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Phyllis A. Gimotty, Ph.D

Phyllis A. Gimotty, Ph.D

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Professor of Biostatistics in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Department: Biostatistics and Epidemiology
Graduate Group Affiliations

Contact information
Department of Biostatistics and Epidemiology
University of Pennsylvania Perelman School of Medicine
423 Guardian Drive, 631 Blockley Hall
Philadelphia, PA 19104-6021
Office: 215-573-5153
Fax: 215-573-4865
Education:
B.A. (Sociology)
University of Michigan, Ann Arbor, MI, 1970.
M.A. (Statistics)
University of Michigan, Ann Arbor, MI , 1972.
Ph.D. (Biostatistics)
University of Michigan, Ann Arbor, MI , 1984.
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Selected Publications

Cintolo JA, Gimotty P, Blair A, Guerry D, Elder DE, Hammond R, Elenitsas R, Xu X, Fraker D, Schuchter LM, Czerniecki BJ, Karakousis G: Local immune response predicts survival in patients with thick (T4) melanomas. Annals of Surgical Oncology 20(11): 3610-3617, Oct 2013.

Balch CM, Soong SJ, Gershenwald JE, Thompson JF, Coit DG, Atkins MB, Ding S, Cochran AJ, Eggermont AM, Flaherty KT, Gimotty PA, Johnson TM, Kirkwood JM, Leong SP, McMasters KM, Mihm MC Jr, Morton DL, Ross MI, Sondak VK: Age as a prognostic factor in patients with localized melanoma and regional metastases. Annals of Surgical Oncology 20(12): 3961-3968, Nov 2013.

Roesch A, Vultur A, Bogeski I, Wang H, Zimmermann KM, Speicher D, Körbel C, Laschke MW, Gimotty PA, Philipp SE, Krause E, Pätzold S, Villanueva J, Krepler C, Fukunaga-Kalabis M, Hoth M, Bastian BC, Vogt T, Herlyn M: Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells. Cancer Cell 23(6): 811-825, Jun 2013.

Vultur A, Villanueva J, Krepler C, Rajan G, Chen Q, Xiao M, Li L, Gimotty PA, Wilson M, Hayden J, Keeney F, Nathanson KL, Herlyn M: MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines. Oncogene 33(14): 1850-1861, Apr 2013.

Cuker A, Gimotty PA, Crowther MA, Warkentin TE: Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis. Blood 120(20): 4160-4167, Nov 2012.

Nunez-Cruz S, Gimotty PA, Guerra MW, Connolly DC, Wu YQ, DeAngelis RA, Lambris JD, Coukos G, Scholler N: Genetic and pharmacologic inhibition of complement impairs endothelial cell function and ablates ovarian cancer neovascularization. Neoplasia 14(11): 994-1004, Nov 2012.

Kumar SM, Liu S, Lu H, Zhang H, Zhang PJ, Gimotty PA, Guerra M, Guo W, Xu X: Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation. Oncogene 31(47): 4898-4911, Nov 2012.

Wong GS, Habibollahi P, Heidari P, Lee JS, Klein-Szanto AJ, Waldron TJ, Gimotty P, Nakagawa H, Taylor PR, Wang TC, Mahmood U, Rustgi AK: Optical imaging of periostin enables early endoscopic detection and characterization of esophageal cancer in mice. Gasroenterology 144(2): 294-297, Feb 2013.

Xu X, Chen L, Guerry D, Dawson PR, Hwang WT, Van Belle P, Elder DE, Zhang PJ, Ming ME, Schuchter LM, Gimotty PA: Lymphatic invasion is independently prognostic of metastasis in primary cutaneous melanoma. Clinical Cancer Research 18(1): 229-237, Jan 2012.

Naganuma S, Whelan KA, Natsuizaka M, Kagawa S, Kinugasa H, Chang S, Subramanian H, Rhoades B, Ohashi S, Itoh H, Herlyn M, Diehl JA, Gimotty PA, Klein-Szanto AJ, Nakagawa H: Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma. American Journal of Cancer Research 2(4): 459-475, Jun 2012.

Gamerman V, Karakousis G, Guerry D, Gimotty PA: Conditional survival (CS) in patients with stage II melanoma. Published abstract, American Society for Clinical Oncology May 2012.

Yang K, Mooney C, Spahlinger G, Schuetze S, Arias-Pulido H, Verschraegen C, Gimotty P, Buckanovich R: DR6 as a diagnostic and predictive biomarker in adult sarcoma. PLOS ONE 7(5): e36525, May 2012.

Tang HY, Beer LA, Chang-Wong T, Hammond R, Gimotty P, Coukos G, Speicher DW: A xenograft mouse model coupled with in-depth plasma proteome analysis facilitates identification of novel serum biomarkers for human ovarian cancer. Journal of Proteome Research 11(2): 678-691, Feb 2012.

Chu CS, Boyer J, Schullery DS, Gimotty PA, Gamerman V, Bender J, Levine BL, Coukos G, Rubin SC, Morgan MA, Vonderheide RH, June CH: Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission. Cancer Immunology,Immunotherapy 61(5): 629-641, May 2012.

Yun SJ, Gimotty PA, Hwang WT, Dawson P, Van Belle P, Elder DE, Elenitsas R, Schuchter L, Zhang PJ, Guerry D, Xu X: High lymphatic vessel density and lymphatic invasion underlie the adverse prognostic effect of radial growth phase regression in melanoma. The American Journal of Surgical Pathology 35(2): 235-242, Feb 2011.

Thompson JF, Soong SJ, Balch CM, Gershenwald JE, Ding S, Coit DG, Flaherty KT, Gimotty PA, Johnson T, Johnson MM, Leong SP, Ross MI, Byrd DR, Cascinelli N, Cochran AJ, Eggermont AM, McMasters KM, Mihm MC, Morton DL, Sondak VK: Prognostic significance of mitotic rate in localized primary cutaneous melanoma: an analysis of patients in the multi-institutional American Joint Committee on Cancer melanoma staging database. Journal of Clinical Oncology 29(16): 2199-2205, Jun 2011.

Facciabene A, Peng X, Hagemann IS, Balint K, Barchetti A, Wang L-P, Gimotty PA, Gilks CB, Lal P, Zhang L, Coukos G: Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature 475(7355): 226-230, Jul 2011.

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Last updated: 11/19/2014
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