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Richard Aplenc, MD, PhD, MSCE

Richard Aplenc, MD, PhD, MSCE

faculty photo
Associate Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
CTRB Room 4018
3501 Civic Center Blvd
Philadelphia, PA 19104
Office: 2674267252
Education:
A.B. (Classics)
Princeton University, 1988.

University of Pennsylvania, Post-Baccalaureate Pre-Health Program, 1989.
MD
University of Virginia, 1994.
MSCE (Clinical Epidemiology and Biostatistics)
University of Pennsylvania, 2002.
PhD (Epidemiology)
University of Pennsylvania, 2011.
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Selected Publications

Freedman Jason L, Faerber Jennifer, Kang Tammy I, Dai Dingwei, Fisher Brian T, Huang Yuan-Shung, Li Yimei, Aplenc Richard, Feudtner Chris: Predictors of antiemetic alteration in pediatric acute myeloid leukemia. Pediatric blood & cancer 61(10): 1798-805, Oct 2014.

Goodman Elizabeth K, Reilly Anne F, Fisher Brian T, Fitzgerald Julie, Li Yimei, Seif Alix E, Huang Yuan-Shung, Bagatell Rochelle, Aplenc Richard: Association of Weekend Admission With Hospital Length of Stay, Time to Chemotherapy, and Risk for Respiratory Failure in Pediatric Patients With Newly Diagnosed Leukemia at Freestanding US Children's Hospitals. JAMA pediatrics Aug 2014.

Gamis Alan S, Alonzo Todd A, Meshinchi Soheil, Sung Lillian, Gerbing Robert B, Raimondi Susana C, Hirsch Betsy A, Kahwash Samir B, Heerema-McKenney Amy, Winter Laura, Glick Kathleen, Davies Stella M, Byron Patti, Smith Franklin O, Aplenc Richard: Gemtuzumab Ozogamicin in Children and Adolescents With De Novo Acute Myeloid Leukemia Improves Event-Free Survival by Reducing Relapse Risk: Results From the Randomized Phase III Children's Oncology Group Trial AAML0531. Journal of clinical oncology : official journal of the American Society of Clinical Oncology Aug 2014.

Seif A. E., Fisher B. T., Li Y., Torp K., Rheam D. P., Huang Y. S., Harris T., Shah A., Hall M., Fieldston E. S., Kavcic M., Vujkovic M., Bailey L. C., Kersun L. S., Reilly A. F., Rheingold S. R., Walker D. M., Aplenc R.: Patient and hospital factors associated with induction mortality in acute lymphoblastic leukemia. Pediatr Blood Cancer 61(5): 846-52, May 2014.

Oshrine Benjamin R, Olsen Molly N, Heneghan Mallorie, Wertheim Gerald, Daber Robert, Wilmoth Donna M, Biegel Jaclyn A, Pawel Bruce, Aplenc Richard, King Rebecca L: Acquired isochromosome 12p, somatic TP53 and PTEN mutations, and a germline ATM variant in an adolescent male with concurrent acute megakaryoblastic leukemia and mediastinal germ cell tumor. Cancer genetics 207(4): 153-9, Apr 2014.

Aplenc R., Zhang M. J., Sung L., Zhu X., Ho V., Cooke K., Dvorak C., Hale G., Isola L., Lazarus H., McCarthy P., Olsson R., Pulsipher M., Pasquini M., Bunin N.: Effect of body mass in children with hematologic malignancies undergoing allogeneic bone marrow transplantation. Blood Page: [Epub ahead of print] Apr 2014.

Hagleitner M. M., Coenen M. J., Aplenc R., PatiƱo-Garcia A., Chiusolo P., Gemmati D., De Mattei M., Ongaro A., Krajinovic M., Hoogerbrugge P. M., Vermeulen S. H., Te Loo D. M.: The role of the MTHFR 677C>T polymorphism in methotrexate-induced liver toxicity: a meta-analysis in patients with cancer. Pharmacogenomics J 14(2): 115-9, Apr 2014.

Wray Lisa, Vujkovic Marijana, McWilliams Thomas, Cannon Shannon, Devidas Meenakshi, Stork Linda, Aplenc Richard: TPMT and MTHFR genotype is not associated with altered risk of thioguanine-related sinusoidal obstruction syndrome in pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group. Pediatric blood & cancer Apr 2014.

Diamond J. M., Akimova T., Kazi A., Shah R. J., Cantu E., Feng R., Levine M. H., Kawut S. M., Meyer N. J., Lee J. C., Hancock W. W., Aplenc R., Ware L. B., Palmer S. M., Bhorade S., Lama V. N., Weinacker A., Orens J., Wille K., Crespo M., Lederer D. J., Arcasoy S., Demissie E., Christie J. D.; Lung Transplant Outcomes Group.: Genetic variation in the prostaglandin e2 pathway is associated with primary graft dysfunction. Am J Respir Crit Care Med 89(5): 567-75, Mar 2014.

Seif A. E., Walker D. M., Li Y., Huang Y. S., Kavcic M., Torp K., Bagatell R., Fisher B. T., Aplenc R.: Dexrazoxane exposure and risk of secondary acute myeloid leukemia in pediatric oncology patients. Pediatr Blood Cancer Page: [Epub ahead of print] Mar 2014.

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Last updated: 09/22/2014
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