy, Chiavacci Rosetta, Nguyen Le, Jagannathan Jayanti, Saeki Norihisa, Sasaki Hiroki, Grant Struan F A, Iolascon Achille, Mosse Yael P, Cole Kristina A, Li Hongzhe, Devoto Marcella, McGrady Patrick W, London Wendy B, Capasso Mario, Rahman Nazneen, Hakonarson Hakon, Maris John M: Integrative genomics identifies LMO1 as a neuroblastoma oncogene. Nature 469(7329): 216-20, Jan 2011.
Diskin SJ, Hou C, Glessner JT, Attiyeh EF, Laudenslager M, Bosse K, Cole K, Mossé YP, Wood A, Lynch JE, Pecor K, Diamond M, Winter C, Wang K, Kim C, Geiger EA, McGrady PW, Blakemore AIF, London WB, Shaikh TH, Bradfield J, Grant SFA, Li H, Devoto M, Rappaport ER, Hakonarson H, and Maris John M: Copy number variation at 1q21.1 associated with neuroblastoma. Nature 459(7249): 987-91, Jun 2009.
Capasso M, Devoto M, Hou C, Asgharzadeh S, Glessner JT, Attiyeh EF, Mosse YP, Kim C, Diskin SJ, Cole KA, Bosse K, Diamond M, Laudenslager M, Winter C, Bradfield JP, Scott RH, Jagannathan J, Garris M, McConville C, London WB, Seeger RC, Grant SF, Li H, Rahman N, Rappaport E, Hakonarson H, Maris JM: Common variations in BARD1 influence susceptibility to high-risk neuroblastoma. Nature genetics 41(6): 718-723, Jun 2009.
Volchenboum SL, Li C, Li S, Attiyeh EF, Reynolds C P, Maris JM, Look AT, and George RE: Comparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide single nucleotide polymorphism array analysis. Cancer research 69(10): 4143-9, May 2009.
Teachey DT, Greiner R, Seif A, Attiyeh EF, Bleesing J, Choi J, Manno C, Rappaport E, Schwabe D, Sheen C, Sullivan KE, Zhuang H, Wechsler DS, and Grupp SA: Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome. British Journal of Haematology 145(1): 101-6, Apr 2009.
Attiyeh EF, Diskin SJ, Attiyeh MA, Mossé YP, Hou C, Jackson EM, Kim C, Glessner J, Hakonarson H, Biegel JA, and Maris JM: Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy. Genome research 19(2): 276-83, Feb 2009.
Park JR, Villablanca JG, London WB, Gerbing RB, Haas-Kogan D, Adkins ES, Attiyeh EF, Maris JM, Seeger RC, Reynolds CP, Matthay KK: Outcome of high-risk stage 3 neuroblastoma with myeloablative therapy and 13-cis-retinoic acid: A report from the Children's Oncology Group. Pediatr Blood Cancer 52(1): 44-50, 2009.
Maris JM, Mosse YP, Bradfield JP, Hou C, Monni S, Scott RH, Asgharzadeh S, Attiyeh EF, Diskin SJ, Laudenslager M, Winter C, Cole KA, Glessner JT, Kim C, Frackelton EC, Casalunovo T, Eckert AW, Capasso M, Rappaport EF, McConville C, London WB, Seeger RC, Rahman N, Devoto M, Grant SF, Li H, Hakonarson H: Chromosome 6p22 locus associated with clinically aggressive neuroblastoma. N Engl J Med 358(24): 2585-93, 2008.