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Rebecca N. Ichord, MD

Rebecca N. Ichord, MD

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Associate Professor of Neurology at the Children's Hospital of Philadelphia
Department: Neurology

Contact information
Dept. of Neurology
Children’s Hospital of Philadelphia
CTRB 10th Floor
3501 Civic Ctr Blvd
Philadelphia, PA 19104-4318
Office: 215-590-4142
Fax: 215-590-5120
Education:
B.S. (Biology, Magna cum laude)
University of Hawaii , 1975.
M.D.
(year 1-2), New York Medical College, 1977.
MD
(year 3-4) George Washington University School of Medicine (with distinction), 1979.
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Description of Research Expertise

Clinical research is focused primarily on stroke in childhood, including arterial ischemic stroke, intracranial hemorrhage, cerebral venous thrombosis, and related cerebral vascular disorders. Current active research activities include an NIH-funded multicenter cohort study to evaluate safety/dose-finding for thrombolysis in pediatric stroke (TIPS); vascular effects of infection in pediatric stroke (VIPS); inflammatory coagulation markers in pediatric stroke; neurological manifestations of cerebral ischemic injury in sickle cell anemia (SITT and SWiTCH trials); a two-center cohort study of outcome predictors in childhood spontaneous intracranial hemorrhage; and a pilot study of treadmill training therapy in children recovering from stroke.

Related research activities through collaborations locally at CHOP/Penn and nationally include: hypothermia for pediatric cardiac arrest, and mechanisms of secondary injury in traumatic brain injury in children.

Description of Clinical Expertise

Childhood Stroke & acute brain injury due to cardiac arrest and traumatic brain injury. Primary clinical focus is stroke. As director of the CHOP Stroke Program, I oversee operation of clinical stroke care programs through a 24/7 rapid response neurovascular consultation service and multidisciplinary out-patient stroke follow-up clinic. The Stroke Program team includes expert care in neonatal stroke and cognitive effects of stroke by Dr. Lori Billinghurst, and effects of congenital heart disease on developing brain by Dr. Daniel Licht. Training elements include bedside & didactic teaching activities for physician and nursing staff within CHOP, and community outreach via a CME program for primary ED & pediatric practitioners. A pediatric stroke fellowship was established in July 2008.

Selected Publications

Plumb Patricia, Seiber Eric, Dowling Michael M, Lee JoEllen, Bernard Timothy J, deVeber Gabrielle, Ichord Rebecca N, Bastian Rachel, Lo Warren D: Out-of-Pocket Costs for Childhood Stroke: The Impact of Chronic Illness on Parents' Pocketbooks. Pediatric neurology 52(1): 73-76.e2, Jan 2015.

Baird Lissa C, Smith Edward R, Ichord Rebecca, Piccoli David A, Bernard Timothy J, Spinner Nancy B, Scott R Michael, Kamath Binita M: Moyamoya Syndrome Associated with Alagille Syndrome: Outcome after Surgical Revascularization. The Journal of pediatrics Oct 2014.

Sultan SM, Beslow LA, Vossough A, Elkind MS, Kasner SE, Mirsky DM, Licht DJ, Ichord RN: Predictive validity of severity grading for cerebral steno-occlusive arteriopathy in recurrent childhood ischemic stroke. Int J Stroke Aug 2014.

Ichord Rebecca N: Adult stroke risk after growth hormone treatment in childhood: first do no harm. Neurology 83(9): 776-7, Aug 2014.

Dowling MM, Noetzel MJ, Rodeghier MJ, Quinn CT, Hirtz DG, Ichord RN, Kwiatkowski JL, Roach ES, Kirkham FJ, Casella JF, DeBaun MR. : Headache and Migraine in Children with Sickle Cell Disease are Associated with Lower Hemoglobin and Higher Pain Event Rates but not Silent Cerebral Infarction. J Pediatrics 164(5): 1175-1180, May 2014.

Rhee E, Hurst R, Pukenas B, Ichord R, Cahill AM, Rossano J, Fuller S, Lin K: Mechanical embolectomy for ischemic stroke in a pediatric ventricular assist device patient. Ped Transplant 18(3): E88-92, May 2014.

Arkuszewski M, Krejza J, Chen R, Ichord R, Kwiatkowski JL, Bilello M, Zimmerman R, Ohene-Frempong K, Melhem ER: Sickle cell anemia: Intracranial stenosis and silent cerebral infarcts in children with low risk of stroke. Adv Med Sci 59(1): 108-13, Mar 2014.

Gaballah M, Storm PB, Rabinowitz D, Ichord R, Krishnamurthy G, Keller MS, McIntosh A, Hurst R, Cahill: Intra-operative Cerebral Angiography in AVM Resection in the Pediatric Population: A single institutional experience. AM J Neurosurg:Pediatrics 13(2): 222-228, Feb 2014.

King AA, Strouse JJ, Rodeghier MJ, Compas BE, Casella JF, McKinstry RC, Noetzel MJ, Quinn CT, Ichord R, Dowling MM, Miller JP, DeBaun MR: Parent education and biologic factors influence on cognition in sickle cell anemia. Am J Hematology 89(2): 162-7, Feb 2014.

Beslow LA, Ichord RN, Gindville MC, Kleinman JT, Bastian RA, Smith SE, Licht DJ, Hillis AE, Jordan LC : Hematoma Expansion is Common after Spontaneous Intracerebral Hemorrhage in Children. JAMA Neurology 71(2): 165-71, Feb 2014.

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Last updated: 01/14/2015
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