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Rebecca N. Ichord, MD

Rebecca N. Ichord, MD

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Associate Professor of Neurology at the Children's Hospital of Philadelphia
Department: Neurology

Contact information
Dept. of Neurology
Children’s Hospital of Philadelphia
3400 Civic Center Blvd., 6th Floor
Philadelphia, PA 19104-4318
Office: 215-590-4142
Fax: 215-590-5120
B.S. (Biology, Magna cum laude)
University of Hawaii , 1975.
George Washington University School of Medicine (with distinction), 1979.
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Description of Research Expertise

Clinical research is focused primarily on stroke in childhood, including arterial ischemic stroke, intracranial hemorrhage, cerebral venous thrombosis, and related cerebral vascular disorders. Current active research activities include an NIH-funded multicenter cohort study to evaluate safety/dose-finding for thrombolysis in pediatric stroke (TIPS); vascular effects of infection in pediatric stroke (VIPS); inflammatory coagulation markers in pediatric stroke; neurological manifestations of cerebral ischemic injury in sickle cell anemia (SITT and SWiTCH trials); a two-center cohort study of outcome predictors in childhood spontaneous intracranial hemorrhage; and a pilot study of treadmill training therapy in children recovering from stroke.

Related research activities through collaborations locally at CHOP/Penn and nationally include: hypothermia for pediatric cardiac arrest, and mechanisms of secondary injury in traumatic brain injury in children.

Description of Clinical Expertise

Childhood Stroke & acute brain injury due to cardiac arrest and traumatic brain injury. Primary clinical focus is stroke. As director of the CHOP Stroke Program, I oversee operation of clinical stroke care programs through a 24/7 rapid response neurovascular consultation service and multidisciplinary out-patient stroke follow-up clinic. The Stroke Program team includes expert care in neonatal stroke and cognitive effects of stroke by Dr. Lori Billinghurst, and effects of congenital heart disease on developing brain by Dr. Daniel Licht. Training elements include bedside & didactic teaching activities for physician and nursing staff within CHOP, and community outreach via a CME program for primary ED & pediatric practitioners. A pediatric stroke fellowship was established in July 2008.

Selected Publications

Williams RP, Banwell B, Berg RA, Dlugos DJ, Donnelly M, Ichord R, Kessler SK, Lavelle J, Massey SL, Hewlett J, Parker A, Topjian A, Abend NS : Impact of an ICU EEG Monitoring Pathway on Timeliness of Therapeutic Intervention and Electrographic Seizure Termination. Epilepsia 2016 Notes: in press.

Smith DM, Vossough A, Vorona GA, Beslow LA, Ichord RN, Licht DJ : Pediatric cavernous sinus thrombosis: A case series and review of the literature. Neurology 85(9): 763-9, Sept 2015.

Topjian AA, Fry M, Jawad AF, Herman ST, Nadkarni VM, Ichord R, Berg RA, Dlugos DJ, Abend NS: Detection of Electrographic Seizures by Critical Care Providers Using Color Density Spectral Array After Cardiac Arrest is Feasbile. Pediatr Crit Care Med. (eds.). 16(5): 461-7, Jun 2015.

Sultan SM, Beslow LA, Vossough A, Elkind MS, Kasner SE, Mirsky DM, Licht DJ, Ichord RN: Predictive validity of severity grading for cerebral steno-occlusive arteriopathy in recurrent childhood ischemic stroke. Int J Stroke 10(2): 213-8, Feb 2015 Notes: Epub 2014 Aug 8.

Baird Lissa C, Smith Edward R, Ichord Rebecca, Piccoli David A, Bernard Timothy J, Spinner Nancy B, Scott R Michael, Kamath Binita M: Moyamoya Syndrome Associated with Alagille Syndrome: Outcome after Surgical Revascularization. The Journal of pediatrics 166(2): 470-3, Feb 2015.

Plumb Patricia, Seiber Eric, Dowling Michael M, Lee JoEllen, Bernard Timothy J, deVeber Gabrielle, Ichord Rebecca N, Bastian Rachel, Lo Warren D: Out-of-Pocket Costs for Childhood Stroke: The Impact of Chronic Illness on Parents' Pocketbooks. Pediatric neurology 52(1): 73-76.e2, Jan 2015.

Nabavizadeh SA, Vossough A, Ichord RN, Kwaitkowski J, Pukenas BA, Smith MJ, Storm PB, Zager EL, Hurst RW: Intracranial Aneurysms in Sickle-Cell Anemia: Clinical and Imaging Findings. J NeuroInterventional Surg in press 2015.

Wintermark M, Hills NK, DeVeber GA, James Barkovich AJ, Elkind MSV, Sear K, Zhu G, MD, Leiva-Salinas C, Hou Q, Dowling MM, Bernard TJ, Friedman NR, Ichord RN, Fullerton HJ, and the VIPS Investigators : Arteriopathy Diagnosis in Childhood Arterial Ischemic Stroke: Results of the VIPS Study. Stroke 45(12): 3597-605, Dec 2014.

11. Bernard TJ, Rivkin MJ, Scholz K, deVeber G, Kirton A, Gill JC, Chan AK, Hovinga CA, Ichord RN, Grotta J, Jordan LC, Benedict S, Friedman NR, Dowling MM, Elbers J, Torres M, Sultan S, Cummings D, Grabowski EF, McMillan H, Beslow L, Amlie-Lefond C : Emergence of the Primary Pediatric Stroke Center: impact of the Thrombolysis in Pediatric Stroke (TIPS) Trial. Stroke 45(7): 2018-23, July 2014.

Dowling MM, Noetzel MJ, Rodeghier MJ, Quinn CT, Hirtz DG, Ichord RN, Kwiatkowski JL, Roach ES, Kirkham FJ, Casella JF, DeBaun MR. : Headache and Migraine in Children with Sickle Cell Disease are Associated with Lower Hemoglobin and Higher Pain Event Rates but not Silent Cerebral Infarction. J Pediatrics 164(5): 1175-1180, May 2014.

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Last updated: 04/20/2016
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