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Samuel G. Jacobson, MD, PhD

Samuel G. Jacobson, MD, PhD

faculty photo
Professor of Ophthalmology
Department: Ophthalmology

Contact information
Scheie Eye Institute
51 North 39th Street
2689
Philadelphia, PA 19104
Education:
B.A. (Humanities)
University of Illinois, 1966.
M.D. (Medicine)
University of Illinois, 1970.
Ph.D. (Psychophysics)
University of London, 1977.
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Selected Publications

Jin Minghao, Li Songhua, Hu Jane, Jin Heather H, Jacobson Samuel G, Bok Dean: Functional Rescue of Retinal Degeneration-Associated Mutant RPE65 Proteins. Advances in experimental medicine and biology 854: 525-32, 2016.

Jacobson Samuel G, Cideciyan Artur V, Huang Wei Chieh, Sumaroka Alexander, Nam Hyun Ju, Sheplock Rebecca, Schwartz Sharon B: Leber Congenital Amaurosis: Genotypes and Retinal Structure Phenotypes. Advances in experimental medicine and biology 854: 169-75, 2016.

Beltran William A, Cideciyan Artur V, Iwabe Simone, Swider Malgorzata, Kosyk Mychajlo S, McDaid Kendra, Martynyuk Inna, Ying Gui-Shuang, Shaffer James, Deng Wen-Tao, Boye Sanford L, Lewin Alfred S, Hauswirth William W, Jacobson Samuel G, Aguirre Gustavo D: Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of disease. Proceedings of the National Academy of Sciences of the United States of America 112(43): E5844-53, Oct 2015.

Matsui Rodrigo, Cideciyan Artur V, Schwartz Sharon B, Sumaroka Alexander, Roman Alejandro J, Swider Malgorzata, Huang Wei Chieh, Sheplock Rebecca, Jacobson Samuel G: Molecular Heterogeneity Within the Clinical Diagnosis of Pericentral Retinal Degeneration. Investigative ophthalmology & visual science 56(10): 6007-18, Sep 2015.

Cideciyan Artur V, Swider Malgorzata, Schwartz Sharon B, Stone Edwin M, Jacobson Samuel G: Predicting Progression of ABCA4-Associated Retinal Degenerations Based on Longitudinal Measurements of the Leading Disease Front. Investigative ophthalmology & visual science 56(10): 5946-55, Sep 2015.

Zhang Ning, Tsybovsky Yaroslav, Kolesnikov Alexander V, Rozanowska Malgorzata, Swider Malgorzata, Schwartz Sharon B, Stone Edwin M, Palczewska Grazyna, Maeda Akiko, Kefalov Vladimir J, Jacobson Samuel G, Cideciyan Artur V, Palczewski Krzysztof: Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations. Human molecular genetics 24(11): 3220-37, Jun 2015.

Jacobson Samuel G, Cideciyan Artur V, Aguirre Gustavo D, Roman Alejandro J, Sumaroka Alexander, Hauswirth William W, Palczewski Krzysztof: Improvement in vision: a new goal for treatment of hereditary retinal degenerations. Expert opinion on orphan drugs 3(5): 563-575, May 2015.

Zelinger Lina, Cideciyan Artur V, Kohl Susanne, Schwartz Sharon B, Rosenmann Ada, Eli Dalia, Sumaroka Alexander, Roman Alejandro J, Luo Xunda, Brown Cassondra, Rosin Boris, Blumenfeld Anat, Wissinger Bernd, Jacobson Samuel G, Banin Eyal, Sharon Dror: Genetics and Disease Expression in the CNGA3 Form of Achromatopsia: Steps on the Path to Gene Therapy. Ophthalmology 122(5): 997-1007, May 2015.

Cideciyan Artur V, Swider Malgorzata, Jacobson Samuel G: Autofluorescence imaging with near-infrared excitation:normalization by reflectance to reduce signal from choroidal fluorophores. Investigative ophthalmology & visual science 56(5): 3393-406, May 2015.

Jacobson Samuel G, Cideciyan Artur V, Roman Alejandro J, Sumaroka Alexander, Schwartz Sharon B, Heon Elise, Hauswirth William W: Improvement and decline in vision with gene therapy in childhood blindness. The New England journal of medicine 372(20): 1920-6, May 2015.

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Last updated: 12/07/2015
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