Kathleen M. Loomes, MD
Professor of Pediatrics (Gastroenterology, Hepatology and Nutrition) at the Children's Hospital of Philadelphia
Attending Physician, The Children's Hospital of Philadelphia
Attending Physician, Consultant in Pediatric Gastroenterology, Hospital of the University of Pennsylvania
Attending Physician, Consultant in Pediatric Gastroenterology, Pennsylvania Hospital, Philadelphia, PA
Director, Fred and Suzanne Biesecker Pediatric Liver Center, The Children's Hospital of Philadelphia
Section Chief of Research, Division of Pediatric Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia
Associate Research Director, Division of Gastroenterology, Hepatology and Nutrition Fellowship Program
Department: Pediatrics
Contact information
The Children's Hospital of Philadelphia
Division of Gastroenterology, Hepatology and Nutrition, 7th floor
34th and Civic Center Blvd.
Philadelphia, PA 19104
Division of Gastroenterology, Hepatology and Nutrition, 7th floor
34th and Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-426-7223
Fax: 267-426-7814
Fax: 267-426-7814
Email:
loomes@chop.edu
loomes@chop.edu
Education:
B.A. (Biology)
Rice University (Cum laude), 1988.
M.D. (Medicine)
University of Texas Southwestern Medical School, 1992.
Permanent linkB.A. (Biology)
Rice University (Cum laude), 1988.
M.D. (Medicine)
University of Texas Southwestern Medical School, 1992.
Selected Publications
Kennedy KV, Fawad JA, Neugut YD, Valenzuela-Araujo D, Coe A, Bhatti TR, Acord M, Manfredi MD, Mamula P, Loomes KM, Brownell JN.: SPNing our wheels-Pancreatic solid pseudopapillary neoplasm as an extraluminal etiology of persistent duodenal ulceration. JPGN Rep 6: 189-192, Feb 2025.Bennett AD, Morales KH, Huang YV, Tam V, Shah A, Loomes KM, Serper M, Bittermann T.: Lower Child Opportunity Index is associated with increased health care utilization following pediatric liver transplantation. Liver Transpl Feb 2025.
Taylor SA, Harpavat S, Gromer KD, Andreev V, Loomes KM, Bezerra JA, Jarasvaraparn C, Wang K, Horslen S, Rosenthal P, Teckman J, Valentino PL, Ng VL, Karpen SJ, Sokol RJ, Alonso EM, Mack CL; Childhood Liver Disease Research Network (ChiLDReN).: Increased serum GM-CSF at diagnosis of biliary atresia is associated with improved biliary drainage. Pediatr Res Jan 2025.
Alqahtani SA, Shpoliansky M, Vandriel SM, Johara F, Quammie C, Lurz E, Alonso EM, Daniel JF, Venkat VL, Leung DH, Economides J, Hsu EK, Loomes KM, Gupta NA, Mannino D, Menendez J, Ng VL, Kamath BM.: Frailty in Pediatric Liver Disease May Be Associated With an Increased Incidence of Readmissions After Pediatric Liver Transplantation. Pediatr Transplant 2025.
Luo Y, Fraser L, Jezykowski J, Gupta NA, Miethke AG, Taylor SA, Alonso EM, Horslen S, Kohli R, Molleston JP, Kamath BM, Guthery SL, Loomes KM, Magee JC, Rosenthal P, Valentino P, Sokol RJ, Mack CL; Childhood Liver Disease Research Network.: Interleukin 8-CXCR2-mediated neutrophil extracellular trap formation in biliary atresia associated with neutrophil extracellular trap-induced stellate cell activation. Hepatology Dec 2024.
Keefer-Jacques E, Valente N, Jacko AM, Matwijec G, Reese A, Tekriwal A, Loomes KM, Spinner NB, Gilbert MA.: Investigation of cryptic JAG1 splice variants as a cause of Alagille syndrome and performance evaluation of splice predictor tools. HGG Adv 5: 100351, Oct 2024.
Pandurangi S, Mourya R, Nalluri S, Fei L, Dong S, Harpavat S, Guthery SL, Molleston JP, Rosenthal P, Sokol RJ, Wang KS, Ng V, Alonso EM, Hsu EK, Karpen SJ, Loomes KM, Magee JC, Shneider BL, Horslen SP, Teckman JH, Bezerra JA; Childhood Liver Disease Research Network.: Diagnostic accuracy of serum matrix metalloproteinase-7 as a biomarker of biliary atresia in a large North American cohort. Hepatology 80: 152-162, Jul 2024.
Gilbert MA, Keefer-Jacques E, Jadhav T, Antfolk D, Ming Q, Valente N, Shaw GT, Sottolano CJ, Matwijec G, Luca VC, Loomes KM, Rajagopalan R, Hayeck TJ, Spinner NB.: Functional characterization of 2,832 JAG1 variants supports reclassification for Alagille syndrome and improves guidance for clinical variant interpretation. Am J Hum Genet 111: 1656-1672, Jul 2024.
Chapin CA, Diamond T, Perez A, Kreiger PA, Loomes KM, Behrens EM, Alonso EM.: Identification of pediatric activated T-cell hepatitis using clinical immune studies. Clin Res Hepatol Gastroenterol 48: 102407, Jun 2024.
Van Hove JLK, Friederich MW, Strode DK, Van Hove RA, Miller KR, Sharma R, Shah H, Estrella J, Gabel L, Horslen S, Kohli R, Lovell MA, Miethke AG, Molleston JP, Romero R, Squires JE, Alonso EM, Guthery SL, Kamath BM, Loomes KM, Rosenthal P, Mysore KR, Cavallo LA, Valentino PL, Magee JC, Sundaram SS, Sokol RJ; Childhood Liver Disease Research Network (ChiLDReN).: Protein biomarkers GDF15 and FGF21 to differentiate mitochondrial hepatopathies from other pediatric liver diseases. Hepatol Commun 8: e0361, Jan 2024.